LANGMUIR
·
2026
·
IF 4.4
Mingyu Yan,Junda Guo,Keying Sun,Derui Chen,Chao Sun,Shunyu Han,Xinyu Li
Transforming industrial solid waste into functional materials is a central challenge in sustainable chemistry. Here, we report a green steam-assisted method for synthesizing mesoporous hectorite using silica extracted from coal fly ash. The synthesis proceeds under mild conditions (473.15 K, 24 h) without generating liquid waste, distinguishing it from conventional hydrothermal routes. By optimizing precursor ratio, temperature, and time, we obtain a well-ordered layered structure with approximately 4 nm mesopores and a high specific surface area (54 m2/g). The resulting hectorite exhibits exceptional adsorption capacities toward Crystal Violet (657.8 mg/g) and Cu2+ (82.47 mg/g), with rapid kinetics (10 min) and stable reusability over five cycles. Mechanistic studies reveal synergistic adsorption involving ion exchange, electrostatic attraction, and surface complexation, while kinetic and thermodynamic analyses confirm spontaneous, endothermic chemisorption. This work establishes a closed-loop, waste-to-resource strategy that integrates fly ash valorization, green synthesis of layered silicates, and high-performance water remediation.
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JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
·
2026
·Vol. 37
·期 19
·1481
·
IF 3.2
Zhang Xiaomin,Qin Mingjun,Tang Weilei,Pang Juan,Lyu Yue,Chen Cheng
Conductive adhesives (ECAs) are critical for advanced electronic packaging, but the high cost of silver fillers limits their widespread application. This study presents a hybrid filler strategy combining silver-coated copper (Ag@Cu) nanoparticles with a low content of silver flakes to achieve high electrical conductivity at reduced cost. The Ag@Cu particles were synthesized via a two-step wet chemical reduction method, yielding a well-defined core–shell structure with a dense silver coating that prevents copper oxidation. A series of ECAs were prepared with silver flakes and Ag@Cu nanoparticles at a fixed total filler loading of 70%. The results demonstrate that the optimal silver flake content is 4%, at which the ECA exhibits the lowest volume resistivity of 3 × 10⁻ 4 Ω·cm. The prominent conductivity improvement stems from synergistic geometric regulation. Low loading silver flakes serve as conductive bridges to fill interparticle gaps and construct hybrid point-to-face contact, verified by SEM. The silver flake composite retains favorable shear strength and thixotropy for screen printing. A circuit test with printed films lit an LED, validating its feasibility for flexible circuits. This work develops low cost, high-performance ECAs using Ag@Cu nanoparticles and silver flakes, achieving a balance between excellent conductivity and reduced material cost.
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Advanced Science
·
2026
·
IF 14.1
Meng Zheng,Changyu Liu,Qin Xia,Arndt F Schilling,Jiawei Jiang,Renpeng Peng,Zixing Shu,Tian Ma,Danni Luo,Yaoyu Zhang,Yibo Fan,Xuyuan Zhang,Song Li,Kai Wang,Wentao Ke,Yuan Xiong,Yuanli Zhu,Fangzhi Mou,Jun Xiao,Hao Zhu
Osteoarthritis (OA) is a prevalent degenerative joint disease with limited effective treatment options. Joint inflammatory pain is a primary reason patients seek care, but systemic drug administration often causes severe side effects, while intra‐articular injection suffers from rapid clearance and poor tissue penetration. Herein, we develop nanozyme‐based Janus nanomotors loaded with metformin (MET) for reactive oxygen species (ROS)‐targeted therapy in OA. Leveraging intrinsic superoxide dismutase (SOD) and catalase (CAT) enzymatic activity, these nanomotors harness pathologically elevated ROS within the articular microenvironment as chemical fuel, achieving self‐propelled deep penetration into both cartilage and synovial tissue. This mechanism facilitates simultaneous on‐the‐move ROS scavenging and sustained deep‐tissue MET release, which further restores redox homeostasis and protects chondrocytes by regulating the NRF2/KEAP1 signaling pathway. Furthermore, the nanomotors can suppress nociceptive signaling in the dorsal root ganglia (DRG), thereby alleviating joint pain and improving mobility. This research offers a novel and efficient approach for cartilage protection and arthritis pain management. ROS‐responsive NM@MET nanomotors utilize elevated ROS in osteoarthritic joints to promote deep penetration into cartilage and synovium and enable sustained metformin release. By scavenging ROS, regulating NRF2/KEAP1 signaling, protecting chondrocytes, suppressing synovial inflammation, and attenuating nociceptive signaling, NM@MET alleviates pain and improves joint function.
