Microbiome
·
2017
·Vol. 5
·期 1
·1-18
·
IF 8.496
Hill Cian J.,Lynch Denise B.,Murphy Kiera,Ulaszewska Marynka,Jeffery Ian B.,O’Shea Carol Anne,Watkins Claire,Dempsey Eugene,Mattivi Fulvio,Tuohy Kieran,Ross R. Paul,Ryan C. Anthony,O’ Toole Paul W.,Stanton Catherine
Background The gut is the most extensively studied niche of the human microbiome. The aim of this study was to characterise the initial gut microbiota development of a cohort of breastfed infants ( n = 192) from 1 to 24 weeks of age. Methods V4-V5 region 16S rRNA amplicon Illumina sequencing and, in parallel, bacteriological culture. The metabolomic profile of infant urine at 4 weeks of age was also examined by LC-MS. Results Full-term (FT), spontaneous vaginally delivered (SVD) infants’ microbiota remained stable at both phylum and genus levels during the 24-week period examined. FT Caesarean section (CS) infants displayed an increased faecal abundance of Firmicutes ( p < 0.01) and lower abundance of Actinobacteria ( p < 0.001) after the first week of life compared to FT-SVD infants. FT-CS infants gradually progressed to harbouring a microbiota closely resembling FT-SVD (which remained stable) by week 8 of life, which was maintained at week 24. The gut microbiota of preterm (PT) infants displayed a significantly greater abundance of Proteobacteria compared to FT infants ( p < 0.001) at week 1. Metabolomic analysis of urine at week 4 indicated PT-CS infants have a functionally different metabolite profile than FT (both CS and SVD) infants. Co-inertia analysis showed co-variation between the urine metabolome and the faecal microbiota of the infants. Tryptophan and tyrosine metabolic pathways, as well as fatty acid and bile acid metabolism, were found to be affected by delivery mode and gestational age. Conclusions These findings confirm that mode of delivery and gestational age both have significant effects on early neonatal microbiota composition. There is also a significant difference between the metabolite profile of FT and PT infants. Prolonged breastfeeding was shown to have a significant effect on the microbiota composition of FT-CS infants at 24 weeks of age, but interestingly not on that of FT-SVD infants. Twins had more similar microbiota to one another than between two random infants, reflecting the influence of similarities in both host genetics and the environment on the microbiota.
研究领域:
微生物学
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儿科
·
分子生物学
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DOI
PubMed
高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2025
·
IF 9.7
Feifei Pei,Jiqing Lu,Lin Li,Jie Yan,Tian Bai,Haijiao Yu,Dong Wang,Guangping Han,Wanli Cheng
Sorption-based atmospheric water harvesting (SAWH) offers a promising solution to address freshwater scarcity. Although many solid sorbents exhibit high water uptake capacities, their ability to achieve continuous, all-day water production still depends on complex system configurations. Here, a 24-h SAWH system is presented, enabled by wood-based ionogel (WIG) with simultaneous sorption-desorption functionality. The WIG is prepared by encapsulating 1-ethyl-3-methylimidazolium acetate ([EMIM][Ac]) into the natural wood channels, functioning as a sorption module. Meanwhile, carbonized wood, with photothermal and Joule heating properties, serves as the desorption module. Adjusting the sorption/desorption area ratio enables dynamic kinetic balance, allowing simultaneous moisture uptake and release within a single ionogel. The WIG leverages the water transport capability of wood channels and the fluidity of [EMIM][Ac] to shorten the sorption equilibrium time to 3 h and sustain directional water transfer from the sorption to the desorption zone. This system, driven by solar heating during the day and Joule heating at night, achieves 24-h continuous water production, yielding 47.62 g water per day under natural conditions, equivalent to 2.38 L water m solar − 2 day − 1 ( L water m solar − 2 day − 1 , defined as liters of water produced per solar absorbing area per day). This work demonstrates a sustainable and efficient SAWH strategy, highlighting the unique advantages of wood and offering a new avenue toward mitigating the global water crisis.
