COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
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2026
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IF 5.4
Zhengshen Bao,Dehong Xu,Hailong Peng,Changqing Xia,Shixing Wang,Weili Li
Efficient recovery of Au (III) from aqueous wastewater is of great significance for resource utilization and environmental protection. Herein, azine-functionalized Zr-based MOFs (hereinafter referred to as AZA-Zr-MOFs) were prepared via a facile one-pot solvothermal route using 2,2'-diamino-4,4'-(4-amino-1,2,4-triazole-3,5-diyl) dibenzoyl acid as the organic linker. The abundant triazole and amino groups on the MOF surface provide multiple active sites for multi-nitrogen synergistic coordination, thus enhancing the selective capture of Au (III) in aqueous solution. The obtained AZA-Zr-MOFs exhibit a high maximum uptake capacity of 1176 mg/g for Au(III), along with remarkable selectivity and excellent cycling stability (＞90 % efficiency after 5 cycles) over a wide pH range (2.0~9.0). Combined with experimental analyses (X-ray photoelectron spectroscopy (XPS), zeta potential, Fourier transform infrared spectroscopy (FTIR)) and density functional theory (DFT) calculations, the liquid-phase adsorption mechanism of Au (III) is clarified as a synergistic effect of amino-assisted reduction (Au (III)→Au (0)), nitrogen-centered coordination on the MOF surface, and electrostatic interfacial interaction via protonated amino groups. This work provides a feasible preparation method for MOF-based adsorbents and reveals the key role of surface functional groups in the interfacial adsorption of Au (III), which has potential application value for Au (III) recovery from actual aqueous wastewater.
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ANALYTICA CHIMICA ACTA
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2025
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IF 6
Feng Zhang,Sen Zhang,Xing Liu,Wei Gao,Jun Luo,Yi-fan Pan,Wei-Juan Zheng,Xin Hu,Hong-zhen Lian
Background Glycoproteins are critical in various biological processes and attract lots of attention of researchers. It still remains a challenge to detect glycopeptides by mass spectrometry because of their low abundance with heterogeneity and lability, as well as signal suppression by non-glycopeptides. The boronate affinity-based enrichment is an effective solution for detecting cis -diols-containing compounds including glycopeptides in complex matrices. However, there has not been any report about absolute quantitation of boron in the absorbent materials for glycopeptides, which obstructed the tailored design of boronate affinity materials and deeper understanding of interaction mechanisms. Results This work presents the development of a boronic acid-functionalized magnetic zirconium metal-organic framework (mMOF–AAPBA) with actual boron content for specific capture of glycopeptides. The synthesized nanocomposite could enrich glycopeptides by magnetic solid-phase extraction (MSPE) via the synergistic effect of hydrophilic interaction and boronate affinity. After full characterization including quantitative analysis of boron by laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS), mMOF–AAPBA was applied as MSPE absorbent to capture glycopeptides. Under the optimized conditions, it could enrich 28 glycopeptides both from horseradish peroxidase and immunoglobulin digests, with a limit of detection of 1 fmol μL −1 coupled with matrix-assisted laser desorption/ionization time of flight mass spectrometry. The boronate affinity absorbent also possessed great ability of anti-interference and good reusability. Furthermore, it possessed high performance in enriching glycopeptides in real samples including human saliva and traditional Chinese medicine injections. Significance In the preparation of the boron-containing nanocomposites, there is a special interest that an accurate protocol was established to assay boron based on LA-ICP-MS assisted by home-made matrix reference substances for the first time. These findings highlight the quantitative boron-containing mMOF–AAPBA as a robust affinity material for glycopeptide enrichment in real biological samples, offering potential applications in glycoproteomics and other cis -diols compound related researches.
