MATERIALS & DESIGN
·
2022
·
IF 9.417
Guoliang Jia,Zuhao Li,Hanxiang Le,Zhende Jiang,Yanan Sun,He Liu,Fei Chang
The accumulation of reactive oxygen species (ROS) in the oxidative stress microenvironment of diabetic wounds often results in delayed wound healing. In this study, a multifunctional hydrogel with ROS-scavenging property was developed by cross-linking epigallocatechin-3-gallate (EGCG), 2-(hydroxyethyl) methacrylamide (HEMAA), acrylamide (AM), and borax. The resulting hydrogel showed adequate hemostatic properties, self-healing capability, tissue adhesiveness, and an appropriate degradation rate. Moreover, the green tea derivative-based hydrogel scavenged the accumulated ROS and protected skin-related cells (such as keratinocytes, fibroblasts, and endothelial cells) from ROS-mediated death and proliferation inhibition. In vivo , this hydrogel accelerated diabetic wound healing by decreasing the ROS level, inducing macrophage polarization to the M2 phenotype, alleviating excessive inflammation, and promoting proliferation, epithelialization, collagen deposition, and neovascularization. By day 16, the hydrogel dressing had almost completely healed the diabetic wounds, whereas the residual wound areas of the blank control and the commercial Tegaderm TM dressing were 55.57 ± 5.67 % and 35.15 ± 3.45 %, respectively. Overall, this advanced hydrogel provides an effective strategy for the treatment of diabetic wounds and may be applied for the treatment of tissue injury in other ROS-accumulated microenvironments.
✓ 已验证
产品关联
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2023
·
IF 15.1
Chunlin Liu,Boxiang Zeng,Le Jiang,Yixian Wu,Yifan Wang,Jingyu Wang,Qiong Wu,Xiaodan Sun
Flexible supercapacitors based on hydrogel electrolytes are promising power sources for wearable devices but suffer from high interfacial resistance and other drawbacks. To address this problem, we herein prepared a tough poly(vinyl alcohol)-gelatine double-network hydrogel electrolyte and endowed it with self-healability and low interfacial resistance through the introduction of reversible boronic ester bonds, glycerol, and ammonium sulphate. The in situ deposition of a conductive polypyrrole layer on the hydrogel surface afforded an all-in-one supercapacitor with decreased electrode–electrolyte interfacial resistance. The performance of this supercapacitor (areal capacitance = 1325.5 mF cm −2 at a current density of 1 mA cm −2 , maximum energy density = 168.5 μW h cm −2 , maximum power density = 670 μW cm −2 ) was superior to that of most of integrated supercapacitors reported to date and was hardly affected by low temperatures, long-term storage, bending, or self-healing after damage. Moreover, a biocompatible strain sensor based on the above hydrogel was used to detect the motion of human (face, elbow, knee) and mouse (thigh) models and thus monitor their behaviour and activity levels. Thus, the multifunctional integration of our dual-network hydrogel was concluded to hold considerable promise for the fabrication of wearable devices.
✓ 已验证
产品关联
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2022
·
IF 16.744
Yingying Luo,Hongjiao Wu,Junpeng Qiao,Jiaming Zhang,Kai Liu,Liqing Zou,Ying Chen,Pengcheng Lin
It is still a big challenge to develop state-of-art thermal energy storage materials based on phase-change materials (PCMs) with superior thermophysical properties and wearability for efficient advanced personal thermal management (PTM). A novel strategy for synthesizing thermal energy storage gel with sandwich structure by confining the inorganic PCM gel in the organic PCM gel was proposed to maximize the advantages of inorganic PCMs, organic PCMs and gel materials. Octadecane and sodium sulfate decahydrate were selected as the organic PCM and inorganic PCM, respectively to satisfy the requirements of the working temperature of PTM. The thermal energy storage gels with sandwich structure demonstrate superior thermophysical properties, such as the absence of supercooling (0 °C), high latent heat (158.65 J g −1 ), high form-stability (no leakage), high cyclic stability (200 cycles) and high economic benefits (4.85 × 10 −3 ¥ J −1 ). Besides, they also have excellent wearability, such as high flexibility, self-healing feature and high biocompatibility. Due to the synergistic enhancement effect and various merits, the novel thermal energy storage gels are successfully utilized in the wearable PTM for human body thermal comfort. The inorganic–organic combination methodology is promising for the highly efficient applications of PCMs in the next-generation PTM.
