NPG Asia Materials
·
2018
·Vol. 10
·期 3
·e472
·
IF 7.208
Chen Zhonghui,Lv Ziyu,Wang Xue,Yang Hong,Qing Guangyan,Sun Taolei
Increasing evidence has indicated that glycans and their interactions with glycan-specific binding proteins have crucial roles in most physiological processes. One emerging topic in biomaterials is the construction of smart materials capable of recognizing and responding to these valuable glycans. However, because of the complicated compositions and structures as well as the low abundances and microheterogeneity of glycans, developing glycan-responsive materials with a high sensitivity and specificity is a long-term, challenging goal. Here, we report a biomimetic polymer capable of capturing and discriminating sialo-complex-type glycans with the core Neu5Ac-Gal-GlcNAc-Man sequence, which is one of the most effective biomarkers for cancer detection. As an optimized dipeptide, L-Asp-L-Phe has a strong but differential binding affinity for N -acetyl-neuraminic acid (Neu5Ac), N -acetyl-glucosamine (GlcNAc), galactose (Gal), and mannose (Man), which are the core construction units of sialylated glycans. In addition, the L-Asp-L-Phe-grafted polyethyleneimine film displays remarkable adsorption behavior for the model sialylated glycans and can discriminate their linkage isomers, which is accompanied by significant changes in the surface morphology and stiffness. These features facilitate the highly selective capture of sialylated glycopeptides from complex protein samples using PEI- g -L-Asp-L-Phe-modified mSiO 2 @SiO 2 @Fe 3 O 4 core-shell microspheres. The mechanism analysis demonstrates that the favorable polymeric spatial structures and multiple synergetic hydrogen-bonding interactions among the dipeptides and glycan are the main driving forces, indicating a clear direction for designing glycan-specific biomaterials.
研究领域:
生物材料学
·
分子生物学
·
医学工程
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产品关联
DOI
高影响因子
NPG Asia Materials
·
2016
·Vol. 8
·期 7
·e292
·
IF 8.772
Qu Sanyin,Yao Qin,Wang Liming,Chen Zhenhua,Xu Kunqi,Zeng Huarong,Shi Wei,Zhang Tiansong,Uher Ctirad,Chen Lidong
Conducting polymers are potential candidates for thermoelectric (TE) applications owing to their low thermal conductivity, non-toxicity and low cost. However, the coil conformation and random aggregation of polymer chains usually degrade electrical transport properties, thus deteriorating TE performance. In this work, we fabricated poly(3-hexylthiophene) (P3HT) films with highly oriented morphology using 1,3,5-trichlorobenzene (TCB), an organic small-molecule, as a template for polymer epitaxy under a temperature gradient crystallization process. The resulting P3HT molecules, which were confirmed to be highly anisotropic by a combination of scanning electron microscopy, atomic force microscopy, polarizing microscope, polarized Raman spectroscopy, and two-dimensional-grazing incidence X-ray diffraction (GIXRD) analysis, not only markedly reduced the conjugated defects along the polymer backbone, but also effectively increased the degree of electron delocalization. These combined phenomena produced an efficient, 1D path for carrier movement and therefore resulted in enhanced carrier mobility in the TCB-treated P3HT films. The maximum values of the electrical conductivity and Seebeck coefficient were 320 S cm −1 and 269 μV K −1 , respectively. Consequently, the maximum TE power factor and ZT value at 365 K reached 62.4 μW mK −2 and 0.1, respectively, in the parallel direction of the TCB-treated P3HT film. To the best of our knowledge, these are the highest values reported for pure P3HT TE materials. The method of using organic small-molecule epitaxy to generate highly anisotropic polymer films is expected to be valid for many conducting polymers.