研究领域:
环境科学
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材料科学
·
水资源管理
·
能源工程
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化学工程
·
可持续技术
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产品关联
DOI
PubMed
高影响因子
Human Vaccines & Immunotherapeutics
·
2024
·
IF 4.1
Xiande Huang,Ziqi Cheng,Yake Lv,Weixuan Li,Xiaoyu Liu,Weijin Huang,Chenyan Zhao
Seasonal influenza is a severe disease that significantly impacts public health, causing millions of infections and hundreds of thousands of deaths each year. Seasonal influenza viruses, particularly the H3N2 subtype, exhibit high antigenic variability, often leading to mismatch between vaccine strains and circulating strains. Therefore, rapidly assessing the alignment between existing seasonal influenza vaccine and circulating strains is crucial for enhancing vaccine efficacy. This study, based on a pseudovirus platform, evaluated the match between current influenza H3N2 vaccine strains and circulating strains through cross-neutralization assays using clinical human immune sera against globally circulating influenza virus strains. The research results show that although mutations are present in the circulating strains, the current H3N2 vaccine strain still imparting effective protection, providing a scientific basis for encouraging influenza vaccination. This research methodology can be sustainably applied for the neutralization potency assessment of subsequent circulating strains, establishing a persistent methodological framework.
研究领域:
病毒学
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流行病学
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公共卫生
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DOI
高影响因子
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
·
2015
·
IF 2.495
Chao Xu,Yong Chen,Heng-Yi Zhang,Yu Liu
A crown ether-based supramolecular gel with a three-dimensional network structure was successfully constructed via a hierarchical induced assembly strategy and characterized by UV/vis NMR, viscometry and DLS. Therein, the coordination linkage of bis(terpyridyl)dibenzo-24-crown-8 1 with Zn 2+ produces the 1 /Zn 2+ supramolecular polymer as the primary assembly. Then, the anthryl-dibenzylammonium guest 2 was grafted to the 1 /Zn 2+ supramolecular polymer via the non-covalent association of dibenzylammonium moieties on guests with the dibenzo-24-crown-8 rings on supramolecular polymer. Furthermore, the supramolecular polymer with anthryl grafts underwent a photo-induced secondary assembly to produce the supramolecular gel, which could be reversibly disassembled by a thermo-induced dissociation of anthracene dimers. These photo/thermo-induced hierarchical assembly/disassembly behaviors will provide a potential way to construct degradable hierarchical supramolecular assemblies employing environment-friendly external stimuli, such as light and heat, as controlling method.
研究领域:
化学
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材料科学
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产品关联
DOI
高影响因子
NANOTECHNOLOGY
·
2021
·Vol. 33
·期 2
·025501
·
IF 3.874
Ruyan Xie,Nannan Zhang,Yaoyao Qu,Mingyu Tang,Fang Zhang,Fang Chai,Zhongmin Su
Herein, we have reported a facile one-pot strategy to synthesize fluorescent Cu nanclusters (Cu NCs) by using ʟ-histidine as stabilizer, and ascorbic acid as reducing agent. Cu NCs are stable, water-dispersible, and emit bright cyan emission with a quantum yield 26.08%. The Cu NCs can be employed as colorimetric and fluorimetric dual-mode detector, exhibiting excellent selectivity and sensitivity for detecting 2,4-dinitrophenol (DNP) specifically. Notably, Cu NCs were a sensitive sensor, which had speciality to detect DNP in range of linearity from 0.01 to 0.15 mM with a discernable limit as low as 3.96 μM. The mechanism of efficiently selective detection of DNP by Cu NCs was analyzed by UV absorption, fluorescence decay spectrum, and the performance of 'turn off' towards DNP was determined as the inner filter effect and static quenching effect. Further, the environmental tolerance of the Cu NCs probe was estimated by using the different natural water samples, demonstrating its great promise in the field of DNP monitoring and water sample analysis.
