DESALINATION
·
2019
·
IF 6.035
Nan Li,Li Yu,Zhiqun Xiao,Can Jiang,Baoyu Gao,Zhining Wang
Biofouling is an inevitable issue that can increase operating cost and reduce treatment efficiency, limiting the widespread application of thin film composite (TFC) membranes. Laponite (Lap) is a synthetic silicate nanoclay with the nanodisk structure, which can be used as a suitable metal ions carrier because it is ion exchangeable and biocompatible. In this work, Ag/Lap, Cu/Lap and Zn/Lap were synthesized by ion exchange method. Subsequently, Lap and metal ion exchanged Lap (M/Lap) were incorporated in polyamide (PA) layers to develop thin film nanocomposite (TFN) membranes by interfacial polymerization . The developed TFN membranes possessed improved water flux and remained a good NaCl rejection rate. Meanwhile, the incorporation of M/Lap endowed the TFN membrane with improved fouling resistance . The TFN-M/Lap membranes showed effective bactericidal properties against both E. coli and S. aureus , particularly the TFN-Ag/Lap membrane with prominent antibacterial properties against E. coli (99.2%) and S. aureus (95.1%). Fluorescence experiment, reactive oxygen species detection and the release of metal ions were also examined. The excellent antibiofouling properties of TFN-M/Lap membranes could be interpreted by cell damage resulting from contact between bacterial and metal ions. Our work provides the potential antibacterial materials and a facile approach to develop novel antibiofouling TFN membranes.
研究领域:
环境工程
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材料科学
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化学工程
·
膜技术
✓ 已验证
产品关联
DOI
高影响因子
Materials Science & Engineering C-Materials for Biological Applications
·
2019
·
IF 4.959
Ling Zheng,Bingjie Zhou,Xiaofeng Qiu,Xin Xu,Gang Li,Wayne Y.W. Lee,Jia Jiang,Yulin Li
The multidrug resistance of tumor cells has been creating a high requirement on development of nanocarriers for administration of different drugs, among which their drug loading capacity and controllable release properties are the key factors to overcome tumor drug resistance. This study aims to use a kind of bioactive 2D nanoplatelets (25 nm in diameter and 0.92 nm in thickness) to load different anticancer drugs (doxorubicin and methotrexate) via a step-by-step assembly, where variation of each drug amount can be used for adjustment of the sizes of the resulting nanocomplexes. The dual-drug loaded nanosystems allow for a sequential release of the loaded drugs. Furthermore, drug release rate can be accelerated under both acidic pathological triggers of tumors and/or by heating treatment, resulting in a synergistic anticancer bioactivity. The drug-mediated formation of nanocarriers may enlighten a design of novel nanoplatform for co-delivery of therapeutic agents, beyond anticancer drugs, in a combinative way for drug delivery applications.
研究领域:
药剂学
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肿瘤学
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纳米医学
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产品关联
DOI
PubMed
高影响因子
EUROPEAN JOURNAL OF INORGANIC CHEMISTRY
·
2020
·Vol. 2020
·期 22
·2170-2176
·
IF 2.529
Xueshuai Chen,Rongli Jiang,Zihan Zhou,Xingwen Wang
Graphical SAPO-34 zeolite was successfully synthesized from laponite as the single Si source. Laponite itself contains Li and Mg atoms, which were subsequently introduced into the structure of SAPO-34 via depolymerization-reorganization of laponite. Metal incorporation can reduce the amount of stronger acid sites and enhance the catalytic performance in the MTO reaction. In this work, SAPO-34 zeolite with high catalytic activity was successfully synthesized by hydrothermal method from laponite as the single Si source. Compared with the traditional method of synthesizing zeolites from clay, the laponite after swelling can be directly used in the synthesis process of zeolite. The crystallization behavior of SAPO-34 synthesized from laponite was investigated by XRD, FTIR, N 2 adsorption–desorption, SEM-EDX, ICP-MS, and DR-UV/Vis. The process can be summarized as follows: the Si and Mg elements were produced by the depolymerization of laponite, then the primary building units of SAPO-34 zeolite were formed under hydrothermal conditions; finally, the crystal nucleus began to form, and crystallization was triggered. Compared with the conventional SAPO-34 synthesized from TEOS, the SAPO-34 synthesized from laponite exhibited higher selectivity to light olefins and longer lifetime, which can be attributed to the suitable strength of acidity. This work points to a straightforward route to the synthesis of SAPO-34 from laponite.