研究领域:
材料科学
·
物理化学
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产品关联
DOI
高影响因子
NPG Asia Materials
·
2016
·Vol. 8
·期 3
·e243
·
IF 8.772
Ning Chengyun,Yu Peng,Zhu Ye,Yao Mengyu,Zhu Xiaojing,Wang Xiaolan,Lin Zefeng,Li Weiping,Wang Shuangying,Tan Guoxin,Zhang Yu,Wang Yingjun,Mao Chuanbin
Bone has a built-in electric field because of the presence of piezoelectric collagen. To date, only externally applied electric fields have been used to direct cell behavior; however, these fields are not safe or practical for in vivo use. In this work, for the first time, we use a periodic microscale electric field (MEF) built into a titanium implant to induce osteogenesis. Such a MEF is generated by the periodic organization of a junction made of two parallel semiconducting TiO 2 zones: anatase and rutile with lower and higher electron densities, respectively. The junctions were formed through anatase–rutile-phase transition in selective areas using laser irradiation on the implants. The in vitro and in vivo studies confirmed that the built-in MEF was an efficient electrical cue for inducing osteogenic differentiation in the absence of osteogenic supplements and promoted bone regeneration around the implants. Our work opens up a new avenue toward bone repair and regeneration using built-in MEF.
研究领域:
生物材料
·
组织工程
·
生物医学工程
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产品关联
DOI
PubMed
高影响因子
COLLOID AND POLYMER SCIENCE
·
2020
·Vol. 298
·期 8
·1053-1061
·
IF 1.536
Cai Shuwei,Gu Shiyu,Li Xian,Wan Songhan,Chen Songbo,He Xianru
A controlled grafting modification starch exhibited tunable phase transition temperature in aqueous solution was prepared via reversible addition–fragmentation chain transfer (RAFT) polymerization and esterification reaction under mild condition. P(AM/AN) copolymer was grafted onto the starch backbone and endowed the grafted copolymer thermosensitivity. The molecular structure and composition of P(AM/AN) copolymers were characterized by gel permeation chromatography (GPC), FTIR, and NMR, indicating a structurally controllable side chain of the grafted copolymer. Results of X-ray diffraction (XRD) demonstrate that the crystallinity of grafted copolymer decreases compared with starch due to side chains destruct the structural regularity of starch. Scanning electron microscopy (SEM) images show that grafted copolymer displays a rough, multilayer, and irregular morphology. Dynamic light scattering (DLS) and UV tests indicate that the grafted copolymer forms aggregates in aqueous solution and the UCST of the grafted copolymer is dependent on percent grafting (PG) and molecular interactions of side chains.
研究领域:
高分子化学
·
材料科学
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DOI
高影响因子
Science of Advanced Materials
·
2019
·Vol. 11
·期 6
·842-853
·
IF 1.158
Xu Qiyao,Liu Hongxia,Zheng Huaili,Liang Jianjun
In this study, a new cationic polyacrylamide (CPAM) was successfully synthesized through UV-H2O2-initiated polymerization technique using acryloyloxyethyl trimethyl ammonium chloride (DAC) and acrylamide (AM) as monomers, and applied to sludge dewatering experiments.
Parameters affecting the molecular weight and conversion of the polymers, including total monomer concentration, monomer concentration of DAC, H2O2 concentration, pH and illumination time were examined. Fourier transform infrared spectroscopy (FT-IR), 1H nuclear
magnetic resonance spectroscopy (1H NMR), thermogravimetric analysis (TGA) and scanning electron microscopy (SEM) were employed to characterize the properties of the polymers. The results showed that CPAM was successfully synthesized and possessed a coarse and porous surface morphology
and inferior thermal stabilities. When the dosage of polymer was 40 mg L–1 and the initial sludge pH value was 7.0, PAD-3 (cationic degree: 40%, molecular weight: 6.89 × 106 Da) showed a more excellent sludge dewatering performance (FCMC: 70.6% SRF: 2.8 ×
1012 m · kg –1; d
50: 436.802 μm, Df
: 1.59). During the sludge flocculation process, three mechanisms containing charge neutralization, patching and bridging co-contributed to a prominent flocculation performance.