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF MEMBRANE SCIENCE
·
2023
·
IF 9.5
Chuang Wang,Zhijie Guo,Chi Wang,Wei Liu,Xia Yang,Hongliang Huo,Yuhang Cai,Zhi Geng,Zhongmin Su
The inevitable membrane damage during the use of separation membrane seriously affects the separation and purification effects. Herein, we first synthesized a novel poly(aryl ether sulfone) material containing boronic acid groups (PES-H 2 BO 2 ) through molecular design, then PES-H 2 BO 2 ultrafiltration membrane was prepared via non-solvent induced phase inversion method. Further, the PES-H 2 BO 2 ultrafiltration membrane and polyvinyl alcohol (PVA) hydrogel were composited by hydrogen bonds and reversible boronate ester bonds between the two to fabricate a series of novel PVA hydrogel/PES-H 2 BO 2 composite ultrafiltration membranes. Through the ultrafiltration experiment of polyacrylamide (PAM) solution, the flux and retention rate changes of the composite ultrafiltration membrane in the initial stage, damage stage, self-healing stage, and stabilization stage were tested and analyzed. The results confirmed that the composite membrane has the ability to rapidly restore the flux and retention rate to the pre-breakage levels through a self-healing effect within 15 min after being damaged, demonstrating their outstanding self-healing characteristics. The design strategy of fabricating composite ultrafiltration membrane with excellent self-healing performance by forming hydrogen bond and reversible boronate ester bond between hydrogel and membrane matrix in this study provides a convenient and feasible way for the design and preparation of high-performance self-healing separation membranes.
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF NANOBIOTECHNOLOGY
·
2023
·Vol. 21
·期 1
·1-25
·
IF 10.2
Yan Haozhao,Hao Li,Chen Huayao,Zhou Xinhua,Ji Hongbing,Zhou Hongjun
Background There is a serious global problem of salinization of arable land, causing large reduction in world food production. Use of plant hormones is an effective way to reduce damage caused to crops and salt stress.Results In this study, PEI-EDA was modified with AM-zein and grafted with plant hormone SA (AM-zein-SA) and used as a nano-pesticide carrier to load emamectin benzoate (EB). The use of AM-zein-SA as a nano-pesticide carrier could reduce the damage caused by salt stress to crops. The structure of AM-zein-SA was characterized by FTIR, UV, fluorescence, Raman, and 1H NMR spectroscopic techniques. AM-zein-SA could effectively improve the resistance of EB to ultraviolet radiations, resistance of cucumber to salt stress, and the absorption of EB by plants. The experimental results showed that AM-zein-SA could effectively improve the anti-UV property of EB by 0.88 fold. When treated with 120 mmol NaCl, the germination rate of cucumber seeds under salt stress increased by 0.93 fold in presence of 6.25 mg/L carrier concentration. The POD and SOD activities increased by 0.50 and 1.21 fold, whereas the content of MDA decreased by 0.23 fold. In conclusion, AM-zein-SA nano-pesticide carrier could be used to improve the salt resistance of crops and the adhesion of pesticides to leaves.Conclusion AM-zein-SA, without undergoing any changes in its insecticidal activity, could simultaneously improve the salt stress resistance and salt stress germination rate of cucumber, reduce growth inhibition due to stress under high-concentration salt, and had a good effect on crops. In addition, EB@AM-zein-SA obviously improved the upward transmission rate of EB, as compared with EB. In this study, SA was grafted onto zein-based nano-pesticide carrier, which provided a green strategy to control plant diseases, insects, and pests while reducing salt stress on crops in saline-alkali soil.Graphical Abstract
✓ 已验证
产品关联
DOI
PubMed
高影响因子
LANGMUIR
·
2023
·
IF 3.9
Jiao Yan,Li Wang,Chunxia Zhao,Dong Xiang,Hui Li,Jingjuan Lai,Bin Wang,Zhenyu Li,Hongsheng Lu,Hongwei Zhou,Yuanpeng Wu
Wearable strain sensors of conductive hydrogels have very broad application prospects in electronic skins and human–machine interfaces. However, conductive hydrogels suffer from unstable signal transmission due to environmental humidity and inherent shortcomings of their materials. Herein, we introduce a novel moisture-proof conductive hydrogel with high toughness (2.89 MJ m–3), mechanical strength (1.00 MPa), and high moisture-proof sensing performance by using dopamine-functionalized gold nanoparticles as conductive fillers into carboxymethyl guar gum and acrylamide. Moreover, the hydrogel can realize real-time monitoring of major and subtle human movements with good sensitivity and repeatability. In addition, the hydrogel-assembled strain sensor exhibits stable sensing signals after being left for 1 h, and the relative resistance change rate under different strains (25–300%) shows no obvious noise signal up to 99% relative humidity. Notably, the wearable strain sensing is suitable for wearable sensor devices with high relative humidity.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
COMPOSITES SCIENCE AND TECHNOLOGY
·
2023
·
IF 9.1
Xiaodong Qi,Tingyu Zhu,Wenwen Hu,Wanjun Jiang,Jinghui Yang,Qing Lin,Yong Wang
