CATALYSIS LETTERS
·
2023
·Vol. 153
·期 12
·3837-3845
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IF 2.8
Wang Xue,Duan Zuqin,Wei Richu,Lei Qian,Chen Honglin
Trioxane (TOX), which is usually produced from formaldehyde catalyzed by acid-catalysts, is an important polymerizing monomer to produce high-performance plastics polyoxymethylene polymers (POMs). In order to reduce the separation cost and increase the catalytic activity, hierarchical Beta zeolites with different pore size were synthesized by PDDA and used for TOX produce from formaldehyde in this work. Hierarchical Beta zeolites’ average pore size increased with the increasing of PDDAs’ molecular weight. Compare to conventional Beta zeolite, it exhibited a higher catalytic performance with 95.13% selectivity and 2118 g/kg/h space–time yield of TOX due to its excellent diffusion performance from extra mesopore. The HCHO conversion and space–time yield of TOX increase first and then decrease with the pore size increasing. Further research showed that the decrease of catalytic activity is mainly due to the increase of extra-framework Al percent. This work illustrates the influence of both pore size and extra-framework Al content in hierarchical Beta zeolites for TOX produce from formaldehyde reaction. Graphical Abstract
研究领域:
化学工程
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材料科学
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催化
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DOI
高影响因子
DIAMOND AND RELATED MATERIALS
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2025
·
IF 5.1
Kang Ren,Juanqin Xue,Bin Liu,Heping Wang,Yongqiang Tian,Xue Han,Changbin Tang
Despite Ti 3 C 2 T x- based filler has gained enormous application in improving the anti-corrosion of epoxy coatings, it is still insufficient to achieve the quality standard to face long-term service conditions. In this work, a composite coating integrated with Ti 3 C 2 T x and epoxy resin was prepared, which was fabricated by functionalizing Ti 3 C 2 T x through a strong cationic poly (diallyl dimethyl ammonium) chloride (PDDA) electrostatic adsorption and ionic liquids (ILs) to improve the chemical stability, and then the functionalized Ti 3 C 2 T x was controlled to parallelly distributed in epoxy under the external electric field. Results showed that Ti 3 C 2 T x nanosheets fillers in the prepared epoxy coating exhibit a flat arrangement for resisting infiltration. After immersion in 3.5 wt% NaCl solution for 28 days, the low-frequency impedance modulus of the prepared PDDA-ILs@Ti 3 C 2 T x /EP coating was about 1–2 orders of magnitude compared to that of epoxy coating and was maintained above 10 8 Ω. cm 2 . Integrating the triple effect of the interfacial interaction, directional-aligned barrier effect and intelligent effect formed by ILs, it can provide new idea for developing MXene-based smart coating for the corrosion protection of oil and gas field pipelines steel.
研究领域:
材料科学
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腐蚀防护
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纳米复合涂层
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表面工程
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产品关联
DOI
高影响因子
ACS Applied Materials & Interfaces
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2021
·
IF 9.229
Senyao Wang,Baoshan He,Ying Liang,Huali Jin,Min Wei,Wenjie Ren,Zhiguang Suo,Jinshui Wang
Herein, a hierarchically porous Zr-MOF-labeled electrochemical aptasensor based on the composite of PtPd@Ni-Co hollow nanoboxes (PtPd@Ni-Co HNBs) and poly (diallyldimethylammonium chloride)-functionalized graphene (PDDA-Gr) was developed for ultrasensitive detection of chloramphenicol (CAP). PtPd@Ni-Co HNBs have excellent conductivity and provide binding sites for aptamers; the functionalized PDDA-Gr improves its dispersibility and conductivity as a substrate material, which can be successfully used to increase the electrode surface area and support more PtPd@Ni-CoHNBs. Besides, hierarchically porous Zr-MOFs (HP-UiO-66) were utilized as signal probes and showed a stronger load capacity for signal molecules than conventional UiO-66. In the presence of CAP, two ingeniously designed Exo III-assisted cyclic amplification strategies further improved the sensitivity of the aptasensor: CAP causes cycle I to release a large amount of trigger DNA (Tr DNA), and then, Tr DNA initiated cycle II, which causes the exposed capture DNA to further bind the signal probes. With these advantages, the constructed aptasensors performed with satisfactory sensitivity in a wide linear range (10 fM–10 nM) and a detection limit of 0.985 fM. Several signal amplification strategies adopted in this study have effectively improved the performance of the sensor, providing a new avenue for the development of ultrasensitive sensors in the food analysis field.
