SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2025
·
IF 4.6
Yi Zhang,Ziyi Zhao,Hui Wu
Fluorescence nanosensor based on carbon dots (CDs) is an up-and-coming platform for precise determination of isoliquiritigenin (ISO), ensuring human health and environmental safety. Herein, biomass nitrogen-doped carbon dots (BN-CDs) were assembled through a one-pot hydrothermal platform with lemon peel and melamine as precursors, which could be developed as distinguished sensors to detect ISO. The structure and optical properties of BN-CDs were explored in detail through some analytical methods. The BN-CDs indicated excellent UV resistance performance and biocompatibility. Moreover, after the addition of ISO, the blue fluorescence could be significantly quenched, and an eminent linear relationship was acquired between ln(F 0 /F) and ISO concentrations. The fitting equation was ln(F 0 /F) = 0.054[ISO] + 0.0085 (R 2 = 0.9978) with the concentration range of 0–50 μM. 0.056 μM of detection limit was obtained based on the 3b/k. This nanosensor was successfully carried out in real samples with satisfactory recoveries of 93.3–103.9 %. This research offered a theoretical foundation towards ISO determination via blue-emitting CDs and indicated huge application potential.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ELECTROCHIMICA ACTA
·
2026
·
IF 5.8
Qiao Wan,Yajun Li,Yahong Su,Wenqing Jia,Jiang Zhu,Qiang Yu,Zhen Chen,Lingli Lei,Yuanyuan Zhang
This study aims to develop a high-performance, low-cost non-enzymatic electrochemical sensing materials for glucose detection, addressing the limitations of existing technologies. A three-dimensional porous hierarchical layered-nanoflower heterostructured CuCoP/MXene composite was synthesized through in situ growth of CuCo-MOF nanoflowers on Ti 3 C 2 -MXene via a one-step hydrothermal method, followed by oxidation and phosphidation treatments. This unique architecture significantly increases the specific reactive surface area, exposes abundant active sites, and provides sufficient interfacial regions for glucose oxidation. The synergistic effect between copper (Cu) and cobalt (Co) further enhances the electrocatalytic performance. Meanwhile, MXene serves as a conductive scaffold that not only facilitates electron transfer but also promotes the diffusion and adsorption of glucose molecules, owing to its excellent conductivity and continuous interlayer channels. The fabricated sensor exhibits an extensive linear detection range (0.5-6000 μM), high sensitivity (1408.49 μA mM -1 ·cm -2 ), a low detection limit (0.14 μM, S/N=3), along with excellent selectivity, reproducibility, and stability, together with a swift response time (3 s). Moreover, the sensor has been successfully applied to the accurate detection of glucosein samples of serum, showing high reliability and promising practical value.
✓ 已验证
产品关联
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2026
·
IF 12.5
Zhen Zhang,Xiaojian Tian,Yuxiao Sun,Dandan Han,Bang Gu,Dan Wu,Armin Rezayan,Xian Wu,Jingpeng Zhao,Jianshe Wang,Tianliang Lu,Renfeng Nie,Xiaoqin Si,Chunbao Xu,Yongsheng Zhang
Vanadium-based catalysts are widely used in the oxidation of carbohydrates to produce formic acid (FA), a promising liquid organic hydrogen carrier, but still suffers from low yield due to the formation of CO 2 . This study found that the spatially isolated VO x on active carbon (AC) can significantly increase FA yield from 43.5 to 72.9% in glucose oxidation compared with free VO x . Two specific roles of AC were revealed. Firstly, the oxygenated functional groups, high surface area and abundant microporous of AC, play a crucial role in the atomic dispersion of VO x , resulting in a heterogeneous, single-site VO x -AC catalyst. The isolated VO x site favors the oxidative C C bond cleavage in glucose via a stepwise α-cleavage pathway, thus improving FA selectivity. Secondly, the conductive AC acts as an electron buffer, which accelerates the catalytic redox cycle between V 5+ and V 4+ of the isolated VO x sites, thus increasing the reaction activity. The prepared single-site VO x -AC catalyst is reusable and can generate a concentrated FA solution (4.7 wt%) by simple filtration of the solid catalyst. This work presents a simple method for the production of H 2 energy carrier from biomass and provides a fundamental basis for designing efficient catalytic systems for aqueous-phase oxidation reactions.