研究领域:
材料科学
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催化化学
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产品关联
DOI
高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
·
2025
·
IF 2.8
Hongyu Xu,Jingjing Zhang,Xue Lv
Due to their biocompatibility and tissue-like properties, hydrogels have garnered considerable interest in bioelectronics field. Nevertheless, their practical implementation is limited by factors such as inadequate mechanical strength, weak interface adhesion, and the lack of antimicrobial properties. To address these challenges, a novel conductive hydrogel was synthesized through free radical polymerization, incorporating laponite (LA), tannic acid (TA), polyacrylic acid (PAA), and polyacrylamide (pAAm). An innovative approach was employed to enhance LA's dispersion through ionic liquid (IL) in water through electrostatic interactions. The integration of TA, PAA, and PAAm with LA sheets via multiple hydrogen bonds resulted in excellent mechanical properties. The resulting P(AAm-AA)/IL-LA/TA hydrogel exhibits impressive characteristics, including a fracture stress of 0.44 MPa, a strain of 1800%. Notably, the hydrogel's TA component exhibits strong antibacterial activity against Staphylococcus aureus and Escherichia coli . This advanced hydrogel sensor effectively monitors human movements, displaying a gauge factor of 12.7. Furthermore, its versatile and conductive nature facilitates adhesion to a wide range of substrates, making it a promising candidate for applications in human activity monitoring, electronic devices, and medical health surveillance.
研究领域:
生物医学工程
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材料科学
✓ 已验证
产品关联
DOI
高影响因子
APPLIED CLAY SCIENCE
·
2024
·
IF 5.3
Hao Zhang,Chaopeng Fu,Jianhao Ding,Guoqiang Xu,Chunhui Zhou,Zhenyu He,Zhimin Ou,Dongshen Tong,Minyang Qiu,Xiangdong Zhou,Xiaonian Li
An electrostatic adsorption-based, surface-enhanced Raman scattering (SERS) assay for the detection of charged analytes was developed, which utilized Ag-deposited laponite nanoparticles (Ag@Lap NPs) as both a SERS substrate and negatively charged absorber for the capture of positively charged analytes, such as methylene blue (MB) and rhodamine B (RB). The strong electrostatic interaction between the MB analyte and the Ag@Lap NPs resulted in an effective concentration of MB on the Ag content of Ag@Lap and provided a limit of detection (LOD) sensitivity of 10 −11 M, which was more sensitive by a factor of 25,000 over the LOD of MB (0.25 × 10 −6 M) in a similar SERS assay using bare Ag NPs with low charges. Additionally, a 100-fold improvement in LOD was also observed for RB analyte on Ag@Lap NPs over that on bare Ag NPs. Unlike positively charged, the negatively charged analytes, such as direct black-168 (DB-168) and methyl orange (MO), exhibited a weaker adsorption on the same negatively charged surface of Ag@Lap NPs due to electrostatic repulsion, leading to a lower SERS sensitivity. These results indicated that the electrostatic attraction between the analytes and SERS substrate played an important role in enriching the number of analytes on the active substrate to significantly improve the SERS intensity, suggesting a new strategy, which could be easily adapted to environmental analysis and biosensor applications by concentrating and detecting charged analytes, such as pollutants and dye molecules in nanotags.
研究领域:
分析化学
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纳米材料科学
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环境科学
✓ 已验证
产品关联
DOI
高影响因子
POLYMER
·
2023
·
IF 4.6
Yuhui Xie,Xue Lv,Xinyi Sui,Song Tian,Li'an Jiang,Shulin Sun
In this paper, the physicochemical double cross-linking nanocomposite hydrogels were prepared. Due to the addition of ionic liquid (1-butyl-3-methylimidazolium chloride salt), Laponite cannot spontaneously form a high thixotropic gel in water. The homogeneously dispersed Laponite nanosheets act as dynamic physical crosslinking sites, which cooperate with the chemical crosslinking center of MBA in the polymer chain segments and build a super-strong and super-tough hydrogel network structure. The PAM/Laponite/IL nanocomposite hydrogel achieves excellent tensile strength up to 1191 Kpa, a high tensile strain of 6842%, and a very high toughness of 26.62 MJ/m 3 . In this paper, an effective mechanism to enhance the mechanical properties of the hydrogel is proposed based on the structural evolution of Laponite. This highly flexible nanocomposite hydrogel shows excellent potential as a load-bearing material.
