JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2024
·
IF 9.4
Yimin Gong,Hui Zhang,Mingzhu Lu,Jiayu Sun,Yu Jia,Yannan Yang,Xiaofeng Liu,Bo Yin,Yaming Zhou,Yun Ling
Studies on the function-integrated nanocomposites with well-tuned morphologies have received considerable interest. Here, we reported the preparation of mesoporous carbon nanobowl integrated with stoichiometric γ-Fe 2 O 3 and GdPO 4 nanoparticles (Fe-Gd/MCN-B) for morphological advantage exploration. Followed by (i) emulsion-induced interface anisotropic assembly of polydopamine, (ii) solvent evaporation-induced sorption of Wells-Dawson-like heterometallic cluster of {Fe 6 Gd 6 P 6 } and (iii) temperature-programmed carbonization, Fe-Gd/MCN-B with the size around 200 nm was isolated. Our in-vitro studies revealed that Fe-Gd/MCN-B showed a 63.0 % amplified photoacoustic (PA) signal intensity as compared with its nanospherical analogue of Fe-Gd/MCN-S owing to the enhanced light harvesting and photothermal conversion on the interface of its nanobowl morphology. Furthermore, the combined magnetic resonance (MR) imagining, drug delivery and photothermal treatment efficacy in Fe-Gd/MCN-B were also validated in-vitro. These results demonstrated that the delicate design of the morphology of function-integrated nanocomposites is an available way for enhanced imaging performance.
研究领域:
生物医学工程
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材料科学
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医学影像学
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产品关联
DOI
PubMed
高影响因子
CERAMICS INTERNATIONAL
·
2024
·
IF 5.1
Zhiyuan Pan,Sihan Feng,Fan Li,Xuejiao Wang,Qi Zhu,Ji-Guang Li
Near-infrared phosphor converted light-emitting diodes (NIR pc-LEDs), as a state-of-the-art type of NIR sources, are finding multifaceted applications, where phosphor is a crucial component. In hope to provide new choices for NIR lighting, we synthesized in this work the two series of Ruddlesden -Popper type layered perovskite phosphors of SrLa 2 Al 2- x O 7 : x Cr 3+ ( x = 0–0.02) and SrLa 2- y Gd y Al 1.984 O 7 :0.016Cr 3+ ( y = 0–2), followed by detailed structure and luminescence investigation. SrLa 2 Al 2- x O 7 : x Cr 3+ was found to emit ∼700–800 nm NIR light under UV excitation and be able to maintain ∼54.3 % of its room temperature intensity at 423 K, which is remarkably higher than those (∼25–30 %@423 K) of the Mn 4+ activated perovskite NIR phosphors. Luminescence regulation was achieved by substituting La 3+ with Gd 3+ , and it was revealed that Gd 3+ may act as a sensitizer to significantly enhance Cr 3+ luminescence (∼346 % at 77 K) through Gd 3+ → Cr 3+ energy transfer, which was confirmed by spectral and fluorescence lifetime analysis. The observed spectral features and the influence of Gd 3+ were rationalized by considering crystal structure, local coordination, and crystal field. Finally, an NIR pc-LED device showing strong ∼700–900 nm luminescence was fabricated to show potential application of the phosphor in night vision and plant lighting.
