Foods
·
2025
·Vol. 14
·期 12
·2116
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IF 5.1
Xianghui Yan,Ting Peng,Zheling Zeng,Pengbo Wang,Yifang Gao,Xuefang Wen,Jiaheng Xia,Deming Gong,Ping Yu
Medium chain triglycerides (MCTs) are regarded as an important ingredient for functional foods and nutraceuticals.Cinnamomum camphoraseed kernel oil (CCSKO) contains more than 95% medium chain fatty acids (MCFAs), which is a significantly higher level than palm kernel oil (62%) and coconut oil (55%). However, the safety assessment of CCSKO, as the only natural MCT oil rich in capric acid and lauric acid found so far in the world, has not been fully verified. The study aimed to investigate the 90-day sub-chronic oral toxicity and teratogenicity of CCSKO. In the sub-chronic oral toxicity study, no clinically significant adverse events occurred in male or female Sprague–Dawley (SD) rats with CCSKO daily administration for 13 weeks. Moreover, there were no dose–response relationships between CCSKO and body-weight gain, food intake and food utilization in male or female SD rats. No significant differences (p> 0.05) were found in the hematological properties or organ weights between the male and female SD rats. In the teratogenicity test, no toxicological signs were observed in either Wister pregnant rats or fetuses. The no-observed-adverse-effect level of CCSKO was determined to be more than 4 mL/kg body weight. These results suggested that CCSKO may be an excellent edible oil with high oral safety.
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CHEMICAL ENGINEERING JOURNAL
·
2025
·
IF 13.2
Jinming Li,Qiaoyu Li,Zhaoxiang Lu,Wenyu Wu,Xiaojun He,Zhou Yang,Yun Feng
Corneal alkali burns represent severe ocular injuries characterized by acute inflammation and long-term stromal fibrosis, potentially causing irreversible vision loss. Stem cell therapy has emerged as a promising treatment due to its regenerative and immunomodulatory properties. However, conventional cell injection methods are limited by poor cell viability, low retention rates, and injection-induced mechanical trauma, significantly impairing therapeutic outcomes. Here, we present collagen-modified chitosan porous microspheres (ColMS) as a cell-laden porous microcarrier system to enhance adipose-derived stem cells (ADSCs) delivery efficiency for corneal repair following alkali burns. The ColMS possess tunable pore sizes (~6–18 μm) and particle diameters (~163–313 μm), providing a three-dimensional scaffold to support ADSC adhesion, proliferation, and enhanced cell viability during injection. In vitro experiments confirmed that ADSC-loaded ColMS (ColMS-ADSCs) exhibits robust immunomodulatory capacity and epithelial regenerative capabilities. Using a rat corneal alkali burn model, subconjunctival injection of ColMS-ADSCs suppressed acute inflammation in the early stage and effectively reduced corneal fibrosis in the late stage, leading to substantial restoration of corneal transparency. The treatment promoted epithelial regeneration, with epithelial thickness restored to near-normal levels and decreased myofibroblast activation, as evidenced by a 1.5-fold reduction in α-SMA fluorescence intensity compared to the alkali burn group. This work demonstrate that ColMS effectively enhance stem cell delivery efficiency, offering a promising clinical strategy for the treatment of corneal alkali burns, potentially opening new avenues toward improved vision restoration.
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ACS Applied Bio Materials
·
2025
·
IF 4.7
Yuqing Zhang,Longzi Liang,Quanming Kou,Haojun Sun,Yiwei He,Lihua Li,Changsheng Shi
Embolization microspheres are widely used in transarterial chemoembolization (TACE) surgery, which improves treatment efficacy and patient survival by embolizing tumor blood vessels and locally releasing chemotherapy drugs. At present, embolized microspheres face challenges such as invisibility, valuableness, and drug loading limitations, which may affect treatment efficacy and postoperative examination. In this study, we designed multifunctional and low-cost nanoassembled agarose microspheres (NAAMs) and evaluated their drug loading and release capabilities, multimodal imaging capabilities, and biocompatibility. NAAMs are assembled from gold magnetic nanoparticles and inexpensive agarose microspheres, which are tightly bonded by chemical bonds and modified by a sulfonic acid group on the surface. NAAMs have excellent ability of rapid drug loading and slow drug release. 1 mL of NAAMs can load with 84 mg of doxorubicin (DOX) or 89 mg of irinotecan, and the drug loading process can be completed almost within 30 min, while drug release can last for more than 120 h. Meanwhile, NAAMs have outstanding imaging capabilities and can achieve sensitive X-ray imaging/magnetic resonance imaging (MRI)/Raman multimodal imaging, meeting clinical examination requirements. Cell experiments and hemolysis coagulation tests have confirmed that NAAMs have good biocompatibility. Therefore, NAAMs with multimodal imaging and high drug loading capacity have great application prospects in the TACE treatment of liver cancer and colorectal cancer liver metastases.
