Biomedical Materials
·
2023
·Vol. 18
·期 6
·065006
·
IF 4
Jing Zhang,Miaomiao Hu,Changchun Wen,Jian Liu,Fang Yu,Juan Long,Xiang-Cheng Lin
Single tumor treatment method usually has some defects, which makes it difficult to achieve good therapeutic effect. The ingenious combination of multiple tumor treatment methods on a single nanoplatform to achieve multifunctional treatment can effectively improve the efficiency of treatment. The targeted modification of nanomaterials can augment the precision of nanotherapeutic drugs in tumor treatment. Herein, a multifunctional nanoplatform (CeO2@CuS@PDA-FA) based on cerium dioxide nanoparticles engineered with copper sulfide (CeO2@CuS) has been constructed for synergistic photothermal therapy (PTT) and chemodynamic therapy (CDT). The CeO2@CuS were coated using polydopamine (PDA), and the modification of PDA surface by folic acid, in order to achieve the targeted effect for tumors. The localized hyperthermia induced by PTT can further improve the CDT efficiency of the nanoplatform, leading to a PTT/CDT synergistic effect. The nanoplatform possessed the capability of cancer cell-targeted and achieved better therapeutic efficacy in vitro. This work provided a new strategy for combined multifunctional theranostic platform and shows strong potential in practical applications.
研究领域:
纳米医学
·
癌症治疗
·
生物材料
✓ 已验证
DOI
高影响因子
JOURNAL OF MATERIALS SCIENCE
·
2024
·Vol. 59
·期 20
·9165-9181
·
IF 3.5
Zhao Chen,Yang Gang,Luo Qianxue
The PDA/PEI modification technology is commonly employed to improve the resistance to membrane fouling of polymeric membranes used in the treatment of oily wastewater. Nevertheless, the surface characteristics of membrane materials frequently restrict the implementation of the modification technique in terms of both the amount and speed of deposition. The hydrophobic membranes, such as PVDF and PTFE, have a surface with very low surface free energy and only inert functional groups. This surface is not suitable for the deposition of PDA/PEI. This study utilized plasma etching treatment to break the C–H and C–F bonds on the surface of the PVDF membrane, resulting in the introduction of oxygen-containing functional groups. During the deposition process, the PDA/PEI exhibited a tendency to chemically connect to material surfaces that included oxygen-containing functional groups, such as –OH, by processes such as hydrogen bonding. During the modification procedure, the etched membrane experienced an increase in the mass of PDA/PEI deposition and the strength of interfacial bonding. As a result, the modified membrane acquired improved hydrophilicity and anti-fouling performance. In summary, this study offers useful insights for improving the surface properties of hydrophobic polymeric membranes to prevent membrane fouling.
研究领域:
材料科学
·
环境工程
✓ 已验证
产品关联
DOI
高影响因子
CHEMOSPHERE
·
2022
·
IF 8.943
Fengjie Chen,Wanchao Yu,Yarui Wang,Silong Wang,Ying Liang,Ling Wang,Yong Liang,Lixia Zhao,Yawei Wang
Photodegradation is a new approach for the removal of pentachlorophenol (PCP). Photooxidation degradation (using hydroxyl radicals) exhibits better performance to remove PCP than photoreduction degradation, but the former will lead to an increase in the production of toxic by-products such as tetrachloro-1,4-benzoquinone (TCBQ). Thus, a new strategy is required to enhance PCP photodegradation and simultaneously inhibit toxic intermediates production. Herein, TiO 2 (P25)/polydopamine (PDA)/BiOBr was synthesized and used to photodegrade PCP. Based on the relative position of the CB and VB of P25 and BiOBr, and PDA as an electron transfer mediator, a high number of holes, electrons, and superoxide anions were produced instead of hydroxyl radicals . The photocatalytic activity of P25/PDA/BiOBr exhibited the best performance among as-prepared samples, reaching a k (pcp) value of 0.4 min −1 (20 μM PCP) under UV light irradiation within 10 min. According to chemiluminescence and acute toxicity assays, relative to P25, the toxic intermediates of TCBQ and trichlorohydroxy-1,4-benzoquinone (OH-TrCBQ) generation was greatly reduced over P25/PDA/BiOBr, with a lack of toxic product generation during PCP photodegradation process. These findings provide an alternative strategy to achieve greener and more efficient organic pollutant photodegradation.
