Journal of Cleaner Production
·
2024
·
IF 9.7
Chengling Huang,Youjie Gao,Yi Chen,Yunfei Shen,Hou-Yong Yu
Earth has become depleted of oil and has suffered from the misuse of non-biodegradable plastics. Significant efforts have been dedicated to addressing the application flaws of cellulose as a substitute for plastics derived from petroleum. One of key defects was non-hydrophobic nature which highly influenced the mechanical properties of cellulose material during practical uses. Here, an innovative method was proposed to achieve hydrophobic modification of cellulose films through the molecular dissociation of dodecyltrimethoxysilane (DTMS) without the use of any toxic agents during the cellulose regeneration process. The hydrophobic (water contact angle of 118°), transparent (transmittance of 85%), and high-strength (70 MPa) DC films (cellulose films modified by DTMS) were successfully fabricated via cellulose regeneration process tailored by DTMS after molecular dissociation. The DC films stood out in both hydrophobicity and strength compared with several commercial plastics and the possible hydrophobic mechanism was proposed. Furthermore, the obsession with smart sensing abilities in DC films has made it a potential tool for monitoring baby diapers. Therefore, unlike conventional concepts, the methodology we adopted is simple and efficient, and it also eliminates the need for cellulose and replaces it with plastics.
研究领域:
材料科学
·
化学工程
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产品关联
DOI
高影响因子
RSC Advances
·
2016
·Vol. 6
·期 26
·21362-21366
·
IF 3.289
Yu-Peng Liu,Hui-Fen Liu,Yan-Ge Feng,Zhi-Lu Liu,Hai-Yuan Hu,Bo Yu,Feng Zhou,Qun-Ji Xue
Transparent superhydrophobic coatings for the protection of material surfaces are becoming more and more important along with the rapid development of intelligent electronic displays. Here we present an easily fabricated, transparent and healable superhydrophobic self-cleaning coating. The polyaniline nanofiber network is coated with a silica shell by chemical vapor deposition of tetraethoxysilane catalyzed by ammonia. A porous silica nanotubular coating is obtained after calcination. By releasing perfluorooctyl acid packed in the pores of nanotubes at mild conditions, healable self-cleaning performance of the coating is achieved. The coating has high transparency for reading letters and pictures beneath the coated glass plate.
研究领域:
材料科学
·
化学工程
✓ 已验证
DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2025
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IF 8.5
Haofeng Qiu,Xufeng Mao,Gaoke Pan,Ximing Cai,Xin Zhao,Xiang Wu,Lei Shao,Haijiao Mao,Dangsheng Xiong,Rong Wang
Post-traumatic osteoarthritis remains a significant clinical challenge, with limited effective treatment options. Conventional hydrogels for articular cartilage repair primarily focus on the bioactivity of the materials but often overlook the importance of monitoring the hydrogel's behavior in situ . This study presents the development of a novel injectable, traceable fluorescent hydrogel designed to prevent cartilage degradation and promote cartilage regeneration. The hydrogel was synthesized by forming a dynamically crosslinked network of oxidized hyaluronic acid (OHA) and adipic dihydrazide-grafted HA (HA-ADH), followed by photo-crosslinking with methacrylated gelatin (GelMA). Furthermore, GelMA was covalently conjugated with Rhodamine B, enabling real-time tracking of hydrogel degradation in situ . Experimental results demonstrated that the fluorescence of the hydrogel could effectively penetrate both skin and cartilage tissues, allowing for real-time monitoring. Additionally, the hydrogel exhibited superior lubrication (with a coefficient of friction of 0.134, comparable to HA) and favorable rheological properties, along with excellent biocompatibility. It also promoted cell differentiation and migration. In vivo studies showed that the hydrogel facilitated cartilage repair and prevented cartilage degradation over a 56-day period. Given its mechanical properties, biocompatibility, and fluorescence-based monitoring capability, this hydrogel shows great promise for real-time tracking in cartilage repair for the treatment of post-traumatic osteoarthritis.