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Advanced Materials Technologies
·
2026
·
IF 6
Fanghua Pan,Yuwei Hao,Shouzheng Jiao,Changcheng Han,Zhengyu Chen,Lu Han,Ruping Liu,Yuanyuan Liu,Yang Zhou,Zhicheng Sun
Reliable temperature monitoring in cold chain logistics and food storage necessitates rapid detection of temperature excursions to ensure safety and quality. However, most existing approaches depend on powered sensors and complex data systems, limiting their suitability as passive, intuitive, and large area indicators for low temperature anomalies. Herein, raspberry-like low-temperature thermochromic microcapsules (RLTMs) were developed via a two-step interfacial polymerization approach as passive, large area visual indicators for low temperature monitoring. Structural analysis confirmed a hierarchical architecture with strong SiO 2 confinement, lowering the phase change onset from 12.1°C to −6°C and enabling graded thermal transitions. The RLTMs exhibited rapid, reversible color switching from −10°C to 37°C, achieving a visually distinct color difference (ΔE > 50) within 2 s at −10°C and full transition within 10 s. This high sensitivity originated from multi scale surface curvature that enhances diffuse scattering while minimizing glare. After 50 thermal cycles, the microcapsules retained fast response (<5 s) and high chromatic contrast, demonstrating excellent cycling stability. With a uniform size of 46.33 ± 5 µm, they can be directly screen printed as durable visual labels for food packaging and cold chain monitoring applications.
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ADVANCED MATERIALS
·
2026
·
IF 29.1
Bang Yu,Fu-Xing Zhao,Yi-Jian Qian,Wei Peng,Meng-Han Zhu,Chen Chen,Zong-Ying Huang,Si-Zhe Sheng,Zhen He,Jin-Long Wang
Gel electrolytes, which supply compensating ions for electrochromic reactions and serve as conductive media, are widely used in electrochromic devices (ECDs). However, the complex preparation processes for gel electrolytes often involve the use of large amounts of organic solvents and hazardous or valuable reagents, limiting their widespread adoption in ECDs. This paper presents a straightforward method for fabricating large-area hydroxypropyl methylcellulose (HPMC) gel electrolytes using a solution casting technique in an aqueous system. The addition of deep eutectic solvents (DES) and the incorporation of SiO 2 nanoparticles significantly improve the conductivity of the gel electrolytes. The resulting HPMC/DES-SiO 2 gel electrolyte exhibits high transparency (over 92% transmittance), high ionic conductivity (7.55 × 10 −4 S/cm), wide electrochemical window (±3 V), and outstanding thermal stability. The W 18 O 49 /NiO ECD assembled with HPMC/DES-SiO 2 gel electrolyte shows excellent cycling stability (maintained 94.8% of initial optical modulation after 1000 cycles) and can perform electrochromic response over a wide temperature range from −50°C to 200°C. Furthermore, the entire HPMC and up to 82.7% of LiTFSI and NMA can be recycled and reprocessed into new gel electrolytes, offering a promising solution for the future development of environmentally friendly and efficient ECDs.