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
·
2026
·
IF 4.1
Qing Yang,Jingsen Zhang,Mingyi Lv,Chuanjie Chen,Yue Hua,Hong Li,Lanbo Di
Regulating the cobalt valence state is a crucial strategy for enhancing nonenzymatic glucose detection. In this study, two self-supported Co 3 O 4 nanocomposites were fabricated on plasma-pretreated carbon cloth (CC P ) by electrodepositing an α-Co(OH) 2 precursor followed by either plasma treatment yielding Co 3 O 4 /CC P -P or calcination yielding Co 3 O 4 /CC P -C. Structural characterization reveals that plasma pretreatment enriches the CC P surface with abundant oxygen-containing functional groups (OCGs), significantly improving its hydrophilicity. In addition, the Co 3 O 4 /CC P -C exhibits a phase-pure structure enriched with multiple Co 3+ and surface-adsorbed oxygen (O Ads ). These properties coupled with its rapid electron-transfer capability significantly promote the glucose oxidation reaction. Compared with Co 3 O 4 /CC P -P, the Co 3 O 4 /CC P -C electrode presents markedly higher electrocatalytic activity toward glucose oxidation, featuring superior sensitivities of 6380 μA·mM −1 ·cm −2 (0.05–0.4 mM) and 2070 μA·mM −1 ·cm −2 (0.4–1.4 mM), along with a lower limit of detection (2.9 μM). The Co 3 O 4 /CC P -C electrode also exhibits excellent selectivity, good preparation repeatability (relative standard deviation (RSD) = 2.14%), operational repeatability (RSD = 1.36%) and favorable stability (RSD = 2.40%). This study provides a promising approach for developing efficient non-enzymatic glucose oxidation Co-based electrocatalysts, and gets insights into the influence mechanism by engineering the Co valence state.
✓ 已验证
产品关联
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2026
·
IF 13.2
Wanning Gao,Shengyuan Shi,Youcong Li,Fangyuan Liu,Yudi Cheng,Jie Zheng,Meng Qiao,Shuai Yuan,Xing Zhang
The spatial organization of enzymes in natural cells enables efficient metabolic cascades through localized microenvironments and controlled intermediate diffusion. Mimicking this compartmentalized architecture in artificial systems remains a key challenge in biocatalysis. Here, we introduce a DNA-mediated self-assembly strategy to construct the biomimetic core-satellite structure of metal-organic frameworks (MOFs) that spatially organize multiple enzymes into defined compartments. In this system, DNA bridges larger “core” MOFs and smaller “satellite” MOFs, forming ordered assemblies with tunable microenvironments tailored for individual enzymes. Using glucose oxidase (GOx) and horseradish peroxidase (HRP) as a model cascade, we demonstrate that the core-satellite structure facilitates substrate diffusion, mitigates inhibition by intermediates, and enhances overall catalytic efficiency. This platform was further applied to support multi-enzyme cascades, including the two-enzyme system of N -acetyl hexosamine 1-kinase (NahK)/UDP- N -acetylgalactosamine pyrophosphorylase (GlmU) for glycosyl donor synthesis, and the three-enzyme system of β-galactosidase (β-Gal)/GOx/HRP for sequential cascade catalysis. Compared to the single MOF system, spatially compartmentalized MOFs exhibit up to 34-fold higher activity and improved thermal, solvent, and operational stability. This work provides a versatile platform for the design of cell-inspired biocatalytic systems and underscores the potential of DNA-guided MOF assembly in constructing programmable multi-compartment enzyme reactors.
