JOURNAL OF ELECTROANALYTICAL CHEMISTRY
·
2019
·
IF 3.218
Yanjie Chen,Shupei Zhang,Xiuhua Li,Hong Dai,Yanyu Lin
A versatile TiO 2 mesocrystals trigged signal amplification photoelectrochemical (PEC) sensing platform was designed for sensitive and accurate determination of α-fetoprotein (AFP). To construct such a biosensor, Bi 2 S 3 nanosheets with notable visible light photoactivity and biocompatibilities were employed as electron transfer mediator as well as a substrate for AFP antigen immobilization. Meanwhile, the Polyethylenimine (PEI) functionalized TiO 2 mesocrystals was used to anchor AFP antibody and the resulting composite Ab-TiO 2 -PEI was utilized as trace tag for signal amplification. The trace tag anchored onto the electrode interface via indirect competitive recognition between free target AFP and immobilized AFP to combine Ab-TiO 2 -PEI. As a result, a cascade structure of band-edge levels formed between TiO 2 mesocrystals and Bi 2 S 3 nanosheets, which notably promoted the photo-to-current conversion efficiency and enhance photocurrent response significantly. By merit of these, the concentration of AFP could be accurately determined through an indirect competitive reaction immunoassay . Upon the optimal condition, this PEC biosensor performed favorable sensitivity, selectivity and reproducibility. Hence, the designed indirect competitive PEC immunoassay possesses a potential application for clinical test and will inspire more development of simple and practical PEC sensor toward different biomolecules.
研究领域:
分析化学
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生物传感器
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光电化学
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免疫分析
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产品关联
DOI
高影响因子
ACS Applied Nano Materials
·
2025
·
IF 5.5
Lejing Qin,Fangyu Gong,Zi Ma,Kai Li,Linzheng Ma,Wei Chen
Self-powered photoelectrochemical (PEC) sensing platforms, which integrate a photoanode with a sensing cathode, have emerged as transformative strategies for analyzing biological samples due to their robust photocurrent responses and outstanding anti-interference capabilities. Building on this concept, a self-powered PEC aptasensor was designed to achieve the highly accurate and selective detection of thrombin (TB). The photoanode was constructed by sequentially modifying a bare indium tin oxide (ITO) electrode with titanium dioxide (TiO2) powder, aqueous cadmium telluride quantum dots (CdTe QDs), and poly(3,4-ethylenedioxythiophene) (PEDOT), resulting in a cosensitized TiO2/CdTe/PEDOT structure. The sensing cathode was prepared by electrodepositing reduced graphene oxide (RGO) onto an ITO substrate, followed by the immobilization of a TB-specific aptamer on the ITO/RGO surface. This spatial separation of the photoanode and cathode offers two key advantages: enhanced photoresponse and stable photocurrent compared to traditional cathodic PEC systems, as well as excellent sensitivity and selectivity with strong resistance to interference from reductive species and photoexcitation of the cathode. This self-powered PEC aptasensor demonstrates a highly reliable and efficient platform for target analyte detection, showcasing a superior performance and significant potential for diverse applications in biomolecular sensing.
研究领域:
生物传感
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分析化学
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材料科学
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产品关联
DOI
高影响因子
MICROCHIMICA ACTA
·
2018
·Vol. 185
·期 3
·1-10
·
IF 5.705
Wang Yan,Bian Feng,Qin Xiaofei,Wang Qianqian
A visible-light driven photoelectrochemical (PEC) aptasensor is described that is capable of detecting chloramphenicol (CAP). It is based on the use of a TiO 2 based nanorod array (NRA) sensitized with Eu(III)-doped CdS quantum dots. The NRA absorbs visible-light and while strongly depressing the recombination of photogenerated charges, thereby improving photo-to-current conversion efficiency. The introduction of Eu(III) ions promotes the charge transformation and utilization, and this results in a further increase of photocurrent. The NRA was employed as the photoactive material for the fabrication of a PEC aptasensor. CAP-binding aptamers were immobilized on a fluorine-doped tin oxide (FTO) electrode that was modified with the NRA. The aptasensor was applied to the determination of CAP by monitoring the decrease in photocurrent (at a typical voltage of 0 V) that is caused by the formation of the aptamer-CAP complex. Under optimal conditions, the response is linear in the 1.0 pM to 3.0 nM CAP concentration range, with a detection limit of 0.36 pM (at S/ N = 3). The method was applied to the determination of CAP in spiked milk samples where it gave satisfactory results.
