Polymers
·
2024
·Vol. 16
·期 7
·865
·
IF 4.7
Lianguo Wang,Pei Wang,Yifan Liu,Muhammad Atae Mustafa Mahayyudin,Rong Li,Weilun Zhang,Yilan Zhan,Zhihua Li
Poly(lactic-co-glycolic acid) nanoparticles (PLGA NPs) are versatile drug nanocarriers with a wide spectrum of applications owing to their extensive advantages, including biodegradability, non-toxic side effects, and low immunogenicity. Among the numerous nanoparticle preparation methods available for PLGA NPs (the hydrophobic polymer), one of the most extensively utilized preparations is the sonicated-emulsified solvent evaporation method, owing to its simplicity, speed, convenience, and cost-effectiveness. Nevertheless, several factors can influence the outcomes, such as the types of concentration of the surfactants and organic solvents, as well as the volume of the aqueous phase. The objective of this article is to explore the influence of these factors on the properties of PLGA NPs and their drug release behavior following encapsulation. Herein, PLGA NPs were fabricated using bovine serum albumin (BSA) as a surfactant to investigate the impact of influencing factors, including different water-soluble organic solvents such as propylene carbonate (PC), ethyl acetate (PA), and dichloromethane (DCM). Notably, the size of PLGA NPs was smaller in the EA group compared to that in the DCM group. Moreover, PLGA NPs showed excellent stability, ascribed to the presence of the BSA surfactant. Furthermore, PLGA NPs were co-loaded with varying concentrations of hydrophilic drugs (doxorubicin hydrochloride) and hydrophobic drugs (celecoxib), and exhibited pH-sensitive drug release behavior in PBS with pH 7.4 and pH 5.5.
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PubMed
高影响因子
JOURNAL OF THE ELECTROCHEMICAL SOCIETY
·
2021
·Vol. 168
·期 8
·087501
·
IF 4.316
Shiying Zhou,Peng Zhao,Jilin Zheng,Sha Chen,Mei Yang,Danqun Huo,Changjun Hou
Flexible electrodes play an increasingly important role in the development of portable and wearable electronics. Herein, a novel flexible and self-supporting electrode supported on active electrocatalyst (Au/Fe–Co@C–Nx/GO/CC) has been prepared for in situ detection of extracellular H2O2. The Fe, N co-doping of Fe–Co@C–Nx with abundant active sites promotes electron transfer efficiency, and Fe–Co@C–Nx nano-arrays with a unique spatial structure are beneficial for the deposition of Au nanoparticles (AuNPs). Graphene oxide (GO) serves as a chemical bridge to ensure that the nanomaterials grow more uniformly and firmly on the carbon cloth. Meanwhile, the flexible carbon cloth possesses stable mechanical and electrochemical properties. Based on these unique superiorities, this flexible electrode exhibits excellent sensing performance toward H2O2 with high selectivity and sensitivity, low LOD (0.56 μM), and wide linear range (from 5 to 21195 μM). Most importantly, the prepared electrode can adhere to cells for in situ and sensitive determination of H2O2 released from cells. Compared to detecting H2O2 in cell suspensions, in situ detection can capture the signal molecules more sensitively and effectively, avoiding the diffusion of H2O2 from the solution to the electrode surface. This flexible electrode has great potential in development of molecular detection and portable electronics.
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Journal of Materials Chemistry A
·
2021
·Vol. 9
·期 32
·17261-17269
·
IF 12.732
Jinji Liang,Chenhan Lin,Xiangcong Meng,Min Liang,Jie Lai,Xuhong Zheng,Quanzhuang Huang,Liying Liu,Zhicong Shi
Mn-based layered oxides, as potential cathodes for potassium-ion batteries (PIBs), face major challenges such as consecutive phase transition, serious capacity loss, and sluggish K+ transport kinetics. Herein, Co–Mg co-substituted K0.45Co1/12Mg1/12Mn5/6O2 is designed as a promising cathode material for PIBs to conquer the above issues in this work. Co3+–Mg2+ ions occupying the Mn3+ sites are confirmed to effectively alleviate the Jahn–Teller distortion induced by Mn3+ ions. P3-K0.45Co1/12Mg1/12Mn5/6O2 exhibits highly reversible single-phase structural evolution during the K+ deintercalation/intercalation. In contrast, the pristine K0.45MnO2 electrode experiences incompletely reversible structural variation from a P′3 to P3 phase. The increase of structural stability in the Co–Mg co-substituted sample is the main reason leading to improved cycling stability. Moreover, K0.45Co1/12Mg1/12Mn5/6O2 delivers better rate capability resulting from faster K+ diffusion compared to K0.45MnO2. Therefore, Co–Mg co-substitution is an effective strategy to enhance the structural stability and electrochemical properties of Mn-based layered oxides in PIBs.