研究领域:
环境科学
·
高分子化学
✓ 已验证
DOI
高影响因子
Gels
·
2023
·Vol. 9
·期 6
·489
·
IF 4.6
Yunling Ran,Guicai Zhang,Ping Jiang,Haihua Pei
High water cut of produced fluid is one of the most common problems in reservoir development. At present, injecting plugging agents and other profile control and water plugging technologies are the most widely used solutions. With the development of deep oil and gas resources, high-temperature and high-salinity (HTHS) reservoirs are becoming increasingly common. Conventional polymers are prone to hydrolysis and thermal degradation under HTHS conditions, making polymer flooding or polymer-based gels less effective. Phenol–aldehyde crosslinking agent gels can be applied to different reservoirs with a wide range of salinity, but there exist the disadvantage of high cost of gelants. The cost of water-soluble phenolic resin gels is low. Based on the research of former scientists, copolymers consisting of acrylamide (AM) and 2-Acrylamido-2-Methylpropanesulfonic acid (AMPS) and modified water-soluble phenolic resin were used to prepare gels in the paper. The experimental results show that the gelant with 1.0 wt% AM-AMPS copolymer (AMPS content is 47%), 1.0 wt% modified water-soluble phenolic resin and 0.4 wt% thiourea has gelation time of 7.5 h, storage modulus of 18 Pa and no syneresis after aging for 90 days at 105 °C in simulated Tahe water of 22 × 104mg/L salinity. By comprehensively comparing the effectiveness of the gels prepared by a kind of phenolic aldehyde composite crosslinking agent and modified water-soluble phenolic resin, it is found that the gel constructed by the modified water-soluble phenolic resin not only reduces costs, but also has shorter gelation time and higher gel strength. The oil displacement experiment with a visual glass plate model proves that the forming gel has good plugging ability and thus improves the sweep efficiency. The research expands the application range of water-soluble phenolic resin gels, which has an important implication for profile control and water plugging in the HTHS reservoirs.Keywords:low-cost gel;AM-AMPS copolymer;high-temperature and high-salinity resistant gel;oil displacement experiment
研究领域:
石油工程
·
材料科学
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产品关联
DOI
PubMed
高影响因子
Journal of Chemistry
·
2025
·Vol. 2025
·期 1
·9994523
·
IF 2.6
Jun Li,Yinliang Bao,Xiaojuan Tu,Yuedong Li,Xiaoping Qin,Cuixia Li,Song Qing
A hydrophobic associative polymer (AM-AA-SSS-DMCAAC 16 ) was synthesized using the aqueous polymerization method with acrylic acid (AA), acrylamide (AM), sodium styrene sulfonate (SSS), and hexadecyl dimethylallyl ammonium chloride (DMCAAC 16 ) as the main raw materials and ammonium persulfate sodium bisulfite as the initiator. The synthesis conditions for AM-AA-SSS-DMCAAC 16 are as follows: a total monomer mass concentration of 25%, an initiator dosage of 0.2% of the total monomer mass, a reaction temperature of 40°C, and a reaction time of 4 h. The structure of AM-AA-SSS-DMCAAC 16 was characterized by infrared spectroscopy, nuclear magnetic resonance hydrogen spectroscopy, and scanning electron microscopy. The viscosity enhancement, shear resistance, temperature resistance, salt resistance, and oil displacement performance of AM-AA-SSS-DMCAAC 16 were studied. The experimental results showed that the apparent viscosity of the 2000 mg/L AM-AA-SSS-DMCAAC 16 solution prepared with injected water at 25°C was significantly higher than that of the same concentration of acrylamide and acrylic acid binary copolymer (AM-AA) solution. The viscosity of a 2000 mg/L AM-AA-SSS-DMCAAC 16 solution prepared with a 5000 mg/L sodium ion solution is 247.27 mPa s, which is 137.34 mPa s higher than the same concentration of AM-AA solution. After mechanical shearing at 28,000 r/min for 30 s, the viscosity retention rate of the 2000 mg/L AM-AA-SSS-DMCAAC 16 solution was 11.99% higher than that of the same concentration AM-AA solution. Under the same experimental conditions, the enhanced oil recovery rates of AM-AA and AM-AA-SSS-DMCAAC 16 were 11.28% and 17.49%, respectively, and AM-AA-SSS-DMCAAC 16 showed good oil displacement ability.