Schematic presentation of the fabrication of a visible-light driven photoelectrochemical aptasensor based on the use of a TiO 2 nanorod array sensitized with Eu(III)-doped CdS quantum dots. It was applied to the determination of chloramphenicol with good selectivity and high sensitivity. TiO 2 NRA: TiO 2 nanorod array; FTO: fluorine-doped tin oxide; CdS:Eu 3+ QDs: Eu(III)-doped CdS quantum dots; BSA: bovine serum albumin; CAP: chloramphenicol
研究领域:
分析化学
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生物医学工程
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产品关联
DOI
PubMed
高影响因子
RSC Advances
·
2017
·Vol. 7
·期 60
·37806-37814
·
IF 3.108
Anlin Xu,Xiang Dai,Kajia Wei,Weiqing Han,Jiansheng Li,Xiuyun Sun,Jinyou Shen,Lianjun Wang
The broad application of highly electrocatalytic SnO2–Sb electrodes for wastewater treatment is limited by their short service lifetime. Herein, a novel substrate structure, tubular porous titanium, was applied to prepare a TiO2-NT/SnO2–Sb electrode, which could greatly improve the stability of the electrode for electrochemical oxidation process. Based on the analysis conducted using a field emission scanning electron microscope (FE-SEM), linked with an energy dispersive spectrometer (EDS), it was demonstrated that a solid solution between Sn and Sb presented a smooth surface of the tubular porous electrode. The crystalline structure and chemical composition of the electrode coating are determined by X-ray diffraction (XRD). Accelerated service life test reveals that under the 0.2 A cm−2 current density in a 0.5 M H2SO4 solution, the TiO2-NT/SnO2–Sb tubular porous electrode has the longest accelerated service lifetime of 68.9 h, which is 10.9 times that of the TiO2-NT/SnO2–Sb plate electrode. Cyclic voltammetry curves (CVs) and linear sweep voltammetry curves (LSVs) reveal the enhanced electroactive surface area and higher oxygen evolution potential (OEP = 1.85 V vs. Ag/AgCl) of the electrode. Moreover, the TiO2-NT/SnO2–Sb tubular porous electrode has the larger outer voltammetric charge q*. During the electrochemical oxidation of pyrimidine, the tubular system constructed using the TiO2-NT/SnO2–Sb tubular porous electrode as the anode also exhibited best electrocatalytic performance, and 97.9% pyridimine removal efficiency and 79.4% COD removal efficiency at 6 h were achieved.
研究领域:
环境科学
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材料科学
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产品关联
DOI
高影响因子
RSC Advances
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2016
·Vol. 6
·期 86
·83406-83411
·
IF 3.289
Gao-Ming Hou,Ming-Qiu Zhang,Yi-Fu Huang,Wen-Hong Ruan
This paper has reported a new polymer nanocomposite of nano-titanium dioxide/polyethylene oxide (TiO2/PEO) incorporated with in situ synthesized hyper-branched poly(amine-ester) (HBPAE) and its application as a polymer electrolyte. Firstly, the HBPAE/HBPAE-g-TiO2/PEO is obtained by synthesizing HBPAE in methyl acrylic acid methyl ester grafted TiO2 (MMA-g-TiO2)/PEO, to simultaneously form the hypergrafted polymer on the nano inclusions (HBPAE-g-TiO2) and hyperbranched particles dispersed in the PEO. Then the Li2SO4 is introduced to prepare the polymer electrolyte, and the relevant structure and properties are studied. It is found that the incorporation of HBPAE into TiO2/PEO can benefit the ionic transportation of the composite electrolyte, and can bridge the nano inclusions which further improves ionic conductivity. The best ionic conductivity of the HBPAE/HBPAE-g-TiO2/PEO polymer electrolyte with 15 wt% TiO2 content can reach as high as 3.2 mS cm−1, which is ∼10 times of that of the PEO electrolyte and ∼28% of that of the HBPAE-g-TiO2/PEO electrolyte without homopolymer component. Furthermore, the optimized polymer electrolyte is assembled into a LiTi2(PO4)3//LiMn2O4 lithium-ion battery, with better excellent cell performance compared with the PEO electrolyte. This study shows that the new polymer nanocomposite has great potential for the assembly of high performance solid electrochemical devices.