研究领域:
材料科学
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光学工程
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产品关联
DOI
高影响因子
DALTON TRANSACTIONS
·
2018
·Vol. 47
·期 32
·11253-11263
·
IF 4.099
Yana Liu,Cheng Zhang,Chen Xu,Caixue Lin,Keke Sun,Jie Wang,Xueli Chen,Ling Li,Andrew K. Whittaker,Hai-Bing Xu
Using a facile one-step hydrothermal method, a series of metal–organic frameworks containing Gd/Tm (Gd/Tm-MOFs) were prepared successfully. Through the mutual activation of Gd3+ and Tm3+, Gd/Tm-MOFs showed unexpected excellent up-conversion luminescence (UCL) and a superior positive magnetic resonance image (MRI). Using doxorubicin hydrochloride (DOX) as a drug model, the feasibility of Gd/Tm-MOFs as a multifunctional drug carrier was demonstrated. Through modifying Gd/Tm-MOFs with uniform mesoporous silica (mSiO2) shells and folic acid (FA), the drug loading was improved up to 41.5 mg g−1, and pH responsive drug release increased to 64% from 12% by regulating the pH from 5.8 to 7.4. Also, the particles were tracked by MRI, and the second highest longitudinal relaxivity (r1) among the reported gadolinium complexes of 225.86 mM−1 s−1 was achieved. The cell imaging shows obvious blue and red luminescence under 980 nm laser excitation, and the up-conversion luminescence is unique because there is no autofluorescence from cells under 980 nm excitation. This indicates their promising application in the biological field. All the experiments indicate the promising application of Gd/Tm-MOFs in diagnosis and treatment.
研究领域:
材料科学
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生物医学工程
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药剂学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
PROCESS SAFETY AND ENVIRONMENTAL PROTECTION
·
2022
·
IF 7.926
Hussein Abdelraouf,Jing Ding,Jiayi Ren,Guanshu Zhao,Fanyang Zhou,Shuyan Guan,Xuedong Zhai,Qingliang Zhao
A novel and short-term preparation method was conducted to fabricate pristine BiVO 4, and Gadolinium (Gd) doped BiVO 4 photocatalysts at sub-100 °C. The optical, structural, morphology, microstructure, and compositional characteristics of the fabricated photocatalysts were examined, which illustrated that the doping of Gd stabilized the existence of the tetragonal phase structure and enlarged the specific surface area of the pristine BiVO 4 . The comparison of the photocatalytic performance, preparation power consumption , and preparation cost showed the superiority of Gd doped BiVO 4 photocatalyst fabricated by the Short-Term Synthesis Method at sub-100 °C. The ofloxacin (OFL) removal rate with 5%, 7%, and 10% Gd-BiVO 4 photocatalysts was 1.53, 1.61, and 1.83 times that with pristine BiVO 4 under sunlight, respectively. The degradation performance of target contaminants, including diclofenac, tetracycline HCl , ofloxacin, rhodamine B, and sulfadiazine, was demonstrated after one hour of sunlight irradiation with 5% Gd-BiVO 4 , achieving the removal efficiencies of 98.63%, 98.07%, 97.98%, 92.09%, and 78.56%, respectively. The effect of various factors on the removal performance was revealed, indicating that SO 4 2− and H 2 PO 4 − had a remarkable inhibitory effect on the degradation. The 5% Gd-BiVO 4 also showed excellent reusability and stability after five-cycle runs. The photogenerated holes (h + ) and the superoxide radicals ( • O 2 − ) were the predominant generated active species , and the possible photocatalytic mechanism for the degradation of organic contaminants was proposed. Simple prepared Gd-BiVO 4 photocatalysts were revealed to be a practical and potential choice for efficiently degrading contaminants with sunlight as green energy.
研究领域:
环境科学
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材料科学
✓ 已验证
产品关联
DOI
高影响因子
NEW JOURNAL OF CHEMISTRY
·
2025
·
IF 2.5
Xuan Liu,Jie Chao,Feifei Guo,Liangliang Chang,Zengzhe Xi
To address rapid carrier recombination and low magnetic separation efficiency in piezocatalysis, Gd/Ni co-doped BiFeO3 nanoparticles were synthesized via a sol–gel method. Rietveld refinement confirmed lattice distortion and secondary phase formation at high doping levels. Gd/Ni doping induces a phase transition in BFO from rhombohedral to orthorhombic, with the Pnma proportion reaching 84.15% at x = 0.09. Gd/Ni co-doping induced 12.7% oxygen vacancy concentration, suppressing electron–hole recombination, while enhanced Dzyaloshinskii–Moriya interaction increased saturation magnetization by 17.85-fold (magnetic recovery > 95%). The optimized sample (x = 0.09) achieved 80.94% ofloxacin degradation in 120 min (twice that of pristine BiFeO3), retaining 71.53% efficiency after 4 cycles. Radical trapping and EPR identified ˙OH and ˙O2− as dominant species, revealing a ferroelectric–piezoelectric synergistic mechanism. This work provides a strategy for designing magnetically recoverable piezocatalysts for complex wastewater treatment.