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JOURNAL OF CHROMATOGRAPHY A
·
2012
·
IF 4.531
Zian Lin,Hui Huang,Xiaobo Sun,Yao Lin,Lan Zhang,Guonan Chen
A new polymer monolith with three modes of reverse-phase, hydrophilic and cation-exchange interaction was synthesized in 100 μm i.d. fused-silica capillary by in situ polymerization procedure. The pre-polymerization mixture consisted of glycidyl methacrylate (GMA) and 4-vinylphenylboronic acid (VPBA) as bifunctional monomers, ethylene dimethacrylate (EDMA) as crosslinker, 1,4-butanediol (BDO) and diethylene glycol (DEG) as binary porogenic solvents, and azobisisobutyronitrile (AIBN) as initiator. The resulting poly(GMA-co-VPBA-co-EDMA) monolith showed a relatively homogeneous monolithic structure, good permeability and mechanical stability. Different ratios of monomers and porogens were used for optimizing the properties of monolithic column. The column performance was assessed by the separation of a series of neutral solutes, charge solutes, phenols and anilines. Compared with poly(GMA-co-EDMA) monolith, the proposed monolith exhibited more flexible adjustment of selectivity in terms of hydrophobic, hydrophilic, as well as cation-exchange interaction in the same chromatographic conditions. High column efficiencies for benzene derivatives with 70,000–102,000 theoretical plates/m could be obtained at a linear velocity of 0.265 mm/s. The run-to-run, column-to-column, and batch-to-batch repeatabilities of the retention times were less than 8.23%. Additionally, the purposed monolith was also applied to efficient separation of alkaloids and proteins for demonstrating its potential in biomolecule separation.
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ENERGY
·
2025
·
IF 9.4
Shuai Guo,Xuhai Wang,Long Gao,Chenchen Zhao,Xingcan Li,Dean Song
This study proposes an integrated co-hydrothermal carbonization (co-HTC) strategy for simultaneously purifying hydrothermal wastewater and improving the combustion performance of co-hydrochar by co-processing tobacco stems (TSs) with chemically activated coal-gasification fine slag (CAC). TSs, a major agricultural residue, generate large volumes of organic-rich wastewater during HTC, while CAC exhibits high porosity and adsorption potential. The co-HTC was performed at 250 °C and 300 °C under varying TS: CAC mass ratios (1:0–1:3). At 250 °C and a TS:CAC ratio of 1:3, COD and TOC values declined from 18,144 mg/L and 8,686 mg/L to 10,383 mg/L and 4,350 mg/L, respectively, achieving removal rates of 42.78 % and 49.92 %. At 300 °C, the removal rates remained above 42 %, despite forming more low-molecular-weight organics. CAC promoted pore development in co-hydrochar, while dichloromethane extraction exposed additional micropores and cracks, enhancing surface reactivity. The introduction of CAC reduced aliphatic and carbonyl groups in both the hydrochar and the bio-oil phases, suggesting CAC's dual role in adsorbing unstable intermediates and catalyzing aromatization. Combustion characterization showed that with increasing CAC ratio, the burnout temperature of hydrochar increased by 40 °C (from 689 °C to 729 °C), while the flammability index and combustion stability index decreased. Dichloromethane extraction improved ignition temperature, maximum combustion rate temperature, and combustion uniformity by 20–45 °C, confirming enhanced reactivity after removal of secondary char. In conclusion, co-HTC of TSs and CAC offers a sustainable route for the integrated treatment of agricultural and industrial residues, providing both wastewater remediation and high-quality carbon materials. Optimization of operating conditions is essential to balance purification efficiency and fuel quality.