Flexible and light/electrical responsive phase change materials (PCMs) provide significant application prospects in the thermal management and health monitoring of humans. However, the facile fabrication of flexible and multi-stimulus responsive PCMs remains a great challenge. Herein, we proposed a one-step photoinitiated polymerization strategy to prepare flexible phase change hydrogels, which were composed of hydrated salts (sodium sulfate decahydrate, SSD) and polyacrylamide (PAM) hydrogel and MXene nanosheets . The three-dimensional PAM/MXene network efficiently encapsulated the SSD, thus showing high dimension retention ratio of 98.1%, latent heat value of 163.3 J/g and excellent room-temperature flexibility. By triggering the melting-crystallization transition of SSD, the hydrogels showed tunable modulus variations and temperature sensitivity. Benefiting from the electrical MXene nanosheets and SSD crystals, these hydrogel-based sensors displayed good sensitivity (gauge factor of 3.36) with a large strain range (300%) and reliable durability (200 stretching cycles). More importantly, the PAM/SSD/MXene hydrogels exhibited remarkable solar-thermal energy conversion and storage performances due to the incorporation of MXene nanosheets, which could be applied in the photothermal therapy of human body at a constant temperature of ∼35 °C. These flexible phase change hydrogels with moderate phase transition temperatures as well as strain sensing and solar-thermal energy storage functions hold great application potential for wearable thermal management and healthcare devices.
✓ 已验证
产品关联
DOI
高影响因子
Advanced Healthcare Materials
·
2023
·Vol. 12
·期 13
·2203306
·
IF 10
Xinchang Kang,Pengfei Guan,Cairong Xiao,Can Liu,Youjun Guan,Yeying Lin,Yu Tian,Kunyu Ren,Yanting Huang,Rumin Fu,Chengyun Ning,Lei Fan,Guoxin Tan,Lei Zhou
Photothermal hydrogel adhesives have yielded promising results for wound closure and infected wound treatment in recent years. However, photothermal hydrogel bioadhesives with on-demand removability without additional nanomaterials-based photothermal agents have rarely been reported in the literature. In this work, an injectable intrinsic photothermal hydrogel bioadhesive with an on-demand removal trait is developed through dynamic cross-linking of gelatin (Gel), tannic acid (TA) quinone, and borax for closing skin incisions and accelerating methicillin-resistant Staphylococcus aureus (MRSA) infected wound healing. The TA quinone containing polyphenol and quinone groups with multifunctional adhesiveness and intrinsic photothermal performance confer the hydrogel adhesive with near-infrared (NIR) responsive antibacterial activity. The cross-linking of pH-sensitive boronic ester (polyphenol−B) and Schiff base bonds endow the hydrogel with great self-healing capacity and on-demand removability. Moreover, the hydrogel possesses good biocompatibility, injectability, and hemostasis. The in vivo experiment in a rat cutaneous incision model and full-thickness MRSA-infected wound model indicate that the smart hydrogel can close wounds efficiently and treat infected ones, demonstrating its superiority in noninvasive treatment of cutaneous incisions and enhancing infected full-thickness wound healing.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CHEMISTRY-A EUROPEAN JOURNAL
·
2023
·Vol. 29
·期 18
·e202203662
·
IF 4.3
Ziqian Yi,Shouqin Tian,Wei Geng,Tongkai Zhang,Wen Zhang,Yaoqi Huang,Hannah-Noa Barad,Ge Tian,Xiao-Yu Yang
Graphical Nanoncapsulation of E. coli by tannic acid (TA)-Fe complexes enhances its stability in seawater. Further, different types of nanomaterials can be easily introduced to the surface of E. coli using TA−Fe shells as a biological interface. The E. coli -based semiconductor biohybrid system prepared by nanoencapsulation and hybridisation can significantly enhance hydrogen production activity under illumination and shows good stability in seawater. CdS nanoparticles were introduced on E. coli cells to construct a hydrogen generating biohybrid system via the biointerface of tannic acid-Fe complex. This hybrid system promotes good biological activity in a high salinity environment. Under light illumination, the as-synthesized biohybrid system achieves a 32.44 % enhancement of hydrogen production in seawater through a synergistic effect.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
TRIBOLOGY LETTERS
·
2022
·Vol. 71
·期 1
·1-14
·
IF 3.327
Wu Jing,Yang Guangbin,Zhang Shengmao,Zhang Yujuan,Sun Lu,Sun Tianhua,Yu Laigui,Zhang Pingyu
Oleic acid-modified lanthanum borate nanosheets (OA-LBNs) were prepared by simple surface modification technology combined with precipitation method. The structure of the as-prepared light yellow transparent nanofluid of OA-LBNs was analyzed by Fourier transform infrared spectroscopy and transmission electron microscopy, and its thermal stability was evaluated by thermogravimetric analysis. Moreover, the tribological properties of OA-LBNs nanofluid as the lubricant additive in diisooctylsebacate (DIOS), poly-α-olefin (PAO4), and rapeseed oil (RO) were evaluated with a four-ball friction and wear tester, and its tribomechanisms in the three kinds of base oils were also discussed. The results show that OA-LBNs nanofluid exhibits good antiwear ability in the three kinds of base oils; in particularly, OA-LBNs nanofluid added in PAO4 shows the best antiwear ability. The tribological properties of the OA-LBNs nanofluid as the lubricant additive are dependent on the nature of the base oils. Namely, the polarity of the base oil influences the adsorption of the OA-LBNs nanofluid on the rubbed steel surface, thereby affecting the composition of the tribofilm formed on the rubbed steel surface and resulting in changes in tribological properties.
