CHEMICAL ENGINEERING JOURNAL
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2025
·
IF 13.2
Shouhe Pan,Pengkun Yan,Rui Zhao,Fengyu Li,Lei Wang,Yinmin Wang,Ze Lv,Yingjian Ma,Meng Yu,Xinyu Guo,Yonggang Xia,Yong Xu,Xuemin Wu
Pine wood nematode disease is caused by pine wood nematodes and is difficult to prevent and control because the nematodes are located inside the trees. In this study, three types of silver nanoparticles (AgNPs) with different surface charges were prepared using Cetyl trimethyl ammonium chloride (CTAC), Polyvinyl pyrrolidone (PVP), and Acacia senegal (GA), and the ion and element concentrations in tree sap were measured after the introduction of AgNPs. Additionally, the effects of the introduction of AgNPs by foliar and soil applications and by trunk injection on the delivery of the AgNPs in the trees were compared. It was found that the LC 50 values of AgNP-GA, AgNP-PVP, and AgNP-CTAC against pine wood nematodes were 0.59, 1.15, and 1.25 mg∙L − 1 , respectively. Our toxicity mechanism studies showed that AgNP can inhibit the activity of acetylcholinesterase and catalase in pine wood nematodes, which is the main origin of the inhibition of pine wood nematode activity by AgNPs. The ion concentration of the sap has a significant impact on the delivery of AgNPs within the tree, with negatively charged AgNP-GA displaying better delivery within pine trees. In addition to conduits and sieve tubes, resin channels and intercellular spaces are likely to be the key sites for AgNP delivery. It was found that trunk injection facilitates the delivery of AgNPs within trees. This study provides an effective strategy for the prevention and control of pine wilt disease, tree trunk pests, and other diseases.
研究领域:
植物病理学
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纳米技术
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林业科学
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农药科学
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树木生理学
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生物化学
✓ 已验证
产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2024
·
IF 7.7
Yunlai Zhang,Yan Zhang,Mengqi Jian,Ying Pei,Jie Liu,Xuejing Zheng,Keyong Tang
In this work, carboxymethylated curdlan (CMCD) was utilized as a capping and stabilizing agent for the green synthesis of silver nanoparticles. Subsequently, quaternized curdlan (QCD) was introduced as the second capping layer through electrostatic attraction, leading to the preparation of double-capped silver nanoparticles (AgNPs@CQ). The successful synthesis of silver nanoparticles was characterized using UV–vis, FTIR, XRD, TEM, and DLS. AgNPs@CQ were incorporated into gelatin and a AgNPs@CQ/Gel composite hydrogel was obtained. The incorporation of AgNPs@CQ imparts excellent antibacterial properties to the composite hydrogel, thereby enhancing its antimicrobial efficacy. The presence of double-capping layers significantly retards the release rate of silver, contributing to prolonged antimicrobial activity. The MTT and live/dead fluorescence staining results demonstrate that the gelatin hydrogel incorporating double-capped AgNPs exhibits enhanced cell viability compared to the one incorporating single-capped AgNPs. Additionally, the composite hydrogel exhibits remarkable mechanical strength and adhesive performance. The AgNPs@CQ/Gel composite hydrogel demonstrates a cost-effective and facile preparation, showing significant potential in the field of dressings.
研究领域:
材料科学
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纳米技术
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生物医学工程
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药学
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产品关联
DOI
PubMed
高影响因子
ANALYTICA CHIMICA ACTA
·
2025
·
IF 6
Jiawei Li,Wei Lai,Mingsheng Tan,Mengdi Guo
Background With the advancement of technology and growing health concerns, high sensitivity, flexibility, and multi-channel detection have become crucial indicators for wearable intelligent sensors. Results Inspired by the volume contraction of hydrogels upon ethanol exposure, a strategy combining MXene with in situ reduction of silver nanoparticles has been used to construct a three-dimensional, high-sensitivity SERS substrate (MX-SNP PAH-based SERS substrate). This design not only enriches target molecules but also enables dual enhancement of charge transfer and electromagnetic enhancement by inducing inter-particle spacing between silver nanoparticles and V 2 CT x . The developed SERS substrate allows for the quantitative analysis of pesticide molecules (thiram, 1 nM), small molecules such as p-mercaptobenzoic acid (pMBA, 1 nM), and microplastics like polystyrene (PS, 6.25 μg mL −1 ). Additionally, by analyzing the sweat SERS spectra, it was possible to successfully quantify blood glucose levels (4.5 mM). Significance This innovative MX-SNP PAH-based SERS substrate design provides valuable insights for the development of flexible wearable sensors, with significant application potential in food safety, water quality analysis, and health monitoring.