研究领域:
环境催化
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功能材料学
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纳米材料
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环境化学
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水处理技术
✓ 已验证
产品关联
DOI
高影响因子
Analytical Methods
·
2015
·Vol. 8
·期 1
·214-221
·
IF 1.821
Ai Gao,Dan Zhang,Xue-Bo Yin
To obtain comprehensive information and to compensate the limits of individual modalities in molecular imaging, the research on dual-modal imaging probes (DMIPs) attracts much interest. Here, we report a reliable and facile procedure to prepare near infrared fluorescence (NIRF)-magnetic resonance (MR) DMIPs using Cy5-labeled, Gd–Al co-doped mesoporous silica nanoparticles (MSNs). Amine-modified, Gd–Al co-doped MSNs were first synthesized through one-step co-condensation. A Cy5-NHS ester was then coupled to the amino groups to produce the DMIPs, which were denoted as Gd–Al@MSNs-Cy5. High intensity NIRF and a relaxation rate (17.7 mM−1 s−1) were observed. Featuring the lower background and the deeper penetration depth, the cutting-edge NIRF imaging was achieved. Moreover, the larger surface area of MSNs could be modified with more NIRF probes, Cy5, for improved NIRF. Following the Solomon–Bloembergen–Morgan theory, enhanced MR performance was illustrated by the relaxation rate because MSNs have a porous structure that enables access of water into the interior, and co-doping with Al in the MSNs promotes the doped amount of Gd. The exchange rate of water is much more accelerated through doping Gd and Al since a disordered pore arrangement is found in Gd–Al co-doped MSNs. The DMIPs in saline were injected into mice through the tail vein for imaging and basic pharmacokinetics studies. They were excreted by the stomach and intestine in 3 h, a circulation time long enough for imaging. Thus, Gd–Al@MSNs-Cy5 are attractive for clinical NIRF-MR dual-modal imaging by integrating the biocompatibility of MSNs, the NIRF of Cy5, and the high MR response of Gd.
研究领域:
生物医学工程
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分子影像学
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纳米医学
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产品关联
DOI
高影响因子
RSC Advances
·
2019
·Vol. 9
·期 53
·31177-31185
·
IF 3.049
Shuaiqiang Jia,Jinlong Li,Guozhe Sui,Lijuan Du,Yulin Zhang,Yan Zhuang,Boxin Li
In this study, novel Gd/TiO2@rGO (GTR) nanocomposites with high photocatalytic performance were fabricated via a one-pot solvothermal approach. During the preparation step, graphene oxide (GO) was reduced to reduced graphene oxide (rGO), and subsequently, on the surfaces of which anatase TiO2 doped with Gd metal was grown in situ with a 3D petal-like structure. Gd doping into the classical TiO2@rGO system efficiently expands the absorption range of light, improves the separation of photogenerated electrons, and increases the photocatalytic reaction sites. The specific surface areas, morphological structures, and valence and conduction bands of the obtained GTR nanocomposites were analyzed and correlated with their enhanced photocatalytic performances for the degradation of an aqueous RhB solution. The experimental results indicated that the best performance was achieved with the 3% GTR composite, which exhibited the highest photoelectrocatalytic activity because of two aspects: the rapid separation of electrons and holes, and improvement in adsorption capacity. As compared with pure TiO2, the GTR composites demonstrated enhanced photoactivity due to synergetic effects between the effective photo-induced electron transfer from TiO2 to the surface of the rGO acceptor through interfacial interactions and the variation of structure and electrons under the adoption of Gd.
