JOURNAL OF APPLIED POLYMER SCIENCE
·
2023
·Vol. 140
·期 45
·e54657
·
IF 3
Xuefei Chen,Yi Wang,Qianqian Zhang,Jie Meng,Tiandi Pan,Huaizhong Xu,Lei Du,Xiaohua Yang
The synergistic antibacterial effect of photothermal and drug treatments is a promising therapeutic method for treating the persistent bacterial infection of chronic wounds. In this study, we used electrospinning to fabricate functionalized poly(ε-caprolactone) (PCL) nanofiber membranes as antibacterial wound dressings after incorporating tannic acid (TA) and ferric ion (Fe 3+ ). The abilities of pH-responsive controlled release TA and the photothermal effect of the membrane were obtained by introducing the TA/Fe 3+ complexes. Additionally, the membrane had a defined nanofibrous network structure, excellent mechanical properties, hydrophilicity, and water uptake ability. While the controlled release of TA endowed the membrane with high antibacterial properties at different pH values, the antibacterial ratio was further enhanced by approximately 10% under the photothermal synergistic effect. These results indicate that the PCL/TA/Fe 3+ nanofiber membranes could be regarded as an ideal candidate for treating bacterial infection of chronic wounds.
研究领域:
材料科学
·
纳米技术
·
生物医学工程
·
伤口愈合
✓ 已验证
产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2024
·
IF 7.7
Ying Yuan,Zhiqiang Tang,Zhihao Yang,Xiluan Wang
Functional hydrogel sensors have shown explosive growth in the health and medical fields. However, the uniform adhesion and the complicated polymerization process of hydrogels seriously hinder their further development. Herein, inspired by the layered structure of human skin, we prepare a Janus gel using in-situ polymerization. Based on the lignin-Fe 3+ dual catalytic system, the rapid polymerization of the gel was achieved at room temperature. By tailoring the mass ratio of lignin and Fe 3+ in the precursor, the adhesion of the upper and bottom layers can be easily adjusted. In addition, hydrophobic association is introduced into the upper layer to improve the gel's mechanical properties. The obtained asymmetric bilayer gel has a significant difference in adhesion (7 times), and exhibits excellent mechanical properties in the elongation at break (1437 %) and the breaking strength (463.2 kPa). Moreover, the bilayer gel also has good freezing and UV resistance. We use the bilayer gel as a wearable strain sensor, which shows a wide strain detection range of 0–800 % (maximum gauge factor = 5.3). The proposed simple strategy avoids UV irradiation and heating processes, which provides a new idea for the rapid polymerization of multifunctional Janus hydrogels with adjustable performances.
研究领域:
材料科学
·
化学工程
·
生物医学工程
·
传感器与执行器
✓ 已验证
DOI
高影响因子
FOOD CHEMISTRY
·
2024
·
IF 8.5
Yiyang Chai,Ying Zhou,Kai Zhang,Ping Shao
Resveratrol (RES) is an important functional substance with multiple active properties. However, RES is susceptible to natural environmental conditions that reduce its bioactivity. To improve the bioavailability of RES, in this study, Catechin and Fe 3+ /Ca 2+ were selected to form supramolecules, which were then coated on the surface of hydrophobic RES nanoparticles (RES NPs) to create composite RES NPs. The obtained composite RES NPs demonstrated higher antioxidant capacity and better photo-thermal stability than RES NPs. Additionally, a pectin (PE) dietary gel was designed as a delivery carrier for RES. The results showed that the incorporation of composite RES NPs not only endowed the gels with significant dietary activity but also enhanced the texture, water retention capacity and hydrophobicity. After 28 days of storage, the retention rate of RES could be maintained above 90 % in the dietary gels. Meanwhile, the controlled release of RES was achieved in in vitro simulated digestion.
研究领域:
药学
·
食品科学
·
纳米技术
·
材料科学
✓ 已验证
DOI
PubMed
高影响因子
ADVANCED FUNCTIONAL MATERIALS
·
2021
·Vol. 32
·期 15
·2111278
·
IF 18.808
Haiyan Feng,Yanfei Ma,Zhizhi Zhang,Song Yang,Zhengfeng Ma,Yunlei Zhang,Shuanhong Ma,Bo Yu,Meirong Cai,Xiaowei Pei,Feng Zhou
Hydrogels, exhibiting wide application prospects in soft robotics, tissue engineering, implantable electronics, etc., upon functioning often require to adhere to substrates especially in wet environments despite that most hydrogels are nonsticky because of their high water content and hydrophilicity. Herein, a strategy to rapidly reverse the adhesion properties of hydrogels via surface anchoring very thin adhesive coatings is reported. Inspired by mussel adhesion, poly(vinyl alcohol) hydrogel is first coated with polymerized tannic acid that chelates with Fe 3+ , which serves as the interface bonding layer. Subsequently, a wet adhesive poly(dopamine methacrylamide- co -methoxyethyl acrylate) is firmly anchored to form the very thin adhesive coating (<10 µm) that can generate high adhesion strength both in the air and underwater. The adhesive coating also endows hydrogels with high water retention capacity under warm condition (50 °C) and is able to get on-demand functionalization on the designated area to achieve asymmetric adhesion, static and dynamic control over wettability. The strategy demonstrates potentials for broad applications from biomedicine to wearable electronics.
