Journal of Environmental Chemical Engineering
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2021
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IF 5.909
Bo Gao,Hairong Yu,Jingya Wen,Hongju Zeng,Ting Liang,Fang Zuo,Changjing Cheng
Dye pollution has become a serious threat to environment and human health. Although versatile hydrogels have attracted intensive attentions due to their outstanding adsorption properties, the ultrahigh adsorption capacity and mechanical property are still two critical challenges for the practical applications. Herein, a super-adsorbent poly(acrylic acid)/laponite (PAAc/Lap) nanocomposite hydrogel with ultrahigh mechanical property and adsorption capacity of methylene blue (MB) is prepared by incorporating physical cross-linking with sparse chemical cross-linking. The hydrogel possesses porous 3D network structures and a fairly high water penetration with 1360 times of swelling ratio, which can allow the internal adsorption sites to be fully exposed and facilitate the adsorption. The adsorption capacity of MB can reach up to 3846 mg/g, which is almost the first time that a PAAc-based adsorbent could display superior adsorption capacity of more than 3800 mg/g towards MB. Important factors affecting the adsorption are also investigated, and the adsorption behavior is well fitted by the pseudo-second-order model and Langmuir isotherm model. More importantly, the appropriate physical cross-linking and sparse chemical cross-linking in the polymeric network endows hydrogel with superior mechanical properties. The tensile stress and strain are as high as 1.18 MPa and 2192%, which can facilitate the expansive applications and practical treatment. Mechanism analyses illustrate that the electrostatic interactions and cation-exchange between the functional groups of hydrogel and MB molecules contribute to the extraordinary adsorption ability. The proposed PAAc/Lap hydrogel with ultrahigh adsorption capacity and mechanical property is highly promising as an efficient super adsorbent for water treatment .
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CARBOHYDRATE POLYMERS
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2019
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IF 6.044
Guodong Li,Dehai Yu,Zhaoping Song,Huili Wang,Wenxia Liu
It is a significant challenge to reduce the sheet formation time and simultaneously sustain high transparency and good formation of nanostructured paper made of cellulose fibrils. In this study, a new strategy was developed for expediting the filtration but avoiding the flocculation of cellulose fibrils by using polyvinylpyrrolidone (PVP) and Laponite as dispersants to reduce the viscosity of the cellulose fibril aqueous dispersion. By adding 0.5 % PVP and 0.2 % Laponite to the cellulose fibril dispersion, the sheet formation time was reduced from 135.3–53.0 min, and the transmittance of the nanostructured paper was increased from 82.8%–89.8 %. The addition of PVP and Laponite significantly reduced the roughness and density but improved the tensile strength of the nanostructured paper. This study provides an approach for simultaneously improving the drainability, transparency, tensile strength, and smoothness of cellulose nanostructured paper made of cellulose fibrils.
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LANGMUIR
·
2018
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IF 3.789
Jiabo Shi,Chunhua Wang,To Ngai,Wei Lin
Understanding accessibility and interactions of clay nanoparticles with collagen fibers is an important fundamental issue for the conversion of collagen to leather matrix. In this study, we have investigated the diffusion and binding of Laponite into the collagen fiber network. Our results indicate that the diffusion behaviors of Laponite into the collagen exhibit the Langmuir adsorption, verifying its affinity for collagen. The introduction of Laponite leads to a shift in the isoelectric point of collagen from ∼6.8 to ∼4.5, indicating the ionic bonding between the positively charged amino groups of the collagen and negatively charged Laponite under the tanning conditions. Fluorescence microscopy, atomic force microscopy, field-emission scanning electron microscopy, energy-dispersive X-ray spectroscopy, and wide-angle X-ray diffraction analyses reveal that Laponite nanoparticles can penetrate into collagen microstructure and evenly distributed onto collagen fibrils, not altering native D-periodic banding patterns of collagen fibrils. Attenuated total reflectance-Fourier transform infrared and Raman spectroscopy detections further demonstrate the presence of noncovalent interactions, namely, ionic and hydrogen bonding, between Laponite and collagen. These findings provide a theoretical basis for the use of Laponite as an emerging tanning agent in leather manufacture.
