Materials Today Nano
·
2025
·
IF 8.2
Teng Zhou,Daohai Zhang,Kunlan Diao,Jiajia Du,Yupeng Hu,Zhi Lei,Dongju Liu,Shan Liu,Shuhao Qin
With the widespread popularity of digital technology, electromagnetic interference(EMI) has become a new type of pollution that endangers electronic equipment and biological systems. In this paper, MWCNTs@TiO 2 composite materials were prepared by the hydrothermal synthesis method and then added into the three dimensional framework constructed by PAM (polyacrylamide) and PEG (polyethylene glycol) to obtain hydrogels with EMI functionality. It was found that in the M@T/PAM-4 (MWCNTs@TiO 2 /PAM-4) hydrogel, due to the fact that TiO 2 particles were loaded on the surface of MWCNTs, its cross section presented a granular shape. As the content of MWCNTs increased, the EMI SE T of the hydrogel increased, with the M@T/PAM-4 hydrogel reaching 29 dB. The electrical conductivity and mechanical properties also increased accordingly. Compared with the pure PAM hydrogel, they were respectively improved by 626 % and 24.5 %, which was attributed to the formation of a conductive network by MWCNTs and the enhancement of interfacial polarization, etc. Meanwhile, the water retention rate of the M@T/PAM-4 hydrogel could still reach 34.1 % after 8 h. Moreover, it also had a relatively high water content of 69.08 %. Therefore, This improves the application value and development prospects of the hydrogel in fields such as Electromagnetic (EM) shielding.
研究领域:
材料科学
·
环境科学
·
电子工程
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产品关联
DOI
高影响因子
eLife
·
2025
·
IF 0
Lin Yan,Litao Wu,Timothy D Wiggin,Xiaojuan Su,Wei Yan,Hailiang Li,Lei Li,Zhonghua Lu,Yuantao Li,Zhiqiang Meng,Fang Guo,Fan Li,Leslie C Griffith,Chang Liu
Sleep disturbances are associated with poor long-term memory (LTM) formation, yet the underlying cell types and neural circuits involved have not been fully decoded. Dopamine neurons (DANs) are involved in memory processing at multiple stages. Here, using both male and female flies, Drosophila melanogaster, we show that, during the first few hours of memory consolidation, disruption of basal activity of a small subset of protocerebral anterior medial DANs (PAM-DANs), by either brief activation or inhibition of the two dorsal posterior medial (DPM) neurons, impairs 24 h LTM. Interestingly, these brief changes in activity using female flies result in sleep loss and fragmentation, especially at night. Pharmacological rescue of sleep after manipulation restores LTM. A specific subset of PAM-DANs (PAM-α1) that synapse onto DPM neurons specify the microcircuit that links sleep and memory. PAM-DANs, including PAM-α1, form functional synapses onto DPM mainly via multiple dopamine receptor subtypes. This PAM-α1 to DPM microcircuit exhibits a synchronized, transient, post-training increase in activity during the critical memory consolidation window, suggesting an effect of this microcircuit on maintaining the sleep necessary for LTM consolidation. Our results provide a new cellular and circuit basis for the complex relationship between sleep and memory.
研究领域:
神经科学
·
行为生物学
·
睡眠研究
·
记忆机制
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产品关联
DOI
JOURNAL OF APPLIED POLYMER SCIENCE
·
2025
·
IF 2.8
Yun Wang,Heng Li,Jinming Li,Wei Zhang,Chengwei Wu
Repairing and regenerating articular cartilage remains a significant challenge, primarily due to its limited self-healing capability. Hydrogel has emerged as a promising candidate due to its resemblance to extracellular matrices. A porous hydrogel of an appropriate size can facilitate cell growth and integrate into the host tissue. However, the presence of pores in hydrogels will significantly reduce mechanical properties, posing challenges in replacing the load-bearing function of articular cartilage. Here, a porous hydrogel was prepared through a gas forming method based on a triple-network hydrogel system of poly(vinyl alcohol) (PVA)-polyacrylamide (PAM)-agarose (AG), with a pore size of 100–200 μm. The hydrogel exhibits a compressive modulus of up to 0.79 MPa and a tensile modulus of up to 0.35 MPa, falling within the reference range of articular cartilage. Furthermore, the porous hydrogel exhibits good creep resistance properties. These results suggest that the porous hydrogels with strong mechanical properties hold promise as a replacement material for articular cartilage.