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ANALYTICAL AND BIOANALYTICAL CHEMISTRY
·
2026
·
IF 4.1
Zhou Jiangshan,Zhang Shanyuan,Liu Mengfan,Wang Zhonghua,Zhou Zhi
Esophageal squamous cell carcinoma (ESCC) is a highly prevalent malignancy in China. Understanding its metabolic heterogeneity is of great significance for improving the precision of diagnosis and treatment. This study innovatively employed an adult zebrafish xenograft model, combining the spatial metabolomics and in situ derivatization method for fatty acid peroxidation products (FAPPs) based on air flow-assisted desorption electrospray ionization–mass spectrometry imaging (AFADESI-MSI) technology, to elucidate the metabolic patterns associated with ESCC and its differentiation grade. Spatial metabolomic data demonstrated that abundance alterations of glycerophospholipids and acetylated amino acids were statistically correlated with ESCC tumor formation. Levels of lysophospholipids and arachidonic acid-associated metabolites tended to increase with the progressive malignant differentiation of tumor lesions. Profiling of FAPPs showed elevated short- and medium-chain species accompanied by decreased long-chain counterparts in tumor-bearing zebrafish, which may be linked to tumor-initiated alterations in oxidative stress. Specifically, short- and medium-chain FAPPs were enriched in well-differentiated ESCC tissues, while long-chain FAPPs predominated in poorly differentiated tumors, suggestive of disparate lipid peroxidation patterns in ESCC cells at different differentiation stages. Furthermore, distinct signature metabolites were found to be specifically accumulated in the brain providing experimental clues that ESCC may remotely disturb the central nervous system metabolism of host animals. This research uncovers both tumor-induced and differentiation-dependent metabolic heterogeneity of ESCC, and validates whole-body MSI as a transformative approach to unravel tumor-host metabolic interactions. Graphical abstract
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FIBERS AND POLYMERS
·
2026
·
IF 3.1
Zhu Wenju,Peng Wei,Wang Shuolong,Xu Shuang,Ma Kai,Liu Jiarui,Yang Xiaokang,Chen Jia,Cheng Bowen
In this study, according to the design principle of intumescent flame retardant, rapeseed meal was modified into a phosphorus-nitrogen flame-retardant HPRm by using H 2 O 2 –H 3 PO 4 system, and L9(3 4 ) orthogonal experiment was designed to optimize the modification conditions. Cotton fabric was durably flame-retarded with HPRm via an optimized pad-dry-cure process. With only a 12.74% weight gain, the treated fabric achieved an LOI of 39.4% and a 34 mm damage length in the VFT. In CCT, the PHRR and THR of HPRm cotton decreased significantly. In addition, since HPRm can form multiple covalent bonds with cotton fibers, the LOI of HPRm cotton remained at 35.7% after 50 washing cycles and self-extinguished in VFT. At the same time, the results of TG, TG-IR and char residue analysis confirmed that HPRm changed the pyrolysis pathway of cotton fabric, reduced the production of combustible gas and formed a stable P/N char layer on the surface of cotton fiber, which effectively interrupted the combustion of cotton fabric. HPRm finishing somewhat reduced the fabric’s mechanical properties and softness. This work provides a feasible method for realizing the resource utilization of traditional agricultural by-products and the environmentally friendly and durable flame retardant of cotton fabrics.
