CHEMICAL PAPERS
·
2022
·Vol. 76
·期 4
·2029-2039
·
IF 2.146
Tan Siwei,Ruan Xiaoying,Shao Ji,Shan Xiaoyue,Ye Haipeng,Shi Yanpeng
Self-produced peanut shell AC (activated carbon) and Al(OH) 3 (aluminum hydroxide) were successfully synthesized by ultrasound with CTAB (cetyltrimethyl ammonium bromide), and both new nanocomposite AC@Al(OH) 3 @CTAB were evaluated as adsorbents for absorption of BPA (Bisphenol A) and utilized for the determination of BPA in urine by high-performance liquid chromatography coupled with fluorescence detector. Then the AC and AC@Al(OH) 3 @CTAB nanocomposites were examined by X-ray diffraction spectra, infrared spectrum, scanning electron microscope, transmission electron microscope, X-ray photoelectron spectroscopy techniques and differential pulse voltammetry analysis. The extraction elements such as adsorption pH, time, dose, desorption solvent, elution method were also discussed. Under the optimized extraction condition, the recovery of BPA in urine sample can achieve to 99.5% when using AC@Al(OH) 3 @CTAB as the SPE (solid-phase extraction) absorbents. For the methodological analysis, the linearity was detected in the range of 0.2–50 ng mL −1 ( R 2 =0.999 3), and the limit of detection can be 0.05 ng mL −1 . Within-day and between-day relative standard deviations were less than 3.7 and 5.2%, respectively. The synthesized new nanocomposite (AC@Al(OH) 3 @CTAB) showed excellent absorptive capacity, and the proposed SPE-HPLC-FLD methodology was proved to be efficient, sensitive and operable when using AC@Al(OH) 3 @CTAB as absorbents for BPA detection in complicated biological samples.
研究领域:
环境科学
·
分析化学
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高影响因子
RESEARCH ON CHEMICAL INTERMEDIATES
·
2020
·Vol. 46
·期 6
·2951-2967
·
IF 2.262
Zheng Wei,Feng Sheng,Shao Cong,Zhu Guiliang,Ni Ziqiu,Sun Jiajia,Huang Xianglin
A novel binary photocatalytic composite (BiOI/ZIF-8) was successfully constructed by solvothermal method. Its crystal morphology, chemical state of the elements and electrochemical properties were characterized by X-ray diffraction, Fourier transform infrared spectroscopy, transmission electron microscopy, scanning electron microscopy, X-ray photoelectron spectroscopy and photoluminescence analysis. Appropriate ZIF-8 doping enhanced the separation and utilization of photogenerated electrons, promoted the capture of contaminants and rapidly produces active species, thereby accelerating the photocatalytic degradation of contaminants. Degradation experiments on BPA showed that the photocatalytic property of BiOI/ZIF-8 (0.5) was significantly improved compared with the parent material. BiOI/ZIF-8 (0.5) showed the highest reaction rate constant (0.06061 min −1 ), 9.2 times that of BiOI (0.00659 min −1 ) and 23.3 times that of ZIF-8 (0.0026 min −1 ). In addition, five cycle tests showed that BiOI/ZIF-8 was highly efficient in recycling and stability. Through capture experiments, superoxide free radicals ·OH, h − and ·O 2 − play an important role in degrading BPA, among which superoxide free radicals h + play a major role.