研究领域:
生物材料学
·
再生医学
·
组织工程学
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产品关联
DOI
高影响因子
APPLIED THERMAL ENGINEERING
·
2024
·
IF 6.1
Qing-Kai Zhu,Hong-Bei He,Chao-Chen Cai,Ting-Ting Li,Ching-Wen Lou,Jia-Horng Lin,Hai-Tao Ren
Evaporative cooling and radiative cooling are considered to be energy-saving and environmentally friendly cooling technologies. However, the evaporative cooling system requires complex external water supply equipment, and the radiative cooling is susceptible to weather, which hinder the practical application. Herein, TiO 2 was used as the photo-initiator and spectral regulator, and a hydrogel integrating radiative cooling and evaporative cooling was prepared by combining photopolymerization with semi-acidification sol–gel transition method. The obtained hydrogel shows good mechanical strength (elongation at break > 600 %, and fracture stress > 200 kPa), high visible reflectance (>80.0 %) and emissivity in atmospheric window band (>90.0 %). At the same time, due to the introduction of hygroscopic agent CaCl 2 , it can replenish water itself at night. In outdoor experiment, the hydrogel showed a cooling effect of up to 12.5 °C, showing a significant potential for reducing energy consumption in cooling applications. In addition, the synthesis process of hydrogel is green, which aligns with environmental safety and sustainability goals. This study provides a new strategy for developing efficient, environmentally friendly, and low-cost passive coolers to reduce the global energy burden.
研究领域:
材料科学
·
环境科学
✓ 已验证
产品关联
DOI
高影响因子
SOFT MATERIALS
·
2019
·
IF 0.973
Minying Wang,Le Luo,Lihua Fu,Hua Yang
Polyacrylamide/sodium alginate (PAM/SA) hydrogel was prepared from sodium alginate (SA) and acrylamide (AM) by covalently cross-linking. Temporary shape double network PAM/SA hydrogels were obtained by ionic cross-linking formed by complexation of SA and six metal cations (Fe3+, Cu2+, Ag+, Ca2+, Ni2+, and Co2+), among the PAM/SA—Fe3+ hydrogels has the best shape fixity ratio (83%). When the hydrogel is placed in different recovery liquids (sodium citrate, EDTA, sulfuric acid, and potassium carbonate), the shape recovery ratio (98.9%) is the best in sodium citrate solution, and the recovery time (182 s) of the hydrogel is the shortest. In general, Fe3+, Cu2+, and Ag+ are suitable for the construction of ionic-shape memory hydrogels. The PAM/SA hydrogels also exhibited excellent adjustable mechanical properties by changing metal cations and soaking time. The strategy could broaden the construction of ion-responsive shape-memory hydrogels.
研究领域:
材料科学
·
生物医学工程
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产品关联
DOI
高影响因子
Processes
·
2022
·Vol. 10
·期 2
·402
·
IF 3.352
Ziyang Zheng,Qian Wu,Shengyang Zhong
In this work, polyacrylamide (PAM) was first used in the loading of heteropoly acids, and then the HPM/PAM-n catalyst was synthesized by simple reaction. The FTIR and SEM measurements showed that the HPM/PAM-n (n = 10,000, 20,000, 30,000) was successfully synthesized. In addition, the HPM/PAM-n effect on desulfurization was measured, which showed the optimal desulfurization efficiency. The optimal process condition for HPM/PAM-10000 desulfurization was optimized by a single-factor experiment. The optimal condition was as follows: The temperature was 60 °C, the amount of the catalyst was 0.2 g, the oxygen to sulfur ratio was 16, and the reaction time is 100 min. The catalyst was suitable for recycled use, and the desulfurization efficiency was high after 10 times. In the end, the oxidative desulfurization mechanism was put forward.Keywords:PAM;desulfurization;heteropoly acid;recycle use
研究领域:
化学工程
·
环境科学
✓ 已验证
产品关联
DOI
高影响因子
Frontiers in Pharmacology
·
2018
·
IF 3.831
Tsai Hsiang-I,Jiang Lijuan,Zeng Xiaowei,Chen Hongbo,Li Zihuang,Cheng Wei,Zhang Jinxie,Pan Jie,Wan Dong,Gao Li,Xie Zhenhua,Huang Laiqiang,Mei Lin,Liu Gan
The clinical applications of platinum-based antitumor agents are still largely limited by severe side effects as well as multidrug resistance (MDR). To solve these problems, we developed an 1,2-diaminocyclohexane-platinum(II) (DACHPt)-loaded nanoparticle (NP-TPGS-Pt) by self-assembly of poly(amidoamine)-polyglutamic acid-b-D-α-tocopheryl polyethylene glycol 1000 succinate (PAM-PGlu-b-TPGS) and DACHPt. NP-TPGS-Pt showed robust stability and pH-responsive DACHPt release profile in vitro similar to the PEG-containing nanoparticle (NP-PEG-Pt). Meanwhile, in contrast with NP-PEG-Pt, NP-TPGS-Pt exhibited efficient nanoparticle-based cellular uptake by the Pt-resistant A549/DDP human lung cancer cells and caused much more cytotoxicity than free Oxaliplatin and NP-PEG-Pt. Finally, this NP-TPGS-Pt was proved to perform outstanding inhibition of Pt-resistant tumor growth, much superior than free Oxaliplatin and NP-PEG-Pt. Thus, this NP-TPGS-Pt provides a novel powerful nanomedicine platform for combatting multidrug resistant cancer.