研究领域:
高分子化学
·
石油工程
·
材料科学
·
应用化学
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产品关联
DOI
高影响因子
Polymers
·
2025
·Vol. 17
·期 5
·656
·
IF 4.9
Miao Li,Yifan Zhang,Zhilin Du,Yao Zheng,Senbiao Liu,Hongjie Luo,Waraz Abdul,Jianfeng Zhu
Soil ruins hold historical significance and serve as witnesses to past civilizations. High temperatures cause soil moisture to evaporate and soil to shrink, leading to cracking issues and making preservation a global challenge. P(AA-AM-AMPS) (Acrylic acid -Acrylamide-2-Acrylamide-2-methy-propenesulfonic acid) composites solve this problem by combining absorbent materials with loess. In this study, P(AA-AM-AMPS) was prepared using a solution method. The water absorption, water retention, air permeability, and compressive strength of P(AA-AM-AMPS) in loess were studied. The results show that after adding P(AA-AM-AMPS) to loess, there is no obvious color difference compared with the blank sample, and the air permeability of the reinforced loess is basically the same as that of the blank soil. After aging resistance tests, the surface cracking of soil clods is significantly reduced compared to that of the blank samples, and their compressive strength improved from 1.8 N/mm2to 2.6 N/mm2.
研究领域:
土力学
·
材料科学
·
文物保护
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产品关联
DOI
PubMed
高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
·
2020
·Vol. 137
·期 35
·49016
·
IF 2.52
Guancheng Jiang,Kai Wang,Yinbo He,Lili Yang,Xinliang Li,Yu Deng
To meet the increasing requirement of stabilizing shale under high-temperature situation with the use of water-based drilling fluids (WBDFs), the high-performance shale stabilizer is an urgent need. In this study, an amphoteric copolymer of AM/DMDAAC/NVP (APC) was synthesized by acrylamide (AM), dimethyl diallyl ammonium chloride (DMDAAC), and N -vinylpyrrolidone (NVP) and used as a high temperature-resistant shale stabilizer. The Fourier transform infrared spectroscopy and nuclear magnetic resonance spectroscopy confirmed the successful synthesis of APC. The inhibitive performance of APC was systematically evaluated and compared with three other commonly used shale stabilizers, including the anionic potassium polyacrylamide (KPAM), cationic poly dimethyl diallyl ammonium chloride (PD), and amphoteric polymer FA367. The results demonstrated that APC displayed excellent performance on the linear swelling test, hot-rolling recovery experiment, and shale immersion test. Furthermore, APC combined the advantages of high shale recovery percentages of PD and maintaining shale pellet integrity of KPAM, avoiding the drawbacks of enormous filtration volume of PD and low shale recovery percentages of KPAM. These great properties indicated that APC would be suitable as a shale stabilizer in WBDF to drill high-temperature shale formation.
研究领域:
化学工程
·
材料科学
✓ 已验证
DOI
高影响因子
Analytical Methods
·
2020
·Vol. 12
·期 31
·3933-3943
·
IF 2.596
Qiuyue Yin,Maiqian Nie,Zhenjun Diwu,Yuting Zhang,Lei Wang,Dandan Yin,Liancheng Li
A rapid method for readily detecting the total numbers of viable bacterial cells in numerous samples (including surface water, solid inoculants, and soil samples) is reported using a newly developed hand-held fluorometer and a fluorescent dye Calcein UltraGreen™ AM. Compared to the traditional plate counting method that requires 48 hours of cultivation, the newly established method does not require any incubation time, making the detection method faster and more convenient. The portable rapid detection fluorometer has a wide dynamic range of relative fluorescence intensity from 45 to 30 133. It can detect bacterial concentration ranging from 105 to 1010 cells per mL. This newly established method has good applicability for accurately and quickly detecting the cell number of viable bacteria in various samples. The results of the fluorescence-based method were compared with those of the traditional plate counting method, and it was found that the relative standard deviation was less than 6%. This new rapid measurement system provides a robust method for the rapid on-site detection of viable bacteria.