研究领域:
材料科学
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环境科学
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光催化技术
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高影响因子
JOURNAL OF POLYMER RESEARCH
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2026
·Vol. 33
·期 4
·163
·
IF 3.5
Wang Jing,Bai Wei,Wang Gongying,Li Chen,Wang Qingyin
Bisphenol-fluorene-type polycarbonate as a transparent thermoplastic resin, exhibits low birefringence due to the rigid fluorene. In this paper, a series of random co-polycarbonates (BPEF/BPA-PC) were prepared from bisphenol A(BPA), 9,9-bis[4-(2-hydroxyethoxy) phenyl] fluorene (BPEF) and diphenyl carbonate (DPC) using melt transesterification method by adjusting molar ratios of raw materials. The effects of catalyst dosage, polycondensation temperature and polycondensation time on the molecular weight of the products were systematically investigated, and the copolymer structures were characterized by FT-IR, 1 H NMR and 13 C NMR spectra tests; the thermal performance were determined by Differential Scanning Calorimeter (DSC) and thermogravimetric analysis. The molecular weights and their distributions( Đ ) were determined by Gel Permeation Chromatography. The results of GPC showed that the max M w of copolymers reached to 6.8*10 4 g/mol and Đ was 1.81. The maximal thermal decomposition temperature ( T d,5% ) of the co-polycarbonate reached to 359.3 °C. The refractive index of the materials was characterized using an Abbe refractometer and it showed refractive index (n d ) up to 1.640 under visible light. Mechanical property tests showed that the tensile strength of co-polycarbonate were significantly increased when the contents of BPEF was higher, reflecting the enhancement effect of fluorene unit on the rigidity of molecular chain.
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高影响因子
ACS Applied Materials & Interfaces
·
2025
·
IF 8.2
Yaxin Qin,Xiaoyan Sun,Zhicheng Zhang,Yufan Yang,Qi Dai,Xin Tan,Ruolin Jiang,Xiaoyan Bao,Linjie Wu,Changran Geng,Yuanhao Liu,Xiaoping Sun,Xingyan Liu,Minoru Suzuki,Qinchun Wei,Min Han
Glioblastoma is a highly malignant brain tumor with few available therapeutic options, for which boron neutron capture therapy (BNCT) has emerged as a promising precision radiotherapy approach. However, its efficacy remains suboptimal due to inadequate tumor targeting of boron agents and lack of in vivo visualization. Herein, a gadolinium–boron integrated lipid nanocarrier (BPA-F&DOTA-Gd@LIPO-ANG) was developed for targeted boron delivery and MRI-guided BNCT. BPA-F and DOTA-Gd were coloaded into lipid nanocarriers using a microfluidic system, with Angiopep-2 modification to enhance blood–brain barrier penetration and glioma targeting. Following cellular uptake, BPA-F&DOTA-Gd@LIPO-ANG effectively increased boron accumulation in glioma cells, inducing significant apoptosis and DNA damage upon neutron irradiation. Intravenously injected into orthotopic glioma model mice, BPA-F&DOTA-Gd@LIPO-ANG selectively accumulated in the tumor site, increasing tumor-to-normal tissue (T/N) and tumor-to-blood (T/B) ratios. Enhanced boron accumulation facilitated greater cytotoxic effects mediated by high-energy rays from the boron capture reaction, leading to significantly prolonged mice survival. In addition, in vitro and in vivo MRI validations confirmed its MRI visualization capability, meeting the demand for boron drug imaging for BNCT diagnosis and treatment integration. Overall, these results suggest that BPA-F&DOTA-Gd@LIPO-ANG is a promising targeted boron delivery system for MRI-guided BNCT in glioblastoma treatment.