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF CHEMICAL RESEARCH
·
2022
·
IF 1.097
Shaoxiong Wu,Lianyuan Wang,Haiyan Zhu,Jing Liang,Liang Ge,Cong Li,Ting Miao,Jian Li,Zhenxing Cheng
Chemical warfare agents, such as nerve agents (GD and VX) and blister agents (HD), have strong toxicities to mankind. In recent years, zirconium-based metal-organic frameworks have been found to be attractive materials for chemical warfare agent degradation. Among them, metal-organic framework-808 (MOF-808) and porous coordination network-222 (PCN-222) were the best. However, few papers pay attention to their practical application. In this work, we prepared MOF-808 and PCN-222 using water phase and organic solvothermal methods, respectively. Their performance for the catalytic degradation of chemical warfare agents under practical decontamination conditions was studied. The results showed that MOF-808 displayed a high potency for catalytic hydrolysis of VX (10,000 mg L−1) in unbuffered solution. PCN-222 exhibited weaker reactivity with a half-life (t1/2) of 28.8 min. Their different performances might stem from the different connectivity of the Zr6 nodes and framework structures. The results illustrated that the hydrolysis of high-concentration GD required a strong alkaline buffer to neutralize the hydrolysis product of hydrofluoric acid (HF) to avoid catalyst poisoning. When H2O2 was used as the oxidant instead of O2, both zirconium-based metal-organic frameworks performed with effective catalytic potency for HD degradation without any special lighting and so was suitable for practical application, whereas the products obtained from HD, such as HDO2 and V-HDO2, still possessed vesicant toxicity. Overall, MOF-808 prepared via a water-phase synthesis performed with effective catalysis for the degradation of high-concentration VX, GD, and HD with t1/2 of < 0.5, 3.1 and 2.2 min, respectively, exhibiting its potential for practical applications.
✓ 已验证
产品关联
DOI
高影响因子
EUROPEAN POLYMER JOURNAL
·
2022
·
IF 5.546
Huan Li,Yingying Li,Yudan Wang,Lijia Liu,Hongxing Dong,Chunhong Zhang,Toshifumi Satoh
Flexible and self-healing conductive hydrogel, as a typical electronic skin with the function of transmitting sensory signals, has attracted remarkable attentions in the biomaterials field. However, the practical application of electronic skin has been severely limited owing to the potential bacterial infection threats. Here, in order to improve the antibacterial properties of electronic skin, a star-shaped polyetheramide (Tyr-PEAm) derived from L-tyrosine was synthesized and cross-linked into the hydrogel network. A compliant and self-healing conductive hydrogel (defined as PVA/PDA/Tyr-PEAm) was assembled from polyvinyl alcohol (PVA), polydopamine (PDA) and Tyr-PEAm. The hydrogel achieved a comprehensive performance of long-term antibacterial activity (the inhibition zones remained unchanged over 7 days), low hemolysis activity (hemolysis rate of 0.042 %), good conductivity and rapid self-healing ability (healing within 1 s). Therefore, the hydrogel could be used not only as a detection device to check normal skin, but also as the wound skin detection in real time. Furthermore, the good conductivity and rapid self-healing ability contributed to the hydrogel to detect various macro and micro movements of the human body, as well as to recycle as a new sensor. The PVA/PDA/Tyr-PEAm hydrogel that integrated intelligent signals and resisted bacterial infections exhibited broad application prospects in biomedical materials.
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）