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CHEMICAL ENGINEERING JOURNAL
·
2025
·
IF 13.2
Cong Wan,Jianwen Zhang,Honglei Zhang,Min Liu,Yiming Li,Zijun Yan,Chengheng Pang,Tao Wu
The catalytic reduction of CO₂ into valuable chemicals and fuels is a promising strategy for mitigating global carbon emissions. This study explores the synergistic co-reduction of CO₂ and H₂O using nanoscale zero-valent iron (NZVI) as a dual-function catalyst. Under light irradiation at 300 °C, the CO₂ reduction rate increased by more than 10-fold compared to dark conditions, demonstrating significant photothermal synergy. The study reveals that NZVI undergoes a phase transformation, where Fe₃O₄ functions as a photocatalyst while Fe 0 serves as an electron donor, enabling a unique dual-functionality that facilitates efficient electron transfer. The addition of 10 vol% H₂ stabilizes the reaction, leading to a higher and more consistent CO yield. When investigating the simultaneous reduction of CO₂ and H₂O, we discovered competitive adsorption and reaction pathways that significantly influence product distribution. In-situ diffuse reflectance infrared Fourier transform spectroscopy (DRIFTS) and density functional theory (DFT) calculations revealed three distinct mechanistic pathways for CO₂ conversion: direct C O bond cleavage, a carboxylate-mediated pathway and bicarbonate-mediated pathway, with the carboxylate and bicarbonate pathways being uniquely promoted by H and OH from H₂O dissociation. The addition of H₂O into the CO₂ and H₂ reaction significantly enhanced CH₄ generation due to the extra H source from H₂O dissociation. These findings offer valuable insights into the competitive mechanistic pathways of CO₂-H₂O co-reduction and contribute to the design of more efficient iron-based catalysts for sustainable CO₂ conversion and water splitting in energy and environmental applications.
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高影响因子
ELECTROCHIMICA ACTA
·
2018
·
IF 5.116
Ze Chai,Chuanhai Jiang
The electrochemical/chemical growth of porous (Ni,Co,Cu)(OH) 2 was reported based on the corrosion behaviors of Ni-Co-Cu films in neutral salt spray . The films prepared by using electrodeposition were ternary solid solution alloys with a simple phase structure, strong texture, nanoscale grains, large microstrain and a large number of crystal defects . The unique microstructures coupled with extensive ion diffusion during the subsequent corrosion process facilitated the formation of ternary hydroxides with uniform and porous nanostructures . The ternary hydroxides composed of Ni-/Co-dominant hydrotalcite-like and Cu-dominant orthorhombic (Ni,Co,Cu)(OH) 2 could be efficiently prepared by motivating the transformation from oxide to hydroxide. The binder-free (Ni,Co,Cu)(OH) 2 electrode exhibited a high specific capacitance of 1738 F g −1 at a current density of 20 A g −1 and decent cycling stability. The electrochemical/chemical growth mode, uniform porous nanostructures and nature of the ternary hydroxides could account for the superior electrochemical performances. This work proposed a simple and green approach to prepare multicomponent hydroxides as novel electrode materials for rechargeable batteries and hybrid supercapacitors .
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高影响因子
ANALYTICA CHIMICA ACTA
·
2026
·
IF 6.1
Haoyuan Deng,Shan Li,Chunfei Bao,Daoyuan Zhao,Yubin Ding
Background Although sensor arrays are powerful for discriminating glycosaminoglycans, the construction of a sensor array is usually cost and labour inefficient. With the purpose to acquire a high dimensional response data using only a limited number of dyes, the rational assembly of fluorescent dye molecules may provide an alternative approach. We envision that co-assembling different dyes within a supramolecular structure can trigger multiple photophysical processes, which should produce high dimensional optical signals. Results A supramolecular AIEgen-porphyrin co-assembly is synthesized by assembling a negatively charged AIEgen ( TPE ) and meso-tetra(4-carboxyphenyl)porphine ( TCPP ) on the surface of a cationic polymer saying poly(diallyldimethylammonium chloride) ( PDDA ). With the co-assembly strategy, the aggregation-induced emission of TPE , the aggregation-caused quenching characteristic of TCPP , and especially, the Förster Resonance Energy Transfer efficiency from TPE to TCPP can be manipulated by a dynamic dye assembly approach. A sensor array is thus readily constructed by varying the loading ratio of TPE and TCPP on the surface of PDDA . Significance The sensor array is determined to be powerful for pattern recognition of various glycosaminoglycans even in 100% serum media through competitive compaction or removal of the aggregated TPE and TCPP dyes on the PDDA surface. It can be successfully applied for accurate and reliable detecting trace GAG analogues in Hep samples and identifying unknown GAG samples with an accuracy of 96.88%.