研究领域:
分析化学
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生物化学
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纳米技术
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质谱学
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糖蛋白质组学
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Journal of Environmental Chemical Engineering
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2026
·Vol. 14
·期 6
·125315
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IF 7.5
Huifang Zhao,Chunhong Liu,Wang Liao,Yingjie Zhao
Green synthesis of defective Zr‑MOFs employed mercaptoacetic acid (MAA) as a modulator. • MAA dosage regulated framework defects, pore structure, and surface properties. • The optimized DPM-2 achieves a high adsorption capacity of 356.4 mg·g⁻¹ with equilibrium reached within 60 min. • Electrostatic, chemical, and hydrogen‑bonding interactions collectively enhanced p-ASA adsorption. Defect modulation is an effective strategy for optimizing the pore architecture and active-site accessibility of metal-organic frameworks (MOFs). Herein, a series of defective Zr-MOFs was synthesized in an aqueous medium using mercaptoacetic acid (MAA) as an acid modulator and is denoted as DPM-X (DUT-67(PZDC)-MAA-X, where X denotes the volume of MAA added). Structural characterization revealed that the MAA dosage played a key role in regulating framework defect formation, thereby altering the pore characteristics and surface chemical properties of the synthesized MOFs. Benefiting from abundant adsorption sites and a special pore structure, DPM-2 exhibited a high uptake of 356.4 mg·g −1 for p-ASA and reached equilibrium within only 60 min. Moreover, the material showed remarkable resistance to interference from coexisting ions and retained excellent regeneration performance during repeated use. The adsorption mechanism involves the synergistic action of electrostatic attraction, chemical bonding, and hydrogen-bonding interactions. The proposed green defect-engineering strategy provides an effective route to regulate the structural properties of Zr-MOFs, offering a practical approach to tailoring pore structure, surface chemistry, and adsorption performance. Download: Download high-res image (162KB) Download: Download full-size image Mercaptoacetic acid-modulated defect-engineered Zr-MOFs for rapid and high-capacity p-arsanilic acid removal
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JOURNAL OF ALLOYS AND COMPOUNDS
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2024
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IF 5.8
Wangchang Geng,Pengfei Song,Xinrou Cao,Libing Duan
Metal oxides derived from metal-organic frameworks (MOFs) can maintain the porosity and unique structure of MOFs, giving them significant development potential in the field of gas sensing. In this study, bimetallic Ni/Zr-MOFs solid microspheres were synthesized via the solvothermal method, and NiO/ZrO 2 composites with p-p heterostructure were further prepared through an annealing process. The morphology, structure, specific surface area, and pore size of NiO/ZrO 2 composites were analyzed using a series of characterization techniques. The gas sensing performance study showed that the NiO/ZrO 2 -2 sensor exhibited higher response (32.3–100 ppm), lower detection limit (7.2 ppb), shorter response/recovery time (55 s/83 s), and excellent repeatability to triethylamine gas at the operating temperature of 240 ℃. Additionally, within a specific range (1–200 ppm), a strong linear relationship was observed between the response value and the gas concentration for the NiO/ZrO 2 -2 sensor (R 2 =0.9588). This study is expected to provide a valuable reference for designing high-performance triethylamine sensors.
研究领域:
材料科学
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化学传感器
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ACS Applied Materials & Interfaces
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2023
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IF 9.5
Li Wang,Yi Pan,Zhengwu Wang,Yuanfeng Wang,Xinlin Wei
Organophosphorus pesticides (OPPs) are extensively used in agricultural production, and the contamination caused by their residues has raised significant concerns regarding potential threats to human health. Herein, a novel fluorescence nanoprobe based on an enzyme-mediated silver nanoparticle-modified metal organic framework (AgNPs@PCN-224) was successfully prepared for the rapid detection of OPPs. Initially, AgNPs@PCN-224 were synthesized by reducing silver nitrate (AgNO3) using sodium borohydride (NaBH4) embedded into luminescent PCN-224. This triggered the inner filter effect, leading to fluorescence quenching. Meanwhile, under the catalysis of acetylcholinesterase (AChE) and choline oxidase (CHO), acetylcholine (ATCh) was decomposed to hydrogen peroxide (H2O2), which could destroy AgNPs to form Ag+ released from PCN-224 for fluorescence recovery. Instead, fenitrothion, an OPP, inhibited AChE activity, allowing the quenched fluorescence to be reactivated. Under the current optimum conditions, the fluorescence intensity had a good correlation (Y = −728.5370X + 2178.4248, R2 = 0.9869) over a dynamic range of fenitrothion concentrations from 0.1 to 500 ng/mL, with an LOD of 0.037 ng/mL. In addition, the anti-interference ability and robustness of the proposed sensor was verified for the monitoring of fenitrothion in tea with recoveries of 87.67–103.72% and the relative standard deviations (RSD) < 5.43%, indicating that the system has excellent prospects for OPP determination in practical applications. Furthermore, this work provides a universal platform for screening other enzyme inhibitors to detect OPPs.