研究领域:
材料科学
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环境科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
MAGNETIC RESONANCE IMAGING
·
2017
·
IF 2.225
Chuanling Wan,Youyang Zhan,Rong Xue,Yijie Wu,Xiaojing Li,Fengkui Pei
Objectives The purposes of this study were (1) to detect the dynamic metabonomic changes induced by gadopentetate dimeglumine (Gd-DTPA) and (2) to investigate the potential metabolic disturbances associated with the pathogenesis of nephrogenic systemic fibrosis (NSF) at the early stage. Methods A nuclear magnetic resonance (NMR)-based metabolomics approach was used to investigate the urinary and serum metabolic changes induced by a single tail vein injection of Gd-DTPA (dosed at 2 and 5 mmol/kg body weight) in rats. Urine and serum samples were collected on days 1, 2 and 7 after dosing. Results Metabolic responses of rats to Gd-DTPA administration were systematic involving changes in lipid metabolism , glucose metabolism , TCA cycle, amino acid metabolism and gut microbiota functions. Urinary and serum metabonomic recovery could be observed in both the 2 and 5 mmol/kg body weight group, but the metabolic effects of high-dosed (5 mmol/kg body weight) Gd-DTPA lasted longer. It is worth noting that hyperlipidemia was observed after Gd-DTPA injection, and nicotinate might play a role in the subsequent self-recovery of lipid metabolism. The disturbance of tyrosine , glutamate and gut microbiota metabolism might associate with the progression of NSF. Conclusion These findings offered essential information about the metabolic changes induced by Gd-DTPA, and could be potentially important for investigating the pathogenesis of NSF at the early stage. Moreover, the recovery of rats administrated with Gd-DTPA may have implications in the treatment of early stage NSF.
研究领域:
代谢组学
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药理学
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毒理学
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肾病学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ACS Biomaterials Science & Engineering
·
2016
·
IF 0
Dan Yang,Guixin Yang,Shili Gai,Fei He,Ruichan Lv,Yunlu Dai,Piaoping Yang
Exploring a combined anticancer therapeutic strategy to overcome the limitations of a single mode and pursue higher therapeutic efficiency is highly promising in both fundamental and clinical investigations. Herein, a theranostic nanoplatform based on mesoporous silica, which is functionalized by hybrid nanosphere photosensitizer Chlorin e6 (Ce6), photothermal agent carbon dots (CDs), and imaging agent Gd (III) ions has been rationally designed and fabricated. A thermo/pH-coupling sensitive polymer (P(NIPAm-co-MAA)) coated on a composite acted as a key “gatekeeper” to control drug release at the appropriate time and location. Upon light irradiation, two-mode synergistic therapeutic effect of photodynamic and photothermal therapy can be achieved by photoactive Ce6 and CDs. Meanwhile, the CDs loaded in the channels of mesoporous silica hybrid spheres can also play a role in handling the “gatekeeper” polymer to control the drug release process. Combined with the thermo/pH-sensitive drug release-induced controllable chemotherapy, this platform shows synergistic therapeutic efficacy better than any single/dual therapy, which is confirmed with evidence from in vivo and in vitro assays. Considering the chelated Gd3+ simultaneously introduced magnetic resonance imaging (MRI) and computed tomography (CT) properties, this multifunctional platform should have excellent potential in the imaging-guided cancer therapy field.