研究领域:
微生物学
·
环境科学
·
分析化学
✓ 已验证
DOI
PubMed
高影响因子
CERAMICS INTERNATIONAL
·
2019
·
IF 3.45
Pan Gao,Le Zhang,Qing Yao,Cen Shao,Shuai Wei,Tianyuan Zhou,Hao Chen,Hao Yang
Aqueous gelcasting has been applied to form multiple advanced ceramics with large size or complex shape. However, the optical performance of transparent ceramics fabricated by gelcasting is not satisfactory due to the microstructure defects and residual organics. YAG ceramics with excellent optical transmittance were prepared through improving solid content of suspension, obtaining fine microstructure of fully dense ceramics without residual organics in this paper. The effects of ammonium citrate tribasic (TAC) and solid content on the rheological performance of suspension as well as the effect of solid content on the microstructure of green body were systematically investigated. The viscosity of suspension with 43 vol% solid content and 0.25 wt% TAC was as low as 0.03 Pa s at 100 s −1 . The YAG ceramics (thickness 2.5 mm) with high optical transmittance (T = 83.2% at 1064 nm) were prepared from 43 vol% after vacuum sintering at 1780 °C for 8 h. The green body cast from 45 vol% solid content had an excellent bending strength about 29 MPa, and the residual pores were eliminated after vacuum sintering, while the residual organics was detected by optical microscopy and elemental analyzer inside YAG ceramics. The residual organics results in the decrease of in-line transmittance of YAG ceramic cast from 45 vol% solid content than that of ceramic cast from 43 vol%. This study suggests a promising prospect for AM gelling system in the cost-efficient manufacturing of highly transparent ceramics with high bending strength of green bodies.
研究领域:
材料科学
·
光学工程
✓ 已验证
DOI
高影响因子
Geoenergy Science and Engineering
·
2024
·
IF 0
Yuhan Wu,Ming Duan,Qihai Wang,Bin Chen,Huaxin Chen,Xinliang Li,Shenwen Fang
Sand production in oil wells is a common challenge during the oil extraction process. Water-soluble polymers have attracted attention due to their low toxicity, cost-effectiveness, ease of direct injection, and excellent thermal stability. However, the dry polymer injection process commonly used in offshore oil fields is complex. Therefore, this paper employs acrylamide (AM), 2-acrylamide-2-methylpropane sulfonic acid (AMPS), a dihydroxy monomer (DOH), and a functional monomer (DAM) containing ketone groups and self-crosslinking properties as monomers. A polymer latex type sand control agent was prepared through dispersion polymerization for direct application on offshore platforms. This paper utilizes flocculation time and maximum sand free flow rate as inspection indicators and utilizes both the one-factor-at-a-time method and the surface response method to optimize the synthesis conditions of the sand control agent. The optimal synthesis conditions are obtained: total monomer concentration of 9.15 wt%, DOH concentration at 10 wt% of the total monomer concentration, ammonium sulfate (AS) concentration of 27.02 wt%, dispersant concentration of 2.13 wt%, initiator concentration at 0.25 wt% of the total monomer concentration, reaction time of 12 h, and reaction temperature of 40 °C. Under the conditions of concentration ≥2000 mg/L and curing time ≥4 h, the sand control agent is suitable for sand stabilization under formation conditions of temperatures between 50 and 80 °C, pH levels ranging from 3 to 9, salinity <30000 mg/L, and sand particle size of ≥100 μm. The research results of this paper can serve as a valuable reference for the control of oilfield sand production.
研究领域:
石油工程
·
高分子化学
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产品关联
DOI
危险品化学品经营许可证（带存储）