INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2026
·
IF 8.7
Cuibin Zhu,Ruitong Qin,Xiaoyu Wang,Zhiming Jiang
The cooperation of ATMP and Tris imparted cotton fabric with multifunction. • ATMP as a cross-linker offered a common strategy to prepare flame-retardant multifunctional cellulosic fabric. • Tris as N-halamine precursor and pH buffer simultaneously enhanced antibacterial and mechanical properties. Cellulose fabric, as a popular textile material, demands multifunctional modification to broaden its application landscape. Although phosphorylation is an effective approach to endow flame retardancy, it often severely impairs the mechanical properties of cellulose fabric. To address this challenge, a buffering strategy was developed to alleviate this problem in this study while concurrently achieving antibacterial performance. A multifunctional flame-retardant and antibacterial cotton fabric was prepared via a one-pot process using triphosphate acid ATMP as cross-linker, and Tris as both a buffer and an N-halamine precursor. ATMP/Tris-modified fabric exhibited excellent flame retardancy with 31.7% of LOI value and self-extinguishing performance at a low weight gain. Simultaneously, the formation of N-halamine structures conferred superior antibacterial efficacy against E. coli and S. aureus , resulting in complete inactivation within a few minutes without any leaching. The multifunctional fabric exhibited notable washing durability, retaining 83% of its original LOI value after repeated laundering. Notably, in addition to maintaining good flexibility, the incorporation of Tris significantly improved the whiteness, air permeability, and breaking force of cellulose fabric compared to the ATMP-modified counterpart. Therefore, this work offers a simple strategy to enhance the comprehensive properties of flame-retardant multifunctional cellulose fabric. Download: Download high-res image (152KB) Download: Download full-size image
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高影响因子
Toxics
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2025
·Vol. 13
·期 4
·285
·
IF 4.1
Yonggang Zhao,Mo Peng,Honglei Liu,Xiaoyu Zhang,Dan Fu
Tris(2-chloroethyl) phosphate (TCEP) is a representative chlorinated organophosphate flame retardant (OPFR) that demonstrates greater persistence than other non-halogenated alkyl or aryl OPFRs. Although TCEP has been shown to accumulate significantly in the environment and contribute to testicular toxicity and spermatogenic dysfunction, the precise underlying factors and mechanisms of action remain unclear. Herein, male ICR mice were gavaged with corn oil, 50 mg/kg body weight (bw) TCEP, or 100 mg/kg bw TCEP from postnatal day (PND) 22 to PND 35. TCEP exposure resulted in the disruption of blood-testis barrier (BTB) integrity and in abnormal testicular development. Considering that Sertoli cells constitute the primary target of toxicants and that TCEP induces oxidative stress in the testis and other organs, we focused on ferroptosis in Sertoli cells. Our findings revealed a significant increase in ferroptosis in the testes and Sertoli cells following TCEP exposure, and we observed functional restoration of Sertoli cell junctions upon treatment with the ferroptosis inhibitor ferrostatin-1. Furthermore, ferritin heavy chain 1 (FTH1) was markedly reduced in TCEP-exposed testes and Sertoli cells. Since nuclear receptor coactivator 4 (NCOA4)-mediated ferritinophagy is essential for the degradation of FTH1, we assessed ferritinophagic activity and found significant upregulation of NCOA4, ATG5, ATG7, and LC3B II/I in TCEP-exposed testes and Sertoli cells. These results strongly suggest that TCEP triggers Sertoli cell ferroptosis by activating ferritinophagy that leads to reduced expression of BTB-associated proteins, ultimately causing BTB disruption and testicular developmental toxicity.
研究领域:
生殖毒理学
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环境健康科学
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PubMed
高影响因子
ANALYST
·
2025
·
IF 3.3
Nan Shi,Shuyu Li,Laidi Xu,Junyao Li,Wenrong Cai,Datong Wu,Yong Kong
Mesoporous hollow polymer microspheres (M-HPMs) are modified with cellulose tris(3,5-dimethylphenylcarbamate) (CDMPC), and the obtained chiral hollow polymer microspheres (C-HPMs) are utilized for the spectroscopic chiral discrimination of naproxen (NPX) isomers. Thanks to the intrinsic chirality of CDMPC and the mesoporous structure of M-HPMs, the NPX isomers exhibit significant differences in their absorbances on the ultraviolet (UV) spectra after being adsorbed by the C-HPMs. Several parameters including adsorption time, mass ratio of CDMPC to M-HPMs, and NPX concentration are optimized to achieve the highest discrimination efficiency for the NPX isomers. Compared with the M-HPMs modified with sodium carboxymethyl cellulose and the hollow polymer microspheres (HPMs) directly modified with CDMPC, the C-HPMs show higher discrimination efficiency for the NPX isomers.