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FIBERS AND POLYMERS
·
2018
·Vol. 19
·期 3
·477-488
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IF 1.353
Peng Qingyan,Xu Pengjun,Xiao Shili
Fabrication of porous polymer membrane with controlled drug release and efficient antibacterial performances is of great interest in biomedical fields. In this study, Laponite (LAP) nanodisks were first used to encapsulate a model antibiotic drug, tetracycline hydrochloride (TCH). Then, drug-loaded LAP nanodisks with an optimized loading efficiency (85.3 %) were mixed with poly(L-lactic acid) (PLLA) polymer to form drug-loaded composite porous membrane via solvent coasting. The structure, morphology and swelling property of the porous membranes formed with varied solvent ratio of methylene dichloride (DCM) and dimethyl formamide (DMF) in the mixture solvent were characterized using scanning electron microscopy (SEM), Fourier transform infrared spectroscopy and swelling test. In vitro drug release behavior, the cytotoxicity and the antibacterial activity of drug-loaded composite membranes were evaluated. Results showed that the TCH release was dependent on the physical structure of PLLA membrane and the presence of LAP nanodisks effectively weakened the initial burst release of TCH, and improved the sustained release property of porous PLLA membrane. The released TCH of TCH/LAP/PLLA 3:1 and TCH/LAP/PLLA 4:1 was 10.0 % and 5.3 % within initial 1 h, respectively. More importantly, the porous TCH/LAP/PLLA membrane was cytocompatible and displayed considerable antibacterial activity, solely associated with the loaded TCH drug, confirming its potential utility in wound dressings and tissue engineering.
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BIOMACROMOLECULES
·
2024
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IF 5.5
Yan Fang,Yukai Lin,Linyu Wang,Yunxiang Weng,Qinhui Chen,Haiqing Liu
Hemostatic powder is widely employed for emergency bleeding control due to its ability to conform to irregularly shaped wounds, ease of use, and stable storage. However, current powders exhibit limited tissue adhesion and insufficient support for thrombus formation, making them easily washed away by blood. In this study, a hybrid powder (QAL) was produced by mixing quaternized chitosan (QCS) powder, catechol-modified alginate (Cat-SA) powder, and laponite (Lap) powder. Upon addition of QAL, the blood quickly transformed to a robust and adhesive blood gel. The adhesion strength of the blood gel was up to 31.33 ± 1.56 kPa. When compared with Celox, QAL showed superior performance in promoting hemostasis. Additionally, QAL exhibited effectiveness in eliminating bacteria while also demonstrating outstanding biocompatibility with cells and blood. These favorable properties, including strong coagulation, adhesion to wet tissue, antibacterial activity, biosafety, ease of use, and stable storage, make QAL a promising emergency hemostatic agent.
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ACS Applied Nano Materials
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2024
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IF 5.3
Ling Lin,Yuanhao Luo
Water-based drilling fluids are prone to contamination by high temperatures and high salt, resulting in a deteriorated filtration performance of the drilling fluids, posing a significant threat to the safety of drilling operations. This study utilized N,N-dimethylacrylamide (DMAA), 2-acrylamido-2-methyl-1-propanesulfonic acid (AMPS), dimethyldiallylammonium chloride (DMDAAC), N-vinylpyrrolidone (NVP), and nanomaterials (nano-SiO2 and nanolaponite) to prepare a polymer nanocomposite NP-3 as a filtratef reducer for drilling fluids. The thermal stability evaluation of the polymer solution revealed that the thermal degradation temperature order of the different structural units of the polymer is DMAA < AMPS ≈ DMDAAC < NVP, and the temperature resistance of NP-3 in the solution is 220 °C. Evaluation of drilling fluid performance demonstrated that 3.5 wt % NP-3 enabled the drilling fluid to resist contamination from 15 wt % NaCl at 230 °C, with an American Petroleum Institute (API) filtration loss and high-temperature and high-pressure (HTHP) filtration loss after hot rolling of 4.2 and 22.0 mL, respectively. At high temperatures, the degradation of the polymer composite releases nanoparticles, which enhance the density of the filter cake, allowing for adjustable and enhanced control of filtration performance of drilling fluids under high-temperature and high-salty conditions.