研究领域:
生物材料学
·
再生医学
·
骨科
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产品关联
DOI
PubMed
高影响因子
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
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2023
·
IF 4.6
Xiaohui Tang,Munire Kurban,Ipargul Hafiz,Qi Shen,Mei Wang
Aims To prepare hyaluronic acid-loaded Harmine polymeric micelles with CD 44 targeting properties and to investigate their anti-breast cancer effects in vitro . Methods The carboxyl group on hyaluronic acid is coupled to the amino group on 3,5-bis(trifluoromethyl)benzylamine by an amidation reaction. And the polymeric micelles self-assemble to encapsulate the Harmine in a hydrophobic core, characterized the polymer micelles by IR, 19 F-NMR, Malvern particle sizing, release, hemolysis, and other experiments. Used CD 44 -positive MDA-MB-231 cells and CD 44 -negative MCF-7 cells as tumor models. The effect of polymer micelles on breast cancer cells in vitro by cytotoxicity assay, confocal, and flow cytometry. Results The prepared polymer micelles had a uniform particle size of about 200 nm, good dispersion, PDI < 0.3, encapsulation rate up to 87%, drug loading of 4.12±0.03%, and negative charge. Hyaluronidase has a good enzymatic effect on polymeric micelles, with a hemolysis rate of less than 1%. It showed some dose-dependent toxicity to both MDA-MB-231 and MCF-7, with increased uptake of polymer micelles by CD 44 -positive MDA-MB-231 compared to CD 44 -negative MCF-7 cells and significant effects of polymer micelles on apoptosis and cycling in both cell types. These results suggest that the hyaluronic acid-loaded Harmine polymer micelles designed in this study are effective in killing breast cancer cells while at the same time reducing the toxicity of Harmine and improving its slow-release targeting.
研究领域:
药剂学
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肿瘤学
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产品关联
DOI
PubMed
高影响因子
RSC Advances
·
2015
·Vol. 5
·期 90
·74126-74131
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IF 3.84
Jun Zhu,Xiufang Xu,Jinglei Liu,Yiqun Zheng,Shifeng Hou
We report a facile method for the synthesis of oleylamine-capped silver (Ag) nanowires in high purity. For the first time, Ag nanowires could be produced in high purity via a simple one-pot approach in a hydrophobic phase. The success of this synthesis relies on the use of Cu2+ to mediate the reduction of silver bromide (AgBr) by oleylamine at an elevated temperature, which promoted the high-yield formation of Ag products with a wire-like shape. These Ag nanowires were washed and deposited on PET films to form a transparent conductive electrode (TCE), which showed a sheet resistance of 34.0 Ω sq−1 and an optical transmittance of 70–80% at visible wavelengths. In addition to TCEs, these nanowires could also find important applications in the fields of conductive ink, and wearable electronics, among others.
研究领域:
材料科学
·
纳米技术
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产品关联
DOI
高影响因子
POLYMERS FOR ADVANCED TECHNOLOGIES
·
2018
·Vol. 29
·期 6
·1788-1794
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IF 2.137
Si Chen,Bo Zhou,Meng Ma,Yanqin Shi,Xu Wang
Permanently antistatic and high transparent PMMA terpolymer, P(MMA-co-HPA-co-SPMA), were reported in this paper, providing a new method to significantly improve the antistatic properties of PMMA without sacrificing transparency. 2-Hydroxypropyl acrylate (HPA) was chosen as a kind of compatilizer because of the good compatibility with both methyl methacrylate (MMA) and sulfopropyl methacrylate potassium salt (SPMA), a potential antistatic agent with a strong hydrophilic group. The mechanical and optical properties of P(MMA-co-HPA-co-SPMA) terpolymer barely show any visibly differences compared to PMMA homopolymer, confirmed through Fourier transform infrared, dynamic mechanical analysis, and a haze meter. Furthermore, antistatic property analysis indicates that only a small amount of SPMA can significantly improve the antistatic properties of the obtained PMMA terpolymers. The surface resistivity of the P(MMA-co-HPA-co-SPMA) sheets could be reduced to 10 9 Ω sq −1 order of magnitude, while the SPMA content reached 0.72 wt%. The hydrophilic groups, the hydroxyl and acrylate sulfonate, on the surface contributed to attract the water molecules, which rendered it a reasonably good antistatic property. These selected terpolymers will provide more opportunities to develop high-performance and antistatic products made from PMMA materials.