研究领域:
药学
·
肿瘤学
·
纳米医学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ENERGY & FUELS
·
2026
·
IF 6
Liu Jiahao,Dai Wei,Song Xinwei,Li Wenjian,Xu Xiancheng,Zhao Yingcan,Ge Mingming,Wang Yang,Liu Tong,Zhao Siyuan
Hydrogel electrolytes are central to flexible Zn-air
batteries
(FZABs) because they determine the ion transport and interface chemistry
of the cathode and anode. However, the dense hydrogel networks restrict
ion migration and lead to an increased level of polarization during
battery operation. Herein, a facile additive strategy is developed
by introducing urea, a chaotropic agent, into a dual-network polyacrylamide
(PAM)-agar hydrogel. The dual-network hydrogel ensures mechanical
robustness, while the urea untangles the polymer network and generates
a porous structure with more ion-transport channels. The optimized
PAM-agar hydrogel with 2 M urea delivers an 11.2% higher ionic conductivity
than the urea-free counterpart and improves water retention ability.
As a result, the assembled FZAB exhibits an open-circuit voltage of
1.408 V, a peak power density of 80.0 mW cm –2 , stable
discharge for 130 h, and 320 charge–discharge cycles. This
work demonstrates that chaotropic additive engineering is an effective
route to regulate hydrogel ion transport microenvironments for durable
FZABs.
✓ 已验证
DOI
高影响因子
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
·
2024
·Vol. 35
·期 29
·1-11
·
IF 2.8
Wang Junru,Xia Guoxiang,Xia Longquan,Chen Yunfeng,Li Qinyuan,Zeng Hong,Yang Weiguo,Du Yongjie,He Wei,Chen Yuanming
Flexible wearable devices for health monitoring require continuous wear throughout the day, making flexible pressure sensors a critical component that has attracted significant attention. Polyacrylamide (PAM) and polyvinyl alcohol (PVA) were used as hydrogel substrate materials to fabricate wearable devices with on-the-go wearability. Helical carbon nanotubes (HCNTs) were employed as conductive fillers, with silver nanoparticles (AgNPs) deposited on their surface to enhance conductivity. The conductive HCNT/AgNPs fillers bonded with the PVA/PAM substrate via metal–hydrogen bonds, metal complexes, and Ag–O bonds. This bonding enhanced the binding strength of the gel and accelerated polymerization. Pressure sensors packaged within the hydrogel exhibited high sensitivity of 0.118 kPa –1 to minor deformations and high sensitivity of 0.0141 kPa –1 to regular deformations, providing a flexible pressure sensor with high sensitivity and fast response. This innovation delivers a highly sensitive and fast-responding flexible pressure sensor, paving the way for advanced flexible wearable electronic devices.