研究领域:
分析化学
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药学
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PubMed
高影响因子
MOLECULES
·
2025
·Vol. 30
·期 12
·2573
·
IF 4.6
Jinliang Lin,Rongying Liao,Li Li,Shuli Yao,Shengkai Li,Yun Zheng,Fei Fei
Photocatalytic CO2conversion is one of the ideal approaches to address both topics of solar energy shortage and carbon neutrality. Cobalt(II) centers coordinated with bipyridines have been designed and evaluated as catalysts for CO2conversion under light irradiation. Herein, we report a series of pyridine-based cobalt complexes with alkyl substituents as molecular photocatalysts, aiming to elucidate the effects of alkyl type and substitution position on catalytic performance through spectroscopic and electrochemical measurements. The substitution of the hydrogen at 4,4′-positions on the bipyridine ring with a methyl group, a tert-butyl group, and a nonyl group led to a decrease in the conversion rate of CO2by 13.2%, 29.6%, and 98%, respectively. The methyl substituents at the 5, 5′-positions of the bipyridine ring resulted in a 71.1% decrease in the CO2conversion rate. The usage of either 6, 6′-Me2-2,2′-bipy, 2,4-bipy, or 3,3′-bipy resulted in no detectable activity for CO2conversion in the current system. Both photo- and electrochemical analyses have been employed to reveal the relationship between changing ligands and photocatalytic performance on the molecular scale. These results demonstrate that bulky ligands significantly hinder CO2reduction by cobalt complexes due to steric interference with coordination and active-site accessibility. This study demonstrates that the substituent effect of ligands on photocatalytic reactions for CO2conversion provides valuable insight into a deeper understanding of molecular catalysis.
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高影响因子
ChemElectroChem
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2020
·Vol. 7
·期 5
·1207-1212
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IF 4.154
Abubakar Abdussalam,Yiran Guan,Guobao Xu
Graphical Simplify to amplify : Isatin is investigated as a new efficient co-reactant for Ru(bpy) 3 2+ electrochemiluminescence (ECL), and the ECL response of the Ru(bpy) 3 2+ /isatin system in borate buffer solution is about 12 times more intense than in phosphate buffer of the same pH, enabling sensitive ECL detection of isatin. Isatin is an endogenous indole derivative that has been reported to possess various pharmacological and therapeutic activities of clinical importance. To date, isatin has been detected mainly by mass spectrometry. Here, we report for the first time the intense anodic electrochemiluminescence (ECL) of tris(2,2′-bipyridyl)ruthenium(II) with isatin as an efficient co-reactant. Interestingly, the ECL response of the Ru(bpy) 3 2+ /isatin system in borate buffer solution is about 12 times more intense than in phosphate buffer of the same pH; and approximately 114 times greater than the ECL intensity of the luminophore. Under the optimal conditions, the ECL of Ru(bpy) 3 2+ increases linearly with the concentration of the isatin in the range of 1.0 μM to 1.0 mM (R 2 =0.998) with a limit of detection (LOD) of 0.28 μM (3σ/m). Moreover, the method has been successfully applied to the detection of isatin in human urine. The developed method has shown excellent recoveries in the range of 99.7–101.3 %. The anodic ECL assay reported in this work is superior in terms of linear range and selectivity than the previously reported methods and can be applied for the detection of isatin in real samples.
研究领域:
分析化学
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生物医学
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高影响因子
ChemSusChem
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2020
·Vol. 13
·期 15
·3844-3854
·
IF 7.962
Yaokang Lv,Xing Yang,Weishi Du,Peihua Ma,Hu Wang,Antoine Bonnefont,Dominic S. Wright,Laurent Ruhlmann,Cheng Zhang
Graphical Caught on film : Tris[4-(3,4-ethylenedioxythiophene)phenyl]amine was obtained by a green synthetic route and its solution-processable nanoporous polymer was used to fabricate an efficient all-solid-state electrochromic supercapacitor. A new green synthetic route to tris[4-(3,4-ethylenedioxythiophene)phenyl]amine (TEPA) monomer has been developed and the molecular structure of TEPA has been determined by using single-crystal XRD. Solution-processable nanoporous poly{tris[4-(3,4-ethylenedioxythiophene)phenyl]amine} (PTEPA) is prepared by a chemical oxidative polymerization in a microemulsion. Based on the distorted structure of TEPA in the solid state, it is proposed that dendritic PTEPA has a distorted 3 D conformation with multiple twisted channels and pores that are narrowed and blocked by bifurcation and distortion of PTEPA, which is consistent with the observed hierarchical pore structure. As a cathode material, PTEPA exhibits a discharge capacity of 89.5 mAh g −1 in the initial cycle with a highly sloping two-stage discharge curve and relatively stable cycling performance. Beyond its excellent energy storage properties, PTEPA also shows relatively good electrochromic performance. Furthermore, an efficient all-solid-state electrochromic supercapacitor (ECSC) with good electrochromic performance and high energy storage capacity (13.3 mF cm −2 ) is assembled from PTEPA and nanoporous graphene films. During charge–discharge processes, the color of the ECSC changes between yellow-green and steel blue. Thus, the energy storage level of the ECSC can be monitored by the corresponding color changes. The fabricated ECSC may have practical applications, for example, in self-powered electrochromic smart windows.
