ACS Applied Nano Materials
·
2020
·
IF 0
Junshan Hu,Ruonan Wang,Rangrang Fan,Fengyi Wang,Huiyu Xiong,Zhenghu Huang,Lixin Liu,Hao Fu
Here, we report a nanocomposite with excellent photothermal performance promising for photothermal treatment. This nanocomposite is prepared by linking Au nanorods (NRs) to NaGdF4:18% Yb3+, 2%Er3+@NaYF4 core–shell upconversion nanoparticles (UCNPs) with bridging of polyethylene glycol molecules. Solutions with the composite nanoparticles can be heated by the irradiation of a near-infrared 980 nm laser, and the photothermal effect in terms of temperature rise can reach 21.3 °C with excitation power density as low as 0.090 W/cm2. This highly effective photothermal performance is attributed to coincidence of the emission band of the UCNPs and the absorption band of the Au NRs, which facilitates the light-to-heat conversion. The structure of the composite and the concentration of the Au NRs in the solution are also optimized through the emission intensity, green-to-red intensity ratio, and the photothermal effect in this work. Compared with previous research studies, the strength in the lower irradiation power density makes the nanocomposite promising for further photothermal treatment and temperature sensing.
✓ 已验证
产品关联
DOI
Nanoscale
·
2018
·Vol. 10
·期 40
·19031-19038
·
IF 7.233
Qiuhong Min,Lei Zhao,Yushuang Qi,Jing Lei,Wenbo Chen,Xuhui Xu,Dacheng Zhou,Jianbei Qiu,Xue Yu
An amorphous layer acting as a quenching center at the surface of oleic acid-capped NaGdF4:Yb3+/Tm3+ nanoparticles is observed directly, which can be reconstructed via a novel post-chemical annealing process. The amorphous phase of the surface layer of NaGdF4:Yb3+/Tm3+ nanoparticles gradually crystallizes as the post-chemical annealing temperature increases; meanwhile, the good dispersibility of the as-obtained nanoparticles is maintained. The reduction of surface defects and higher local symmetry of the crystal field environment around the doped rare-earth ions contribute to drastically increased up-conversion (UC) emission intensity of the NaGdF4:Yb3+/Tm3+ nanoparticles. In particular, the blue emission of Tm3+ at 450 nm enhances 10-fold after the post-chemical annealing process at 250 °C compared with the counterpart without further surface-state treatments. The color gamut of well-crystallized NaGdF4:Yb3+/Tm3+ with a modified surface covers the blue to yellow region in CIE chromaticity coordinates via a non-steady-state UC process. The results indicate that the surface states of these UC nanoparticles can be feasibly improved via the post-chemical annealing process without encouraging agglomeration, which further optimizes their UC properties for practical applications.
研究领域:
材料科学
·
光学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
NANO
·
2014
·
IF 1.26
HUI LI,CHUANXI WANG,YINGNAN JIANG,ZHANCHEN CUI,QUAN LIN
Lanthanide-doped luminescent nanoscale materials have great potential applications in biological researches. Herein, we reported a novel and mild method for one-step synthesis of chitosan/ NaGdF 4 : Eu 3+ nanocomposites. The luminescent Eu 3+ ions and magnetic resonance imaging (MRI) contrast agent Gd 3+ ions were incorporated to these biocompatible nanocomposites. The resultant nanocomposites exhibited strong fluorescence and attractive magnetic features. The nanocomposites also have pure hexagonal phase with uniform size of about 65 nm. FT-IR spectra revealed that these nanocomposites were successfully coated by hydrophilic chitosan, whose amine groups conferred the nanocomposites excellent dispensability in aqueous solution. Besides, the MTT assay and laser confocal microscopy images have confirmed the good biocompatibility of the nanocomposites. These results indicated that the as-prepared nanocomposites could be used as an excellent targeted imaging agent in biological fields.