研究领域:
分析化学
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环境科学
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生物医学
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JOURNAL OF MEMBRANE SCIENCE
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2024
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IF 8.4
Ting He,Shuang Yao,Dejian Chen,Zhaoyun Sun,Xiaoyun Wang,Keyi Wang,Jiangwei Chen,Qingguo Li,Rizhi Chen,Yawei Wang,Zhaoliang Cui
Membrane oxygenator performs lung function in the Extra-corporeal Membrane Oxygenation (ECMO) system. In the clinical use, to ensure the balance of gas exchange of patient’s body, the gas-blood exchange membrane is required to possess CO 2 /O 2 selectivity, which is suggested to be in the range of 10-12. In our work, the molecular dynamics simulation results displayed that the amino-functionalized Zr-MOFs provides fast transport channels for CO 2 molecules because of the enhancement of the adsorption and diffusion ability for CO 2 . Therefore, we chose organic ligands with abundant CO 2 -philic groups to synthesize target amino-functionalized Zr-MOFs, and then dispersed them into medical-grade PDMS solution to study the separation performance of CO 2 /O 2 . On the basis of constructing anti-leakage coating layer, biomimetic gas channels were designed to increase the clearance rate of CO 2 . Experimental results exhibited that the CO 2 /O 2 selectivity of (NH 2 ) 2 -UiO-66/PDMS MMM was as high as 11.19, which was basically consistent with the simulation results. The obtained amino-functionalized Zr-MOF/PDMS coating layer displayed favorable biocompatibility and biosafety. Meanwhile, the construction of biomimetic channel solves the difficult problem of CO 2 removal in PMP membrane, which verifies the feasibility of applying porous materials to gas-blood exchange membranes in the ECMO system.
研究领域:
材料科学
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生物医学工程
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分子动力学模拟
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膜技术
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
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2021
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IF 8.128
Fan Xiao,Ming Cao,Rongrong Chu,Xiaoyu Hu,Wenxiong Shi,Yingbo Chen
A new type of composite membrane was prepared through the vacuum filtration self-assembly, in which, graphene oxide (GO) was the basic material, and the horizontal insertion material is product of perylene-3, 4, 9, 10-tetracarboxylic dianhydride (PTCDA) and UiO-66-NH 2 (PTCDA-UiO-66-NH 2 ). The leading role of Π-Π conjugate, auxiliary effect of hydrogen bonding during membrane preparation have been confirmed through Fourier transform infrared spectroscopy (FTIR), UV–visible spectrophotometer, Raman spectroscopy, and X-ray diffraction (XRD). The prepared GO@PTCDA-UiO-66-NH 2 membrane had new nodular structure compared to GO membrane by scanning electron microscopy (SEM) and atomic force microscopy (AFM), which promoted the water transport. In addition, the insertion of PTCDA-UiO-66-NH 2 narrowed the actual filtration spacing between GO sheets, and PTCDA-UiO-66-NH 2 could also adsorbed dye laterally. Experiments showed that the permeance of GO@PTCDA-UiO-66-NH 2 membrane was 1.7 times of GO membrane, and the removal of methyl blue, congo red, crystal violet and disperse black 9 was close to 100%. Under extreme pH, high salt concentration and multiple recycling, its separation ability was still excellent. The GO@PTCDA-UiO-66-NH 2 membrane constituted a unique synergistic structure of vertical-screening and horizontal-adsorption, which successfully overcame the trade-off effect and obtained excellent stability of structure and performance. Therefore, GO@PTCDA-UiO-66-NH 2 membrane had great potential in practical applications.