研究领域:
材料科学
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高分子化学
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产品关联
DOI
高影响因子
INFRARED PHYSICS & TECHNOLOGY
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2021
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IF 2.638
Yuxin Pan,Hui Lin,Ruijin Hong,Dawei Zhang,Haojie Sun
A series of Yb 3+ , Ho 3+ , Ce 3+ :YAG ceramics have been sintered at 1780 °C by high temperature solid state reaction under oxygen atmosphere. The absorption spectra , fluorescence spectra and fluorescence decay curve were discussed. The Judd-Ofelt (J-O) theory was applied to obtain the values of Ω 2 = 13.95 × 10 −20 cm 2 , Ω 4 = 3.94 × 10 −20 cm 2 and Ω 6 = 0.87 × 10 −20 cm 2 , respectively. After doping the Ce 3+ ions, the σ em of Yb 3+ , Ho 3+ , Ce 3+ :YAG ceramic at 2094 nm increased from 5.67 × 10 −20 cm 2 to 7.26 × 10 −20 cm 2 . These results demonstrate that Yb 3+ , Ho 3+ , Ce 3+ :YAG ceramic could be promising for 2 μm region.
研究领域:
材料科学
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光学
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产品关联
DOI
高影响因子
Journal of Biomedical Nanotechnology
·
2023
·Vol. 19
·期 12
·2045-2059
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IF 2.9
Yang Bowen,Huang Luyao,Zhou Zishuo,Yin Shanmei,Xi Mingrong
We aimed to develop an ovarian cancer-directed drug delivery system based on the high affinity of hyaluronic acid for CD44. The effects and mechanisms of hyaluronic acid-containing nanoparticles were investigated. The expression of CD44 in ovarian cancer was also determined. Hyaluronic
acid polymerized nanoparticles (HANPs), FITC-HANPs, and paclitaxel (PTX)-HANPs were prepared, and their characteristics were evaluated. The in vitro targetability and cytotoxicity properties of PTX-HANPs were evaluated through in vitro drug uptake and cytotoxicity assays. The
mechanisms of PTX-HANPs activity were investigated by apoptosis, wound healing, and Transwell invasion assays. In vivo targeting properties of HANPs were observed using a mouse ID8 subcutaneous model. in vitro experiments revealed an improved uptake of FITC-HANPs. The cytotoxicity
of PTX-HANPs in A2780/CP70 and ID8 cells was higher than that of PTX alone. PTX-HANPs increased cell apoptosis in a dose-dependent manner and exhibited a similar ability as PTX to inhibit cell migration. Furthermore, HANPs did not promote A2780/CP70 or ID8 cell migration and showed limited
inhibitory effects on their invasion. In vivo drug tracing experiments demonstrated the targetability of FITC-HANPs. In conclusion, PTX-HANPs improved PTX targetability and exhibited potent tumor-specific therapeutic activities. It may be considered a promising formulation for the preclinical
development of agents targeting epithelial ovarian cancer.
研究领域:
药剂学
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肿瘤学
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生物医学工程
✓ 已验证
DOI
高影响因子
JOURNAL OF THE EUROPEAN CERAMIC SOCIETY
·
2021
·
IF 5.302
Zixin Wang,Hui Lin,Dawei Zhang,Ruijin Hong,Yanna Tian,Jie Chen,Shengming Zhou
In this paper, Ba 0.75 Al 11 O 17.25 was selected as the host for the Eu 2+ and Mn 2+ co-dopants due to the Reidinger defects in its lattice. Upon the 365 nm excitation, the phosphors presented the cyan to green tunable emission by changing the doping concentration of Mn 2+ . Moreover, this phosphor possesses zero-thermal quenching up to 448 K due to the interaction between the traps and Eu 2+ /Mn 2+ . The completely densified ceramic guaranteed the high optical transmittance (∼72 % at 516 nm) and thermal conductivity (4.3 W·m −1 ·K −1 at room temperature). When combined with a 6 W commercial 365 nm emitting LED chip, the temperature of the ceramic eventually stabilized at 428 K and the luminous efficacy of the LED device was almost not influenced by the thermal quenching effect. This work may open a way for exploring new phosphor conversion materials for HP/HB PC solid state lighting.
