SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2022
·
IF 4.831
Jialu Shen,Guoqing Chen,Zichen Yang,Yamin Wu,Chaoqun Ma,Lei Li,Taiqun Yang,Jiao Gu,Hui Gao,Chun Zhu
The accurate detection of fructose in human urine can help prevent and screen for diseases such as fructokinase deficiency and hereditary fructose intolerance. Surface-enhanced Raman spectroscopy (SERS) is an analytical technique with selectivity and high sensitivity, which has been widely applied to the detection of targets with complex backgrounds. In this work, 4-mercaptophenylboronic acid (4-MPBA) was modified on the surface of silver nanoparticles (AgNPs) under mild conditions to obtain a boronic acid-functionalized SERS substrate for the detection of fructose in artificial urine. The detection mechanism was based on the deboronization reaction of 4-MPBA on the surface of AgNPs, which was induced by fructose, and the Raman signal of the generated thiophenol (TP) molecules was significantly enhanced by the silver nanoparticles, with a linear increase in SERS peak intensity at 1570 cm −1 . We achieved the detection limits of 0.084 µmol/L in water and 0.535 µmol/L in urine by this method. The relative standard deviation (RSD) in the recovery experiments of urine ranged from 1.01 % to 2.22 %, and the whole detection time was less than 10 min, which indicated that this method is highly reliable for fructose detection and has a good prospect in bioassay and clinical medicine.
研究领域:
分析化学
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生物医学工程
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临床医学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
BIOELECTROCHEMISTRY
·
2023
·
IF 5
Zheng-Zhi Yin,Zixuan Liu,Min Zhou,Xu Yang,Guojun Zheng,Hongyu Zhang,Yong Kong
Sensitive detection of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) spike protein (S protein) is of significant clinical importance in the diagnosis of COVID-19 pandemic. In this work, a surface molecularly imprinted (SMI) electrochemical biosensor is fabricated for the detection of SARS-CoV-2 S protein. Cu 7 S 4 -Au is used as the built-in probe and modified on the surface of a screen-printed carbon electrode (SPCE). 4-Mercaptophenylboric acid (4-MPBA) is anchored to the surface of the Cu 7 S 4 -Au through Au–SH bonds, which can be used for the immobilization of the SARS-CoV-2 S protein template through boronate ester bonds. After that, 3-aminophenylboronic acid (3-APBA) is electropolymerized on the electrode surface and used as the molecularly imprinted polymers (MIPs). The SMI electrochemical biosensor is obtained after the elution of the SARS-CoV-2 S protein template with an acidic solution by the dissociation of the boronate ester bonds, which can be utilized for sensitive detection of the SARS-CoV-2 S protein. The developed SMI electrochemical biosensor displays high specificity, reproducibility and stability, which might be a potential and promising candidate for the clinical diagnosis of COVID-19.
研究领域:
生物医学工程
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分析化学
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分子生物学
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电化学
·
病毒学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF MOLECULAR STRUCTURE
·
2024
·
IF 4
Runqing Liu,Rongwei Shi,Jiming Huang,Fen Ye,Senlin Leng
Birefringent crystals are particularly important in optical communication and laser industries. Herein, we report the synthesis, structures, optical properties, and theoretical analyses of an oxyborate birefringence material CdInO(BO 3 ). It has an interesting sandwich-like basic building unit (BBU) constructed by [CdO 4 ] 6− chains and [InO 4 ] 5− chains. CdInO(BO 3 ) possesses an experimental band gap of 3.65 eV and an ultraviolet (UV) cut-off edge about 295 nm. Moreover, it exhibits a large birefringence (0.136@1064 nm), which mainly originates from the parallel arrangement of the isolated [BO 3 ] groups. This discovery indicates that CdInO(BO 3 ) can be a promising birefringent material.