研究领域:
材料科学
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纳米技术
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分析化学
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可穿戴传感器
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环境监测
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生物医学工程
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食品安全
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
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2025
·
IF 6.3
Hongzhan Chen,Binbin Sun,Jiaqi Zhang,Zhiliang Zhang,Jianbo Qu
In this work, integrated in-situ reducibility of polydopamine (PDA) with magnetic-responsive performance of ferroferric oxide (Fe 3 O 4 ) nanoparticles, a series of Fe 3 O 4 @PDA@AgNPs were engineered through in-situ grown silver nanoparticles (AgNPs) on the surface of Fe 3 O 4 nanoparticles. The synthesized Fe 3 O 4 @PDA@AgNPs could serve as superb surface enhancement Raman scattering (SERS) substrates for ultrasensitive detection of multi-component industrial dyes in the complex environment. With 4-aminothiophenol (4-ATP) as probe molecules, the Fe 3 O 4 @PDA@AgNPs demonstrated exceptional SERS sensitivity and uniformity, achieving an enhancement factor as high as 7.8 × 10 6 . Notably, the Fe 3 O 4 @PDA@AgNPs demonstrated outstanding magnetic response and molecular enrichment effect, and realized multi-component detection of Rhodamine 6 G (R6G) and Nile Blue A (NBA) molecular mixtures. The detection limit for R6G and NBA was 1 × 10⁻⁷ M and 5 × 10⁻⁷ M respectively. The magnetic Fe 3 O 4 @PDA@AgNPs represent outstanding SERS platforms, and would hold great potential in the quantitative and qualitative detection of dye molecules.
研究领域:
纳米技术
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分析化学
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材料科学
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光谱学
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环境监测
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化学传感
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
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2025
·
IF 4.6
Qian Liu,Xiaoying Yang,Longhui Luo,Wei Tian,Chao Kang,Tao Sun,Yuegang Chen,Juan Tao,Dongmei Chen
Benzimidazole fungicides are widely used in agriculture, and residues in food will threaten public health and safety. In this study, MXene@PEI@AgNPs composites were successfully constructed by electrostatic self-assembly method using polyethyleneimine (PEI) as a linker and used as a surface-enhanced Raman scattering (SERS) active substrate. The material combines the electromagnetic enhancement of silver nanoparticles and the chemical enhancement mechanism of MXene, showing excellent SERS performance. The experimental results show that the SERS substrate has excellent enhancement performance and successfully obtains the characteristic spectra of six target fungicides. After that, it was combined with chemometrics methods, through principal component analysis (PCA), it was found that the SERS spectra of different fungicides showed obvious clustering distribution. The constructed support vector machine (SVM) classification model shows excellent prediction performance, with an accuracy rate of 100 %. In terms of quantitative analysis, the method showed good sensitivity, and the detection recoveries of benzimidazole fungicides in actual samples such as kiwifruit, tomato and citrus were 81.62 % −113.87 %. Finally, in order to verify the reliability of the method, the high performance liquid chromatography (HPLC) method was used for comparative verification. The results showed that the two methods had good consistency.
研究领域:
分析化学
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食品安全
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纳米技术
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光谱学
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农业科学
✓ 已验证
产品关联
DOI
高影响因子
Nanophotonics
·
2019
·Vol. 8
·期 10
·1719-1729
·
IF 6.908
Xiaofei Zhao,Chonghui Li,Zhen Li,Jing Yu,Jie Pan,Haipeng Si,Cheng Yang,Shouzhen Jiang,Chao Zhang,Baoyuan Man
An efficient electrospun aligned surface enhanced Raman scattering (SERS) and maize-like substrate of polyvinyl alcohol (PVA) composite and Ag colloid nanofibers decorated with thermal evaporated Ag nanoparticles (AgNPs) has been developed by taking advantage of electrostatic interactions. The synergistic effects of the evaporated AgNPs (niblets) and the Ag colloid in PVA (corncob) could arouse strong electromagnetic field between the lateral and vertical nanogaps which has been demonstrated by experiment and finite-different time-domain (FDTD) simulation. In this experiment, the aligned nanofibers possesses an excellent sensitivity by detection of crystal violet (CV) and malachite green (MG) molecule at low concentration. Moreover, the proposed flexible SERS sensor was measured with outstanding uniformity and reproducibility. We also carried out in-situ electrospinning on a curved surface to detect the mixture of Sudan I, CV and MG molecule, which demonstrates that flexible SERS sensor, has enormous potential in accurate and in-situ detection on the complex geometric structure.