研究领域:
生物医学工程
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF WUHAN UNIVERSITY OF TECHNOLOGY-MATERIALS SCIENCE EDITION
·
2022
·Vol. 37
·期 3
·393-398
·
IF 1.271
Hou Huayu,Gan Lin,Wang Youfa,Wang Wei
Nd 3+ -doped NaGdF 4 : Yb, Tm nanocrystals were synthesized by an improved high-temperature thermal decomposition method, and the effects of doping concentrations on the crystal structure, phase composition, and upconverted fluorescence intensity were also investigated. The results reveal that the introduction of Nd 3+ ions does not cause the transformation of the crystal phase, but induce the change of the unit cell parameters. Meanwhile, the fluorescence intensity of the synthesized nanocrystals when co-doped with 3 mol% Nd 3+ is the strongest under the excitation of 980 nm laser, which is 3.9 times that of the Nd 3+ -free doped nanoparticles, and the average size is 62.9 nm. And it is located in the blue area of the CIE coordinate diagram, and the corresponding color purity is 91.81% under the same experimental conditions. The resulting nanocrystals show the potential as excellent fluorescence labeling and in vivo imaging probes.
✓ 已验证
产品关联
DOI
高影响因子
Journal of Materials Chemistry C
·
2022
·Vol. 10
·期 13
·5109-5115
·
IF 8.067
Tao Pang,Yanyan Wu,Yujian Zhang,Ronghua Jian,Junwen Mao,Hong Wang,Hai Guo
Although much effort has been focused on thermally enhanced upconversion (UC) luminescence, it remains a challenge to maintain or even enhance the UC luminescence of NaLnF4-based phosphors (Ln = Y, Gd, Lu) using a surface-independent strategy. In this work, we demonstrate that the effect of temperature on UC luminescence in NaGdF4:Nd3+/Yb3+/Er3+ nanocrystals is strongly dependent on the exciting wavelength. When excited using 808 nm radiation, the UC luminescence exhibits good resistance to thermal quenching. The reason is that, in this situation, the negative effect of multi-phonon decay can be fully compensated by the thermal enhancement in the transition cross-section and in energy-transfer rate. Our research reports a novel strategy for the anti-thermal quenching of upconversion luminescence, which is potentially applicable in the design of dynamic UC anti-counterfeiting as well as in NIR-I-responsive thermometers and nanoheating.
✓ 已验证
产品关联
DOI
高影响因子
TRANSACTIONS OF NONFERROUS METALS SOCIETY OF CHINA
·
2020
·
IF 2.615
Yin CHEN,Shao-wen XIE,Chao TONG,Hai-hu TAN,Li-jian XU,Na LI,Jian-xiong XU
Novel hydrophilic NaYF 4 :Yb 3+ ,Tm 3+ @NaGdF 4 :Ce 3+ ,Eu 3+ double-jacket microtubes (DJMTs) with upconversion/ downconversion dual-mode luminescence were designed and prepared through epitaxial growth of NaGdF 4 :Ce 3+ , Eu 3+ shell onto the NaYF 4 :Yb 3+ ,Tm 3+ microtube via poly(acrylic acid) (PAA) mediated hydrothermal method. It is demonstrated that PAA ligand played an important role in guiding the direct growth of NaGdF 4 :Ce 3+ ,Eu 3+ shell onto the surface of NaYF 4 :Yb 3+ ,Tm 3+ parent microtubes. The growth of NaGdF 4 :Ce 3+ ,Eu 3+ shell experienced a crystal phase transition from β -NaGdF 4 and β -NaYF 4 mixture to β -NaYF 4 @NaGdF 4 composite crystal, and morphology evolution from mixture of β -NaGdF 4 :Ce 3+ ,Eu 3+ nanorods and β -NaYF 4 :Yb 3+ ,Tm 3+ microtubes to NaYF 4 :Yb 3+ ,Tm 3+ @NaGdF 4 : Ce 3+ ,Eu 3+ DJMTs. The formation mechanism of DJMTs was the dissolution−renucleation of β -NaGdF 4 :Ce 3+ ,Eu 3+ nanorods and the growth of β -NaGdF 4 :Ce 3+ ,Eu 3+ shell via the classical Ostwald ripening mechanism. The as-prepared DJMTs could exhibit blue upconversion and red downconversion luminescence, which was further made into environmentally benign luminescent inks for creating highly secured and fluorescent-based anti-counterfeiting patterns via inkjet printing.