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ACS Applied Materials & Interfaces
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2024
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IF 8.3
Siyuan Diao,Lili Meng,Christian Mark Pelicano,Jiajia Huang,Zhihong Tian,Feili Lai,Tianxi Liu,Shaokui Cao
Photothermal responsive hydrogels are widely used in bionic soft actuators due to their remote-controlled capabilities and flexibility. However, their weak mechanical properties and limited responsiveness hinder their potential applications. To overcome this, we developed an innovative laponite/MXene/PNIPAm (LxMyPN) nanocomposite hydrogel that is mechanically robust and exhibits excellent photothermally responsive properties based on abundant hydrogen bonds. Notably, laponite clay is used as a co-cross-linking agent to improve the mechanical properties of LxMyPN hydrogel, while MXene nanosheets are added to promote the photothermal responsiveness. The resulting L3M0.4PN nanocomposite hydrogel exhibits enhanced mechanical properties, with a compressive strength of 0.201 MPa, a tensile strength of 90 kPa, and a fracture toughness of 27.25 kJ m–2. In addition, the L3M0.4PN hydrogel displays a deswelling ratio of 73.6% within 60 s and experiences an excellent volume shrinkage of 82.4% under light irradiation. Furthermore, hydrogel actuators with fast response behaviors are constructed and employed as grippers capable of grasping and releasing target objects. Overall, this high-strength and fast-responsive hydrogel actuator is beneficial to paving the way for remote controlled soft robots.
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APPLIED SURFACE SCIENCE
·
2022
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IF 7.392
Nan Dai,Shuang Yi,Xiaotian Zhang,Li Feng,Hui Ding,Dan Song,Xiaoying Liu,Jinsong Rao,Yuxin Zhang
A typical adsorption modification method was employed to load ferrous ions on the Laponite@diatomite composite with 3D-2D morphology for photo-Fenton. Further, various characterization analyses were performed on the microscopic morphology and structure of the modified Laponite@diatomite. The removal ability of ferrous ion-modified Laponite@diatomite (Fe-La@D) photo-Fenton-oxidative cationic dyes under different raw material concentrations, H 2 O 2 content, MO concentration and light environment was discussed. Its reusability and photo-Fenton mechanism were further investigated. The study found that the ferrous ion-modified Laponite @diatomite is a catalyst with good photo-Fenton performance, and the MO degradation rate in 240 min can reach 99 % under the optimal reaction conditions. After modification, ferrous ions were successfully intercalated between the Laponite layers, and the forbidden band width of the material was reduced. And with the increase of catalyst dosage and H 2 O 2 content, the photo-Fenton reaction rate also increases. While the initial concentration of MO increases, the reaction rate decreases accordingly. Cycling tests demonstrate the structural stability and reusability of the catalyst. EPR spectra showed the generation of hydroxyl radicals , which are important substances in the degradation process. This work provides an idea for the synthesis of economical and ideal photo-Fenton catalysts, which has broad application prospects.
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Journal of Biological Engineering
·
2023
·Vol. 17
·期 1
·1-11
·
IF 5.6
Karimi Hajishoreh Negar,Dadashpour Mehdi,Akbarzadeh Abolfazl
Due to their outstanding structures and properties, three-dimensional (3D) hydrogels and nanoparticles have been widely studied and indicated a very high potential for medical, therapeutic, and diagnostic applications. However, hydrogels and nanoparticles systems have particular drawbacks that limit their widespread applications. In recent years, the incorporation of nanostructured systems into hydrogel has been developed as a novel way for the formation of new biomaterials with various functions to solve biomedical challenges. In this study, alginate-loaded Zinc- laponite—curcumin (Zn/La/Cur) nanocomposites were fabricated via ionic cross-linking. The prepared nanocomposite hydrogels were characterized via FTIR and FE-SEM. Moreover, energy dispersive x-ray spectroscopy (EDX) was used to study the elements of the Zn/La/Cur nanocomposite. The NIH3T3 fibroblast cell line was utilized for the MTT assay to determine the cell viability of the fabricated alginate-loaded Zn/La/Cur nanocomposites. MTT results demonstrated that there was no evidence of toxicity in the samples. These outcomes suggest that applying Al/Zn/La/Cur nanocomposite as a biological agent could be a novel tissue engineering strategy for treating soft tissue disorders.Graphical Abstract
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2019
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IF 4.784
Jinyu Li,Hao Pan,Sen Qiao,Yunjian Li,Jie Wang,Wei Liu,Weisan Pan
