JOURNAL OF TOXICOLOGICAL SCIENCES
·
2019
·
IF 1.732
Yuan Chen,Xiaoxiao Fei,Chenqiao Ye,Qinqing Qian,Zhiqiu Ye,Siqi Xie,Jiamin Chen,Mingliao Zhu,Na Ran,Mingsheng Hou,Lin Xu,Zhangsen Yu
In the past few decades, upconversion nanoparticles (abbreviated as UCNPs) have been more widely applied in the biomedical fields, such as in vitro and in vivo upconversion fluorescent bioimaging, photodynamic therapy, biological macromolecular detection, imaging mediated drug delivery and so on. But meanwhile, there is still not much research on the acute toxicity of upconversion nanoparticles in vivo, such as acute hepatotoxicity. In this work, we studied the in vivo biodistribution and acute hepatotoxicity of multimodal targeted contrast agent NaLuF4:Gd,Yb,Er-PEG/PEI-FA nanoprobe, which were synthesized by the solvothermal method and modified with Polyethylene glycol (PEG), Polyetherimide (PEI), folic acid (FA) on the surface. The acute hepatotoxicity in mice was systematically assessed after tail vein injection of different concentration of UCNPs. The results showed that NaLuF4:Gd,Yb,Er-PEG/PEI-FA nanoparticles with an average diameter of 44.5 ± 10.4 nm, and three typical upconversion fluorescence emission bands at 520 nm, 540 nm and 660 nm under the excitation of 980 nm laser. In vivo distribution experiments results demonstrated that approximately 87% of UCNPs injected through the tail vein accumulate in the liver. In the acute hepatotoxicity test, the intravenously injection dose of UCNPs was 10, 40, 70 and 100 mg/kg, respectively. The body weight, blood routine, serum biochemistry, histomorphology and liver oxidative stress were detected and observed no significant acute hepatotoxicity damage under the injection dose of 100 mg/kg. In conclusion, NaLuF4:Gd,Yb,Er-PEG/PEI-FA nanoprobes are safe and reliable, and have potential applications in the field of tumor targeted multimodal imaging.
研究领域:
生物医学工程
·
毒理学
·
纳米技术
·
分子影像
✓ 已验证
DOI
PubMed
高影响因子
RSC Advances
·
2018
·Vol. 8
·期 18
·9611-9617
·
IF 2.936
Ji-Wei Shen,Zhiqing Wang,Xiaoxuan Wei,Jiawei Liu,Yinmao Wei
Herein, user-friendly control of the synthesis of sub-10 nm hexagonal (β-) NaYbF4:Er nanocrystals (NCs) with extremely low-level Gd3+ doping (0%, 10 mol%) was achieved. We reveal for the first time that the effective sodium/fluoride levels during the formation of cubic (α-) nuclei are not only controlled by the sodium/fluoride to rare-earth precursor ratios used, but also sensitively restricted by the in situ NaF generation reaction in a sodium oleate-based solvothermal system. Excessive in situ NaF generation will lead to a respective sodium- and fluoride-deficient environment, delayed α-to-β transition and larger β-NCs. Based on these effects, sub-10 nm monodisperse low-level Gd3+-doped β-NaYbF4:Er was obtained with a user-friendly low fluoride dosage by finely balancing this NaF generation reaction and achieving an intrinsic optimized sodium-fluoride level for NC nucleation. Notably, our work represents the first example where the focus is on the competing in situ NaF generation reaction and its use for nucleation regulation, as well as for the user-friendly control of the solvothermal synthesis of sub-10 nm β-NaYbF4:Er.
研究领域:
材料科学
·
纳米技术
✓ 已验证
DOI
PubMed
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2024
·
IF 5.8
Guangliang Lu,Rao Qin,Dabiao Zhai,Tianqi Wan,Jiangang Jiang,Dan Zhang,Ping Zhang,Yiping Wang,He Wang
The development and comparison of Latent Fingerprint Patterns (LFPs) constitute critical components of research in fingerprint detection and identification. However, the development of nanomaterials visualization and digital algorithms for LFPs analysis are mostly studied independently, resulting in inaccurate LFPs. This research synthesized a series of efficient red-emitting NaYF 4 :20 %Yb, 2 %Er, x %Mn ( x = 0, 5, 10, 15, 20, 25, 30, 35, and 40) upconversion nanoparticles (UCNPs) for image development, which were combined with a digital algorithm for accurate LFP recognition. The eightfold increase in luminescence intensity of NaYF 4 :Yb, Er, 30 %Mn at 653 nm effectively avoids interference from biological tissue fluorescence. This improvement is credited to the efficient reverse energy transfer mechanism between Er 3+ and Mn 2+ ions, specifically the transition sequence 4 S 3/2 (Er 3+ ) → 4 T 1 (Mn 2+ ) → 4 F 9/2 (Er 3+ ). Furthermore, a MATLAB program was employed to process the fluorescent images of LFPs developed using the UCNPs nanophosphors, achieving a high matching score of 90.09 % for the optimized sample, significantly outperforming traditional benchmarks. These results demonstrate the superior effectiveness of the NaYF 4 :Yb, Er, 30 %Mn nanophosphor, combined with digital processing algorithms, for practical LFP recognition applications.