研究领域:
分析化学
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环境科学
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纳米技术
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DOI
高影响因子
JOURNAL OF HAZARDOUS MATERIALS
·
2019
·
IF 7.65
Qihui Zhang,Dan He,Xinran Li,Wei Feng,Cong Lyu,Yifeng Zhang
Peroxymonosulfate (PMS) has gained attention as oxidant for SR-AOPs. It is essential to develop a stable heterogeneous catalyst with strong hydrophilicity and high electron transfer capability for PMS activating. In this study, cobalt oxyhydroxide (CoOOH) was synthesized and activated PMS for degradation of 2,4-dichlorophenol (2,4-DCP) aiming to assess the feasibility of CoOOH/PMS system. 50 mg/L of 2,4-DCP could be 100% degraded within 120 min with 0.20 g/L CoOOH and 6 mM PMS. CoOOH/PMS system possessed a high degradation efficiency (0.0462 min −1 ), which was about 10 and 4 times higher than Co 3 O 4 /PMS and CoFe 2 O 4 /PMS system, respectively. Furthermore, it was found that CoOOH/PMS system displayed effective catalytic performance over broad pH range (e.g. 3–9). Importantly, the quenching tests revealed that 1 O 2 was identified as dominant reactive oxygen species (ROS). Co (Ⅲ) was rapidly reduced to Co (Ⅱ) owing to the efficient electron transfer rate performance of CoOOH in the catalytic reaction. Then, the regeneration of Co (Ⅱ) facilitated CoOH + owing to the surface of CoOOH with sufficient hydroxyl group, which is crucial for PMS activation and reactive oxygen species-ROS generation. This study proposed an alternative technology based on peroxymonosulfate catalyzed by cobalt-based hydroxide for waste water treatment.
研究领域:
环境科学
·
化学工程
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产品关联
DOI
PubMed
高影响因子
DESIGNED MONOMERS AND POLYMERS
·
2014
·
IF 2.21
Lin Jia,Dazhi Wang,Lijian Liu,Shaoyin Zhang,Tongkuan Xu
In the search for new materials to separate 2,4-dinitrophenol (DNP) from 2,4-dinitroanisole (DNAN), we have focused on the polymer design and synthesis of novel porous poly(amide-sulfonamide) (PASA) containing both repeated amide and sulfonamide functional groups from the reaction of m-chlorosulfonylbenzoyl chloride with 4,4′-diamino diphenyl sulfone in DMAc, using low-temperature solution polymerization. The structure and thermal property of the PASA were characterized by BET, SEM, FT-IR, 1H NMR, XRD, TGA; the selective removal of 2,4-DNP from DNAN solution was analysed by adsorption experiments. The BET, SEM and XRD results showed that the PASA with a porous morphology is nearly amorphous; the molecular weight of the polymer was investigated by GPC. Thermogravimetric analysis indicated that the reasonably high temperature recorded (>380 °C) before a 5% weight loss occurred. The removal rate of 2,4-DNP solution was 54.11% at 30 °C.
研究领域:
材料科学
·
环境科学
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产品关联
DOI
高影响因子
CATALYSIS LETTERS
·
2024
·Vol. 155
·期 1
·1-15
·
IF 2.3
Gao Qing,Yu Yingxue,Wang Chengyun,Xiang Rui,Lu Hao
Designing an efficient Pd-based catalyst with high atom utilization efficiency is a pressing priority, presenting a significant challenge for the practical deployment of electrocatalytic hydrodechlorination (EHDC), a promising method for degrading hazardous chlorophenols (CPs). Herein, a hybrid Pd/Co(OH) 2 /NF electrode for the dechlorination of 2,4- dichlorophenol (2,4-DCP) is fabricated by a newly developed etching-deposition approach. Physical characterizations demonstrate that ultra-fine Pd nanoparticles (1.57 ± 0.29 nm) accompany with Pd 2+ hydroxides are uniformly deposited on the surface of Co(OH) 2 nanowire arrays. EHDC tests on Pd/Co(OH) 2 /NF show an impressive catalytic performance with a 94.5% removal efficiency within 2 h, fast reaction kinetics (0.024 min − 1 ) and remarkable current efficiency (55.4%), highly competitive with literature reports. Mechanism investigations indicate that the even distribution of Pd nanoparticles and coexistence of Pd 2+ sites facilitate the production of active H * and activation of C-Cl, contributing to the improvement of activity.