研究领域:
材料科学
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能源存储
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电化学
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PubMed
高影响因子
ACS Sustainable Chemistry & Engineering
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2021
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IF 8.198
Yue Zou,Ang Fu,Jing Zhang,Tianpeng Jiao,Yong Yang,Jianming Zheng
To achieve higher energy density, LiCoO2 (LCO) is being developed for high-voltage operation at raised charge cutoff voltages up to 4.6 V vs Li/Li+, which however is beyond the electrochemical stability window of carbonate-based electrolytes. In this work, a novel electrolyte additive 2,4,6-tris(4-fluorophenyl)boroxin (TFPB) is proposed for enhancing the interfacial stability of LCO. Thanks to the TFPB additive, the LCO cathode exhibits substantially improved capacity retention of 84.6% after 200 cycles at 1C at a high charge cutoff of 4.6 V, surpassing the 63.2% attained in the baseline electrolyte. The improved performance could be rationalized by the fact that TFPB additive is preferentially oxidized to build a uniform and protective B–O bond-containing cathode–electrolyte interphase, contributing to the reduced parasitic side reactions, inhibited surface structural transformation, and better-maintained interfacial lithium-ion diffusion kinetics.
研究领域:
材料科学
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电化学
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高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
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2014
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IF 3.84
Zengchen Liu,Yanxia Li,Yongjie Ding,Zhengyin Yang,Baodui Wang,Yong Li,Tianrong Li,Wen Luo,Wenping Zhu,Jianping Xie,Chunjie Wang
In the paper, a highly selective aluminum ion fluorescent probe based on naphthalene derivate has been synthesized and characterized systemically. The probe molecule for aluminum ion exhibits excellent water solubility, and it shows strong blue fluorescence under ultraviolet light, which is attributed to the Photoinduced Electron Transfer (PET) process. In addition, the large association constant between probe and aluminum ion is 1.19 × 10 8 M −1 , which is obtained by fluorescent measurement. Moreover, the binding site of L with Al 3+ is determined by 1 HNMR titration experiment.
研究领域:
分析化学
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传感器与仪器
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荧光光谱学
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环境监测
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无机化学
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高影响因子
SCIENCE OF THE TOTAL ENVIRONMENT
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2020
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IF 6.551
Min Xia,Xuedong Wang,Jiaqi Xu,Qiuhui Qian,Ming Gao,Huili Wang
The organophosphate flame retardant, tris (1-chloro-2-propyl) phosphate (TCPP), is ubiquitous in environmental matrices; however, there is a paucity of information concerning its systemic toxicity. Herein, we investigated the effects of TCPP exposure on zebrafish neurodevelopment and swimming behavior to elucidate the underlying molecular mechanisms of neurotoxicity. Under TCPP gradient concentration exposure, the hatching rates were declined by up to 33.3% in 72 hpf, and the malformation rates increased from 15% to 50%. Meanwhile, TCPP led to abnormal behaviors including decreased locomotive activity in the dark and slow/insensitive responses to sound and light stimulation of larvae. TCPP caused excessive apoptosis and ROS accumulation in early embryonic development, with hair cell defects and structural deformity of neuromast. Abnormal expression of neurodevelopment ( pax6a , nova1 , sox11b , syn2a , foxo3a and robo2 ) and apoptosis-related genes ( baxa , bcl2a and casp8 ) revealed molecular mechanisms regarding abnormal behavioral and phenotypic symptoms. Chronic TCPP exposure led to anxiety-like behavior and excessive panic, lower capacity for discrimination and risk avoidance, and conditioned place preference in adults. Social interaction tests demonstrated that long-term TCPP stress resulted in unsociable, eccentric, lonely and silent behaviors in adults. Zebrafish memory and cognitive function were severely reduced as concluded from T-maze tests. Potential mechanisms triggering behavioral abnormality were attributed to histopathological injury of diencephalon, abnormal changes in nerve-related genes at transcription and expression levels, and inhibited activity of AChE by TCPP stress. These findings provide an important reference for risk assessment and early warning to TCPP exposure, and offer insights for prevention/mitigation of pollutant-induced nervous system diseases.