✓ 已验证
产品关联
DOI
高影响因子
RSC Advances
·
2019
·Vol. 9
·期 31
·18070-18075
·
IF 3.049
Yabing Li,Fujin Li,Yanan Huang,Haiyan Wu,Jian Wang,Jin Yang,Qingbo Xiao,Hongzhen Lin
Small-sized lanthanide-doped nanoparticles (NPs) exhibiting superior near-infrared (NIR) luminescence properties are highly desired for bioimaging applications. Herein, Fe3+ ions are codoped in NaGdF4:Nd3+ nanocrystals via a simple coprecipitation method, which can simultaneously reduce the particle size and enhance the downconverting NIR luminescence of the NPs. The NIR luminescence intensity reaches the maximum for the obtained sub-5 nm NPs when the doping concentration of Fe3+ is tuned to 20 mol%, which is ∼1.7 times higher than that of the pristine 8.7 nm NPs without Fe3+ doping. After being modified with targeting molecules, the ultra-small NaGdF4:Nd3+,Fe3+ NPs were successfully applied as luminescent probes for targeted NIR imaging of tumors in biological tissues. Moreover, they also show great potential as a high contrast agent for T2-weighted MRI imaging.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF LUMINESCENCE
·
2022
·
IF 4.171
Junshan Hu,Fengyi Wang,Wei Jin,Changchun Ding
Upconversion nanoparticles (UCNPs) have great potential applications in biological imaging, medical treatment and optical sensing. However, the development of an inorganic-organic hybrid fluorescent probe to accurately detect noxious ions and scientifically assess irritation in vivo remains a challenge. Herein, we demonstrate a fluorescent nanoprobe for detecting nitrites (NO 2 − ) and assessing the irritation in jellyfish cell. The nanoprobe was assembled by linking neutral red to the surface of polyethylene glycol (PEG) modified NaGdF 4 :Yb,Er@NaYF 4 core/shell nanoparticles. The nanoprobe could efficiently capture the NO 2 − in jellyfish and simultaneously visualize the process. It's known that the intensity ratio of green to red emission (IRGRE) of neutral red modified upconversion nanoparticles increases linearly with the amount of NO 2 − increasing. Moreover, the irritation of NO 2 − was assessed in jellyfish cells using neutral red modified fluorescent nanoprobe based on cell imaging and spectrum signals, that NO 2 − has irrecoverable injury to the cells. This work based on dye-modified upconversion luminescence nanoprobe is expected to shed further light on the biological analysis and detection of ions.
✓ 已验证
产品关联
DOI
高影响因子
Nanomaterials
·
2022
·Vol. 12
·期 5
·728
·
IF 5.719
Wei Zhang,Yang Zang,Yanli Lu,Jinghui Han,Qingyun Xiong,Jinping Xiong
In this study. a novel near-infrared fluorescent-driven contrast agent (Ag-doped NaYF4:Yb3+/Er3+@NaYF4:Nd3+@NaGdF4) was synthesized using a coprecipitation-hydrothermal-solvothermal-solvothermal (CHSS) method. The results shows that hexagonal NaYF4:Yb3+/Er3+with a diameter of 300 nm was successfully synthesized by the CHSS method. The new contrast agent was characterized using scanning electron microscopy, fluorescence spectrometry, transmission electron microscopy, energy-dispersive spectrometry and ultraviolet-visible light diffuse reflectance absorption spectroscopy. Even at low concentrations (0.2 M), this proposed contrast agent can be excited by near-infrared light with a wavelength of 980 nm and emits a dazzling green light with a wavelength of 540 nm, and the comparison of the luminescence intensity proves that doping with silver increases the luminescence intensity of the upconverted nanomaterial by nearly 13 times based on the calculated quantum yield. TEM images show the successful preparation of silver nanoparticles with a diameter of 30 nm, and the energy spectrum shows the successful doping of silver nanoparticles and the successful preparation of the core-shell structure of NaYF4:Yb3+/Er3+@NaYF4:Nd3+@NaGdF4. Furthermore, the mechanism of the increased luminous intensity has been studied using simulation calculations. Finally, cytotoxicity tests were used to test material which was modified by 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[amino(polyethylene glycol)-2000] (DSPE-PEG2K), and the biocompatibility was significantly improved, meeting the standard for biological applications.Keywords:upconversion;near-infrared;intensity;in vivo imaging
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CHEMICAL RESEARCH IN CHINESE UNIVERSITIES
·
2019
·Vol. 35
·期 3
·537-541
·
IF 1.071
Huang Sa,Han Qinghe,Wang Lei,Gong Tingting,Yuan Qinghai
Polyethylene glycol modified(PEGylated) NaGdF 4 (PEG-NaGdF 4 ) nanoparticles as a novel T 1 -weighted magnetic resonance imaging(MRI) contrast agent was successfully constructed by a one-pot hydrothermal synthesis method. Because of the functionalization of PEG, the nanoprobes had excellent dispersity, excellent stability and high biocompatibility. More importantly, the as-prepared PEG-NaGdF 4 nanoprobes revealed the high longitudinal relaxivity value and prominent T 1 -weighted MRI contrast performance, which was superior to the commercial MRI contrast agents. With the facile synthesis, excellent dispersity, outstanding stability, remarkable contrast performance and high biocompatibility, the PEGylated NaGdF 4 nanoparticles brought more opportunities to the new generation of nanoparticulate-based T 1 -weighted MRI contrast agents in clinic.