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MICROCHIMICA ACTA
·
2026
·Vol. 193
·期 8
·513
·
IF 5.4
Liu Zhikuan,Diao Quan,Shang Xiaonan,Zhu Genxing,Cao Shuai,Shi Guangyuan,Jiao Mingli
Prussian blue analogs (PBA) were etched with a weak base and subsequently sulfurized to regulate the oxygen vacancy content, leading to the preparation of defect-rich spinel bimetallic oxide NiFe 2 O 4 . This approach successfully constructed a gas sensor with high response and excellent stability, and the material was systematically characterized. The results show that weak base etching regulates the morphology of PBA, and sulfur doping is employed to control the oxygen vacancy content. Gas sensing results confirmed that the modified NiFe 2 O 4 -NCs@S exhibited superior n-butanol gas sensing performance. Specifically, the sensing response of NiFe 2 O 4 -NCs@S to 100 ppm n-butanol at 275 °C reached 59.29, representing a 9.9-fold enhancement compared with NiFe 2 O 4 -PBA (response = 5.98). In addition, comprehensive tests demonstrate that the sensor possesses reliable selectivity, long-term stability and repeatability. To investigate the sensing mechanism, UV–vis spectroscopy and electrochemical characterizations were performed to verify that oxygen vacancies boost gas-sensing properties via band gap narrowing and electronic structure modulation. This work offers a novel strategy for developing high-response n-butanol gas sensors. Graphical
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JOURNAL OF NANOBIOTECHNOLOGY
·
2026
·
IF 15
Li Tingting,Zhao Yueming,Lin Mian,Hu Jiajun,Duan Kairui,Zhu Hu,Zi Taotao,Lee Bae Hoon
Obesity and its metabolic complications urgently require safe, effective, and minimally invasive interventions. Here, we engineered an injectable, self-healing hydrogel system (OCMU hydrogel) based on oxidized hyaluronic acid (OHA) and carboxymethyl chitosan (CMCS) for the localized delivery of plant-based ursolic acid (UA) loaded in mesoporous polydopamine (MPDA) nanoparticles. This system synergistically induces white adipose browning through combined photothermal therapy (PTT) and pharmacological action, effectively counteracting obesity. The OCMU hydrogel exhibited excellent self-healing properties, high UA loading capacity (81.04%), efficient photothermal conversion, and favorable biocompatibility. Mechanistically, the system promotes lipolysis, mitochondrial biogenesis, and adipose browning via activation of the AMPK/SIRT1/PGC-1α pathway, with a 439% increase in UCP1 expression in vitro. In obese mice, OCMU combined with PTT reduced body weight by 10.94% and inguinal fat by 56.32%, while significantly improving metabolic profiles and alleviating inflammation. Notably, the combination of mild PTT and naturally derived UA achieved superior anti-obesity efficacy compared to monotherapies, highlighting a favorable safety and efficacy profile. This work establishes a promising platform in which UA and mild PTT act in concert to reprogram adipocyte metabolism, offering a safe and synergistic approach to combat obesity. Graphical
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Advanced Science
·
2026
·
IF 14.1
Yixiong Ji,Wentong Yang,Di Yan,Wei Luo,Jialu Li,Shi Tang,Jintao Fu,James Bullock,Mei Gao,Xin Li,Zhancheng Li,Jun Yang,Zhenghong Xiong,Yang Peng,Pengjun Zhao,Xingzhan Wei,Haofei Shi,Paul Mulvaney,Fangyang Liu
Flexible kesterite Cu 2 ZnSn (S,Se) (CZTSSe) solar cells on metal foils are attractive for lightweight and conformable photovoltaic applications, yet their efficiencies remain significantly lower than those of rigid devices due to severe foil‐induced rear‐interface losses during high‐temperature chalcogenization. These effects include uncontrolled Mo(S,Se) formation, interfacial instability, and the emergence of blocking back‐contact barriers that hinder efficient carrier extraction. Here, we introduce a single‐crystal graphene interlayer to engineer the Mo foil/CZTSSe interface. The atomically thin graphene layer decouples absorber growth from the mechanically and chemically non‐ideal foil surface, suppressing detrimental interfacial reactions and stabilizing the rear interface. As a result, carrier extraction is enhanced, and the back‐contact barrier is reduced toward quasi‐ohmic behavior. Flexible CZTSSe solar cells with graphene‐engineered interfaces achieve a champion efficiency of 11.6% with simultaneous improvements in V OC , J SC , and fill factor. These results highlight rear‐interface stabilization as a key strategy for improving flexible kesterite photovoltaics on metal substrates. An atomically thin graphene interlayer stabilizes the rear interface of flexible CZTSSe solar cells by regulating interfacial stress, suppressing detrimental interfacial reactions, and reducing the back‐contact barrier. This strategy simultaneously improves photovoltaic performance and mechanical durability.
