APPLIED SURFACE SCIENCE
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2022
·
IF 7.392
Binshu Sun,Jianhong Zheng,Dewu Yin,Huile Jin,Xin Wang,Quanlong Xu,Aili Liu,Shun Wang
Cocatalyst can greatly facilitate the charge separation efficiency and decrease the activation barrier of a specific reaction, thus contributing the improved photocatalytic performance. Herein, PdS/CdS/MoS 2 was synthesized via a facile microwave-assisted approach. Owing to the coexistence of PdS and MoS 2 , respectively serving as oxidation and reduction cocatalyst, PdS/CdS/MoS 2 displayed enhanced photocatalytic performance in both hydrogen production (6610 μmol·g −1 ·h −1 ) and benzylamine oxidation (87% conversion) in comparison with the individual and binary composite counterparts. The improved photocatalytic activity was mainly attributed to the high charge separation efficiency and lowed activation barrier. Furthermore, the introduction of PdS can timely extract photogenerated holes from CdS, which effectively inhibits the photo-corrosion of CdS, endowing it with high stability. This work paves the way for developing efficient chalcogenide photocatalysts.
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Journal of Materials Chemistry B
·
2022
·Vol. 10
·期 18
·3541-3549
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IF 7.571
Xin Zhang,Cheng Wang,Jiangjie Wu,Ben Zheng,Si Chen,Meng Ma,Yanqin Shi,Huiwen He,Xu Wang
Although more than 2.2 million cranial repair surgical operations are performed every year, orthopedic doctors still dream of excellent artificial repair materials with suitable strength, on-site and on-demand fast-shaping properties, and bone induction properties. However, fast-shaping and high-strength properties seem to contradict each other, and even mineralized hydrogels, which already have excellent strength and bone induction properties, are not ideal candidates, since they lack the plasticity needed for complex craniofacial surface use during the essential mechanism of the process of the cleavage of inorganic ions, nucleation, and growth. Here, we report a novel mineralized hydrogel based on dispersing mineral ions prior to use and then inducing inorganic formation by decreasing the temperature, which endows the hydrogels with the characteristics of precise customization at an appropriate degree of mineralization and simultaneously achieves suitable mechanical properties and sufficient calcium supply for bone regeneration. Additionally, the calcium ion content in the water of the matrix will change with the temperature, and, thus, the conductivity of the mineralized hydrogels will change accordingly. This implements the ability to warn of inflammation in a timely fashion in the form of a temperature sensor. Therefore, this temperature-responsive hydrogel effectively achieves the aim of versatile material design.
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Fermentation-Basel
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2022
·Vol. 8
·期 1
·25
·
IF 5.123
Wen-Tao Sun,Yuan Huang,Chang-Rong Wu,Chao Peng,Yu-Long Zheng,Chao Chen,Jun Hao
In this study, the influence of two lactic acid bacteria (LAB) strains [Lactobacillus rhamnosusBDy (LR-BDy) andLactobacillus buchneriTSy (LB-TSy)] selected from Southwest China on the fermentation characteristics and in vitro gas production ofBroussonetia papyrifera(paper mulberry) silage were experimentally explored. The experimental groups were a control group (C), an LB-TSy treatment (LB), an LR-BDy treatment (LR), and an LR-BDy + LB-TSy hybrid group (LR × LB). After the LAB were added, the pH value of paper mulberry silage significantly declined (p< 0.05), and the crude protein content was effectively preserved (p< 0.05). However, no significant changes were found in the levels of neutral detergent fiber, acid detergent fiber, and crude ash (p> 0.05). The lactic acid content in paper mulberry silage was evidently increased (p< 0.05). The in vitro gas production in the LR at 36, 48, and 72 h were markedly higher than that in the other treatments (p< 0.05). Owing to the addition of LAB, the microbial diversity in paper mulberry silage was reduced, while the relative bacterial abundance ofLactobacilluswas enhanced. Hence, the addition of LAB selected from the warm and humid region in Southwest China can improve the quality of paper mulberry silage and elevate its feeding value in this region.Keywords:paper mulberry;silage;in vitro gas production;microbial community;lactic acid bacteria
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ELECTROANALYSIS
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2022
·Vol. 34
·期 9
·1411-1421
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IF 3.077
Xiaotao Zhang,Yi Wei,Huihuang Wu,Hongli Yan,Yiming Liu,Željka Lučev Vasić,Haibo Pan,Mario Cifrek,Min Du,Yueming Gao