研究领域:
环境科学
·
光催化材料
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
·
2020
·Vol. 138
·期 19
·50401
·
IF 2.52
Faming Yang,Chen Xiong,Yingfu Lian,Xiaojun Wang,Zhimei Wei,Shengru Long,Gang Zhang,Jie Yang
Water-in-oil emulsions separation plays a critical role in industrial wastewater treatment. Membrane technology has attracted much interest in water-in-oil emulsions separation field for its excellent separation performance and facile processing method. However, versatile membrane with better solvent-resistance is still absent in chemical industry. In this work, oxidized polyarylene sulfide sulfone (O-PASS) membrane was severed as substrate, on which a hydrophobicity surface was built via coating of octadecyltrichlorosilane (OTS). And polydopamine (PDA) layer was employed and acted as connector between OTS and O-PASS membrane due to its abundant active hydroxyl group. The maximum water contact angle was 132.6° indicating good hydrophobicity of the membrane. Finally, the OTS/PDA/O-PASS composite membranes showed good separation performance for corrosive emulsions: the rejection and flux were 93.0% and 10.0 L/m 2 h for water-in-dichloromethane emulsions, and the rejection and flux were 92.3% and 34.6 L/m 2 h for water-in-n-hexane emulsions. The OTS/PDA/O-PASS composite membrane is a new candidate membrane for water-in-oil emulsions separation. In addition, the superior performance of the composite membrane under harsh environment conditions ensures its usefulness in resistance aggressive solvent.
研究领域:
环境工程
·
膜科学
·
废水处理
·
化学工程
✓ 已验证
产品关联
DOI
高影响因子
Materials
·
2022
·Vol. 16
·期 1
·387
·
IF 3.748
Kezhu Xu,Qunling Fang,Jing Wang,Ailing Hui,Shouhu Xuan
Due to the abuse of antibiotics, the sensitivity of patients to antibiotics is gradually reduced. This work develops a Fe3O4@SiO2@Au/PDA nanochain which shows an interesting magnetic-field-induced improvement of its photothermal antibacterial property. First, SiO2was wrapped on Fe3O4nanospheres assembled in a chain to form a Fe3O4@SiO2nanocomposite with a chain-like nanostructure. Then, the magnetic Fe3O4@SiO2@Au/PDA nanochains were prepared using in situ redox-oxidization polymerization. Under the irradiation of an 808 nm NIR laser, the temperature rise of the Fe3O4@SiO2@Au/PDA nanochain dispersion was obvious, indicating that they possessed a good photothermal effect. Originating from the Fe3O4, the Fe3O4@SiO2@Au/PDA nanochain showed a typical soft magnetic behavior. Both the NIR and magnetic field affected the antimicrobial performance of the Fe3O4@SiO2@Au/PDA nanochains.Escherichia coliandStaphylococcus aureuswere used as models to verify the antibacterial properties. The experimental results showed that the Fe3O4@SiO2@Au/PDA nanochains exhibited good antibacterial properties under photothermal conditions. After applying a magnetic field, the bactericidal effect was further significantly enhanced. The above results show that the material has a broad application prospect in inhibiting the growth of bacteria.