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DOI
高影响因子
NEW JOURNAL OF CHEMISTRY
·
2016
·Vol. 40
·期 4
·3225-3232
·
IF 3.277
Han Zheng,Changhua Wang,Xintong Zhang,Lina Kong,Yingying Li,Yunyu Liu,Yichun Liu
Multi-heterojunctions are more promising than single-heterojunctions in photocatalysis due to the availability of more interfaces between each component. However, photocatalytic activity is highly dependent on the contact mode of individual components. In this work, we assemble TiO2–WO3–Pt multi-heterojunction microspheres using ultrasonic spray pyrolysis and focus on their contact mode governed photocatalytic activity. The results reveal that using highly crystalline WO3 nanosheets as building blocks could particularly enhance the photocatalytic activity of a TiO2/WO3 system toward the degradation of gaseous acetaldehyde and isopropyl alcohol. Furthermore, loading Pt nanoparticles onto WO3 nanosheets could facilitate a more prominent enhancement of activity than that of TiO2/Pt, benefiting from the two-electron reduction of oxygen at the interface of WO3/Pt. Meanwhile, the high crystallinity of WO3 nanosheets allows for a loading amount of Pt as low as 0.04 wt% in the TiO2–WO3–Pt system, which reduces the catalyst cost in comparison with that of the conventional amount of 1 wt%.
研究领域:
材料科学
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环境科学
·
催化化学
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产品关联
DOI
高影响因子
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
·
2018
·
IF 3.235
Xiezhen Zhou,Siqi Liu,Hongxia Yu,Anlin Xu,Jiansheng Li,Xiuyun Sun,Jinyou Shen,Weqing Han,Lianjun Wang
A highly ordered three-dimensional macro-porous PbO 2 (3D porous PbO 2 ) electrode has been prepared for electrochemical oxidation of nitrogen-heterocyclic compounds. The 3D porous PbO 2 electrode was fabricated by templated electrochemical deposition method with TiO 2 nanotube arrays as substrate and SnO 2 -Sb as intermediate layer. The morphology and composition characterization of the 3D porous PbO 2 electrode was performed by field emission scanning electron microscopy and X-ray diffraction, which revealed a uniform distribution of highly ordered macro-porous β-PbO 2 structure. The Brunner−Emmet−Teller analysis suggested the electrode possessed large specific surface area of 37.39 m 2 ·g −1 . Electrochemical measurements indicated the electrode had a favourable oxygen evolution potential of 1.89 V and inner voltammetric charge of 14.48 mC·cm −2 , which were higher than that of conventional PbO 2 electrode. Furthermore, the electrochemical oxidation and TOC removal percentage of pyrrole , pyrazole and tetrazole obtained by 3D porous PbO 2 electrode were 93.4%, 72.7%, 61.2% and 66.7%, 57.3%, 38.6% respectively, which were also superior to conventional PbO 2 electrode. The intermediates were detected and analyzed by high-performance liquid chromatography, gas chromatography-mass spectrometer, and ion chromatography to propose a degradation pathway of pyrrole, pyrazole and tetrazole. Finally, quantum chemical calculation was introduced in this study by density function theory method, which is consistent with the experimental detection.