On-site quantitative detection provides the opportunity for accurate and timely health care, clinical diagnosis, environmental monitoring, and food analysis. A variety of portable electrochemical detection instruments have been developed at present for on-site quantitative detection use, including commercially available portable potentiostats, but the reality is that these electrochemical detection devices still have the problem of narrow output voltage range and detection current range, and their performance of output voltage resolution and detection current resolution is still unsatisfactory. The narrow voltage or current range makes it difficult for some chemical reactions with peaks outside the range to proceed, and the insufficiency of voltage resolution and detection current resolution are key parameters restricting the detection accuracy of existing devices. In this regard, it is urgent to carry out partial transformation of the existing device to increase the use range and detection accuracy of the device. In the current work, a smartphone-based electrochemical on-site quantitative detection device was developed. The device comprises a portable small potentiostat, a smartphone equipped with a specially designed Android electrochemical detection application, and a disposable sensor (NiONP modified screen-printed electrode [SPE]). The potentiostat can realize electrochemical detection methods, including cyclic voltammetry, chronoamperometry, and differential pulse voltammetry. In addition, the potentiostat can output a potential range −2.047∼+2.047 V with a current detection sensitivity scale 1×10 −8 ∼1×10 −3 A, and the current detection range could reach ±10 nA∼±10 mA. Most importantly, the current detection resolution of the potentiostat can reach 0.003 % (3.125 pA on ±10 nA range). The smartphone was used for communicating with the potentiostat, setting detection parameters, and mapping voltammograms in real time. The SPE was modified with nickel oxide nanoparticles and perfluorinated resin solution, which were employed as sensors to convert and amplify the electrochemical current response during the on-site quantitative detection. Results indicated that the device features excellent performance for the lactate detection. The device covered a linear range 0.1∼30 mM on lactate detection with the correlation coefficient (R 2 ) reaching 0.997.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2022
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IF 8.025
Dandan Cui,Jin Yang,Bosi Lu,Lansheng Deng,Hong Shen
Mantis shrimp waste (Oratosquilla oratoria) is a good source of chitin. The applicability of microwave-assisted organic acids and proteases for extracting chitin from mantis shrimp shell waste was evaluated, and the extracted-chitin was characterized by scanning electron microscopy (SEM), Fourier-transform infrared spectroscopy (FTIR), X-ray diffraction (XRD) and thermogravimetric analysis (TGA). Moreover, the effects of nanochitin on the growth of pak choi ( Brassica campestris L.ssp.) were also investigated. The results indicated that alkaline protease (4000 U/g, microwave heating at 60 °C, 10 min) and malic acid (5%, 320 W, 5 min) exhibited excellent potential for deproteinizing and demineralizing shells. The deproteinization and demineralization yields were 92.78% and 94.11%, respectively, and the chitin yield was 15.6%. The extracted-chitin had a highly porous structure and exhibited excellent crystallinity and thermostability compared with chitin prepared by traditional chemical methods. Furthermore, 0.003% nanochitin significantly enhanced photosynthesis, which improved the pak choi fresh weight by 22.94%, and improved the accumulation of isothiocyanates in its leaves. This study provides an alternative approach for the high-value utilization of mantis shrimp waste, and reveals the potential of chitin for application in agricultural production.
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Nano Energy
·
2021
·
IF 17.881
Shengying Cai,Changshun Xu,Danfeng Jiang,Meiling Yuan,Qingwen Zhang,Zhaoling Li,Yi Wang
Developing wearable and noninvasive electrochemical devices for glucose monitoring is desirable for diabetes diagnostics and management. However, the adoptions are restricted by their poor reliability due to diluted glucose densities in commonly-used body fluids while lack of highly sensitive electrodes. Graphene fiber fabric, which is macroscopically paper-like and assembled by wet-fused graphene fibers, provides excellent electrical and mechanical properties as well as penetration paths for liquids, showing great potentials for electrochemical monitoring . Additionally, the graphene fiber fabric as a sensing patch provides excellent air-permeability which is necessary for wearing comfort but has rarely been addressed. As a result, the Prussian blue-decorated graphene fiber fabric exhibits a high electrochemical sensitivity to hydrogen peroxide (7298.7 μA mM −1 cm −2 ). After being modified by glucose oxidase and chitosan, it delivers both high selectivity and electrochemical sensitivity to glucose (1539.53 μA mM −1 cm −2 in the concentration range of 2–220 μM, and 948.48 μA mM −1 cm −2 in the concentration range of 220–650 μM). We ascribe these performances to high-speed transfer paths for electrons and electrolytes in resultant electrodes. Additionally, the spontaneous absorption of body liquids by graphene fiber fabric after deposition of hydrophilic Prussian blue improves the utilization of active materials. Finally, the graphene fiber fabric used as a dry sensing patch was applied on human skin for the in vivo noninvasive glucose monitoring with the reverse iontophoresis (RI) technology, which showed good correlation to glucose levels measured by a commercial finger-prick glucometer.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2023