研究领域:
材料科学
·
光学工程
✓ 已验证
产品关联
DOI
高影响因子
NEW JOURNAL OF CHEMISTRY
·
2021
·Vol. 45
·期 6
·2974-2980
·
IF 3.591
Zilong Chen,Junwei Feng,Bin Dai,Feng Yu
A new fluorooxoborate NaKB6O9F2 containing puckered layers has been synthesized using a high temperature solution method in a closed system. It is completely isostructural to NaRbB6O9F2. In their structure, the layers have two kinds of large empty holes composed of 16 element rings and super large rectangular rings. Through structural comparison, we found that the large empty holes in the layer and the introduction of the terminal F atoms may be the main reason for the formation of the structure containing puckered layers and the interlayer staggered arrangement tightly occluded together. Experimental and first-principles analyses were carried out to elucidate the optical properties.
研究领域:
无机化学
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材料科学
✓ 已验证
产品关联
DOI
高影响因子
ACS Applied Materials & Interfaces
·
2015
·
IF 6.723
Guilong Zhang,Shiyao Lu,Junchao Qian,Kai Zhong,Jianming Yao,Dongqing Cai,Zhiliang Cheng,Zhengyan Wu
We developed a highly efficient magnetic relaxation switch (MRS) system based on poly(vinyl alcohol) functionalized nanomagnetic iron oxide (PVA@NMIO) particles for the detection of boric acid or borate ester (BA/BE). It was found that the addition of BA/BE induced the aggregation of PVA@NMIO particles, resulting in a measurable change in the T2 relaxation time in magnetic resonance measurements. The main mechanism was proposed that the electron-deficient boron atoms of BA/BE caused the aggregation of PVA@NMIO particles through covalent binding to the hydroxyl groups of PVA. This novel detection system displayed excellent selectivity, high sensitivity, and rapid detection for BA/BE. Thus, this system may provide a great application prospect for detection of BA/BE.
研究领域:
分析化学
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材料科学
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医学检测
✓ 已验证
产品关联
DOI
PubMed
高影响因子
POLYHEDRON
·
2022
·
IF 2.975
Yan-Ling Deng,Wei Li,Chun-Yang Pan
Two new metal hybrid borates , Na[Ni(py) 2 ] 2 ·[(C 4 H 2 O 6 ) 2 B]·H 2 O (py = pyridine) ( 1 ) and [Cu(H 2 O) 2 (1-EI) 4 ]·[B 5 O 6 (OH) 4 ] 2 ·H 2 O (1-EI = 1-ethylimidazole) ( 2 ), have been successfully synthesized. 1 features an interesting structure based on mixed borate-tartrate motifs. Two tartrate anions are condensed with one BO 4 to form the hybrid anionic group [(C 4 H 2 O 6 ) 2 B] 5− . The structure of 2 is composed of [B 5 O 6 (OH) 4 ] − clusters and [Cu(H 2 O) 2 (1-EI) 4 ] 2+ complexes, which exhibits hydrogen-bonded network formed by [B 5 O 6 (OH) 4 ] − clusters. These compounds are further confirmed by FTIR, PXRD and UV–vis. In addition, the catalyst prepared from 2 shows excellent electrocatalytic oxygen reduction reaction (ORR) activity.
研究领域:
无机化学
·
电化学
✓ 已验证
产品关联
DOI
高影响因子
CHEMISTRY OF MATERIALS
·
2019
·
IF 10.159
Chongyi Liu,Wanwan Shen,Bonan Li,Tianfu Li,Hong Chang,Yiyun Cheng
Cytosolic protein delivery is of great importance for basic cell biology and the discovery of novel protein-based biotherapeutics. It remains a challenging task because of the limited binding sites on proteins and their relatively large size. As a result, most current approaches for cytosolic protein delivery need covalent modification on native proteins, which is usually involved with complicated synthesis, reduced protein bioactivity, and unexpected safety concerns. In this study, we proposed a novel strategy to deliver proteins of different molecular sizes and isoelectric points by specific recognitions between natural polyphenols and boronic acid-containing polymers. Protein molecules were decorated with polyphenols via noncovalent hydrogen-bond/hydrophobic interactions or reversible dynamic covalent bonds. The natural polyphenols increase the binding affinity between proteins and boronic acid-containing polymers, allow the release of bound proteins in acidic environments because of pH-sensitive property of catechol–boronate esters, and thus greatly promote the cytosolic delivery efficiency. This strategy showed robust efficiency in the delivery of various proteins such as bovine serum albumin, phycoerythrin, and ribonuclease A and maintained the protein bioactivity after intracellular release. The reported strategy permits the development of a polyphenol-involved polymer platform for cytosolic protein delivery.