研究领域:
材料科学
·
生物医学工程
·
人工智能
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
·
2019
·Vol. 30
·期 12
·11043-11053
·
IF 2.195
Zheng Jianfeng,Deng Xueshuang,Zhou Xin,Yu Meidong,Xia Zhetao,Chen Xiaohong,Huang Sumei
We report a strategy to fabricate high quality TiO 2 nanrod array ETLs for efficient PSC devices with Cs 0.05 (MA 0.17 FA 0.83 ) 0.95 Pb(I 0.83 Br 0.17 ) 3 triple cation composition perovskite as light absorption material. Mg doped compact TiO 2 (c-TiO 2 ) was employed as seeds for hydrothermal growth of one-dimensional (1D) TiO 2 nanorod (NR) arrays. Assisted with these seed layers, Mg and Er doped TiO 2 rutile NR arrays were synthesized using tetrabutyltitanate (TBT) and Er(NO 3 ) 3 as Ti and Er precursors, respectively. It was found that uniform, straight and vertical TiO 2 NRs with a high area density were formed using Mg and Er co-modification, improving the pore-filling and crystallization of the triple cation perovskites, facilitating charge separation and suppressing recombination at the perovskite/titania NR interface of the PSC device. The shorter PL decay time with Mg/Er doping compared to the cases without Mg or Er doping is assigned to the more excellent electron extraction from the mixed cation perovskite film. The control device without modification shows an average power conversion efficiency (PCE) of 17.10%. Under the same fabrication conditions, doping of the single element Er or Mg or both Mg and Er enhances the average PCE to 17.54, 18.41 and 18.99% respectively. Our champion cell based on Mg/Er modified TiO 2 NR arrays demonstrates a PCE of 19.11%, exhibiting an enhancement of 10.33% compared with that of the PSCs based on unmodified TiO 2 NR arrays (17.32%). This work provides a simple and efficient interface engineering method to improve the efficiency of the mixed cation PSCs.
研究领域:
材料科学
·
能源技术
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2020
·
IF 4.65
Jingxiao Liu,Zhichun Zou,Fei Shi,Xin Song,Haoyuan Zhang,Han Zhang,Xiaoying Song,Xinran Zhao,Zixuan Wang,Jiahong Kang
In order to further improve the luminescence of NaYF 4 :Yb,Er, we successfully constructed pitaya-like Cs 0 · 3 WO 3 @NaYF 4 :Yb, Er particles, in which Cs 0 · 3 WO 3 particles were encapsulated in NaYF 4 :Yb, Er particles. This structure enhanced the intensity of 407, 527, 542 and 657 nm emission peaks by 10.1, 5.9, 5.5 and 1.8 times, respectively. Through calculated, the Commission Internationale de l’Eclairage (CIE) chromaticity coordinates changed from (0.28, 0.71) to (0.25, 0.73), indicating that the emission colour was tuned from yellow to green. The construction mechanism of this structure and the mechanism of upconversion (UC) luminescence enhancement were discussed. By studying the different luminescence mechanisms of NaYF 4 :Yb, Er excited by 1550 and 980 nm laser, we found that the UC luminescence enhancement and colour tuning of NaYF 4 :Yb, Er were due to the localized surface plasmon resonance (LSPR) effect of Cs 0 · 3 WO 3 , which can absorb more excited photons and transfer them to the Er 3+ ion 4 I 11/2 level. Given that the transition process of green light emission is easier than red light emission, the redundant photons are more inclined to achieve emitting green light and show UC luminescence enhancement and emission colour tuning. Overall, the as-prepared novel pitaya-like Cs 0 · 3 WO 3 @NaYF 4 :Yb, Er particles exhibit strong UC luminescence enhancement and colour tuning, thus having great application prospect in the field of luminescent displays.