研究领域:
分析化学
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食品科学
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生物传感技术
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DOI
PubMed
高影响因子
ELECTROCHIMICA ACTA
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2013
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IF 3.777
Yonghai Song,Hongyu Liu,Yu Wang,Li Wang
Glucose oxidase (GOD) and cytochrome c (Cyt c ) were co-entrapped in the poly(diallyldimethylammonium chloride)–graphene nanosheets–gold nanoparticles (PDDA–Gp–AuNPs) hybrid nanocomposites modified glassy carbon electrode to prepare a novel bi-protein bio-interphase. Electron transfer and electrocatalysis of the bi-protein bio-interphase were investigated in detail. The results showed that the PDDA–Gp–AuNPs nanocomposites accelerated the electron transfer between proteins and electrode. The bi-protein exhibited effective direct electron transfer (DET) reaction with an apparent rate constant ( k s ) of 2.36 s −1 . The optimal molar ratio and total amount of Cyt c and GOD in the bio-interphase for DET of GOD was estimated to be about 3:1 and 1.40 nmol, respectively. The bi-protein bio-interphase could be used to detect glucose based on the consumption of O 2 with the oxidation of glucose catalyzed by GOD. The resulted biosensor exhibits wide linear range from 2.0 to 18.0 mM. Thus, this study not only successfully achieved DET of GOD, but also constructed a novel biosensor for glucose detection.
研究领域:
生物化学
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电化学
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纳米技术
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分析化学
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产品关联
DOI
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
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2021
·
IF 7.46
Rongyang Liu,Li Jiang,Zizhen Yu,Xufeng Jing,Xiu Liang,Dan Wang,Bo Yang,Chengxing Lu,Wei Zhou,Shangzhong Jin
Recent years, two-dimensional transition metal carbonitrides, MXene, have emerged as SERS substrates due to their unique optical and electrical properties. In order to combine the advantages of metal nanoparticles and MXene for SERS substrates, this paper prepared an MXene (Ti 3 C 2 T x ) -Ag nanoparticles (NPs) hybrid biosensor through in-situ electrostatic self-assembly method, in which the citrate-coated Ag NPs are loaded on the negatively surface of Ti 3 C 2 T x flakes through positively charged PDDA polymer. The characterizations show that a large number of Ag NPs uniformly adsorb on both side of Ti 3 C 2 T x nanosheets. The prepared platform exhibits excellent SERS performance, long-term stability and good uniformity by detecting 4-MBA molecules. The electromagnetic field distribution was simulated to theoretically show the Raman enhancement mechanism of this platform. In order to explore the possible application of the sensor in clinical diagnosis and monitoring of biological environment, the platform was used for biomolecule detection. The detection limit of adenine molecules can be as low as 10 −8 M. For dopamine molecules with concentration ranging from 5 × 10 -6 M to 5 × 10 −8 M, the SERS results show a linear relationship between peak intensity and concentration of dopamine molecules. The biosensor was applied for serum detection. The results suggest that MXene-PDDA-Ag NPs hybrid platform could be used as a sensitive and uniform biosensor for label-free quantitative detection of bio-molecular based on SERS method, which could be applied in the field of biotechnology.
研究领域:
材料科学
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生物技术
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分析化学
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DOI
高影响因子
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
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2019
·Vol. 412
·期 3
·669-680
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IF 3.286
Pang Xi,Li Fusen,Huang Songqing,Yang Zeqi,Mo Qian,Huang Li,Xu Wanpeng,Chen Limin,Li Xinchun
A layer-by-layer self-assembled nitrogen-doped graphene/PDDA/gold nanoparticle (NDG/PDDA/GNP) composite was described. Citrate-stabilizing gold nanoparticle colloids (GNPs) were electrostatically adsorbed onto NDG nanosheets using a cationic polyelectrolyte, polydiallyldimethylammonium (PDDA), as the linker, thereby creating a high-performance electrochemical interface. The morphology and chemical composition were characterized by scanning electron microscopy, transmission electron microscopy, X-ray photoelectron spectroscopy, ultraviolet-visible spectroscopy, infrared spectroscopy, and Raman spectroscopy. Analytical application was manifested by electrochemical sensing of uric acid (UA), a biomarker involved with a variety of clinical diseases. The prepared nanocomposite exhibited noticeable electroactivity to uric acid oxidation and can give effective peak separation with ascorbic acid and dopamine. Additionally, the nanocomposite practically averted from other potentially interferents including glucose, urea, and serotonin, thus allowing selective voltammetric detection of UA in the biological matrix. Under the optimal condition, peak currents measured by differential pulse voltammetry were proportional to UA concentrations in the range of 0.5~100 μM ( R 2 = 0.998), with the detection limit of 53 nM. The NDG/PDDA/GNP nanocomposite as presented herein holds potential for aiding the diagnosis of UA-associated diseases and should be a new opportunity for biochemical analysis and biosensing applications.