研究领域:
材料科学
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高分子化学
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纳米技术
✓ 已验证
产品关联
DOI
高影响因子
Royal Society Open Science
·
2022
·Vol. 9
·期 10
·
IF 3.653
Xiaodong Dong,Jinsheng Sun,Xianbin Huang,Kaihe Lv,Zhishi Zhou,Chongyang Gao
In drilling deep complex formations, most drilling fluid additives have insufficient temperature and salt tolerance, resulting in the decline of drilling fluid performance. This study used 2-acrylamide-2-methylpropane sulfonic acid, acrylamide, dimethyl diallyl ammonium chloride and modified nano-laponite to synthesize a nanocomposite filtrate reducer (ANDP) with excellent temperature and salt resistance, which can maintain the performance of drilling fluid. The structure of ANDP was analysed by a transmission electron microscope and an infrared spectrometer. The thermal stability of ANDP was studied by thermogravimetric analysis. The performance of ANDP was evaluated in a water-based drilling fluid. The mechanism was analysed per clay particle size distribution, Zeta potential, filter cake permeability and scanning electron microscopy imaging. The results show that ANDP has good thermal stability and the expected molecular structure. The filtration of freshwater drilling fluid after ageing at 200°C is 10.4 ml and that of saturated brine drilling fluid is 6.4 ml after ageing at 150°C. Mechanism analysis suggests that the ANDP increases the thickness of clay particle hydration layer and maintains the colloidal stability of the drilling fluid. ANDP inhibits the agglomeration of clay particles and significantly reduces the filtration by forming dense mud cake.
研究领域:
石油工程
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材料科学
·
化学工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
BIOMACROMOLECULES
·
2024
·
IF 5.5
Yan Fang,Yukai Lin,Linyu Wang,Yunxiang Weng,Qinhui Chen,Haiqing Liu
Hemostatic powder is widely employed for emergency bleeding control due to its ability to conform to irregularly shaped wounds, ease of use, and stable storage. However, current powders exhibit limited tissue adhesion and insufficient support for thrombus formation, making them easily washed away by blood. In this study, a hybrid powder (QAL) was produced by mixing quaternized chitosan (QCS) powder, catechol-modified alginate (Cat-SA) powder, and laponite (Lap) powder. Upon addition of QAL, the blood quickly transformed to a robust and adhesive blood gel. The adhesion strength of the blood gel was up to 31.33 ± 1.56 kPa. When compared with Celox, QAL showed superior performance in promoting hemostasis. Additionally, QAL exhibited effectiveness in eliminating bacteria while also demonstrating outstanding biocompatibility with cells and blood. These favorable properties, including strong coagulation, adhesion to wet tissue, antibacterial activity, biosafety, ease of use, and stable storage, make QAL a promising emergency hemostatic agent.
研究领域:
生物医学工程
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材料科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ACS Applied Nano Materials
·
2024
·
IF 5.3
Ling Lin,Yuanhao Luo
Water-based drilling fluids are prone to contamination by high temperatures and high salt, resulting in a deteriorated filtration performance of the drilling fluids, posing a significant threat to the safety of drilling operations. This study utilized N,N-dimethylacrylamide (DMAA), 2-acrylamido-2-methyl-1-propanesulfonic acid (AMPS), dimethyldiallylammonium chloride (DMDAAC), N-vinylpyrrolidone (NVP), and nanomaterials (nano-SiO2 and nanolaponite) to prepare a polymer nanocomposite NP-3 as a filtratef reducer for drilling fluids. The thermal stability evaluation of the polymer solution revealed that the thermal degradation temperature order of the different structural units of the polymer is DMAA < AMPS ≈ DMDAAC < NVP, and the temperature resistance of NP-3 in the solution is 220 °C. Evaluation of drilling fluid performance demonstrated that 3.5 wt % NP-3 enabled the drilling fluid to resist contamination from 15 wt % NaCl at 230 °C, with an American Petroleum Institute (API) filtration loss and high-temperature and high-pressure (HTHP) filtration loss after hot rolling of 4.2 and 22.0 mL, respectively. At high temperatures, the degradation of the polymer composite releases nanoparticles, which enhance the density of the filter cake, allowing for adjustable and enhanced control of filtration performance of drilling fluids under high-temperature and high-salty conditions.