研究领域:
材料科学
·
生物医学工程
·
软体机器人
·
组织工程
·
可穿戴电子设备
✓ 已验证
DOI
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2024
·
IF 8.1
Hui Wen,Lizhu Liang,Nuanyuan Xu,Changkun Liu
Removing oil pollution from seawater prior to its desalination helps in saving time and cost. In this study, a novel superhydrophobic cotton fabric with photothermal effect and self-cleaning property was prepared via the incorporation of Fe 3+ -polydopamine (PDA) coating and carbon nanotubes (CNTs) on the fabric surface (termed as CF@PDA/CNT), followed by the grafting of (3-glycidyloxypropyl)trimethoxysilane (GPTMS) and octadecylamine (ODA) (termed as the CF@PDA/CNT-GPTMS-ODA). CF@PDA/CNT exhibits good desalination with photothermal conversion capability on the high-salinity water (evaporation rate > 1.11 kg/(m 2 ⋅h)), providing an effective basis for the preparation of the photothermal-assisted oil–water separator (CF@PDA/CNT-GPTMS-ODA), with which the crude oil permeation time was improved from 58 s without light to only 9 s with light, showing the pronounced contribution of the photothermal effect on the oil permeation. In addition, CF@PDA/CNT-GPTMS-ODA used in the form of oil skimmer and underwater oil absorbent demonstrates excellent oil–water separation performance (separation efficiency > 97 %). Notably, the fabric can isolate various oil phases from both pure water and simulated seawater, with separation efficiencies exceeding 97 %. This novel material offers a promising solution for addressing complex water pollution issues and introduces a potential approach for integrating photothermal conversion effect into the field of oil–water separation.
研究领域:
材料科学
·
环境工程
·
纳米技术
·
化学工程
✓ 已验证
产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2024
·
IF 7.7
Chen Tang,Tuhe Shi,Guohua Xu,Jingbo Yin,Shifeng Yan,Xiaogang Bao
Acquiring rapid and effective hemostasis remains a critical clinical challenge. Current researches focus on concentrating blood components to speed up the hemostatic while ignore the effect of anti-fibrinolysis in promoting blood coagulation. Herein, we designed a novel tranexamic acid (TA)-loaded physicochemical double cross-linked multifunctional catechol-modified hyaluronic acid-dopamine/carboxymethyl chitosan porous gel micropowders (TA&Fe 3+ @HA-DA/CMCS PGMs) for rapid hemostasis and wound healing . TA&Fe 3+ @HA-DA/CMCS PGMs exhibited high water absorption rate (505.9 ± 62.1 %) and rapid hemostasis (79 ± 4 s) in vivo . Catechol groups, Fe 3+ and the protonated amino groups of CMCS induced bacterial death. Moreover, TA&Fe 3+ @HA-DA/CMCS PGMs displayed sufficient adhesion to a variety of wet rat tissues. TA&Fe 3+ @HA-DA/CMCS PGMs on various bleeding wounds , including rat liver injury and tail severed models showed excellent hemostasis performance. The TA&Fe 3+ @HA-DA/CMCS PGMs could promote the healing of full-thickness skin wounds on the backs of rats. The advantages of TA&Fe 3+ @HA-DA/CMCS PGMs including rapid hemostasis, effective wound healing, good tissue adhesion , antibacterial properties and ease of use make it potentially valuable in clinical application.
研究领域:
生物材料
·
止血
·
伤口愈合
·
生物医学工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Journal of Environmental Chemical Engineering
·
2021
·
IF 5.909
Hongyu Zeng,Ping Wang,Lizhu Liang,Hao Hu,Ye Peng,Xuelian Li,Changkun Liu
In recent years, offshore oil leakage incidents have occurred relatively frequently and it has been a challenge to effectively recover the oil due to its high viscosity. Herein, a novel superhydrophobic cotton fabric with a photothermal conversion effect for efficient separation of crude oil was prepared by a facile and inexpensive vapor deposition method. After the cotton fabric adsorbs Fe 3+ ions, stearic acid (SA) with low surface energy is introduced into the fabric. Then the pyrrole monomers were polymerized to polypyrrole (PPy) by Fe 3+ ions through vapor deposition method to obtain a fabric with photothermal properties and superhydrophobicity. The modified fabric showed good abrasion resistance , acid/alkali resistance, and self-cleaning properties. In addition, the modified fabric exhibited excellent photothermal conversion performance, and its surface temperature was able to increase from 30.0 °C to 59.5 °C in 2 min, and reached 68.2 °C in 5 min under simulated sunlight. Finally, three kinds of oil-water separation methods were adopted to separate oil from water with different viscosities, and all of them showed high separation efficiency, with the maximum reaching 99.4%. Under the simulated sunlight, the modified fabric could reduce the crude oil viscosity through photothermal conversion effect, so as to improve the efficiency of selectively absorbing crude oil from water, which increased from 83.2% to 91.8%.