研究领域:
材料科学
·
光学
✓ 已验证
产品关联
DOI
高影响因子
CERAMICS INTERNATIONAL
·
2024
·
IF 5.1
Linjia Hu,Ruite Liu,Wenkai Zhao,Zaiyang Wang,Feng Guan,Yuchen Wang,Longfei Zhang,Yiguang Jiang,Long Zhang
Perfluoride glass ceramics (FGCs) with SrF 2 /CaF 2 mixed crystals were prepared using a concurrent rapid-quenching-crystallization process. The FGCs contained dense, homogeneous, round crystals of sizes less than 1 μm with high transmittance (exceeding 80 % at 3–8 μm) and low phonon energy (508 cm −1 ). The fluorescence properties of the FGCs doped with Er and Dy were investigated. The energy transfer efficiency between Er and Dy reached 93.81 % and 98.13 %, corresponding to Er: 4 I 11/2 to Dy: 6 H 5/2 and Er: 4 I 13/2 to Dy: 6 H 11/2 , respectively. This enhancement is attributed to the enrichment of rare-earth ions in the crystals induced by phase-separation and low phonon energy of the host material, FGC. Moreover, the average lifetime of Er: 4 I 11/2 in FGC reached 10.13 ms, which is the highest reported value for glass ceramics to our knowledge. This study enriches the research theory of FGC and provides guidance for expanding the properties of materials for mid-infrared photonics.
研究领域:
材料科学
·
光学
✓ 已验证
DOI
高影响因子
RSC Advances
·
2014
·Vol. 4
·期 84
·44575-44582
·
IF 3.708
Peng Jing,Qin Wang,Baocang Liu,Guangran Xu,Yanbing Zhang,Jun Zhang,Gejihu De
We develop a facile layer-by-layer deposition process to create bi-functional Fe3O4@SiO2@Gd2O3:Yb,Er nanostructures composed of magnetic Fe3O4 cores, variable SiO2 mid-layers, and up-converting Gd2O3 shells. The synthetic process is well-controlled and the obtained Fe3O4@SiO2@Gd2O3:Yb,Er nanoparticles show relative monodispersity and exhibit tunable magnetic and up-conversion luminescence depending on the thickness of SiO2 mid-layers. The influences of SiO2 mid-buffer-layers on morphology, magnetism, and up-conversion luminescence are well addressed. The obtained bi-functional Fe3O4@SiO2@Gd2O3:Yb,Er nanoparticles may be potentially applicable in magnetic, fluorescent, and biological applications. The synthetic route may be employed for fabricating other multifunctional nanostructures.
研究领域:
材料科学
·
生物医学工程
·
纳米技术
✓ 已验证
产品关联
DOI
高影响因子
MATERIALS RESEARCH BULLETIN
·
2018
·
IF 2.873
Zhilai Li,Omar Johnson,Jin Huang,Ting Feng,Chaoqing Yang,Zhongxin Liu,Wei Chen
Graphene oxide/NaYF 4 : Yb, Er nanocomposites have been synthesized via hydrothermal synthesis, in which spherical cubic phase NaYF 4 : Yb, Er nanocrystals with uniformity are implanted onto the surface of graphene oxide (GO). Using a near infrared laser set to 980 nm, the light-to-heat energy transfer efficiency of GO/NaYF 4 : Yb, Er is 13.9% higher than GO by itself, revealing that the photothermal conversion efficiency of GO could be enhanced by doping NaYF 4 : Yb, Er nanocrystals. This phenomenon can be attributed to the energy transfer between the NaYF 4 : Yb, Er nanocrystals to the energy receptor in the GO substrate.
研究领域:
材料科学
·
光学
✓ 已验证
产品关联
DOI
高影响因子
APPLIED SURFACE SCIENCE
·
2024
·
IF 6.3
Jun Yu,Hao Yang,Xiangyu Li,Xupeng Chen,Wenyue Li,Xingang Li,Chun Zhang
Semiconductor photocatalytic technology is recognized as one of the effective technologies for using solar energy to solve current environmental problems. In this study, a Z-scheme heterojunction ZnFe 2 O 4 /Er-ZnO hollow nanotube composite was prepared by hydrothermal method. The results show that the degradation efficiency of tetracycline (TC) in ZnFe 2 O 4 is only 51 %, while the degradation efficiency of ZnFe 2 O 4 /2% Er-ZnO hollow tube composites is as high as 97 %. At the same time, ZnFe 2 O 4 /2% Er-ZnO has a larger specific surface area (specific surface area of 224.39 m 2 · g −1 ), which is 27 times that of ZnFe 2 O 4 (specific surface area of 8.30 m 2 ·g −1 ). Density functional theory (DFT) calculations and experimental analysis show that the doping of Er, the unique hollow structure and the formation of heterojunction make ZnFe 2 O 4 /2% Er-ZnO have a large specific surface area, efficient carrier separation ability and strong redox ability, so the Z-scheme heterojunction ZnFe 2 O 4 /2% Er-ZnO hollow tubular composites have strong degradation ability for tetracycline. In addition, the liquid chromatography-mass spectrometry (LC-MS) analysis technique was used to propose the possible degradation pathways of antibiotics, which provided ideas for the treatment of water pollution.