研究领域:
石油工程
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
ACS Applied Materials & Interfaces
·
2024
·
IF 8.3
Siyuan Diao,Lili Meng,Christian Mark Pelicano,Jiajia Huang,Zhihong Tian,Feili Lai,Tianxi Liu,Shaokui Cao
Photothermal responsive hydrogels are widely used in bionic soft actuators due to their remote-controlled capabilities and flexibility. However, their weak mechanical properties and limited responsiveness hinder their potential applications. To overcome this, we developed an innovative laponite/MXene/PNIPAm (LxMyPN) nanocomposite hydrogel that is mechanically robust and exhibits excellent photothermally responsive properties based on abundant hydrogen bonds. Notably, laponite clay is used as a co-cross-linking agent to improve the mechanical properties of LxMyPN hydrogel, while MXene nanosheets are added to promote the photothermal responsiveness. The resulting L3M0.4PN nanocomposite hydrogel exhibits enhanced mechanical properties, with a compressive strength of 0.201 MPa, a tensile strength of 90 kPa, and a fracture toughness of 27.25 kJ m–2. In addition, the L3M0.4PN hydrogel displays a deswelling ratio of 73.6% within 60 s and experiences an excellent volume shrinkage of 82.4% under light irradiation. Furthermore, hydrogel actuators with fast response behaviors are constructed and employed as grippers capable of grasping and releasing target objects. Overall, this high-strength and fast-responsive hydrogel actuator is beneficial to paving the way for remote controlled soft robots.
研究领域:
材料科学
·
生物仿生学
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产品关联
DOI
PubMed
高影响因子
FIBERS AND POLYMERS
·
2018
·Vol. 19
·期 3
·477-488
·
IF 1.353
Peng Qingyan,Xu Pengjun,Xiao Shili
Fabrication of porous polymer membrane with controlled drug release and efficient antibacterial performances is of great interest in biomedical fields. In this study, Laponite (LAP) nanodisks were first used to encapsulate a model antibiotic drug, tetracycline hydrochloride (TCH). Then, drug-loaded LAP nanodisks with an optimized loading efficiency (85.3 %) were mixed with poly(L-lactic acid) (PLLA) polymer to form drug-loaded composite porous membrane via solvent coasting. The structure, morphology and swelling property of the porous membranes formed with varied solvent ratio of methylene dichloride (DCM) and dimethyl formamide (DMF) in the mixture solvent were characterized using scanning electron microscopy (SEM), Fourier transform infrared spectroscopy and swelling test. In vitro drug release behavior, the cytotoxicity and the antibacterial activity of drug-loaded composite membranes were evaluated. Results showed that the TCH release was dependent on the physical structure of PLLA membrane and the presence of LAP nanodisks effectively weakened the initial burst release of TCH, and improved the sustained release property of porous PLLA membrane. The released TCH of TCH/LAP/PLLA 3:1 and TCH/LAP/PLLA 4:1 was 10.0 % and 5.3 % within initial 1 h, respectively. More importantly, the porous TCH/LAP/PLLA membrane was cytocompatible and displayed considerable antibacterial activity, solely associated with the loaded TCH drug, confirming its potential utility in wound dressings and tissue engineering.
研究领域:
生物医学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
CARBOHYDRATE POLYMERS
·
2019
·
IF 6.044
Guodong Li,Dehai Yu,Zhaoping Song,Huili Wang,Wenxia Liu
It is a significant challenge to reduce the sheet formation time and simultaneously sustain high transparency and good formation of nanostructured paper made of cellulose fibrils. In this study, a new strategy was developed for expediting the filtration but avoiding the flocculation of cellulose fibrils by using polyvinylpyrrolidone (PVP) and Laponite as dispersants to reduce the viscosity of the cellulose fibril aqueous dispersion. By adding 0.5 % PVP and 0.2 % Laponite to the cellulose fibril dispersion, the sheet formation time was reduced from 135.3–53.0 min, and the transmittance of the nanostructured paper was increased from 82.8%–89.8 %. The addition of PVP and Laponite significantly reduced the roughness and density but improved the tensile strength of the nanostructured paper. This study provides an approach for simultaneously improving the drainability, transparency, tensile strength, and smoothness of cellulose nanostructured paper made of cellulose fibrils.
研究领域:
材料科学
·
化学工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）