研究领域:
纳米技术
·
材料科学
·
生物医学工程
·
磁共振成像
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2024
·
IF 5.8
Guangdong Wu,Juanqin Xue,Zhaoyuan Cao,Yanyan Zhou,Qiang Bi,Yan Zhao,Zhihua Leng
Constructing heterojunction photocatalysts that can make additional utilization of near-infrared (NIR) light has been a global scientific problem and has gained widespread research interest. Upconversion nanoparticles (UCNPs) collaborate with semiconductors to construct UCNPs-based photocatalysts that are used to improve solar energy utilization. In this work, the as-prepared UCNPs-based photocatalysts consisting of NaGdF 4 :Yb 3+ /Er 3+ (NGFYE) and bismuth oxyiodide (BOI) are synthesized by chemical epitaxial growth method and in-situ calcination process. The crystalline phase , morphology, optical and electrochemical properties of NGFYE@BOI samples are investigated in detail. Besides, Bi 4 O 5 I 2 /Bi 5 O 7 I Z-type heterojunction is confirmed by EPR test. Moreover, the photocatalytic elimination of tetracycline hydrochloride (TCH) and its photocatalytic mechanism by NGFYE@BOI samples are explored. This work may provide a promising idea for the efficient and controlled synthesis of UCNPs-based photocatalysts, which will contribute to the future utilization of solar energy.
研究领域:
材料科学
·
环境科学
·
化学
✓ 已验证
产品关联
DOI
高影响因子
MOLECULES
·
2026
·Vol. 31
·期 19
·3412
·
IF 5.1
Xinyao Su,Wen Guo,Qunming Zhou,Tingting Xie,Lingyan Wu,Shangyang Wang,You Fu,Shurong Li,Wei Peng,Peijun Meng
Cancer theranostics urgently demands multifunctional nanomaterials capable of simultaneously enabling high-sensitivity imaging and multimodal synergistic therapy. In this study, a three-layer core–shell nanocomposite, NaYF4:Yb,Tm@NaGdF4:Eu@NH2-MIL-53(Fe), was designed and synthesized. The NaYF4:Yb,Tm nanoparticle core provides upconversion luminescence upon near-infrared (NIR) excitation and can serve as an excitation source for photodynamic therapy. An epitaxially grown NaGdF4:Eu intermediate shell was introduced to enhance luminescence and provide T1-weighted magnetic resonance imaging (MRI) capability. The outermost NH2-MIL-53(Fe) metal–organic framework shell was subsequently coated to provide potential chemodynamic therapy (CDT) capability. The effects of the Eu3+doping concentration, reaction temperature, reaction time, and oleic acid (OA)/1-octadecene (ODE) ratio on the anisotropic growth into a dumbbell-like morphology were examined to determine the optimal conditions. Under the optimal conditions (10 mol% Eu3+, 300 °C, 60 min, OA/ODE = 4:16), core–shell nanocrystals with regular morphology, uniform size, and the strongest upconversion luminescence were obtained. Polyvinylpyrrolidone (PVP)-mediated surface functionalization successfully induced the in situ growth of the NH2-MIL-53(Fe) outer shell, thereby constructing a three-layer core–shell nanocomposite as a potential theranostic platform. Various characterizations confirmed that the resulting composite integrates upconversion luminescence, paramagnetism, and hydroxyl radical generation capability, suggesting potential for NIR-driven dual-modal imaging-guided synergistic therapy.
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）