研究领域:
材料科学
·
环境科学
·
化学工程
✓ 已验证
DOI
高影响因子
Nano Research
·
2021
·Vol. 15
·期 2
·1509-1516
·
IF 8.897
Ye Xinhui,Li Yu,Luo Peipei,He Bingcai,Cao Xinxing,Lu Tongbu
Sunlight-driven activation of molecular oxygen (O 2 ) for organic oxidation reactions offers an appealing strategy to cut down the reliance on fossil fuels in chemical industry, yet it remains a great challenge to simultaneously tailor the charge kinetics and promote reactant chemisorption on semiconductor catalysts for enhanced photocatalytic performance. Herein, we report iron sites immobilized on defective BiOBr nanosheets as an efficient and selective photocatalyst for activation of O 2 to singlet oxygen ( 1 O 2 ). These Fe 3+ species anchored by oxygen vacancies can not only facilitate the separation and migration of photogenerated charge carrier, but also serve as active sites for effective adsorption of O 2 . Moreover, low-temperature phosphorescence spectra combined with X-ray photoelectron spectroscopy (XPS) and electronic paramagnetic resonance (EPR) spectra under illumination reveal that the Fe species can boost the quantum yield of excited triplet state and accelerate the energy transfer from excited triplet state to adsorbed O 2 via a chemical loop of Fe 3+ /Fe 2+ , thereby achieving highly efficient and selective generation of 1 O 2 . As a result, the versatile iron sites on defective BiOBr nanosheets contributes to near-unity conversion rate and selectivity in both aerobic oxidative coupling of amines to imines and sulfoxidation of organic sulfides. This work highlights the significant role of metal sites anchored on semiconductors in regulating the charge/energy transfer during the heterogeneous photocatalytic process, and provides a new angle for designing high-performance photocatalysts.
研究领域:
材料科学
·
催化
·
光化学
·
有机合成
✓ 已验证
产品关联
DOI
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2020
·
IF 5.774
Hengrao Liu,Guanhua Liu,Min Zhang,Hao Zhao,Yanjun Jiang,Jing Gao
Tannic acid (TA) is a promising material to prepare nanofiltration membranes due to its multiple interaction abilities with metal ions and zwitterionic polymer via coordination interaction and electrostatic interaction, respectively. Herein, we proposed a multiple layer-by-layer (mLBL) assembly strategy using three assembly materials for the rapid preparation of TA based zwitterionic nanofiltration membranes with enhanced antifouling performance, which was compared with the non-zwitterionic nanofiltration membranes prepared via the conventional layer-by-layer (cLBL) assembly. Among a series of transition metal ions, Fe 3+ was chosen to prepare nanofiltration membranes. The ATR-FTIR and XPS analysis revealed the TA/Fe 3+ layer was formed and the poly(sulfobetaine methacrylate) (PSBMA) polymer was successfully assembled on membrane surface. The prepared zwitterionic nanofiltration membranes showed enhanced hydrophilicity, roughness and zeta potential than the non-zwitterionic nanofiltration membranes. The influence of TA/Fe 3+ bilayer number and PSBMA concentration on membrane performance was systematically studied and the rejection properties of the prepared membranes for dyes and salts were also investigated. Under the optimum preparation condition, the zwitterionic (TA/Fe 3+ ) 1.5 /PSBMA membrane showed water permeability of 40.36 LMH/bar with rose bengal (RB) rejection more than 98% and Na 2 SO 4 rejection about 60%. Because of the introduction of the PSBMA polymer, the zwitterionic (TA/Fe 3+ ) 1.5 /PSBMA membrane showed better antifouling performance than non-zwitterionic (TA/Fe 3+ ) 2.5 membrane with similar rejection properties.