研究领域:
环境科学
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材料科学
·
化学工程
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产品关联
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2023
·
IF 15.1
Dapeng Li,Yongping Fang,Jia Lu,Jinao Sun,Xin Zhao,Ning Hou,Jie Xing
Biochar (BC) and its composites have been widely used for pollutant treatment upon their adsorption and photocatalytic efficiency, but their toxicity and ecological effects have received little attention. In this study, BC was prepared and modified with nano-titanium dioxide to obtain BC composite (TiO 2 @BC), then the biotoxicity and ecological effects were investigated from two dimensions (single bacteria and microflora). In detailed, the effects of different dosage of BC and TiO 2 @BC on the degradation function, growth characteristics and toxicity mechanism of the strain Achromobacter sp. LH-1 were comprehensively studied. It was found that when the dosage of BC and TiO 2 @BC was less than or equal to 0.5 g/L, the degradation function of LH-1 was enhanced, but the effect on growth was negligible. However, when the dose exceeded 0.5 g/L, a large amount of ROS accumulated, which inhibited the cell respiratory chain and destroyed the cell wall. In another word, ·OH and ·O 2 – generated by BC and TiO 2 @BC played important roles in the inactivation of LH-1. Furthermore, a laboratory scale bioreactor (SBR) was built and applied to study the ecological effects of BC and TiO 2 @BC, and it was found that proper amount (0.5 g/L) of BC and TiO 2 @BC can not only effectively remove polycyclic aromatic hydrocarbons (PAHs) pollutants, but also increase the diversity of microbial communities, and promote the carbon and nitrogen cycle in the sewage system. This study analyzes the ecotoxicity risk of BC and TiO 2 @BC under photocatalysis in detail, which has important reference value for future practical applications in ecosystems.
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DOI
高影响因子
ACS Applied Bio Materials
·
2022
·
IF 0
Jinglin Zhang,Huakai Chen,Tongyao Lin,Fengjuan Yang,Jingxian Zhang,Xiang Cai,Yunhua Yang,Peng Zhang,Shaozao Tan
Titanium (Ti) is an excellent medical metal material, but the absence of good antibacterial property restricts its widespread application. To overcome this, we thus conducted a series of modifications for Ti. First, a titanium dioxide (TiO2) nanorod array was generated on the Ti surface by hydrothermal treatment (TiO2/Ti). With the polymer-mediated self-assembly method, a continuous copper (Cu) shell structure on the surface of the nanorod was then generated to form a TiO2@Cu core–shell nanorod array as coating for Ti (TiO2@Cu/Ti). Using pure Ti as the control group, the antibacterial properties of TiO2/Ti and TiO2@Cu/Ti were appraised. The results manifested that the mechanical and chemical dual function of the released Cu2+ and TiO2 nanorod array could effectively kill bacteria on the surface of Ti. Besides, the obtained coating exhibited no cytotoxicity and favorable biocompatibility. In this work, we found an antibacterial strategy based on multiple sterilization pathways, which made Ti have good antibacterial property and further improved its biocompatibility.
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产品关联
DOI
PubMed
ACS Applied Nano Materials
·
2024
·
IF 5.3
Xiaoyan Song,Wanchun Huang,Runbin Ge,Hao Wang,Jinfeng Xing
Conventional polyolefin separators used in lithium-ion batteries face challenges for low porosity, insufficient electrolyte wettability, poor thermal stability, and short circuits caused by dendrite growth. In this work, a unique polyimide/trisilanol isobutyl sesquisiloxane@titanium dioxide fiber separator is prepared by electrospinning and self-assembly, in which polyhedral oligomeric semisiloxane (POSS) serves as a bridge between polyimide (PI) and TiO2. The PI/trisilanollsobutyl (TS)-POSS@TiO2 nanofiber separator with a core–shell structure presenting excellent mechanical strength and electrochemical characteristic effectively inhibits the development of lithium dendrites in lithium-ion batteries. The PI/TS-POSS@TiO2 membrane tensile strength is 17.90 MPa, 152% greater than the pure PI separator tensile strength (7.1 MPa). The lithium-ion battery assembled with a PI/TS-POSS@TiO2 separator has an excellent conductivity of 1.782 mS/cm, which is 92.44% greater than that of a pure PI separator. Its electrochemical stability window also reaches 5.27 V. The lithium-ion battery assembled by the PI/TS-POSS@TiO2 separator exhibits excellent rate performance, cycling stability, and preferable resistance to dendritic penetration. The PI/TS-POSS@TiO2 nanofiber separator has good application prospects in lithium-ion secondary batteries.