研究领域:
毒理学
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神经科学
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环境科学
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发育生物学
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PubMed
高影响因子
CHEMOSPHERE
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2020
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IF 5.778
Hang Liu,Hua Yin,Shaoyu Tang,Hui Peng,Xiaolong Yu,Guining Lu,Zhi Dang
In this work, the prepared mesoporous TiO 2 was employed to eliminate the environmental risk induced by the combined pollution (tris-(2-chloroisopropyl) phosphate (TCPP) and Cd 2+ ). The prepared material was characterized by X-ray diffraction (XRD), UV–vis diffuse reflectance spectra (UV-DRS), Raman imaging spectrometer (Raman), N 2 adsorption/desorption isotherm and X-ray photoelectron spectroscopy (XPS). In the combined pollution system, the prepared TiO 2 simultaneously exhibited a higher adsorption and photocatalytic activity for Cd 2+ and TCPP at neutral condition, respectively. The adsorption of Cd 2+ and photo-degradation of TCPP by mesoporous TiO 2 followed pseudo-second-order and pseudo-first-order kinetics model, respectively. The removal efficiency of TCPP was improved from 67% to 100% when the concentration of co-existed Cd 2+ increased from 0.5 mg L −1 to 2 mg L −1 , due to the fact that the adsorbed Cd 2+ on the surface of TiO 2 scavenged electron and thus inhibited the photo-generated electron-hole pairs recombination. In addition, six degradation intermediates were determined by high resolution mass spectrum (HRMS) and potential transformation pathways of TCPP under the co-existence of Cd 2+ were proposed. The results suggested that rapid and high-efficient simultaneous removal of Cd 2+ and TCPP was feasible, which laid the basis for the remediation of other combined pollution in the future.
研究领域:
环境科学
·
材料科学
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DOI
PubMed
高影响因子
POLYHEDRON
·
2019
·
IF 2.284
Qingchun Zhang,Bo Jin,Shufan Feng,Tian Zheng,Xiaofang Wang,Zhicheng Guo,Rufang Peng
There is a growing interest in the development of new iron ligands as novel promising therapeutic strategies for neurodegenerative disorders. In the article, a new tripodal hexadentate tris(dopamine) ligand, containing three dopamine chelate moieties which were attached to a cyanuric chloride molecular scaffold, has been synthesized and fully characterized by NMR, FTIR and MS. The solution thermodynamic stability of the ligand with Fe III , Mg II and Zn II ions was investigated. The results demonstrated that the ligand exhibited effective binding ability and improved selectivity for Fe III ion. The high affinity could be attributed to the favorable geometric arrangement between the ligand and Fe III ion coordination preference. The ligand also exhibited high antioxidant activity. Hence, the ligand could be used as potential chelating agent for iron overload situations.
研究领域:
生物化学
·
药物化学
·
医学
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高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2017
·
IF 5.401
Tongmou Geng,Zongming Zhu,Xie Wang,Hongyu Xia,Yu Wang,Dengkun Li
Two thiophene-based and carbazole-based conjugated microporous polymers (PTPATTh and PTPATCz) with triphenylamine core structural monomers were synthesized via straight forward anhydrous ferric chloride oxidative coupling polymerization. We first explored the fluorescent sensing performance of thienyl CMPs for picric acid (PA) and investigated comparatively the porosity and fluorescence sensing property for PA/p-nitrophenol (NP). Thanks to the propeller-like structure, high porosity, extended π-conjugation and electron-rich characteristics, the both CMPs exhibited strong fluorescent emission properties and worked as fluorescent chemosensors toward electron-deficient nitroaromatic analytes. The suspension of PTPATTh and PTPATCz given rise to the high luminescence, and showed a white and yellow emission in both THF and DOX excited under 365 nm using a UV lamp, respectively. Though BET surface area values and response speed of PTPATTh (594 m 2 g −1 ) are lower than that of PTPATCz (894 m 2 g −1 ), PTPATTh display higher selectivity for tracing PA than PTPATCz in DOX and THF. In short, the PTPATTh may be a new kind of material for detecting PA.
研究领域:
材料科学
·
化学
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高影响因子
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