研究领域:
生物技术
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药学
·
细胞生物学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF POWER SOURCES
·
2020
·
IF 8.247
Jianhui Li,Zaisheng Wang
Trimethyl borate (TMB) has been identified as electrolyte additive to suppress self-discharge for high voltage layered lithium-rich oxide cathode (LRO) for lithium ion batteries in our previous work. To expand pervious findings, its derivatives, triethyl borate (TEB) and tripropyl borate (TPB) with increased alkyl chains, have been considered as electrolyte additives to mitigate self-discharge behavior of LRO cathode for lithium ion batteries and we make a contrast to explain which one is better and why is better. It is found that fully charged (4.8 V, vs. Li/Li + ) LRO cathode suffers severe self-discharged issue upon storage in standard (STD) electrolyte (1 mol L −1 LiPF 6 -EC/EMC/DEC (3:5:2, in weight)). In contrast, this detrimental self-discharge behavior of LRO cathode at high voltage can be effectively depressed by introducing TEB or TPB into the electrolyte system. Combinations of electrochemical methods and multi spectroscopy techniques have been employed to evaluate effects of TEB and TPB on the LRO cathode surface . They reveal that the B–O and B–F bonds species in the film formed by TEB and TPB prevents electrolyte decomposition and protects LRO from structure transformation. These species in the film formed by TEB is much more than TPB, which explains the better effect for TEB.
研究领域:
材料科学
·
电化学
✓ 已验证
DOI
高影响因子
TALANTA
·
2020
·
IF 5.339
Ning Xia,Daohong Wu,Haiqing Yu,Wanwan Sun,Xinyao Yi,Lin Liu
Simple, sensitive and rapid detection of circulating tumor cells (CTCs) is of great importance for early diagnosis and therapy of cancers. Overexpression of sugar units on cell surface is related to the phenotypes of many cancers. Based on the boronate ester interaction, we reported the electrochemical and colorimetric detection of CTCs with high simplicity and sensitivity. Specifically, ferroceneboronic acid (FcBA) can be measured by differential pulse voltammetry and 4-mercaptophenylboronic acid (MPBA) can induce the aggregation and color change of gold nanoparticles (AuNPs). CTCs captured by the aptamer-modified magnetic beads (Apt-MBs) can sequestrate FcBA or MPBA molecules by the formation of boronate ester bonds, thus leading to the decrease in the electrochemical signal of FcBA or preventing the MPBA-triggered aggregation of AuNPs. Due to the overexpression of sugar groups on the surface of CTCs, the amplification-free methods exhibited high sensitivity and obviated the use of additional antibody or aptamer for the recognition of captured cells. With MCF-7 cancer cell as the model, 50 cells can be readily determined by the electrochemical and colorimetric methods. The proposed strategy is valuable for probing of cell glycosylation and designing of novel sensing devices for detection of sugar-containing biological macromolecules and cells.