研究领域:
纳米医学
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肿瘤学
·
放射治疗学
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医学影像学
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药物递送
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神经肿瘤学
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DOI
PubMed
高影响因子
Journal of Environmental Chemical Engineering
·
2026
·
IF 7.5
Yunhe Cui,Yue Tao,Hudong Fan,Ting Liu,Ying Zhang
SiO 2 @PDA-Lac achieved BPA-dominant removal with synchronous DBP reduction. • PDA-coated mesopores enhanced pollutant enrichment and laccase anchoring. • SiO 2 @PDA-Lac retained BPA/DBP removal after 5 cycles and 50 d storage. • Docking and GC-MS revealed competitive binding and divergent pathways. • ECOSAR predicted overall toxicity reduction after enzymatic transformation. The potential co-occurrence of bisphenol A (BPA) and dibutyl phthalate (DBP) in contaminated water motivates the development of treatment strategies for binary pollutant systems. Herein, a polydopamine-functionalized mesoporous silica immobilized laccase system (SiO 2 @PDA-Lac) was developed for BPA-dominant removal and synchronous DBP reduction. Immobilization time was first selected by balancing initial activity and cycling stability. With the time fixed at 6 h, immobilization pH, temperature, and laccase concentration were further optimized by RSM using relative enzyme activity as the response, yielding pH 4.0, 25 °C, and 80 mg/mL laccase. In the binary system at an initial pollutant concentration of 100 mg/L, SiO 2 @PDA-Lac removed approximately 81% of BPA and 20% of DBP. Control experiments with free laccase and inactivated SiO 2 @PDA-Lac indicated that BPA removal was driven by coupled interfacial adsorption and enzymatic catalysis, whereas DBP reduction was lower but still measurably assisted by immobilized laccase. SiO 2 @PDA-Lac retained detectable performance after five cycles, with BPA and DBP removal remaining at 57% and 14%, respectively, and maintained removal activity after 50 d of storage. Molecular docking and molecular dynamics simulations suggested that BPA and DBP may occupy partially overlapping binding microenvironments. GC-MS and ECOSAR analyses indicated possible transformation pathways with an overall tendency toward lower predicted ecological risk. These results demonstrate the feasibility of SiO₂@PDA-Lac for BPA-dominant removal and concurrent DBP reduction in a model BPA/DBP binary system. Download: Download high-res image (314KB) Download: Download full-size image
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高影响因子
APPLIED CATALYSIS B-ENVIRONMENTAL
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2021
·
IF 19.503
Zhaohui Wu,Jie Shen,Nan Ma,Zhongfu Li,Min Wu,Difa Xu,Shiying Zhang,Wenhui Feng,Yongfa Zhu
Enhancing spatial charge separation efficiency through directional charge transfer is one of the vital strategies to improve the photocatalytic performances. Bi 4 O 5 Br 2 nanosheets with vertical aligned (11−3), (32−2), and (112) facets were constructed to achieve the efficient directional charge transfer and separation based on the distinctive electronic and band structures of different facets. That is, the photoexcited electrons migrate to the top surface of (11−3) facet of the Bi 4 O 5 Br 2 nanosheets, while the holes transfer to the lateral surface of (32−2) and (112) facets. As a result, such Bi 4 O 5 Br 2 nanosheets with vertical aligned facets has highly strengthened the visible-light photodegradation efficiency of bisphenol A (BPA), which is around 6 times higher than that of BiOBr nanosheets. This work provides new sight to rational design the facets of photocatalysts for effective separation of charge carriers and promoted photocatalytic performances.
研究领域:
材料科学
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环境科学
·
纳米技术
·
光催化
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产品关联
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2020
·
IF 10.652
Mingming Zhang,Yan Gong,Ning Ma,Xu Zhao
The combination of photoelectrocatalytic (PEC) and sulfate radical (SO 4 − )-based advanced oxidation technology (SR-AOP) has been regarded as a promising technology for efficient removal of pollutants by in-situ generated reactive radicals in the field of environmental remediation. Herein, a novel PEC/SR-AOP system was constructed by employing a BiVO 4 as photoanode and a MnFe 2 O 4 modified carbon fiber paper (MnFe 2 O 4 /CFP) as cathode. The introduction of MnFe 2 O 4 greatly promotes the peroxymonosulfate (PMS) activation of CFP cathode, and the PEC process accelerates the PMS activation of MnFe 2 O 4 for the high-active SO 4 − production. As a result, the BiVO 4 -MnFe 2 O 4 /CFP system exhibited remarkably enhanced photoelectrocatalytic performances toward Bisphenol A (BPA) degradation. Nearly 100% of BPA can be degraded after 90 min irradiation under the optimal condition of 1.0 V applied bias and 1 mM PMS addition. The apparent rate constant of BPA degradation over the BiVO 4 -MnFe 2 O 4 /CFP PEC/PMS system is achieved to 0.0596 min −1 . Radical scavenger experiments and electron spin resonance confirmed that the generated OH and SO 4 − showed the responsible for BPA degradation during PEC reaction. The results of XPS and LSV tests indicated the favorable redox reaction between MnFe 2 O 4 /CFP and PMS, which results in the generation of high active SO 4 − . This work provided a promising way to synthesize other novel PEC systems with excellent photoelectrocatalytic performance for environmental pollutants removal.