研究领域:
材料科学
·
生物医学工程
·
微生物学
✓ 已验证
DOI
高影响因子
POLYMER
·
2023
·
IF 4.6
Yuanlu Xu,Yi Zhu,Chunyang Song,Yinan Chen,Chengwen Song,Zaijin You,Xinfei Fan
Oil spills and oily wastewater from various industries caused severe harm to the environment and human life. Then the effective treatment of oily wastewater is extremely urgent. Superhydrophilicity/underwater superoleophobicity membranes are considered as a favorable choice for the separation of oily wastewater. In this work, inspired by mussel adhesive protein chemistry , the SiO 2 /PDA/PTFE membrane (SPP) with hydrophilic chemical components and multi-scale rough structures was prepared by the facile combination of dopamine self-polymerization and sol-gel strategy. The hydrophilic SiO 2 nanoparticles (NPs) and polydopamine layer can be co-deposited on the membrane surface through Michael addition reaction, thus avoiding the problem of coating damage during oil/water separation. Moreover, the SiO 2 /PDA layer has hydrophilic groups and micro/nano rough structure, which makes the SPP membrane possess superhydrophilic and underwater superoleophobic properties. The properties of SPP membrane facilitate the formation of a hydration layer on the membrane surface, thus minimizing direct contact with oil droplets. During the experiment of oil/water separation, SPP membrane demonstrated excellent separation ability, the permeation flux of SPP membrane was measured to be 6183 and 4389 L m −2 h −1 for oil-water mixture and oil-in-water emulsion, respectively. The oil/water separation efficiency had also reached more than 99.7%. In addition, the SPP membrane exhibited brilliant chemical stability under harsh environments. It is worth mentioning that the SPP membrane showed superior cycling and anti-fouling performance in the separation process. These excellent performances demonstrate the great potential of SPP membranes in the industrial applications.
研究领域:
材料科学
·
环境科学
·
化学工程
✓ 已验证
产品关联
DOI
高影响因子
MICROCHEMICAL JOURNAL
·
2025
·
IF 5.1
Bing zhang,Yu-lian Li,Li Wang,Haoyuan Cai
Conventional surface plasmon resonance (SPR) sensor often fails to detect low-concentration small molecules due to insufficient refractive index changes. To address this challenge, we have developed an enhanced SPR sensor utilizing Fe 3 O 4 @Au@polydopamine (PDA) core–shell magnetic nanoparticles as signal amplification tags for the detection of tebuconazole (TBZ). These nanoparticles improve sensitivity through their high refractive indices and enable TBZ enrichment from complex matrices via their magnetic properties. The sensor surface is further modified with PDA, which acts as a reducing agent for Au nanoparticle deposition, enhancing monoclonal antibody (Ab) immobilization and boosting the SPR signal. Our optimized sensor reaches a limit of detection (LOD) at 0.61 ng/mL for TBZ, with a linear response from 1-200 ng/mL, and demonstrates high selectivity and reproducibility, ideal for pesticide monitoring in food samples.
研究领域:
分析化学
·
食品科学
·
纳米技术
✓ 已验证
产品关联
DOI
高影响因子
APPLIED SURFACE SCIENCE
·
2025
·
IF 6.9
Mingyao Li,Xiaoming Wang,Ling Weng,Xue Li,Xiaorui Zhang,Houyu Wang,Li Kong
In recent years, with the breakthroughs in nanomaterial technology and manufacturing processes, the energy density of energy storage devices has been significantly improved, laying the foundation for their large-scale commercial applications. Flexible dielectric energy storage materials have received extensive attention due to their advantages such as low processing difficulty, light weight, efficient charge–discharge processes, and excellent energy storage density. However, in polymer-based nanocomposites, there are problems such as poor dispersion of nanoscale fillers and the formation of physical defects, which in turn affect the mechanical properties. To address the above issues, in this study, through surface modification technology, insulating polydopamine (PDA) was coated on the surface of barium titanate (BaTiO 3 , BT) nanoparticles to synthesize functional BT core–shell particles, which were then doped into a polyarylether nitrile (PEN) matrix with good dielectric properties to prepare PEN/BT@PDA composite dielectric materials. The influence of surface-modified BT core–shell particles on the microstructure and energy storage performance of PEN-based composite dielectric materials was investigated. The results show that the BT@PDA particles are uniformly dispersed and have good compatibility within the PEN matrix. At the same time, the dielectric properties and breakdown performance of PEN/BT@PDA have also been improved. Under an electric field of 100 Hz, the