✓ 已验证
产品关联
DOI
高影响因子
MICROCHEMICAL JOURNAL
·
2026
·
IF 5.1
Zongmei Huang,Cong-Ting Wu,Jing Li,Lu-Shuang Li
Illegal addition of curcumin (Cur) in food poses a significant public health threat, creating an urgent need for sensitive, reliable detection methods. In this work, dual-emission carbon dots (DCDs) were synthesized via a one-step hydrothermal method with Rose Bengal and melamine as raw materials. Based on the distinct fluorescence responses of DCDs to Cur at two characteristic wavelengths, a novel ratiometric fluorescence sensor for Cur detection was constructed. The emission at 432 nm is primarily governed by inner filter effect, while quenching at 532 nm is associated with the fluorescence resonance energy transfer. The sensor shows a robust linear range of 0.1–20 μM with a limit of detection of 0.089 μM. The sensor was successfully employed for the detection of Cur in various food samples, including chili, ginger, and mustard powder, achieving recovery rates between 92.75% and 110.00%. This work enriches CDs synthesis strategies and provides a sensitive, cost-effective, rapid method for Cur detection, supporting food industry monitoring needs.
✓ 已验证
产品关联
DOI
高影响因子
MICROCHEMICAL JOURNAL
·
2026
·
IF 5.1
Mengfei Xu,Ziyi Ren,Xinyao Huo,Xiyu Zhang,Fang Yang,Feifei Peng,Geng Zhang,Xuerong Chen,Wei Wu
Regulating the morphology of composite materials and simplifying their preparation processes are critical for enhancing material performance and broadening application prospects, especially for metal-organic framework (MOF)-based nanocomposites. Conventional synthesis methods for MOF/graphene composites (e.g., solvothermal methods) often suffer from high energy consumption (high temperature), long reaction times (up to 24 h), and large MOF particle sizes (micrometer scale), which limit active site exposure, electron transfer efficiency, and practical applicability. Herein, we report a low-energy, efficient strategy to fabricate nanosized HKUST-1 decorated graphene nanosheet (nano-HKUST-1@GS) composites via in situ growth, which requires only 15 min at room temperature. This strategy yields uniformly distributed nano-HKUST-1 particles (∼46 nm) with intimate interfacial contact with GS. Benefiting from the synergistic interplay between nanosized HKUST-1 (abundant exposed active sites) and conductive GS (accelerated electron transfer), the nano-HKUST-1@GS composite exhibits superior electrochemical performance compared to individual components or their physical mixtures. When applied as an electrocatalyst for glucose oxidation, the constructed non-enzymatic sensor achieves a high sensitivity of 2065 μA mM −1 cm −2 , a wide linear range (0.5–2607 μM), and an ultralow detection limit of 0.11 μM (S/N = 3), outperforming most reported counterparts. Furthermore, this sensor successfully quantifies glucose in human serum samples, validating its practical utility. This work not only provides a low-energy, efficient approach for constructing nanosized MOF/graphene heterostructures but also develops a sensitive, reliable enzyme-free glucose detection platform, holding promise for advancing MOF-based composite synthesis and clinical diagnostics.
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF ENVIRONMENTAL MANAGEMENT
·
2026
·
IF 9.2
Moyan Qin,Qi Wang,Zhengmin Hu,Taoyi Chen,Hui Lin,Kai Sun
Laccase catalysis represents a promising green strategy for mitigating endocrine-disrupting chemicals (EDCs) and sequestering organic carbon in agroecosystems. However, the mechanistic role of root-exuded metabolites in modulating laccase-catalyzed EDC rhizoremediation within maize ( Zea mays L.) systems remains poorly understood. Here, we probed the influence of maize root exudates (M-REs) on laccase-catalyzed EDC single-electron oxidation and subsequent contaminant uptake at environmentally relevant concentrations. Relative to control treatments without M-REs, supplementation with 10−80 mg L −1 M-REs suppressed laccase-catalyzed bisphenol A transformation, whereas 5−10 mg L −1 M-REs enhanced the transformation of 17 β -estradiol. Covalent co-dimers were identified as reaction products between EDCs and key constituents of M-REs, including phenolic acids (vanillic acid, ferulic acid, protocatechuic acid) and amino acids (glutamic acid, phenylalanine). Notably, prolonged laccase-catalyzed polymerization led to the formation of highly complex, insoluble co-polymers via cross-linking of EDCs with exudate components. These precipitated polymers exhibited low bioavailability and minimal mobility, resulting in significantly reduced EDC phytotoxicity, as evidenced by an improved germination index. Pot trials further demonstrated that laccase-regulated rhizoremediation decreased root uptake rate constants by 51.72% for E2 and 20.59% for BPA compared to enzyme-deficient controls. This efficient sequestration markedly limited the translocation of EDCs to aboveground tissues, thereby minimizing their potential entry into the food chain. Collectively, these findings elucidate the mechanistic role of M-REs in modulating laccase-catalyzed EDC polymerization and subsequent uptake, thereby advancing the development of sustainable and eco-friendly rhizoremediation strategies to support safe agricultural production.