In the present investigation, we have synthesized the dalteparin which is a kind of low molecular weight heparin (LMWH) and possess the antitumor and antiangiogenic efficacy with carboxylates poloxamer 407 to form a heparin-poloxamer nanogel (HP copolymer). The complex HP is capable of enhancing the efficacies, minimizing the side effects of dalteparin and exhibiting a good thermosensitivity. Therewith, the synthetic Laponite RDS (LR) nanosilicate embarked with doxorubicin (DOX) at a satisfactory high drug entrapment efficiency was integrated with the complex HP and thus constituted a newfangled biocompatible injectable temperature-sensitive hydrogel. To our delight, consociation with 2.5 w/v % of LR nanodisks, HP at the concentration of 5 w/v % was sufficient to execute the solution-gel transition at animal heat, while 17.5 w/v % of P-407 was needed for fabricating the LR-P hydrogel. Simultaneously, LR-HP possesses a more preferable syringeability. Furthermore, the release behavior in vitro for the DOX@LR-HP demonstrated as extended and controlled manner, wherein, the drug-eluting profile was regulated by the LR nanocomposites. Moreover, based on synergic action of heparin and drug, DOX@LR-HP hydrogels demonstrated the best antitumor efficacy in vitro and in vivo. What is noteworthy is that through the course of treatment, the reflected anticancer efficacy direct at the established xenograft S180 sarcoma tumor was provided by the single administration of the DOX@LR-HP hybrid gel. This excellent long-term sustainable-anticancer function in vivo demonstrating the prospect of this nanohybrid-gel combination as an estimable focal drug delivery vehicle for treatment of cancer.
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BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
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2024
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IF 2.5
Baoguo Mi,Jitao Zhang,Hailan Meng,Yixin Xu,Jiajun Xie,Dingjun Hao,Lequn Shan
Reconstruction of bone defects has long been a major clinical challenge. Limited by the various shortcomings of conventional treatment like autologous bone grafting and inorganic substitutes, the development of novel bone repairing strategies is on top priority. Injectable biomimetic hydrogels that deliver stem cells and growth factors in a minimally invasive manner can effectively promote bone regeneration and thus represent a promising alternative. Therefore, in this study, we designed and constructed an injectable nanocomposite hydrogel co-loaded with Laponite (Lap) and vascular endothelial growth factor (VEGF) through a simplified and convenient scheme of physical co-mixing (G@Lap/VEGF). The introduced Lap not only optimized the injectability of GelMA by the electrostatic force between the nanoparticles, but also significantly delayed the release of VEGF-A. In addition, Lap promoted high expression of osteogenic biomarkers in mesenchymal stem cells (MSCs) and enhanced the matrix mineralization. Besides, VEGF-A exerted chemotactic effects recruiting endothelial progenitor cells (EPCs) and inducing neovascularization. Histological and micro-CT results demonstrated that the critical-sized calvarial bone defect lesions in the SD rats after treated with G@Lap/VEGF exhibited significant in vivo bone repairing. In conclusion, the injectable G@Lap/VEGF nanocomposite hydrogel constructed in our study is highly promising for clinical transformation and applications, providing a convenient and simplified scheme for clinical bone repairing, and contributing to the further development of the injectable biomimetic hydrogels.
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ACS Applied Electronic Materials
·
2024
·
IF 4.3
Xiaotao Liang,Wang Xu,Yanmin Ma,Xue Lv
Flexible hydrogel sensors have garnered significant interest owing to their biocompatibility and tissue similarity. Nevertheless, challenges such as inadequate mechanical strength, poor interface adhesion, lack of antimicrobial properties, and low conductivity impeded their practical utilization. This research aimed to address traditional hydrogels’ poor mechanical strength, interface adhesion issues, and lack of antibacterial properties, expanding their applications. Drawing inspiration from mussel adhesion, we crafted an innovative hydrogel using tannic acid (TA) as an adhesive, enhanced with ionic liquids (ILs) for the exfoliation of magnesium lithium silicate (Laponite) for mechanical improvement and carbon nanotubes (c-MWCNTs) for electrical enhancement. The prepared PAM/Lap-IL/TA/c-MWCNTs hydrogel showed a fracture stress of 461 kPa and a notable strain of 6800%, with an outstanding adhesive capacity (163 N/m). The prepared sensor can successfully monitor various human movements and exhibits good electrical conductivity (16.4 S/cm, GF = 3.15), quick reaction time (200 ms), and notable antibacterial activity. Crucially, this versatile conductive hydrogel has potential applications in electronic products and medical diagnostic health monitoring.
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