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Journal of Cleaner Production
·
2026
·
IF 10.7
Miao Li,Mengxiang Liu,Zihan Kong,Qiong Wu,Yuqi Liu,Sha Han,Tao Zhang,Xiaoxiao Huang
Electromagnetic pollution constitutes an emerging environmental and health threat, and the escalation is driving the search for sustainable and efficient mitigation technologies. This study presents an environmentally friendly and scalable solution through the design of composite nanofibers for effective electromagnetic pollution control. Utilizing the energy-efficient and industrially compatible solution blow spinning (SBS) technique, we successfully constructed a three-dimensional porous network within carbon fibers by integrating SiO 2 nanoparticles and in-situ pyrolyzed Co@BCN nanotubes. The design not only features SiO 2 as a dielectric modulator that optimizes impedance matching, but also induces abundant heterointerfaces with the carbon matrix and Co@BCN nanotubes, significantly enhancing interfacial polarization loss. The optimal material achieves a minimum reflection loss (RL min ) of −70.3 dB at a thickness of 1.8 mm and an effective absorption bandwidth (EAB) of 5.2 GHz at a thickness of 2.3 mm, significantly reducing material usage and promoting lightweight design. The study demonstrates that high performance and environmental sustainability can be synergized, providing a new pathway for developing next-generation green electromagnetic protection materials that align with the goals of sustainable industrial development.
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CHEMICAL ENGINEERING JOURNAL
·
2026
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IF 12.5
Danzhong Sun,Jiang Liu,Weixiao Feng,Nitong Bu,Yunhui Wen,Shuyi Sun,Yang Yang,Chen Zhang,Zhen Zhang,Shaowei Shi
Phase-change materials (PCMs) possess great potential for latent heat storage and thermal regulation, yet their practical application is often hindered by leakage during phase transitions. Here, we report an efficient strategy for PCM encapsulation based on the co-assembly of cellulose nanocrystals and oil-soluble dimethyl distearylammonium chloride, which stabilizes the water-paraffin wax (PW) interface. Cellulose nanocrystal surfactants (CNCSs) are formed in situ at the interface, where their high interfacial activity and jammed multilayer structure enable the preparation of stable PW-in-water emulsions. Freeze-drying of these emulsions yield PCM microcapsules with robust CNCS shells that can effectively prevent leakage during heating. Polymerization of the emulsion continuous phase produces phase change hydrogels with uniformly distributed PCM microcapsules, exhibiting excellent thermal insulation, heat-regulation, and thermal-protective properties.