✓ 已验证
产品关联
DOI
高影响因子
Catalysts
·
2026
·Vol. 16
·期 3
·264
·
IF 4.5
Chenfeng Li,Jiahao Ju,Beizhan Li,Jilei Xu,Xin Su,Zuoyi Xiao,Qingda An,Jiahui Huang
5-Methoxymethyl-2-furfural (MMF) serves as a crucial biobased platform molecule that can be transformed into various high-value chemicals and biobased polyester monomers. However, the current production of MMF still faces several challenges, such as low yield and prolonged reaction time. In this study, we prepared a series of amide-modified strongly acidic resin catalysts and discovered that they have a higher efficiency in converting fructose to prepare MMF in 1-Butyl-3-methylimidazolium chloride ([BMIM]Cl) and methanol. Among the synthesized catalysts, DB757-NMP demonstrated superior performance, achieving an MMF yield of approximately 61.5% under the optimized conditions, with a combined yield of HMF and MMF reaching about 66.6%. The catalyst formation mechanism was analyzed using FTIR, and NMR, confirming the transformation of proton between NMP and the sulfonic acid groups of the resin, which collectively promoted the conversion of fructose to MMF. In addition, we investigated main reasons for catalyst deactivation and successfully restored catalytic activity through regeneration. The regenerated catalyst could be reused for three times with only a slight decrease in MMF yield. The results suggested that DB757-NMP is a more sufficient and recyclable catalyst for the production of MMF from fructose. This work presented a simple and environmentally benign approach for the synthesis of MMF.
✓ 已验证
产品关联
DOI
高影响因子
ACS Omega
·
2026
·
IF 5.2
Kermue Vasco Jarnda,Heng Dai,Huiting Hu,Yuan Tian,Richmond Anaman,Pian Wu,Ping Ding
Recent advancements in microfluidic paper-based analytical devices (μPADs) have demonstrated their significant potential for point-of-care testing (POCT), particularly in low-resource settings. These devices are especially promising for monitoring glucose levels in patients with diabetes, offering a cost-effective and portable solution. However, one of the primary challenges hindering the widespread adoption of smartphone-coupled μPADs has been their sensitivity to varying ambient lighting conditions, which can interfere with accurate colorimetric detection. To address this issue, researchers have introduced a novel approach involving a metal–organic framework (MOF), specifically Co-TCPP (Fe) [cobalt Fe(III) meso-tetra(4-carboxyphenyl) porphyrin chloride], synthesized using a straightforward method. Co-TCPP (Fe) exhibits remarkable peroxidase-like activity when exposed to hydrogen peroxide (H2O2), enabling it to interact effectively with classic chromogenic substrates and thus improving the colorimetric reaction crucial for accurate glucose detection. In this study, the team developed paper-based μPADs that incorporate the Co-TCPP (Fe) MOF, allowing it to accurately detect glucose levels across a wide concentration range. The limit of detection (LOD) achieved was 5.3 μM, with a linear detection range from 5 to 750 μM. This innovation addresses previous concerns regarding the impact of environmental lighting fluctuations and varying shooting angles, ensuring the reliability of glucose measurements under uncontrolled conditions. By integrating this algorithm into a smartphone-coupled μPAD system, the researchers have created a portable, high-resolution platform that delivers dependable results, even in challenging and fluctuating environments. This breakthrough marks a significant step toward enhancing the practicality and accessibility of glucose monitoring in resource-constrained settings, providing a valuable tool for both clinical and everyday use.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