Graphical abstract
研究领域:
纳米技术
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电化学
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生物传感器
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分析化学
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产品关联
DOI
PubMed
高影响因子
TALANTA
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2018
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IF 4.244
Jiantong Qiao,Yulong Zhang,Sheng Lei,Zi Liu,Gaiping Li,Baoxian Ye
The nanocomposite of ruthenium oxide (RuO 2 ) loaded on Poly-(dimethyldiallylammonium chloride) (PDDA) functionalized reduced graphene oxide (RuO 2 -PDDA-rGO) was synthesized based on a one-step method. Based on the RuO 2 -PDDA-rGO modified glassy carbon electrode (GCE), a new electrochemical sensor (RuO 2 -PDDA-rGO/GCE) was fabricated and used in detection of baicalein for the first time. Compared with other reported electrochemical sensors for the detection of baicalein, the prepared RuO 2 -PDDA-rGO/GCE had a wider linear range (2–400 nM) and lower detection limit (0.6 nM, S/N = 3). The other advantages were the excellent repeatability of proposed method and good stability of prepared sensor.
研究领域:
分析化学
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纳米技术
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电化学
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产品关联
DOI
PubMed
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2018
·
IF 5.667
Shuo Li,Yinghao Duan,Sheng Lei,Jiantong Qiao,Gaiping Li,Baoxian Ye
In this work, a brand new nanocomplex (denoted as [email protected] ) is elaborately designed and successfully synthesized meaning the in-situ assembly of porous-morphology Zn-based MOFs (MOF-5) onto the as-prepared PDDA-rGO-Ni (PGN for short) nanocomposites. When this nanocomplex contributes to construct the electrochemical sensor ( [email protected] /GCE), it presents a highly-sensitive response towards echinacoside, and the first measurement for echinacoside by electrochemistry accordingly evolves forward. The crystallization processes are investigated by FT-IR instrument and XRD analysis, as well as micro-morphology of modified materials is visible upon SEM and TEM. Adorably, a novel ratiometric sensor was progressively fabricated by encapsulating methylene blue (MB) molecules into cubic MOF-5 framewoks (MB encased [email protected] /GCE), and apart from assisting in establishing the analysis method with extreme accuracy and favorable practicality, it dose devote a wider linear scale and a lower detection limit than that [email protected] /GCE has given out. Drawn from the developed calibration curve using differential pulse voltammetry (DPV) technique, the peak intensity ratio (I Ech /I MB ) varies linearly with increased echinacoside concentration in the range of 3.0 × 10 −8 – 1.0 × 10 −6 mol L −1 with limit of detection (LOD) reaching 1.0 × 10 −8 mol L −1 (S/N = 3). Additionally, the proposed assay method has been employed to detect echinacoside in real sample sliced cistanche with satisfactory results.
研究领域:
分析化学
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电化学
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纳米材料
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药物分析
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DOI
高影响因子
Environmental Chemistry and Ecotoxicology
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2025
·
IF 8.2
Huizi Zheng,Zhipeng Zhang,Guanlan Wu,Haoming Sun,Xiaolin Zhu,Jiao Qu,How Yong Ng
Nanoplastics and bisphenols (including bisphenol A and its alternatives) are emerging co-contaminants in aquatic ecosystems, yet their combined toxicological effects remain poorly understood. To address this gap, we developed a novel electrochemical biosensor using HepG2 cells and a nanocomposite of hydroxylated multi-walled carbon nanotubes, poly(diallyldimethylammonium chloride), and boron-doped graphene quantum dots (MWCNT-OH/PDDA/B-GQDs). This unique composite design, verified by density functional theory (DFT) calculations, revealed strong adsorption energies for cellular electroactive substances (xanthine: −1.12 eV; guanine: −1.56 eV), confirming the sensor's superior detection capability. The biosensor was used to assess the cytotoxicity of polystyrene nanoplastics (PS 25 nm ) and five bisphenols individually; their mixture exhibited an additive combined effect. Beyond rapid toxicity screening, we further conducted comprehensive mechanistic investigations through oxidative stress analysis, apoptosis assessment, and transcriptome sequencing. Results indicated that exposure to PS 25 nm and bisphenols, either individually or in combination, induced oxidative stress, as evidenced by decreased glutathione (GSH) levels and reduced superoxide dismutase (SOD) activity. Transcriptome analysis revealed substantial enrichment of differentially expressed genes in the pathways related to protein synthesis, oxidative stress response, and liver disease. This study not only establishes a rapid and sensitive approach for evaluating the toxicity of nanoplastics and bisphenols in aquatic environments but also provides a comprehensive understanding of the underlying mechanisms through integrated multi-level analysis, thereby providing essential mechanistic data to support their comprehensive biosafety assessment and regulatory management.