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Journal of Environmental Chemical Engineering
·
2026
·Vol. 14
·期 2
·121811
·
IF 7.5
Xiuchan Xiao,Jun Wang,Huamei He,Zhicheng Feng,Chaoran Duan,Jungang Yuan,Ya Liu
The high treatment costs and substantial energy consumption associated with high-salinity fracturing flowback fluids remain critical bottlenecks restricting the development of shale gas. This study constructed a functionalized layered oil-water hydrogel solar interfacial evaporator (FG-SWE), aiming to achieve low energy consumption and zero emission treatment of high-salinity fracturing flowback fluids. The evaporator was synthesized via one-pot polymerization and consists of three functional layers (top: MXene, middle: 12-hydroxystearic acid (HSA)-based, bottom: porous), each responsible for light absorption, thermal management, and water transport, respectively. Results showed that under one sun irradiation, FG-SWE demonstrated an evaporation rate of 2.80 kg m −2 h −1 and a photothermal conversion efficiency over 95 % in 10 wt% standard saline waters, with the hydrophobic area ratio of the evaporation interface set at 30 %. Furthermore, the phase-change heat storage layer has a melting enthalpy of 125.8 kJ kg −1 , enabling continuous nighttime evaporation with a daily water production of 17 kg·m −2 . Furthermore, the FG-SWE effectively treated high-salinity flowback fluid, reducing total dissolved solids content (TDS) from 8 × 10 4 mg L −1 to < 125 mg L −1 to meet drinking water standards. The evaporator also demonstrated excellent anti-fouling properties and long-term stability, retaining 90.7 % performance over 30 days of continuous operation. This study provides a promising technology for high-salinity wastewater, thereby supporting the green development of shale gas and enhanced recycling of water resources.
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Journal of Aquatic Food Product Technology
·
2026
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IF 1.2
Hanbing Xiao,Huijuan Wang,Can Zhao,Zhijie Zheng,Xiaoqiang He,Yingting Zhao,Yuting Tian
This study examined the effects of different impregnation methods and solutions on texture of soft-pack (retort) canned abalone. Results showed that room temperature and pressure immersion, with either pure water or sodium alginate, did not significantly affect abalone meat hardness. Ultrasonic immersion caused myofibril rupture, leading to a looser structure. Combining sodium alginate with ultrasonic immersion decreased hardness. Vacuum immersion utilized negative pressure to create larger voids, accelerating sodium alginate absorption and enhancing water retention, achieving tenderization without lipid oxidation. Overall, sodium alginate and vacuum impregnation proved most effective for improving abalone texture.
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Advanced Science
·
2026
·
IF 14.1
Xiaokai Li,Yonghui Zhang,Yongxin Li,Jiahao Zhang,Yuheng Li,Zhengyu Li,Jianwu Wang,Yaochen Lv,Yanan Wang,Jiyu Liu,Xin Liu,Huanxi Zheng
Underwater smart adhesives with switchable adhesion have attracted significant attention for applications in marine engineering and biomedical fields. However, achieving both robust adhesion and rapid on-demand detachment in aquatic environments remains a critical challenge. Inspired by the diving bell spider, we propose a design strategy based on heterogeneous wettability surfaces to achieve switchable adhesion between two surfaces. The heterogeneous wettability surface design confines the oil phase within air cavities formed in superhydrophobic (lipophilic) regions, thereby creating annular oil rings, which establish stable oil/water interfaces that spatially isolate the internal water bridge from the external aquatic environment. The Laplace pressure difference generated at the oil/water interfaces induces robust adhesion between surfaces. In addition, the adhesion strength can be linearly enhanced by constructing multiple, uniformly arranged oil/water interfaces. Rapid on-demand separation can also be achieved through controlled electrolysis of the internal water bridge by applying voltage between the surfaces. Finally, we demonstrate the practical applicability of this adhesive by integrating it into an unmanned underwater vehicle (UUV) for efficient underwater anchoring and ship-hull hitchhiking, highlighting its broad application potential in underwater engineering scenarios.