研究领域:
环境科学
·
材料科学
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DOI
高影响因子
ENVIRONMENT INTERNATIONAL
·
2021
·
IF 9.621
Cuicui Guo,Feng Ren,Jing Jin,He Zhang,Longxing Wang,Haijun Zhang,Jiping Chen
Bisphenols (BPs) are widely used in consumer products, and human exposure to BPs is nearly ubiquitous. However, human biomonitoring data are scarce, especially for children. In this study, we quantified eight BPs in the serum of 345 children from a typical coastal city in China. Bisphenol A (BPA), bisphenol F (BPF), and bisphenol S (BPS) were frequently detected (63% BPA, 68% BPF, 43% BPS), with geometric mean (GM) concentrations of 1.6, 0.08, and 0.04 ng/mL, respectively. The other five BPs had low detection frequencies (<5%). The distribution of BPA, BPF, and BPS in children’s serum samples was independent of sex whereas the concentrations of BPS and BPF both significantly increased with age ( P < 0.01). The GM values of estimated daily intake for BPA and BPS were 0.61 and 0.014 μg/kg body weight (bw)/day, respectively, indicating a relatively higher exposure risk of BPA in comparison with BPS. Compared with the population with euthyroid or nonhyperthyroid thyroid dysfunction, children with hyperthyroidism suffered higher exposure to BPA. By multiple linear regression analysis, thyroid-stimulating hormone showed a significantly negative relationship with log 10 -BPA concentration for euthyroid children ( R 2 = 0.477, P < 0.001), whereas a significantly positive correlation ( R 2 = 0.753, P = 0.033) was found for hyperthyroid children.
研究领域:
环境健康
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毒理学
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内分泌学
·
公共卫生
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产品关联
DOI
PubMed
高影响因子
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
·
2024
·
IF 6.2
Kejian Tian,Jinming Gu,Yibing Wang,Fenglin Zhang,Dandan Zhou,Qing Qiu,Yue Yu,Xuejian Sun,Menghan Chang,Xinwen Zhang,Hongliang Huo
Bisphenol A (BPA) is a globally concerning toxic pollutant, and microbial degradation is considered an effective method to treat BPA contamination. However, the inherent microbial toxicity of BPA is often overlooked, particularly the microbial mechanisms of resistance and detoxification against BPA. This study found that under the toxic stress of BPA, cbb3-type cytochrome c oxidase (cbb3-Cox) in the cells of Pseudomonas asiatica P1 ( P. asiatica P1) was the first to resist the toxicity. Genes such as ccoNOQPG showed significant upregulation with an average log 2 FC value of 3.56. Subsequently, genes that are related to metal ion binding, transport, and DNA repair were upregulated in the middle to later phase, which enhanced the metabolic functions of the strains and induced strain mutations to assist P. asiatica P1 in resisting the BPA toxicity. Meanwhile, three potential BPA degradation genes were identified, among which sdr P1 was crucial to the BPA degradation and detoxification. After genetic recombination, sdr P1 achieved a degradation rate of 92.52 % for BPA. Furthermore, through various methods such as alkyl interactions, sdr P1 exhibited oxidation and demethylation to form lower toxic intermediate products and complete the biological detoxification of BPA. This study provides a systematic analysis of the toxicity resistance, biodegradation, and detoxification processes in bacterial BPA removal, refines the mechanism of BPA biodegradation and contributes to a more comprehensive and systematic understanding of the overall process of microbial removal of toxic pollutants.