maximum dielectric constant of the PEN/BT@PDA composite dielectric material is 6.8, which is a 74 % increase compared to the original PEN film, and the dielectric loss is 0.052, showing frequency dependence. The BT@PDA particles can capture the free electrons that are free in the PEN system under an electric field, reducing the carrier mobility, thus suppressing the formation of conductive paths inside the material, regulating the overall electric field distribution of the system, and improving the insulation performance of the composite film. Therefore, the breakdown strength of the PEN/BT@PDA composite dielectric material is increased, with the maximum breakdown strength being 180.9 kV/mm, which is a 14 % increase compared to the pure PEN film. Through calculation, the maximum energy storage density of the PEN/BT@PDA composite dielectric material is 0.78 J/cm 3 , which is an 81.4 % increase compared to the pure PEN. Under an external electric field of 120 kV/mm, the charge–discharge efficiency of the PEN/BT@PDA composite dielectric material can reach 69 %, demonstrating that BT@PDA can enhance the energy storage performance of PEN[30].
研究领域:
材料科学
·
纳米技术
·
电气工程
·
高分子科学
✓ 已验证
产品关联
DOI
高影响因子
APPLIED SURFACE SCIENCE
·
2024
·
IF 6.3
Shun Hu,Hua-yun Du,Hao Huang,Ying-hui Wei,Li-feng Hou,Qian Wang,Huan Wei,Xiao-da Liu,Yan Zhou,Hong-wei He
Micro arc oxidation-Polydopamine (MAO-PDA) composite coating is a functional corrosion resistant coating formed on the surface of magnesium alloy by combining MAO to form a porous ceramic layer and the spontaneous oxidation polymerization characteristics of PDA. The MAO-PDA coating is environmentally friendly and modifiable, providing a basic film layer for achieving self-warning, self-healing, conductivity and other modification functions, which has attracted widespread attention. A new type of MAO-PDA composite coating with good corrosion resistance was deposited on the surface of magnesium alloy by photocatalysis, which expanded the application range of magnesium alloy MAO surface treatment. Surface morphology, coating adhesion and corrosion resistance of the composite coating are characterized. Combined with Density functional theory (DFT) calculation, the possible mechanism is explored. The results indicate that the MAO layer containing Mg 2 TiO 4 exhibits fewer pores and can better deposit PDA under ultraviolet (UV) light conditions, forming a magnesium alloy MAO-PDA composite coating with good corrosion resistance and modification friendliness. Band structure calculations confirm the photocatalytic effect of Mg 2 TiO 4 under UV irradiation. As a result of the photocatalytic effect, reactive oxygen species (ROS) were generated in the pores and on the surface of the MAO sample, thus accelerating the local deposition of PDA.
研究领域:
材料科学
·
表面工程
·
腐蚀与防护
✓ 已验证
产品关联
DOI
高影响因子
Frontiers of Environmental Science & Engineering
·
2022
·Vol. 16
·期 11
·1-12
·
IF 6.048
Li Qingqing,Lv Chao,Xia Xiangwei,Peng Chao,Yang Yan,Guo Feng,Zhang Jianfeng
High-performance adsorbents have been well-studied for the removal of organic dye pollutants to promote environment remediation. In this study, an Ag nanoparticle-functionalized Fe 3 O 4 -PDA nanocomposite adsorbent (PDA-Fe 3 O 4 -Ag) was synthesized, and the adsorption/separation performance of commonly used cationic and anionic organic dyes by the PDA-Fe 3 O 4 -Ag adsorbent were assessed. Overall, PDA-Fe 3 O 4 -Ag exhibited a significantly higher adsorption capacity for cationic dyes compared to anionic dyes, the highest of which was more than 110.0 mg/g (methylene blue (MB)), which was much higher than not only the adsorption capacities of the anionic dyes in this study but also other dye adsorption capacities reported in the literature. The dye adsorption kinetics data fitted well to both the pseudo second-order kinetics model and the Langmuir isotherm model, suggesting a monolayer-chemisorption-dominated adsorption mode. Thermodynamics analysis indicated that the adsorption process was both endothermic and spontaneous. Furthermore, the PDA-Fe 3 O 4 -Ag adsorbent achieved high photodegradation removal rates of the dyes, especially neutral red (NR) and methyl orange (MO), which were 91.2% and 87.5%, respectively. With the addition of PDA-Fe 3 O 4 -Ag, the degradation rate constants of NR and MO increased from 0.08 × 10 −2 and 0 min −1 to 2.11 × 10 −2 and 1.73 × 10 −2 min −1 , respectively. The high adsorption and photocatalytic degradation performance of the PDA-Fe 3 O 4 -Ag adsorbent make it an excellent candidate for removing cationic and anionic dyes from the industrial effluents.