研究领域:
材料科学
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纳米技术
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分析化学
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表面科学
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产品关联
DOI
高影响因子
PHYSICA SCRIPTA
·
2024
·Vol. 99
·期 10
·105604
·
IF 2.6
YangTao Yuan,ZhengXian Zhou,XuDong Hao,JiaJia Mi,Yu Cao,JianPing Shi
Surface-enhanced Raman scattering (SERS) is a spectroscopic technique that utilizes nanostructured substrates and is vital in food analysis. However, enhancing SERS substrates' sensitivity and applicability remains a challenge. The conductive metal organic framework Ni3(HHTP)2 has been widely used due to its excellent conductivity and porous structure. This study combines Ni3(HHTP)2's charge transfer properties with AgNPs's localized surface plasmon resonance to create a highly sensitive SERS substrate. Firstly, rod-shaped Ni3(HHTP)2 was prepared, and then a monolayer of AgNPs film was loaded on its surface. The substrate can detect crystal violet at a concentration of 10−14 M, and Ni3(HHTP)2 has a flat structure, coupled with AgNPs film, provided good detection uniformity (Relative Standard Deviation, RSD = 10.09%). Moreover, the substrate successfully detected food additives solutions, as well as the pesticide residues on fruit surfaces by bending. This substrate offers a rapid monitoring solution for food safety, facilitating real-time detection of contaminants in daily life.
研究领域:
分析化学
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食品科学
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材料科学
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光谱学
✓ 已验证
DOI
高影响因子
Frontiers in Microbiology
·
2023
·
IF 5.2
Du Wenlong,Xu Ruolin,He Zhiqiang,Yang Huan,Gu Yufan,Liu Yi
Critically ill patients have higher risk of serious fungal infections, such as invasive aspergillosis (IA) which is mainly caused by the human fungal pathogen Aspergillus fumigatus. Triazole drugs are the primary therapeutic agents for the first-line treatment of IA, which could easily cause drug resistance problems. Here, we assess the potential of AgNPs synthesized with Artemisia argyi leaf extract and domiphen as new antifungal agents to produce synergistic antimicrobial effects on Aspergillus fumigatus, and dissect possible molecular mechanisms of action. Plate inoculation assays combined with drug susceptibility test and cytotoxicity test showed that the combination of AgNPs and domiphen has synergistic antimicrobial effects on A. fumigatus with low cytotoxicity. Gene Ontology (GO) enrichment analysis showed that AgNPs and domiphen inhibit the growth of A. fumigatus by suppressing nitrate assimilation, and purine nucleobase metabolic process and amino acid transmembrane transport, respectively. When the two drugs are combined, AgNPs has epistatic effects on domiphen. Moreover, the combination of AgNPs and domiphen primarily influence secondary metabolites biosynthesis, steroid biosynthesis and nucleotide sugar metabolism of A. fumigatus via Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analysis. Furthermore, protein–protein interactions (PPI) analysis combined with validation experiments showed that the combination of AgNPs and domiphen could enhance the expression of copper transporter and inhibit nitrogen source metabolism. In addition, the synergistic antimicrobial effects could be enhanced or eliminated depending on exogenous addition of copper and nitrogen source, respectively. Taken together, the results of this study provide a theoretical basis and a new strategy for the treatment of IA.
研究领域:
微生物学
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转录组学
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分子生物学
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抗真菌研究
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医学真菌学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
FOOD CONTROL
·
2023
·
IF 6
Chenfei Han,Yu Xiao,Zhenjiang Liu,Daolin Du,Ming Li
To improve the performance of aptasensor, the coupling of novel material and strategy had been the hottest research with the promising prospects. In this study, a cascade amplifying aptasensor (CA-aptasensor), which had coupled the DNase I-assisted cyclic enzyme digestion and AgNPs@gel-enhanced fluorescence, had reflected the desired performance for positively correlated detecting OTA . For this purpose, the GO@PVP was used to adsorb and quench the free FAM-Apt, while the complex of OTA and FAM-Apt was digested by the DNase I. The released OTA allowed the free FAM-Apt to separate from the GO@PVP cyclically, thus the OTA level was amplified preliminarily. The AgNPs@gel could combine with the released FAM to form the metal enhanced fluorescence (MEF) effect, resulting in the cascade signal amplification. The OTA was detected at pg mL −1 level with an ultrasensitive LOD of 3.33 pg mL −1 and IC 50 of 13.6 pg mL −1 , which improved 90-fold and 728-fold than that of ELASA for same aptamer. The CA-aptasensor indicated high specificity, reliability and practicability. Meanwhile, the CA-aptasensor exhibited more highlights, including the efficient homogeneous system, low background signal and standardized aptamer recognizer. This study might provide a new approach for improving the performance of aptasensor, which could also guide the signaling cascade and positively correlated detection for other risk factors.