研究领域:
环境科学
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材料科学
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产品关联
DOI
高影响因子
NEW JOURNAL OF CHEMISTRY
·
2022
·Vol. 46
·期 22
·10777-10786
·
IF 3.925
Xiaoxia Yu,Jianye Pei,Lihua Bi
To develop an excellent electrochemical sensor for the detection of 2,4-dinitrophenylhydrazine (2,4-DNPH), which has become a primary organic pollutant in the environment and is greatly poisonous, four polyoxometalates (POMs) with different structures (H3PW12O40: PW12, K6P2W18O62: P2W18, K12.5Nal.5[NaP5W30O110]·15H2O: P5W30, K28Li5H7P8W48·92H2O: P8W48) were chosen to investigate their sensing performance in solution and composite films towards the detection of 2,4-DNPH. The results indicated that the composite film containing P8W48 exhibited the best performance among the four POMs. The study focused on the effect of the layer number and solution pH on the sensing performance of the composite film containing P8W48, proving that the composite film with seven layers of P8W48 in pH 7 solution showed the optimal electrocatalytic activity for the reduction of 2,4-DNPH. Further, under the optimized conditions, the sensing performance of the P8W48-based composite film was evaluated by CV and i–t curves, giving a linear concentration range of 1 to 700 μM with a low detection limit of 0.012 μM. Moreover, the selectivity, stability, reproducibility and repeatability were examined, confirming that the developed sensor has good potential for determining 2,4-DNPH in the environment.
研究领域:
环境科学
·
分析化学
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DOI
高影响因子
RSC Advances
·
2016
·Vol. 6
·期 98
·95825-95835
·
IF 3.289
Hui Yuan,Qing liang You,Lin Jie Song,Gui ying Liao,Hua Xia,Dong Sheng Wang
The novel carbon nanotubes (CNT)/porous polyimide (PI) composites were prepared via blending and were characterized by Fourier transform infrared spectroscopy (FTIR), thermogravimetric analysis (TGA), transmission electron microscopy (TEM) and nitrogen adsorption–desorption techniques. The feasibility of CNT, CNT/PI (3/1) and CNT/PI (1/1) to remove 2,4-dichlorophenol (2,4-DCP) from an aqueous solution was examined. The influence of different parameters such as pH, ionic strength, contact time and temperature has been carried out. The results showed that PI was successfully combined with CNT and formed CNT/PI composites with higher adsorption capacity and shorter equilibrium time. The adsorption capability at 298 K of CNT, CNT/PI (3/1) and CNT/PI (1/1) composites were 330.0 mg g−1, 412.5 mg g−1 and 506 mg g−1, respectively. Their kinetic experimental data were better fitted by a pseudo-second-order model, and their adsorption isotherms could be represented by the Freundlich isotherm model perfectly. A thermodynamic study showed that the adsorption of 2,4-DCP on them was spontaneous and endothermic. Discoveries in this study suggest that the CNT/PI composites are promising adsorbents for removal of 2,4-DCP from aqueous solution.