·
IF 8.2
Jian Hu,Bo Liu,Tao Sun,Jiatao Zhang,Xueyan Yun,Tungalag Dong
The irreconcilable paradox between barrier performance and ductility is a “stumbling block” restricting the development of poly(L-lactic acid) (PLLA) films in the packaging industry. In this work, we reported the fabrication of an ultra-thin PLLA-based film with barrier properties and ductility by adjusting the polarity and conformational behavior of the polymer chains. Firstly, a novel unsaturated poly(L-lactic acid- co -butyrate itaconate) P(LA-BI) copolymer containing C C double bonds was synthesized using melt polycondensation. The results reveal that the addition of 60 % of P(LA-BI) enables PLLA film to achieve an elongation at a break of 83.6 % due to P(LA-BI) containing partially branched structures, which resulted in the polymer chains being arranged more in a high-energy gg conformer. Meanwhile, because of the large number of C O polar groups in P(LA-BI), PLLA/P(LA-BI) 60 film show CO 2 and O 2 permeability coefficients (CDP and OP) of 1.8 and 0.45 × 10 −8 g·m·m −2 ·h −1 ·Pa −1 respectively, which means that it has excellent gas barrier properties. Moreover, PLLA/P(LA-BI) 60 film shows a 33.3 % increase in CO 2 /O 2 ratio and an excellent ultraviolet (UV) barrier performance compared to neat PLLA. Preservation results suggested that the CO 2 and O 2 levels within the package could be regulated by varying the amount of P(LA-BI) added. Among them, PLLA/P(LA-BI) 40 film generated a more desirable CO 2 and O 2 atmosphere for cherry tomatoes preservation, which was reflected by the delaying of senescence, discoloration, and decay, inhibition of oxidative cell damage through reduced malondialdehyde production, and maintenance of nutritional and flavor substances in cherry tomatoes. This PLLA-based film offers the advantages of operational simplicity, environmental friendliness, and inexpensive cost, making it great promising for food preservation and other applications requiring barrier properties and ductility.
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高影响因子
Frontiers in Endocrinology
·
2023
·
IF 5.2
Chengxin Li,Lewei Zheng,Gaoran Xu,Qianqian Yuan,Ziyang Di,Yalong Yang,Xingxing Dong,Jinxuan Hou,Gaosong Wu
Background Breast cancer (BRCA) has become the most diagnosed cancer worldwide for female and seriously endanger female health. The epithelial-mesenchymal transition (EMT) process is associated with metastasis and drug resistance in BRCA patients. However, the prognostic value of EMT-related lncRNA in BRCA still needs to be revealed. The aim of this study is to construct an EMT-related lncRNA (ERL) signature with accuracy predictive ability for the prognosis of BRCA patients. Methods RNA-seq expression data and Clinical characteristics obtained from the TCGA (The Cancer Genome Atlas) were used in the study. First, we identified the EMT-related lncRNA by the Pearson correlation analysis. An EMT-related lncRNAs prognostic risk signature was constructed using univariate Cox regression and Lasso-penalized Cox regression analyses. The model’s performance was validated using Kaplan-Meier (KM) survival analysis, ROC curve and C-index. Finally, a nomogram was constructed for clinical practice in evaluating the patients with BRCA and validated by calibration curve and decision curve analysis (DCA). We also evaluated the drug sensitivity of signature lncRNA and the tumor immune cell infiltration in breast cancer. Results We constructed a 10-lncRNA risk score signature based on the lncRNAs associated with the EMT process. We could assign BRCA patients to the high- and low-risk group according to the median risk score. The prognostic risk signature showed excellent accuracy and demonstrated sufficient independence from other clinical characteristics. The immune cell infiltration analysis showed that the prognostic risk signature was related to the infiltration of the immune cell subtype. Drug sensitivity analysis proved ERLs signature could effectively predict the sensitivity of patients to common chemotherapy drugs in BRCA and provide guidance for chemotherapy drugs for high-risk and low-risk patients. Conclusion Our ERL signature and nomogram have excellent prognostic value and could become reliable tools for clinical guidance.