研究领域:
材料科学
·
光学工程
✓ 已验证
DOI
高影响因子
Materials Today Chemistry
·
2025
·
IF 6.7
Zicheng Yuan,Xiaoqin Zhang,Fei Liu,Xianliang Jiang,Hao Wang,Jin Zhu,Jinggang Wang
High glass transition temperature polymers are extensively used in many fields such as packaging, electronic products, and automobiles. However, most of them are expensive as synthesized in polar aprotic solvent with low solid percent. The task of effectively synthesizing high glass transition temperature polymers faces at least three important challenges: the need for a solvent-free process to reduce cost and pollution, the requirement for a thermoplastic process with a high glass transition temperature above 150 °C, and the use of monomers derived from renewable resources. Traditional polyesters can be prepared via melt polycondensation, but achieving a glass transition temperature above 130 °C while maintaining good mechanical properties remains challenging. In this work, we developed a strategy to synthesize a new high glass transition temperature polyesters by employing rigid bulky diol of 9,9-bis [6-(2-hydroxyethoxy)naphthyl]fluorene (BNEF) and bio-based 2,5-furandicarboxylic acid (FDCA) which derived from fructose or furfural, as the main monomers. The new copolyesters exhibit a glass transition temperature of up to 164.2 °C, a number-average molecular weight of 24,600 g/mol, along with tensile modulus and strength values of 3030 MPa and 134 MPa, respectively. Furthermore, the copolyesters exhibit excellent transparency properties of 88.4 % by cutoff at 700 nm and well solvent resistance, which could serve as new low-cost, high-performance engineering plastics with ultra-high glass transition temperature and transparency.
研究领域:
材料科学
·
聚合物化学
✓ 已验证
产品关联
DOI
高影响因子
EUROPEAN POLYMER JOURNAL
·
2024
·
IF 5.8
Linxuan Han,Fenghao Hao,Yajun Chen,Xiao Wu,Lijun Qian
In this study, a novel phosphorus-containing flame retardant, SMAE, was prepared through a nucleophilic addition of N,N'-bis(salicylidene)ethylenediamine (SAED) and phenyl hypophosphite. SMAE can dissolve well in epoxy resin and provides molecular-level flame retardancy. By using SMAE as a co-curing agent and DDM to cure epoxy resin, EP/SMAE composites with excellent flame retardancy and good mechanical properties were obtained. As the dosage gradually increases, the limited oxygen index (LOI) values continue to rise. At a 5 % dosage, the Limiting Oxygen Index (LOI) value can reach 39.7 % and meet the UL 94 V-0 standard. It is observed that SMAE mainly exerts a blowing-out effect in EP. In addition, the use of SMAE as a co-curing agent can improve the impact strength of EP. The impact strength of 5 % SMAE/EP can reach 14.15 kJ/m 2 , which is 25 % higher than that of pure EP.
研究领域:
材料科学
·
化学工程
✓ 已验证
产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2024
·
IF 7.7
Yawen Zhao,Mingyu Li,Nuoya Chen,Kaiyang Huang,Xiaofeng Wu,Yanfei Tan,Qinsheng Hu,Rifang Luo,Yunbing Wang
Ensuring excellent anticoagulant, anti-inflammatory, and endothelialization properties in vascular stents through coating construction is crucial for their satisfactory performance post-implantation. In this study, we propose a cell-membrane mimetic multifunctional hyaluronic acid (HA)-based coating by combining the aminolyzed methacryloyloxyethyl phosphorylcholine (MPC) copolymer with oxidized hyaluronic acid (Ox-HA) through Schiff base reaction. Compared with traditional anti-fouling design, the composite coating present a stage-specific ability, which can resist the adhesion of blood components, while mediating vascular cell fate with the incorporation of HA. The coating exhibited promoted endothelial cell (EC) growth and inhibited the proliferation of smooth muscle cells (SMCs) by inducing a phenotype change. Besides, the multifunctional HA-based coating can mediate macrophages to a M2 phenotype. The coated stents were implanted in rabbits, and exhibited ideal capabilities in promoting endothelialization and inhibiting inflammation and restenosis in vivo , offering a potential approach to address multifunctionality for vascular implants.
研究领域:
生物医学工程
·
心血管医学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
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