研究领域:
环境科学
·
材料科学
✓ 已验证
DOI
高影响因子
OPTICS AND LASER TECHNOLOGY
·
2025
·
IF 5
Fengtong Zhu,Kun Liu,Jianying Jing,Lu Xiao,Xiaohan Zhan,Jinchang Liu,Yiyang Xiong,Junfeng Jiang,Tianhua Xu,Shuang Wang,Tiegen Liu
A SnS 2 -polydopamine (PDA) enhanced nearly guided-wave surface plasmon resonance (NGW-SPR) refractive index (RI) probe with high sensitivity and high-resolution has been proposed. For the first time, we systematically analyze the high-resolution demodulation methods for the optical fiber SPR sensor in terms of the wavelength resolution of the sensing system, rather than the spectrometer parameter. The sensor resolution is improved by increasing the sensor sensitivity and reducing the standard deviation of the resonance wavelength monitoring values. Taking advantage of the popular thermoelectric material SnS 2 with high carrier mobility and PDA with mussel adhesion properties, the composite material SnS 2 -PDA can effectively improve the sensitivity of the RI probe. To ensure accurate and high-resolution extraction of the SPR resonance wavelength, a wavelet packet denoising demodulation algorithm based on the self-calibrating polynomial fitting is developed. Experimental results demonstrate that the average sensitivity of the proposed RI probe achieves up to 3191.61 nm/RIU within the range of 1.3330 ∼ 1.3560 RIU. The probe offers a resolution of 3.47 × 10 −5 RIU, which is 1 ∼ 2 orders of magnitude higher than previously reported RI sensors. The proposed high-resolution NGW-SPR RI probe provides a new idea for the detection of small molecules interaction analysis with low limit of detection (LOD) in biochemistry.
研究领域:
光学传感器
·
材料科学
·
生物化学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
·
2018
·
IF 3.235
Fang Peng,Meilin Chu,Jiajia Sun,Yuhong Liu,Qicheng Zhang,Yajun Chen,Fenghe Wang,Wenbo Zhao
The electrochemical immunosensor was fabricated by immobilizing alpha-fetoprotein (AFP) antigen onto the magnetic glassy carbon electrode (MGCE) that modified by Fe 3 O 4 @polystyrene (PS)/polydopamine (PDA)-Au nanotubes . The aim of this study was to develop a new route to prepare Fe 3 O 4 @PS/PDA-Au nanotubes with well dispersed Au nanoparticles (AuNPs). The immune detection platform showed good analytical performance for determination AFP in a linear range of 0.01–100 ng/mL with a correlation coefficient of 0.9970 under optimal conditions. The detection limit was calculated to 0.0088 ng/mL (S/N = 3). In addition, the good detection results of AFP in human serum were obtained by the immunosensor. The use of composite nanotubes to build advanced biosensing interface will bring more possibilities for future biomedical detection.
研究领域:
生物医学工程
·
分析化学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）