研究领域:
环境微生物学
·
分子生物学
·
污染治理
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DOI
PubMed
高影响因子
Advanced Science
·
2026
·
IF 14.1
Jiyun Qi,Xinyi Hui,Xipeng Zhang,Jia-Long Wen,Tong-Qi Yuan
Epoxy resins are indispensable to structural composites, coatings, and adhesives. However, conventional bisphenol A (BPA)-based epoxy resins are limited by toxicity concerns, intrinsic brittleness, poor end-of-life recyclability, and a high carbon footprint. Here, a rigid–flexible bio-based network design is developed by coupling epoxidized soybean oil (ESO), lignin, and malic acid through maleic anhydride bridging, which simultaneously improves component compatibility and introduces dynamic ester linkages for pH-responsive degradation. The resulting thermoset achieved an unusual combination of strength, ductility, and environmental resilience, delivering 22.08 MPa shear strength as a structural adhesive and 31 4.57 MPa tensile strength in glass-fabric composites, together with an ≈250% increase in flexural strain relative to the BPA epoxy. It further maintains robust performance after exposure to chemically aggressive media and extreme temperatures ranging from −196 to 200°C. Life cycle assessment (LCA) and techno-economic analysis (TEA) confirmed its environmental friendliness and competitive cost‑effectiveness. This work demonstrates a sustainable design for high‑performance thermoset, offering a viable sustainable alternative for applications such as structural adhesives and wind‑turbine composites, thereby accelerating the transition toward a circular bio‑economy.
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产品关联
DOI
PubMed
高影响因子
Current Research in Microbial Sciences
·
2025
·
IF 5.8
Kejian Tian,Fenglin Zhang,Yibing Wang,Jinming Gu,Dandan Zhou,Fanxing Meng,Wenkang Mu,Pengfei Hao,Hongliang Huo,Fan Li
Bisphenol A (BPA) is a pervasive contaminant found in various environmental media, exhibiting extensive biotoxicity to microorganisms. Consequently, it would be of paramount significance to investigate broader methods and mechanisms for enhancing bacterial resistance to stress. This study found that BPA stress can lead to the downregulation of over 59% of functional genes and result in a maximum reduction of cell viability and ATP content in the strain. Conversely, 10 μM C6-HSL has been observed to enhance the strain's resistance to BPA toxicity stress most significantly by inducing up-regulation of genes of the pathways of antioxidant damage, amino acid synthesis and metabolism, and energy supply, and increased the cell viability by 1.13-fold. The up-regulated expression of antioxidant stress genes directly enhance the bacterial resistance to BPA toxicity, resulting in a 17.28% reduction in intracellular ROS. On this basis, C6-HSL could increase the expression levels of genes related to amino acid and energy synthesis, as well as enzyme activities. This promotes intracellular metabolic processes and energy production, ultimately elevating the ATP content within the strain by 12.21%. This study is the first to confirm the function of C6-HSL in enhancing bacterial resistance to BPA toxicity and innovatively combines Raman-DIP, transcriptomics, and enzyme activity to systematically analyse the regulatory mechanisms of C6-HSL on the bacterial antioxidant system, amino acid system, and energy system. The study provides methodological references and theoretical foundations for comprehensively enhancing the detoxification ability of microorganisms.
研究领域:
环境微生物学
·
毒理学
·
分子生物学
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代谢组学
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应激响应
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产品关联
DOI
PubMed
高影响因子
Catalysts
·
2022
·Vol. 12
·期 11
·1449
·
IF 4.501
Haiqin Lu,Guilu Xu,Lu Gan
In the present study, nitrogen doped biochar (N-PPB) and nitrogen doped activated biochar (AN-PPB) were prepared and used for removing bisphenol A (BPA) in water through activating peroxymonosulfate. It was found from the results that N-PPB exhibited superior catalytic performance over pristine biochar since nitrogen could brought about abundant active sites to the biochar structure. The non-radical singlet oxygen (1O2) was determined to be the dominant active species responsible for BPA degradation. Having non-radical pathway in the N-PPB/PMS system, the BPA degradation was barely influenced by many external environmental factors including solution pH value, temperature, foreign organic, and inorganic matters. Furthermore, AN-PPB had richer porosity than N-PPB, which showed even faster BPA removal efficiency than N-PPB through an adsorptive/catalytic synergy. The finding of this study introduces a novel way of designing hieratical structured biochar catalysts for effective organic pollutant removal in water.
研究领域:
环境科学
·
材料科学
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DOI
高影响因子
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