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Advanced Science
·
2026
·
IF 14.1
Hongyi Zhang,Jinwei Li,Shan Hua,Shengming Wu,Chenlong He,Yuan Zhu,Ming Yin,Han Zhou,Huawei Liu,Chika Hasegawa,Jun Lyu,Keyue Xiao,Hua Jiang,Yilong Wang,Yuxin Qian
During skin wound healing, complex interactions among multiple cell types and dynamic phase evolution make it difficult for biomaterial scaffolds to balance late‐healing and over‐healing, often resulting in delayed wound healing, persistent inflammatory responses, and hypertrophic scars due to spatiotemporal mismatch. Precise regulation of fibroblast‐to‐myofibroblast transformation and macrophage polarization is therefore essential yet challenging. Fibroblast activation protein (FAP) has been identified as a key bio‐cue in pulmonary and hepatic fibrosis, but whether FAP‐targeting peptide (FTP) within a biomimetic system can address this dilemma remains unclear. Here, a methacrylated hyaluronic acid hydrogel microneedle patch (CAF@MN) integrating a dual‐targeting biomimetic nanozyme system (Cu‐CeO 2 @ABs‐FTP) modified with apoptotic bodies (ABs) membranes and FTP is developed. Cu‐CeO 2 nanocomposites activate fibroblast functions and exhibit anti‐inflammatory, antibacterial, antioxidant, and pro‐angiogenic activities. The ABs membrane enables macrophage targeting and M2 polarization, while FTP specifically modulates myofibroblast activation. The microneedle architecture enhances deep local delivery and nanozyme utilization. In mouse and rabbit full‐phase wound models, the system achieves accelerated wound healing, reduced inflammation, and attenuated hypertrophic scars. Single‐cell RNA sequencing further elucidates the dual‐targeted regulatory mechanisms underlying anti‐inflammation and scar suppression. This study developed a dual‐targeting biomimetic nanozyme hybrid system (Cu‐CeO 2 @ABs‐FTP) and integrated it with HAMA hydrogel to fabricate a microneedle patch (CAF@MN). The patch promotes fibroblast‐mediated wound repair, targets macrophages to induce M2 polarization, and targets myofibroblasts to exert anti‐fibrotic effects, thereby enabling rapid, anti‐inflammatory, and scarless wound healing.
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HYDROMETALLURGY
·
2026
·
IF 6.3
Gengjin Zhang,Yanfang Huang,Longfei Jia,Tianze Chen,Yizhuang Wang,Shengpeng Su,Wenjuan Wang,Hu Sun,Guihong Han
Novel peroxo-complexation strategy was used to purify Nb-rich solution. • NbOF 5 2− transformation to NbO 2 F 5 2− greatly lowers its binding energy with MIBK. • Selectivity coefficient for Sb over Nb was enlarged by over 2300 times. • Nb 2 O 5 product met the high-purity specifications regarding Ta and Sb impurities. The efficient separation of Ta and Sb from Nb in hydrometallurgical processes remains a significant challenge due to their similar chemical behaviors. In this study, a novel peroxo-complexation strategy was introduced to enhance the selectivity of methyl isobutyl ketone (MIBK) extraction in an HF-H 2 SO 4 system. With the addition of H 2 O 2 , the extraction efficiencies of Ta and Sb reached 99.6% and 99.7%, respectively, while the co-extraction of Nb was only 2.32%. The selectivity coefficients of Sb/Nb and Ta/Nb significantly increased from 0.63 and 34.7 to 1461 and 6501, respectively. Stepwise stripping using H 2 SO 4 and pure water effectively recovered Nb and Ta/Sb from the loaded organic phase. Raman spectroscopy and quantum chemical calculations elucidated the mechanism of the enhanced separation selectivity. The peroxo-ligand selectively coordinates with Nb to transform it from NbOF 5 2− to NbO 2 F 5 2− , thereby weakening the negative surface potential of the fluorine atoms bonded to Nb. The binding energy between Nb ions and MIBK decreases from −172 kJ mol −1 to −104 kJ mol −1 , and thus the disparity in the affinity of Nb ions and Ta/Sb ions for MIBK is magnified. Overall, this peroxo-coordination approach provides an efficient and simple pathway for the effective purification of Nb solutions. Download: Download high-res image (176KB) Download: Download full-size image
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