研究领域:
环境科学
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材料科学
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SENSORS AND ACTUATORS B-CHEMICAL
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2019
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IF 6.393
Baoshan He,Xiaoze Dong
In this work, the feasibility of a novel sensitive electrochemistry aptasensor for the detection of patulin (PAT) using hierarchically porous metal organic [email protected] blue connection aptamer as signal tags was demonstrated. The substrate electrode of the aptasensor was prepared by electrodeposited gold nanoparticles (AuNPs) on chitosan-zinc oxide nano flower-modified electrode. Subsequently, the complementary single-stranded DNA was attached to the surface of the modified electrode by Au-S bond. Signal tags self-assemble on the surface of modified electrodes by aptamer-cDNA binding, while methylene blue as mediator for electrochemical detection. Thanks to the large specific surface area provided by zinc oxide nano flower, the electrode can load more signal tags and AuNPs to achieve signal amplification. In presence of PAT, Apt preferentially binds to PAT, causing dissociation of some Apt-cDNA and releasing some signal tags leading, resulting in decreased electrical signals. Under optimal conditions, the change in electrochemical signal was proportional to the logarithm of PAT concentration, from 5 × 10 −8 -5 × 10 -1 μg mL −1 , and the detection limit was estimated to be 1.46 × 10 -8 μg mL -1 . The aptasensor exhibited aceptable reproducibility, renewability, long-term stability and specificity. Moreover, aptasensor was reliable in determination of PAT in spiked apple juice samples.
研究领域:
分析化学
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纳米技术
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电化学
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食品安全
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生物传感器
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MICROCHIMICA ACTA
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2026
·Vol. 193
·期 3
·184
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IF 5.4
Tan Long,Xiao Rui,Wu Di,Hu Lianzhe,Zhang Yan,Qi Wenjing
A fast fluorescent dual-emission platform for sensitive detection of sodium dehydroacetate (SDHA) in food is established utilizing bimetallic organic frameworks (Eu@Zr-MOFs). Eu@Zr-MOFs show two fluorescent emissions at 430 nm and 616 nm under single excitation wavelength of 290 nm. Two peaks separated by 180 nm help to eliminate environmental interference and improve the accuracy. In the presence of SDHA, fluorescent intensity at 430 nm and 616 nm shows fluorescent quenching within 1 min. Fluorescent lifetime results show that fluorescent quenching is a static quenching mode. Fluorescent quenching may be ascribed to the diketone structure of SDHA coordinated with Eu 3+ and internal filtering effect. The logarithm of fluorescent intensity (lg I 430 nm * I 616 nm ) has linear relationship with the concentration of SDHA from 0.1 µM to 200 µM with a limit of detection of 31.6 nM. More conveniently, it also achieves visual detection of SDHA through fluorescent color by portable UV lamp and smartphone “color capture” mode. The platform is applied to detect SDHA in fermented and baked food samples. Thus it is an efficient and sensitive fluorescent ratio method for SDHA detection with fast response, high selectivity and accuracy. Graphical
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Analytical Methods
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2026
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IF 3
Long Jing,Zheng Liu,Mengyu Su,Qirong Lu,Xiangfei Kong,Guo-Cheng Han,Xiaoyan Wang
On-site rapid food safety testing is an important means of market supervision. A "Dual-response-Reverse" (one signal increases while the other decreases) type biomass carbon quantum dots(G-BCQDs)/Zr-MOFs ratiometric fluorescent paper-based sensor was designed for the visual detection of spermine concentration (SPM, a representative of biological amines).G-BCQD (emitting at 477 nm) and Zr-MOF (emitting at 537 nm) exhibit reverse fluorescence responses to spermine, namely quenching and enhancement, respectively, thus enabling fluorescence ratio detection. The smartphone was connected with the ratiometric fluorescent paper-based sensor to quantitatively detect the concentration of spermine. The results showed that there was a linear relationship between the concentration of spermine in the range of 0.1-220.0 μM and the R' value of RGB values, and the linear equation was R' = 0.3740CSPM + 141.75 (R2 = 0.9913). The detection limit of the method was 19.93 μM. Shrimp samples were selected to evaluate the practicability of the ratiometric fluorescent paper-based sensor for detecting spermine concentration. The results of the spiked recovery experiment showed that the recovery rate of the shrimp samples was in the range of 90.97-101.14%, and the relative standard deviation was less than 2.15%, indicating that the ratiometric fluorescent paper-based sensor had high accuracy and precision and was shown to be applicable for detecting SPM in spoiled samples and thus for monitoring spoilage.