研究领域:
生物化学
·
分析化学
·
癌症研究
·
分子生物学
✓ 已验证
DOI
PubMed
高影响因子
ADVANCED MATERIALS
·
2024
·
IF 27.4
Lei Wang,Xuerong Ding,Yiheng Hu,Qiurui Li,Yibing Bian,Yefan Duan,Shujie Lu,Hongbin Han,Ning Gu,Jianfei Sun
Topology, the study of properties that are invariant under continuous transformations, in which the number of pores (genus) is a profound concept that determines a number of properties that have been verified in many microscopic systems, but have not been studied in macroscopic materials. Microgels are widely used materials, and based on microfluidics, regular, stable, and reproducible microgels can be prepared, but studies from the perspective of topological principles have not been reported. In this paper, a system based on a boric acid ester rapid cross-linking strategy that can rapidly capture topological changes during the transient process of droplet-to-ring transition is proposed. The electrical dissipation properties associated with different transient topologies during the process are also investigated, demonstrating that the change of topological structures in macroscopic materials also affected their electrical properties, laying the foundation for the design of modulated macroscopic micro structured materials based on topology theory.
研究领域:
材料科学
·
物理学
·
化学工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ACS Omega
·
2019
·
IF 2.584
Simin Cui,Xianglei He,Dan Wang,Jie-Xin Wang,Yuan Pu,Jian-Feng Chen
The ideal product of rare-earth-doped phosphors should have uniform particle size distribution and homogeneous doping ions in each particle, and therefore, intensified micromixing at mesoscale is highly required. In this article, inspired by the concept of “mesoscience”, we demonstrate the tuning of Eu3+ doping in GdBO3 microparticles at mesoscale by a high-gravity-assisted reactive precipitation-coupled calcination process. The high-gravity environment and tiny droplets generated by the high-gravity rotating packed bed (RPB) reactor lead to significant intensification of mass transfer and micromixing, which are beneficial for the homogeneous doping of Eu3+ in the host material during reactive precipitation in liquid solution. Under excitation at 395 nm, the emission spectra of the Eu3+-doped phosphors exhibit a narrow-band red emission centered at 625 nm and the highest intensity was observed at x = 0.2. The RPB products show higher intensity than that of the control group even when the reaction time was shortened to 1/6. After calculation, the quenching in the sample most likely results from dipole–dipole interactions. The chromaticity coordinates for the RPB sample was measured as (0.598, 0.341) with a quantum yield of up to 78.11%, and the phosphors exhibit good thermal stability at 423 K. The phosphors were used as the luminescent materials for light-emitting diodes (LEDs), and the devices showed good performance. Our preliminary study illustrated that high-gravity-assisted approaches are promising for tuning the doping of rare-earth ions in microparticles at mesoscale toward efficient production of phosphors for LEDs.
研究领域:
材料科学
·
发光材料
·
纳米技术
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF POWER SOURCES
·
2020
·
IF 8.247
Dongmei Zhuang,Xianli Huang,Zhihui Chen,Hao Gong,Lei Sheng,Li Song,Tao Wang,Jianping He
Lithium dendrite growth has long been regarded as the main obstacle for the practical usage of lithium metal battery . In this paper, we heat-treat the copper collector at a low temperature to prepare a Cu x O (x = 1–2)/Cu composite electrode. The samples heat-treated at 250 °C are mainly composed of Cu 2 O confirmed by X-ray photoelectron spectroscopy (XPS) analysis, which has the best wettability with propylene carbonate (PC)-based electrolyte. The as-prepared Li–Cu cell (composite electrode) can run more than 150 cycles. However, boric acid additive can prolong the cycle number of Li–Cu cell to more than 300 cycles at a current density of 0.5 mA cm −2 with a Coulombic efficiency larger than 85%. Scanning electron microscopy (SEM) image shows that the Cu 2 O/Cu composite electrode with boric acid additive in the electrolyte can inhibit the formation of lithium dendrite on the surface of the electrode, and a uniform and dense nano-columnar lithium layer can be obtained even at 5 mA cm −2 . The synergistic effect is attributed to the improved interfacial properties for Cu 2 O/Cu composite collectors when boric acid (BA) is used as additives.
研究领域:
材料科学
·
电化学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）