研究领域:
肿瘤学
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纳米医学
·
影像学
✓ 已验证
产品关联
DOI
PubMed
JOURNAL OF ALLOYS AND COMPOUNDS
·
2023
·
IF 6.2
Huan Chai,Huilin Niu,Lili Gao,Jun Jin
The onset potential is an important descriptor of the photoelectrochemical water oxidation performance of photoanodes. Herein, we prepared Gd-doped hematite (Gd-Fe 2 O 3 )/iron (III) oxyhydroxide (FeOOH) core-shell photoanodes by in-situ isovalent doping and secondary hydrothermal treatment . This Gd-Fe 2 O 3 /FeOOH photoanode shows a record alkaline water oxidation onset potential (0.59 V vs. reversible hydrogen electrode) in hematite-based photoanodes and a 2.4-fold increase in photocurrent density over pristine hematite . Detailed studies demonstrate that the origin of the ultra-low onset potential is mainly attributed to the synergistic effect of isovalent Gd-doping and FeOOH cocatalyst. Specifically, Gd doping enhances donor density and reduces charge transport resistance, and FeOOH cocatalyst significantly improves water oxidation kinetics. In addition, the strong interfacial coupling of FeOOH and Gd-Fe 2 O 3 promotes electron flow, which also improves the charge separation remarkably. This work gives hope for the achievement of stable and bias-free hematite-based photoanodes.
研究领域:
材料科学
·
能源科学
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产品关联
DOI
高影响因子
NEW JOURNAL OF CHEMISTRY
·
2022
·Vol. 46
·期 10
·4806-4813
·
IF 3.925
Jie Song,Leilei Sun,Hongchao Geng,Wenlong Tan,Deshuai Zhen,Qingyun Cai
β-Phase NaYF4:Yb,Tm,Gd up-conversion nanorods (UCNRs) with high uniformity were synthesized by a solvothermal method. The optimal fluorescence intensity of UCNRs was explored. After further modification with Materials of Institute Lavoisier-100(Fe) (MIL-100(Fe)) by the layer-by-layer self-assembly method, near-infrared light-triggered UCNR@MIL-100(Fe) nanomaterials with excellent antibacterial performances were constructed. A core–shell structure was constructed and confirmed by transmission electron microscopy (TEM). Reactive oxidizing species (ROS) detection indicated that the nanomaterials owned good photodynamic efficacy. The antibacterial experiments showed that the nanomaterials with 980 nm light irradiation and hydrogen peroxide (H2O2) had good antibacterial activity against Gram-negative and Gram-positive bacteria. Under 980 nm laser excitation, UCNRs generated ultraviolet and visible light to activate MIL-100(Fe) and induced a photo-Fenton reaction, which further produced oxygen species for antibacterial applications.
研究领域:
纳米技术
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材料科学
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生物医学工程
·
化学
·
微生物学
✓ 已验证
产品关联
DOI
高影响因子
Nanoscale
·
2023
·Vol. 15
·期 9
·4457-4468
·
IF 6.7
Chao Cai,Feng Tian,Junping Ma,Zipei Yu,Mo Yang,Changqing Yi
Precision medicine urges the development of theranostics which can efficiently integrate precise diagnosis and effective therapy. In this study, a facile synthesis of Ir/Gd bimetallic oxide nanotheranostics (termed BSA@Gd2O3/IrO2 NPs) with good biocompatibility was demonstrated using a biomineralization method where bovine serum albumin (BSA) served as a versatile template. BSA@Gd2O3/IrO2 NPs exhibited high longitudinal relaxivity (5.2 mM−1 s−1) and X-ray absorption capability (14.5 Hu mM−1), illustrating them to be a good contrast agent for magnetic resonance (MR) and computed tomography (CT) dual-modal imaging. Moreover, BSA@Gd2O3/IrO2 NPs can act as not only a photothermal conversion agent with ultrahigh efficiency (66.7%) as well as a good photosensitizer, but also an effective catalase to decompose endogenous H2O2 to produce O2, thus relieving hypoxia and enhancing the phototherapeutic effect. Both in vitro and in vivo experiments demonstrated the high effectiveness of BSA@Gd2O3/IrO2 NPs in MR/CT dual-modal imaging and photothermal and photodynamic synergistic tumor treatments. This work sheds new light on the development of versatile nanotheranostic systems using mild and robust biomineralization methods.
研究领域:
生物医学工程
·
纳米医学
·
肿瘤学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）