研究领域:
材料科学
·
生物医学工程
✓ 已验证
产品关联
DOI
高影响因子
IEEE SENSORS JOURNAL
·
2025
·
IF 4.5
Yue Zhang,Ao Lan,Yuanhao Xia,Xiangyu Yin,Bingwei He,Pengli Zhu
The advancement of hydrogel-based epidermal sensors that integrate multifunctionality, high transparency, rapid processing, and heightened sensitivity is of significant interest. Herein, we present an efficient approach for the fabrication of flexible dual-mode epidermal sensors through the ultraviolet (UV)-curing 3D printing of polyacrylamide (PAM)-based ionic hydrogels. The hydrogel precursor incorporates sodium dodecyl sulfate (SDS) monomers to augment the water dispersibility of the 2,4,6-trimethylbenzoyl-diphenylphosphine oxide (TPO) photoinitiator, thereby substantially increasing the photocuring efficiency of the ionic hydrogel. As a result, distinctive surface microstructures of PAM-based ionic hydrogels can be engineered for sensors with varying sensing modalities to improve detection performance. The piezoelectric tactile sensor, incorporating a concentric ring microstructure, demonstrates a sensitivity coefficient of 1.39 mV·kPa-1. Conversely, the resistive strain sensor, characterized by a high-density reticular hollow structure, exhibits the highest gauge factor of 24.87. Furthermore, each sensor modality demonstrates excellent temporal response and stability, confirming its applicability in motion monitoring and Morse code transmission.
研究领域:
材料科学
·
生物医学工程
·
传感器技术
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产品关联
DOI
高影响因子
ACS Applied Energy Materials
·
2019
·
IF 0
Chuan-Shan Hu,Hui-Juan Li,Jia-Yun Wang,Abdul Haleem,Xi-Chuan Li,Muhammad Siddiq,Wei-Dong He
Lacking clean water has become a matter of urgency and harvesting solar energy for water evaporation is an efficient solution. Loading photothermal materials into porous and hydrophilic matrix prominently facilitates the water evaporation efficiency. In this work, cryopolymerization was adopted first to fabricate macroporous and hydrophilic matrix–cryogel of polyacrylamide (PAM) while reduced graphene oxide (rGO) was hybridized during the fabrication with thermal reduction of graphene oxide (GO). Inspired by the transpiration of natural mushroom, the solar-heating device was integrated with the stipe of PAM cryogel, which expedited the transport of water from the water reservoir to the pileus and the elimination of heating energy loss, and the pileus composed of rGO/PAM hybrid cryogel, which enabled the high efficiency of solar light absorption and solar-heating conversion. Such a mushroom-like device achieved rapid water vapor generation and high overall efficiency of solar-heating evaporation under one-sun illumination. As well, this mushroom-like device exhibited the identical practicability of solar-heating evaporation for the different water sources such as the wastewater containing salt, surfactant, or oil, compared with pure water. Within 10 cycles, those mushroom-like rGO/PAM hybrid cryogels retained the analogous solar-heating evaporation performance. The mushroom bioinspiration and cryopolymerization would afford a novel and convenient route for highly efficient solar-heating water evaporation.
研究领域:
材料科学
·
环境科学
✓ 已验证
产品关联
DOI
MACROMOLECULAR MATERIALS AND ENGINEERING
·
2022
·Vol. 307
·期 10
·2200251
·
IF 4.402
Xinxin Liu,Minmin Chang,Hui Zhang,Junli Ren
A variety of 0D nanoparticles (MgO, ZnO, Al 2 O 3 , Fe 2 O 3 , SiO 2 , and TiO 2 ) as nanofiller materials are introduced into polyacrylamide- g -carboxymethyl xylan (PAM- g -CMX) composite hydrogel. The effects of different shapes and different sizes of nanoparticles on the properties of hydrogels are investigated. The properties of nanocomposite hydrogels are analyzed by Fourier transform infrared spectroscopy, X-ray diffraction, scanning electron microscopy (SEM), rheological analysis, swelling analysis, and mechanical test. Composite hydrogels with nanoparticles exhibit uniform pore structure and smaller pore size in SEM images, resulting in a reduced equilibrium swelling ratio. In addition, the results show that the hydroxyl groups on the surface of the nanoparticles forms hydrogen bonds with the amino groups and carboxyl groups in the PAM- g -CMX cross-linked network which improve the mechanical strength of nanocomposite hydrogels. The hydrogel with 20 nm MgO has the maximum compressive strength (550.9 kPa), tensile strength (28.6 kPa), and the longest elongation (813%) owing to the spherical shape and small size of MnO (20 nm). The hydrogels with nanoparticles maintain the originated 90% strength after 30 cycles of compressive test. The hydrogels with nanoparticles will offer new insights for xylan application.
研究领域:
材料科学
·
聚合物化学
·
纳米技术
·
复合材料
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）