研究领域:
环境科学
·
材料科学
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产品关联
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2018
·
IF 6.735
Jiasheng Zhou,Zimo Lou,Jiang Xu,Xiaoxin Zhou,Kunlun Yang,Xiaoyu Gao,Yilin Zhang,Xinhua Xu
In this study, a novel approach was developed for the dechlorination of 2,4-dichlorobenzoic acid (2,4-DCBA) via the combination of the moveable activated carbon (AC) supported palladium (Pd) nanoparticles and nickel (Ni) foam electrode. The morphology and chemical structure of Pd/AC catalyst was investigated by various characterization techniques, including SEM, TEM, EXS-mapping, XRD, and XPS. Pd nanoparticles was successfully loaded and dispersed on the AC, accompanied with the significantly enhanced reactivity. The removal rate of 2,4-DCBA by Ni electrode with moveable Pd/AC catalyst was 222, 25, and 5 folds higher than dispersed AC and Ni electrode system, chemical deposited Pd/Ni electrode, and electrodeposited Pd/Ni electrode, respectively. Compared with the conventional electrocatalytic reductive approach which deposited Pd on the Ni foam electrode, moveable Pd/AC catalyst possesses higher surface area, more atomic H ∗ production and more active sites, favored mass transfer, and enhanced reactivity, without the consideration of catalyst loss and deactivation. The effects of Pd:AC mass ratio, constant current, initial solution pH, and electrolyte concentration on the dechlorination of 2,4-DCBA were studied. Generally, high Pd loading, constant current, and acidity favored the dechlorination of 2,4-DCBA, while excessive electrolyte would inhibit the dechlorination of 2,4-DCBA. Good longevity and recyclability of moveable Pd/AC catalyst was confirmed via consecutive experiments. The findings of the present study show that making the catalyst moveable is a promising strategy for electrocatalytic remediation technology.
研究领域:
环境科学
·
化学工程
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产品关联
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2026
·
IF 12.5
Guangyuan Xu,Chuantian Ren,Weiguang Wang,Yufeng Wu,Yiqian Zhou,Ming Lei,Jingfeng Zhang,Kai Huang,Hui Wu
An electronic–ionic bicontinuous conductive network is designed to overcome the trade-off between conductivity and hydration stability in hydrogel electrodes. • The composite electrode maintains low skin–electrode impedance (<5 kΩ @ 10 Hz) for over 24 h (EEG) and 48 h (ECG), ensuring long-term interface stability. • Superior signal fidelity is achieved with an ECG signal-to-noise ratio of 50.4 dB, surpassing commercial Ag/AgCl electrodes by 8–10 dB. • Multimodal bioelectrical monitoring is demonstrated, including exercise ECG, dynamic EMG, and EEG (α rhythm and SSVEP analysis). • The work provides a generalizable materials strategy integrating high conductivity, flexibility, and long-term hydration for next-generation wearable bioelectronics. Developing high-performance electrodes for long-term, high-fidelity physiological monitoring remains a critical challenge in wearable healthcare. Here, we report a composite electrode formed by infiltrating a low-eutectic gel (choline chloride/glycerol/gelatin) into a nickel-coated polyurethane (PU@Ni) sponge, thereby establishing an electronic–ionic bicontinuous conductive network. The resulting electrode exhibits skin-adaptive mechanics (modulus of 0.21 MPa and fracture strain of 70%) and excellent environmental stability, retaining 95% of its initial mass after 48 h. Electrochemical characterization reveals a skin–electrode impedance below 5 kΩ at 10 Hz. In practical demonstrations, the electrode delivers high-quality ECG recording with a signal-to-noise ratio (SNR) of up to 50.4 dB, which is 8–10 dB higher than that of commercial Ag/AgCl electrodes, and maintains reliable performance during 48 h of continuous monitoring. Furthermore, EEG measurements show performance comparable to conventional wet electrodes, enabling stable, high-fidelity acquisition over 24 h. Overall, this work provides a scalable composite-engineering strategy to reconcile conductivity, mechanical compliance, and long-term durability, offering a promising platform for next-generation wearable bioelectronics.
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DOI
高影响因子
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