研究领域:
材料科学
·
膜技术
·
环境工程
·
化学工程
✓ 已验证
产品关联
DOI
高影响因子
MATERIALS & DESIGN
·
2024
·
IF 7.6
Pei Gong,Lulu Ren,Xinghui Gao,Jie Long,Weidong Tian,Min He
Local oxidative stress induced by surgical trauma has been recognized as one of pathogenesis for postsurgical adhesion tissue formation. Herein, tannic acid (TA) based metal-phenolic networks (MPNs) was assembled via chelating with Fe 3+ , and acted as a novel bio-filler for nanofibrous polycaprolactone (PCL) barrier membrane to endow it with reactive oxygen species (ROS) scavenging capacity. By chelating with Fe 3+ , the release of TA could last for more than 20 days, rendering the membrane with continuous ROS scavenging capacity. The modified membrane could effectively inhibit fibroblasts adhesion and proliferation, as well as immune cells recruitment, infiltration, and expression of pro-inflammatory cytokines. Consequently, a complete prevention of peritoneal adhesion formation was obtained in a rat model of sidewall defect-cecum abrasion, far better than commercial Poly lactic acid (PLA) membrane. Systematic biological mechanism investigations revealed that the enhanced anti-adhesion function was mainly ascribed to its robust ROS scavenging capacity, through which the PI3K-Akt signaling pathway was blocked, leading to repress of downstream NF-κB-TGFβ1-SMAD signaling pathway, finally inhibiting the bioactivity of fibroblasts and immune cells. This work provided a new strategy for the design of advanced barrier membrane, demonstrated its efficacy and mechanism on preventing postoperative adhesion, holding great promise for future clinical application.
研究领域:
生物医学工程
·
材料科学
·
外科手术
·
药理学
✓ 已验证
产品关联
DOI
高影响因子
Nature Communications
·
2023
·Vol. 14
·期 1
·1-13
·
IF 16.6
Chen Na,Du Na,Shen Ruichen,He Tianpei,Xi Jing,Tan Jie,Bian Guangkai,Yang Yanbing,Liu Tiangang,Tan Weihong,Yu Lilei,Yuan Quan
Microbial communication can drive coordinated functions through sensing, analyzing and processing signal information, playing critical roles in biomanufacturing and life evolution. However, it is still a great challenge to develop effective methods to construct a microbial communication system with coordinated behaviors. Here, we report an electron transfer triggered redox communication network consisting of three building blocks including signal router, optical verifier and bio-actuator for microbial metabolism regulation and coordination. In the redox communication network, the Fe 3+ /Fe 2+ redox signal can be dynamically and reversibly transduced, channeling electrons directly and specifically into bio-actuator cells through iron oxidation pathway. The redox communication network drives gene expression of electron transfer proteins and simultaneously facilitates the critical reducing power regeneration in the bio-actuator, thus enabling regulation of microbial metabolism. In this way, the redox communication system efficiently promotes the biomanufacturing yield and CO 2 fixation rate of bio-actuator. Furthermore, the results demonstrate that this redox communication strategy is applicable both in co-culture and microbial consortia. The proposed electron transfer triggered redox communication strategy in this work could provide an approach for reducing power regeneration and metabolic optimization and could offer insights into improving biomanufacturing efficiency.
研究领域:
生物技术
·
微生物学
·
生物工程
·
合成生物学
·
代谢工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2024
·
IF 7.7
Ke Deng,Qin Huang,Xiaotong Yan,Yan Dai,Juan Zhao,Xia Xiong,Hailan Wang,Xianggui Chen,Pengfei Chen,Li Liu
Achieving the controllable detachment of polysaccharide-based wound dressings is challenging. In this study, a novel, photodetachable salecan-based hydrogel dressing with injectable, self-healing, antibacterial, and wound healing properties was developed using a green and facile approach. A salecan hydrogel with a uniform porous structure and water content of 90.4 % was prepared by simply mixing salecan and an Fe 3+ –citric acid complexing solution in an acidic D-(+)-glucono-1,5-lactone environment. Metal coordinate interactions were formed between the released Fe 3+ ions and carboxyl groups on the salecan polysaccharide, inducing homogeneous gelation. Benefiting from this dynamic and reversible crosslinking, the salecan hydrogel exhibited self-healing and injectable behavior, facilitating the formation of the desired shapes in situ. The exposure of Fe 3+ –citric acid to UV light (365 nm) resulted in the reduction of Fe 3+ to Fe 2+ through photochemical reactions, enabling phototriggered detachment. Moreover, the hydrogel exhibited excellent biocompatibility and satisfactory antibacterial efficacy against Escherichia coli and Staphylococcus aureus of 72.5 % and 85.3 %, respectively. The adhesive strength of the salecan hydrogel to porcine skin was 1.06 ± 0.12 kPa. In vivo wound healing experiments further highlighted the advantages of the prepared hydrogel in alleviating the degree of wound inflammation and promoting tissue regeneration within 12 days.
研究领域:
材料科学
·
生物材料
·
伤口愈合
·
药学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）