研究领域:
环境科学
·
材料科学
·
化学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
·
2025
·Vol. 37
·期 1
·14
·
IF 2.8
Li Yonghang,Su Fuyan,Cai Qingfeng,Guo Hui,Chai Xiaona,Zou Hua
Yb and Re (Re = Er, Ho) codoped Sr₂ScSbO₆ double perovskite phosphors were synthesized via high-temperature solid-state reaction. Under excitation by a 980 nm laser, the Yb 3 ⁺/Er 3 ⁺ codoped sample exhibits weak green emissions at 522 and 558 nm, along with a dominant red emission at 660 nm, which is attributed to efficient cross-relaxation processes that enhance population of the 4 F 9/2 level. Notably, the emission intensities are temperature-dependent, resulting in distinct and visible changes in emission color with increasing temperature. Temperature sensing based on the fluorescence intensity ratio (FIR) demonstrates a maximum relative sensitivity of 0.73% K⁻ 1 at 490 K and an absolute sensitivity of 1.43% K⁻ 1 at 730 K. In contrast, the Yb 3 ⁺/Ho 3 ⁺ codoped sample exhibits dual green (543 nm) and red (661 nm) emissions, along with superior performance in high temperatures, achieving a relative sensitivity of 0.59%·K⁻ 1 and an absolute sensitivity of 0.42%·K⁻ 1 at 670 K. These results suggest that the Yb 3 ⁺/Er 3 ⁺ system is more suitable for low-to-intermediate temperature sensing, while the Yb 3 ⁺/Ho 3 ⁺ system is better suited for high-temperature optical thermometry applications.
研究领域:
材料科学
·
无机化学
·
功能材料
·
光学材料
·
传感器技术
·
固体物理
✓ 已验证
产品关联
DOI
高影响因子
CRYSTENGCOMM
·
2015
·Vol. 17
·期 31
·5900-5905
·
IF 4.034
Bin-Bin Ding,Kun Liu,Fu Zhang,Yang Wang,Sheng Cheng,Yang Lu,Hai-Sheng Qian
Upconversion fluorescent nanostructures with controlled sizes and morphologies have attracted much attention due to their potential and important applications in bioimaging, photodynamic therapy, solar cells and so on. In this work, we describe a facile successive process to fabricate β-NaGdF4:Yb,Er nanocrystals coated with an ultrathin layer of CaF2 with enhanced upconversion fluorescence and stability. The as-prepared β-NaGdF4:Yb,Er@CaF2 nanoparticles were investigated by X-ray diffraction (XRD), transmission electron microscopy (TEM, JEM 21000), fluorescence spectroscopy (Hitachi High-Technology Corporation, F-2700) and inductively coupled plasma atomic emission spectroscopy (ICP-AES). The as-prepared core–shell nanoparticles show enhanced upconversion fluorescence and superior magnetic resonance (MR) relaxivity. In addition, the as-prepared β-NaGdF4:Yb,Er@CaF2 nanoparticles show enhanced chemical stability after surface functionalization and transfer into aqueous solutions.
研究领域:
材料科学
·
生物医学工程
·
纳米技术
✓ 已验证
产品关联
DOI
高影响因子
ACS Applied Materials & Interfaces
·
2025
·
IF 8.2
Guibin Zhang,Xin Wang,Yaqian Du,Jun Wang,Xuebing Yang,Ta La,Jianbo Li
SrTiO3 exhibits promising potential in both thermoelectric and optical properties. However, research on these two properties has consistently been carried out in two relatively independent fields. In this work, the regulatory mechanisms of thermoelectric and optical properties were proposed based on photon-excited electron–phonon interactions. Er doping can enhance the photon absorption of SrTiO3 by introducing impurity energy levels, thereby promoting photoexcited electron generation. The introduction of oxygen vacancies (Vo) enhances the interaction between excited electrons and phonons through defect levels, facilitating the conversion of photon energy into thermal energy and subsequently into electrical energy. Additionally, Er–Nb codoping with Vo synergistically optimizes thermoelectric properties, thereby laying a foundation for the regulation of photothermoelectric properties. As a result, significant photothermoelectric conversion was obtained in the Sr0.85Er0.15Ti0.9Nb0.1O3 (Vo) sample. A maximum ZT value of 0.32 at 1073 K was achieved in this sample, representing a 60% improvement over previously reported Nb-doped SrTiO3 samples. The electrical output power of the Sr0.85Er0.15Ti0.9Nb0.1O3 (Vo) sample reaches 3.85 μW under portable 980 nm laser excitation at 260 mW incident power. These findings provide valuable insights into the conversion of light energy to electrical energy in highly absorptive SrTiO3-based thermoelectric materials.
研究领域:
材料科学
·
热电学
·
光电子学
·
能量转换
·
固体物理
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）