研究领域:
环境毒理学
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分析化学
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纳米材料
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环境科学
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生物电化学
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分子生物学
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产品关联
DOI
高影响因子
Surfaces and Interfaces
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2021
·
IF 4.837
Zhuanggang Yang,Gaowen Chen,Yiyan Huang,Qianmin Liang,Huifang Shen
In recent years, structural colored coatings have become a hot spot for research because of the advantages of colorfast and eco-friendly. Nevertheless, it is still a great challenge to balance the conflict among color, luminosity, saturation and angle dependence of the coatings. In this work, we used electrophoretic deposition (EPD) technique with variable voltage assembly to deposit polydopamine coated polystyrene nanoparticles ( [email protected] NPs) with poly (dimethyldiallylammonium chloride) (PDDA). By varying the voltage of the EPD duration, structural colored coatings with hierarchical structure were prepared, which exhibited bright colors with low angle dependence. More importantly, the films could be coated on curved surfaces and other complicated shapes, which would have many practical applications in the future.
研究领域:
材料科学
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纳米技术
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涂层技术
·
表面工程
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产品关联
DOI
高影响因子
MICROCHIMICA ACTA
·
2023
·Vol. 190
·期 4
·1-8
·
IF 5.7
Wu Ning-Ning,Chen Lin-Ge,Xiao Min-Zhi,Yuan Rong-Yao,Wang Hai-Bo
A fluorescent method is described for trypsin determination through the strong electrostatic interactions between cationic polyelectrolytes and single-stranded DNA (ssDNA) templated Au nanoclusters (AuNCs). The ssDNA-AuNCs display improved fluorescence emission with excitation/emission maxima at 280/475 nm after being incorporated with poly(diallyldimethylammonium chloride) (PDDA). Fluorescent enhancement is mainly attributed to the electrostatic interactions occurring between PDDA and ssDNA templates. This can make the conformation of the ssDNA templates to change. Thus, it offers a better microenvironment for stabilizing and protecting ssDNA-AuNCs, and results in fluorescence emission enhancement. By using protamine as a model, the method is employed for the determination of trypsin. The assay enables trypsin to be determined with good sensitivity and a linear response ranging from 5 ng⋅mL −1 to 60 ng⋅mL −1 with a 1.5 ng⋅mL −1 limit of detection. It is also extended to determine the trypsin contents in human’s serum samples with recoveries between 98.7% and 103.5% with relative standard deviations (RSDs) between 3.5% and 4.8%. Graphical abstract A novel fluorescent strategy has been developed for of trypsin determination by using protamine mediated fluorescent enhancement of DNA templated Au nanoclusters.
研究领域:
分析化学
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生物化学
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纳米技术
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产品关联
DOI
PubMed
高影响因子
Nature Communications
·
2022
·Vol. 13
·期 1
·1-15
·
IF 17.694
Zhang Yiyi,Tian Sidan,Huang Liping,Li Yanan,Lu Yuan,Li Hongyu,Chen Guiping,Meng Fanling,Liu Gang L.,Yang Xiangliang,Tu Jiasheng,Sun Chunmeng,Luo Liang
Combining immune checkpoint blockade (ICB) therapy with photodynamic therapy (PDT) holds great potential in treating immunologically “cold” tumors, but photo-generated reactive oxygen species (ROS) can inevitably damage co-administered ICB antibodies, hence hampering the therapeutic outcome. Here we create a ROS-responsive hydrogel to realize the sustained co-delivery of photosensitizers and ICB antibodies. During PDT, the hydrogel skeleton poly(deca-4,6-diynedioic acid) (PDDA) protects ICB antibodies by scavenging the harmful ROS, and at the same time, triggers the gradual degradation of the hydrogel to release the drugs in a controlled manner. More interestingly, we can visualize the ROS-responsive hydrogel degradation by Raman imaging, given the ultrastrong and degradation-correlative Raman signal of PDDA in the cellular silent window. A single administration of the hydrogel not only completely inhibits the long-term postoperative recurrence and metastasis of 4T1-tumor-bearing mice, but also effectively restrains the growth of re-challenged tumors. The PDDA-based ROS-responsive hydrogel herein paves a promising way for the durable synergy of PDT and ICB therapy.
研究领域:
癌症治疗
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材料科学
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生物医学工程
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免疫学
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药学
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产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）