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CERAMICS INTERNATIONAL
·
2022
·
IF 5.532
Qikui Man,Xueheng Zhuang,Zhenkuang Lei,Shiqi Zhu,Lining Pan,Yu Gao,Guoguo Tan
For obtaining the ecofriendly microwave absorbing composites, flake carbonyl iron was mixed to the flotation carbon waste of titanium slag by ball-milling processes. The composites of 4 h ball-milling present excellent microwave absorbing performance of minimum reflected loss (RL) of −54.9 dB at 7.8 GHz with thickness of 2.6 mm. The same composites provide the performance of RL < −10 dB with the thickness from 1.2 mm to 5 mm at corresponding matching frequency from 3.3 GHz to 18 GHz. It means that the absorbing peak can be tunable at the wide frequency range with only adjusting the thickness. The strong absorbing intensity and wide tunable frequency range are attributed to the proper impedance matching of dielectric property from flotation carbon waste of titanium slag and magnetic property from carbonyl iron. Also, this work provides a research approach for handling industrial waste which contains carbon.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2022
·
IF 8.025
Yamei Wang,Dongdong Xiao,Hainan Yu,Yi Zhong,Linping Zhang,Xiaofeng Sui,Bijia Wang,Xueling Feng,Hong Xu,Zhiping Mao
The fabric-based wound dressings are hard to maintain a moist environment for wound healing while the hemostatic property and gas permeability of some hydrogel-based wound dressings are not ideal. This study first put forward a strategy of checkerboard-pattern wound dressing: 1) preparing the base fabric with hemostatic property, 2) printing multifunctional hydrogels onto one side of the base fabric to form checkerboard patterns, 3) modifying the other side of the base fabric to be hydrophobic. In this manner, the composite dressing not only maintained the advantages of hydrogels, but also inherited good mechanical property, hemostatic property, and gas permeability from the base fabric. Here, the cotton fabric was carboxymethylated to be MCF. To obtain multifunctional hydrogel, sodium carboxymethylcellulose was oxidated to introduce aldehyde groups to form Schiff base with amino groups in gelatin, besides, dopamine and Ag nanoparticles were introduced to endow the hydrogel with antioxidant property and antibacterial activity . The multifunctional hydrogel was printed onto one side of MCF, subsequently, the deposition of paraffin made the other side of this dressing become hydrophobic. The good performance of the obtained dressing in hemostatic process and wound healing demonstrated its potential in the field of wound treatment.
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JOURNAL OF LUMINESCENCE
·
2023
·
IF 3.6
Zhaofa Li,Quanxiu Zhou,Palanivel Sathishkumar,Liang Peng,Qunfang Wang,Feng Long Gu
The present work fabricated a novel dual-emission responsive ratiometric fluorescent hybrid nanoprobe using a mixture of blue fluorescence-emitting N-Doped Carbon Quantum Dots (N-CQDs) and red fluorescence-emitting l -cysteine-capped CdSe/ZnS Quantum Dots (Lcys-CdSe/ZnS QDs). The addition of Cu 2+ resulted in the strong and specific fluorescence quenching in Lcys-CdSe/ZnS QDs while N-CQDs retained their fluorescence intensity. Further exploration of the nanoprobe showed that the detection limit was 3.78 × 10 −9 M and the linear range was below 3.2 × 10 −6 M. The nanoprobe possessed excellent anti-interference in the Cu 2+ determination and its application was successful in natural water samples. Experimental results suggested that the superficial left cysteine (Lcys) combines with Cu 2+ causing static quenching. Results of density functional theory (DFT) computation explained that Cu 2+ has the greatest possibility to combine with surficial Lcys and furthermore illustrated the role of the combination in static quenching. The work showed one of origin of the selectivity of the nanoprobe and a potentially guidance to design high selective ratiometric fluorescent nanoprobes.
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COMPOSITES PART A-APPLIED SCIENCE AND MANUFACTURING
·
2023
·
IF 8.7
Junyu Lu,Haoruo Zhang,Mushan Yuan,Yunfei Gao,Mei Liang,Yang Chen,Huawei Zou
Without a reliable mechanical carrier, it is difficult to apply MA materials in realistic aerospace scenarios. Here, the broadband MA properties of RGO/melamine foam (RGO/MF) composites were prepared and optimized by hydrothermal chemical reduction method. The realization of broadband MA by RGO/MF is mainly achieved through the cooperative enhancement of RGO dispersion by the following two points: (1) three-dimensional (3D) meso -scale dispersion of RGO supplied by MF and (2) 3D microlayer separation of formed RGO provided by hydrothermal chemical reduction. For the first time, we successfully achieve complete filling of the RGO/MF into honeycomb. The RGO/MF honeycomb composites achieved almost 95.25 % EAB in the full frequency ranges from 2 to 18 GHz, where the MA performance of the composites originated from the electric-field loss of the RGO/MFs. Such RGO/MF honeycomb composites shows a promising application prospect and guidance in the field of aerospace stealth.
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