研究领域:
材料科学
·
能源科学
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产品关联
DOI
高影响因子
FOOD CHEMISTRY
·
2022
·
IF 9.231
Chen Chen,Ximo Wang,Yingfang Zhang,Xingying Li,Huiju Gao,Geoffrey I.N. Waterhouse,Xuguang Qiao,Zhixiang Xu
Herein, a molecularly imprinted surface-enhanced Raman spectroscopy (SERS) sensor was developed for the selective capture and sensitive detection of tryptamine in foods. The SERS sensor exploited silver nanoparticle-decorated TiO 2 (TiO 2 @Ag) substrates for Raman signal enhancement via synergistic effect of electromagnetic enhancement and photoinduced charge-transfer, whilst surface functionalization with the molecularly imprinted polymer ensured selective tryptamine capture. The SERS spectrum of tryptamine on the sensor closely matched that predicted by density functional simulations. The SERS intensity for tryptamine on the developed TiO 2 @ [email protected] sensor increased linearly with the logarithm of the tryptamine concentration over the range of 10 −6 –10 −2 mol L −1 , with a LOD of 4.85 × 10 −7 mol L −1 . Tryptamine was detected in a spiked white vinegar sample, and its recoveries were in the range of 92.00%–111.40%. The SERS sensor could be used for the detection of tryptamine in actual samples.
研究领域:
分析化学
·
纳米技术
·
食品科学
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DOI
PubMed
高影响因子
ANALYTICAL CHEMISTRY
·
2025
·
IF 6.7
Xuran Tian,Linyue Tang,Yulan Zeng,Zhonghui Chen,Bin Qiu,Zhenyu Lin,Huixing Chen
This study developed an organic photoelectrochemical transistor (OPECT) biosensor based on TiO2-embedded vertically ordered mesoporous silica film (VMSF) modified ITO electrode for ultrasensitive detection of carcinoembryonic antigen (CEA). The sensor uses VMSF as a molecular gate, with the complementary DNA (cDNA) of the CEA aptamer immobilized at the entrances of the mesoporous channels for specific target recognition. In the absence of CEA, cDNA and the aptamer form stable double-stranded DNA (dsDNA), blocking Ru(phen)32+ from entering the channels and suppressing the photoelectrochemical signal. When CEA is present, it triggers the release of cDNA, which is cleaved by exonuclease I (Exo I), opening the molecular gate and enhancing the photocurrent signal. The Exo I-assisted signal amplification strategy significantly improves the sensor’s sensitivity. Additionally, TiO2 nanoparticles are embedded in the VMSF channels, combining TiO2’s photoelectrochemical properties with VMSF’s molecular sieving function, optimizing charge separation and migration efficiency, and enhancing the photoelectrochemical signal. The energy level alignment between TiO2 and Ru(phen)32+ promotes photoelectric conversion efficiency, while the negative charge on VMSF improves antifouling ability and selectivity. Furthermore, the positively charged Ru(phen)32+ can enters and accumulated in the mesopores of negatively charged VMSF through electrostatic interactions, thereby enhancing the detected signal output under light irradiation. The sensor has a detection range of 100 fg/mL to 500 ng/mL and a minimum detection limit of 0.031 pg/mL, significantly outperforming conventional sensors, demonstrating broad clinical application potential.
研究领域:
生物传感器
·
光电化学检测
·
纳米材料
·
临床诊断
·
癌症标志物
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电分析化学
·
有机电子学
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产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）