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高影响因子
Journal of Functional Foods
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2023
·
IF 5.6
Jichun Zhao,Zhengwei Tan,Ruyu Zhang,Weizhou Li,Fuhua Li,Jian Ming
This study investigated the alterations in the phytochemical components and the antioxidant abilities of brine- and NaCl-fermented carrots and their effects on the lipid metabolism and microbial community in high-fat diet (HFD)-fed mice. Results showed that brine-fermentation significantly improved the contents of total dietary fiber, total phenols and β-carotene by 57 %, 48 % and 117 %, respectively. Fermented carrots possessed a higher level of antioxidant activities ( P < 0.05). Furthermore, fermented carrot attenuated the increase in body weight, alleviated liver injury and oxidative stress but also promoted the lipid metabolism and reduced fatty acid accumulation in vivo , which were correlated with the total phenols and dietary fiber contents. Further investigation demonstrated that fermented carrots can attenuate HFD-induced lipid accumulation through the AMPK pathway and restoring the gut microbiota in HFD mice. Overall, fermented carrots can modulate the lipid accumulation in the HFD mice through the AMPK pathway and the microbiota community.
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JOURNAL OF POLYMER RESEARCH
·
2023
·Vol. 30
·期 6
·1-13
·
IF 2.8
Zou Yulong,He Qiaobai,Wang Shanrong,Zou Fang,Lu Xili,Sun Zhijie,Li Li
Poly(L-lactide-co-ε-caprolactone) (PLCL) nanocomposites reinforced with graphene oxide modified by poly (L-lactic acid) (g-GO) were prepared by solution casting, where the graft ratio of PLLA to GO is about 11.7%. The results show that the g-GO possesses improved dispersion and interface interactions with the PLCL matrix, therefore, the final mechanical properties of nanocomposites are enhanced. Comparing with neat PLCL, the tensile strength and elongation at break of (1wt%)g-GO/PLCL are increased by 86.4% and 82.4%, respectively. Moreover, the g-GO/PLCL nanocomposite containing 1 wt% g-GO exhibits excellent thermal- induced and NIR light-induced shape memory effects and the shape recovery ratio is all up to 95%. The nanocomposites also have favorable antibacterial properties. The g-GO/PLCL nanocomposites with good NIR light-induced shape memory effect, antibacterial properties, biodegradability and biocompatibility have great potential for minimally invasive surgery.
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Cell Death & Disease
·
2026
·
IF 12.2
Liu Yanzhu,Yang Rui,Li Dongmei,Zeng Weiquan,Wei Yan,Huang Zhihui,Wang Ying
Tumor hypoxia/necrosis as a hallmark of glioblastoma (GBM) is strongly associated with malignant progression and poor prognosis of GBM, however, its roles and mechanisms in the behaviors of neighboring surviving GBM cells remain poorly understood. Here, we analyzed public transcriptomic datasets to characterize gene expression in hypoxic/necrotic regions in GBM, and found that the glycolytic pathway was activated in tumor cells from these regions. Furthermore, glycolysis was also elevated in GBM cells under hypoxia/necrosis-mimicking conditions in vitro. Notably, hypoxia/necrosis-mimicking cells-derived lactate promoted the viability and proliferation and migration of neighboring surviving GBM cells. Mechanistically, lactate induced the lactylation of histone H3 lysine 9 (H3K9la), activating transcription of S-phase kinase-associated protein 2 (SKP2). This transcriptional activation was associated with H3K9la enrichment at the SKP2 promoter in GBM cells. SKP2 knockdown inhibited the tumor-promoting effects induced by lactate in GBM cells. Finally, in the orthotopic murine GBM model, hypoxia/necrosis-mimicking cells promoted GBM progression via SKP2 signaling. These results identify a hypoxia/necrosis-driven metabolic-epigenetic axis in GBM, in which lactate-mediated H3K9la promotes GBM progression through SKP2 signaling, revealing SKP2 as a potential therapeutic target for disrupting hypoxia/necrosis-associated malignancy of GBM.
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ACS Sustainable Chemistry & Engineering
·
2023
·
IF 8.4
Renjie Yang,Pengfei Chen,Heng Zhong,Fangming Jin
Lactic acid (LA) serves as a crucial platform chemical and monomer for the production of biodegradable plastic known as polylactic acid. Presently, LA is predominantly derived from the fermentation of crop syrups, a process that consumes substantial grain reserves and poses a significant threat to food security. Food waste (FW) represents a promising alternative source for LA production due to its abundant carbohydrate content. This study proposes an efficient and expeditious method for converting FW into LA at a relatively low temperature of 70 °C. The method involves the utilization of hydrochloric acid (HCl) recovered from poly(vinyl chloride) plastic (PVC) for the acid pretreatment of FW. Remarkably, this approach achieves a high LA yield of over 60% (molar yield) from simulated FW, all without the need for complex catalysts. Furthermore, the conversion process benefits from Ba2+-assisted base catalysis, demonstrating robust performance regardless of variations in the major components present in FW. This research not only offers an effective means of valorizing FW but also presents an innovative strategy to reduce the reliance of LA production on food reserves.
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危险品化学品经营许可证（带存储）