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ACS Applied Materials & Interfaces
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2022
·
IF 10.383
Chuan Zhou,Bo Yuan,Shouxin Zhang,Guang Yang,Lin Lu,Heguo Li,Cheng-an Tao
Zirconium-based metal–organic frameworks (Zr-MOFs) have been considered as prospective materials for the degradation of nerve chemical warfare agents (CWAs) but show poor catalytic performance toward blister agents. Moreover, the powder issues and the poor adsorption capability also remain as the major challenges for the application of Zr-MOFs in practical CWA detoxification. Herein, a series of defected granular UiO-66-NH2 metal–organic gels are synthesized via adjusting the amount of added concentrated hydrochloric acid for the decontamination of 2-chloroethyl ethyl sulfide (2-CEES), a sulfur mustard simulant. The half-life of 2-CEES decontaminated by defected granular UiO-66-NH2 metal–organic gels can be shortened to 7.6 min, which is the highest reported value for MOFs under ambient conditions. The mechanism of decontamination is that the amino group on the linkers in UiO-66-NH2 MOGs undergoes a substitution reaction with 2-CEES to yield 2-(2-(ethylthio)ethylamino)terephthalic acid, which is less toxic and fixed in the frameworks. The recycling test corroborates that the granular UiO-66-NH2 xerogels possess good stability and reusability. Static adsorption and desorption tests show that UiO-66-NH2 xerogels possess a high 2-CEES vapor adsorption capacity of 802 mg/g after exposure for 1 d and only 28 wt % desorption capacity after air exposure for 7 d. The dual function of ultrafast degradation and high adsorption capability provide a firm foundation for using UiO-66-NH2 xerogels as a future protection media.
研究领域:
化学战剂
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材料科学
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环境化学
·
催化
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RSC Advances
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2020
·Vol. 10
·期 6
·3084-3091
·
IF 3.119
Caixue Lin,Hailu He,Yongqi Zhang,Mingyue Xu,Feng Tian,Ling Li,Yingxi Wang
In recent years, the construction of drug carriers that integrate diagnosis and treatment has become a new trend. In this article, a metal–organic framework (Zr-MOF) was synthesized and functionalized using acetaldehyde-modified-cystine (AMC) to form the functional drug carrier Zr-MOF/AMC which could be used to determine the concentration of glutathione (GSH) for cancer diagnosis, and to achieve pH/GSH dual-responsive release of methotrexate (MTX) for cancer therapy. The cleavage of the AMC disulfide bond by GSH generates two fluorescent molecules that produce strongly enhanced fluorescence, and the intensity is proportional to the GSH concentration. The green fluorescence of Zr-MOF/AMC in cancer cells proves that it can be applied in cell imaging to detect abnormal GSH concentrations for early diagnosis. In addition, MTX loaded on the Zr-MOF/AMC is released by the cleavage of the –S–S– and –CN– bonds at the high GSH concentration and low pH in cancer cells. This dual-responsive drug release helps to deliver drugs to cancer cells more precisely. All the experiments suggest that this novel type of pH/GSH dual-responsive Zr-MOF/AMC nanoparticle may serve as a new drug delivery system for cancer diagnosis and treatment.
研究领域:
生物医学工程
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纳米医学
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肿瘤学
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高影响因子
危险品化学品经营许可证（带存储）