INORGANIC CHEMISTRY
·
2026
·Vol. 65
·期 35
·20348-20360
·
IF 4.6
Wu Huifang,Zhang Jiaxing,Zhang Tiantian,Khaleel Maryam Tariq,Yan Xin,Zhan Jiayao,Wang Jincong,Guo Qiang,Guo Xinwen,Ren Limin
Hierarchical
Sn-containing self-pillared pentasil (Sn-SPP) zeolites,
with their unique nanosheet intergrowth architecture, are highly attractive
for biomass upgrading. However, direct Sn incorporation is hindered
by kinetic mismatches between Sn and Si. Premature Si–O–Sn
linkages disrupt the ordered nucleation, resulting in sluggish crystallization,
poor Sn integration, and a loosely stacked, unstable structure. Herein,
we report a “sustained Sn release” strategy using tetraethylenepentamine
(TEPA) as a multifunctional additive. TEPA transiently coordinates
Sn species into soluble complexes, creating a sustained-release reservoir
that mediates TEPA-mediated Sn buffering to prevent premature Si–O–Sn
formation and enables silicate preorganization. Simultaneously, TEPA
cotemplates with TBAOH to direct denser nanosheet stacking, reducing
external defects and reinforcing framework integrity. This dual-function
mechanism expands the synthesis window to Si/Sn = 50, shortens crystallization
time from weeks to days, and tolerates reduced structure-directing
agent loadings. The resulting Sn-SPP achieves 75.3% glucose conversion
with 81.1% fructose selectivity in glucose isomerization, outperforming
conventional microporous Sn-MFI. Moreover, it retains >95% crystallinity
and acid site density after harsh steaming. This work establishes
a cotemplating approach for hierarchical zeolites that couples kinetic
regulation of heteroatom speciation with structural control.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ANALYTICAL CHEMISTRY
·
2025
·
IF 6.7
Wei Yang,Wenbo Jiang,Qiming Huang,Tianchi Leng,Leyi Zhang,Yaxin Zhang,Shan Chen,Yuanqing Gao,Yimin Fang
The urgent need for rapid, low-cost pathogen diagnostics in resource-limited settings drives the development of point-of-care technologies that balance sensitivity, specificity, simplicity, and cost. Here, we present a biosensing platform by integrating an aptamer-poly-T DNA strand for rapidly loading copper nanoclusters (Cu NCs) on the target pathogen and size-exclusion filtration to concentrate the pathogen onto a membrane, enabling ultrasensitive visual detection of low-abundance pathogens within 20 min by naked eyes. The aptamer domain enables the pathogen-specific recognition (validated by Salmonella and SARS-CoV-2 pseudovirus), while the poly-T template facilitates the rapid (<5 min) loading of Cu NCs to the target. The Cu NC-labeled target pathogens were then concentrated on the membrane, while the matrix interferents (salts, proteins), as well as the unbound Cu NCs can be washed away from the membrane due to their relatively small sizes. The efficient release of thousands of Cu2+ from the Cu NCs enables the sensitive coloration of the membrane in the presence of TEA, yielding a 10,000-fold sensitivity gain over colloidal gold assays. This cascaded mechanism achieves a detection limit of 10 particles/μL in undiluted serum. The sensing platform is applicable to other biological particles such as exosomes (cancer biomarkers) with low cost (a per-test cost < $1). By merging molecular specificity with field-deployable robustness, this technology redefines decentralized diagnostics for emerging bacterial or viral threats, offering transformative potential for epidemic surveillance and precision public health interventions.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）