研究领域:
分析化学
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生物传感器
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纳米技术
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食品安全
✓ 已验证
产品关联
DOI
高影响因子
BIOELECTROCHEMISTRY
·
2023
·
IF 5
Wenjing Qian,Jingming Zhou,Yumei Chen,Hongliang Liu,Peiyang Ding,Yankai Liu,Chao Liang,Xifang Zhu,Ying Zhang,Enping Liu,Aiping Wang,Gaiping Zhang
Virginiamycin (VIR), a feed additive, is used to promote pig and poultry growth. However, it is hazardous to human health. This work described a label-free electrochemical immunosensor based on silver nanoparticles-reduced graphene oxide (AgNPs-rGO) nanocomposites and staphylococcal protein A (SPA) for the first time to directly detect the residual marker VIR M1. Good catalytic currents for oxygen reduction reaction were apparently obtained after the modification of nanocomposites on gold electrode. Nanocomposites were characterized using UV–Vis, X-ray diffraction (XRD) patterns, Fourier transform infrared spectroscopy (FTIR) and transmission electron microscopy (TEM). SPA was targeted to immobilize VIR M1 monoclonal antibody (mAb) by binding to Fc region of antibody. The proposed immunosensor showed a wide linear range from 0.25 ng mL −1 to 100 ng mL −1 , providing detection limit (LOD) of 0.18 ng mL −1 of VIR M1. Recovery rates ranged from 92.27% to 98.84%, and relative standard deviation (RSD) was not above 6.6%, indicating the immunosensor could detect VIR M1 in actual samples with high accuracy. The sensor showed good selectivity, reproducibility and stability and could be considered as a potential tool for detection of VIR M1 in feed and animal derived food.
研究领域:
分析化学
·
电化学
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生物传感器
·
食品安全
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF PHYSICS D-APPLIED PHYSICS
·
2013
·Vol. 46
·期 34
·345303
·
IF 2.528
Pan Wang,Han Zhu,Shiyong Bao,MingLiang Du,Ming Zhang
Two strategies are demonstrated to fabricate AgNPs/PVA and AgNPs/(PVA/PEI) nanofibre hybrids. In the first approach, we synthesized AgNPs in poly(vinylalcohol) (PVA) solution and then electrospun the AgNPs/PVA solution into the AgNPs/PVA nanofibres. In the other one, the polyethylenimine (PEI) was introduced to improve the water-stability of PVA and then the AgNPs were immobilized on electrospun PVA/PEI nanofibres to fabricate the AgNPs/(PVA/PEI) nanofibres. Field-emission scanning electron microscopy, transmission electron microscopy, ultraviolet–visible spectroscopy and x-ray photoelectron spectroscopy (XPS) were utilized to investigate the morphology and the growth mechanism of the hybrids. The investigations demonstrate that both of the obtained AgNPs/PVA hybrids and AgNPs/(PVA/PEI) hybrids exhibit good water-stability and good antibacterial activity against E. coli and S. aureus.
研究领域:
材料科学
·
微生物学
✓ 已验证
DOI
高影响因子
Materials Science & Engineering C-Materials for Biological Applications
·
2020
·
IF 5.88
Huaxin Lv,Sisi Cui,Qianwen Yang,Xiaoyu Song,Duo Wang,Junli Hu,Yifa Zhou,Yichun Liu
Silver nanoparticles (AgNPs) have a wide antimicrobial spectrum and low incidence of resistance. They have been widely incorporated into wound dressings for antimicrobial purpose. However, these wound dressings suffer from the accompanied cytotoxicity. It is important but challenging for them to reduce the cytotoxicity without compromising antimicrobial activity, while the affecting factors are unknown. In this work, we incorporated AgNPs into starch nanofiber mats with the in situ reduction method, and investigated the structure and property of the composite nanofiber mats in detail. We found that the cytotoxicity and antibacterial activity of the starch/AgNPs composite nanofiber mats are both affected by the release behavior of silver from the mats, while of various stages and governing factors. The cytotoxicity of the mats depends on the silver release rate at the early stage, which is governed by both the size and content of the AgNPs. The antibacterial activity is more related to the silver release rate at the later stage and is determined mainly by the content of AgNPs. By optimizing the size and content of AgNPs, we found a safe window and obtained starch/AgNPs composite nanofiber mats with good antibacterial activity and excellent cytocompatibility as well. The composite nanofiber mats also showed moderate wet strength (1–2 MPa), high liquid absorption capability (19–34 times of their own weights) and suitable vapor permeability [0.22–0.26 g/(cm 2 ·24 h)]. These starch/AgNPs composite nanofiber mats are ideal candidates for the treatment of infected and exuding wounds.
研究领域:
材料科学
·
生物学
·
医学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）