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高影响因子
JOURNAL OF MATERIALS SCIENCE
·
2026
·Vol. 61
·期 37
·27895-27908
·
IF 4.4
Li Jing,Wang Jin
CO is a key product of CO 2 electroreduction (CO 2 ER) and an important feedstock for the production of hydrocarbons and alcohols. Herein, we synthesized electrocatalysts by growing Cu nanocluster on manganese oxide (Cu n -Mn 3 O 4 ) for CO 2 ER. In 0.5 M KHCO 3 electrolyte using an H-cell, the optimized Cu 0.4 -Mn 3 O 4 achieved a Faradaic efficiency for CO (FE CO ) of 88.5 ± 2.3% and a current density of 14.3 ± 0.2 mA cm −2 at − 0.6 V vs. RHE, while substantially suppressing the hydrogen evolution reaction (HER). The better performance was due to the electrons transferred from Mn to CO 2 by Cu as a shuttle and anchored Cu nanoclusters shifted the d-band center toward the Fermi level, which was more conducive to the intermediate formation. In situ electrochemical attenuated total internal reflectance (EC-ATR) spectroscopy and density functional theory (DFT) calculations revealed the *COOH intermediate (1399 cm⁻ 1 ) along the CO 2 → *COOH → *CO → CO pathway. Moreover, the DFT calculations further demonstrated the Gibbs free energy barrier (ΔG) of the key steps in the CO 2 ER pathway and the corresponding intermediate configurations, which were used to reveal the relationship between the catalyst structure and CO 2 ER performance. The design of the metal/metal oxide electrocatalyst in this study provides a new perspective for the highly selective reduction of CO 2 to CO. Graphical
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ChemistrySelect
·
2026
·Vol. 11
·期 21
·e73559
·
IF 2.3
Xin Long,Shijie Zhou,Dong Liang,Mingdong Zhou,Liwei Sun,Yuehui Li
Room-temperature plasma-assisted catalysis represents an important pathway for CO 2 valorization. Rational design of catalysts tailored to plasma environment holds significant potential for improving catalytic efficiency. Unprecedentedly, we report a coordination-engineering strategy to fabricate the Fe/Cu mix-metal organic framework (Fe/Cu-MOF) catalysts for plasma-driven CO 2 dissociation into CO. Precise modulation during synthesis revealed an optimal Fe:Cu ratio of 0.44:0.56 to generating synergistic active sites favorable for CO production. The in situ-formed FeCu-based catalyst exhibited exceptionally high CO space-time yield of 32.3 mmol·gcat-1·h-1 under room-temperature plasma conditions. The coordination-tailored electronic structure enables the dynamic variations in the oxidation states of Fe/Cu upon plasma activation, thus facilitating sustained CO 2 activation. This work establishes atomic-level control of bimetallic sites as a powerful paradigm for plasma-catalytic systems. Graphical For the first time, Fe-Cu bimetallic metal-organic frameworks (MOFs) synthesized via a one‑pot solvothermal method were used for efficient decomposition of CO 2 into CO with excellent stability under nonthermal plasma (NTP). This integrated approach offers fundamental insights and technical support for the development of robust catalysts under plasma conditions.
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高影响因子
PHYSICA B-CONDENSED MATTER
·
2026
·
IF 3.2
Bangxing Li,Wei Li,Guojie Zhang,Yanghua Wang,Xiaolin Hu
In this study, cobalt copper co-doped bismuth vanadate (CuCo-BiVO 4 ) was firstly used for tetracycline (TC) degradation. The doped BiVO 4 with different Co/Cu ratio was systematically synthesized by the hydrothermal method. The results of the photocatalytic degradation shown that Co 0.02 Cu 0.01 Bi 0.97 VO 4 exhibited the optimal degradation activity, which may attribute to the smallest grain size (338 nm) of Co 0.02 Cu 0.01 Bi 0.97 VO 4 . The elemental distribution analysis confirms the coexistence of Cu 2+ and Co 2+ dopants. XRD and XPS analysis indicate that Cu 2+ or Co 2+ dopants replaced Bi 3+ in BiVO 4 . The band gap of Co 0.02 Cu 0.01 Bi 0.97 VO 4 was 2.35 eV, smaller than pure BiVO 4 , as calculated from the Tauc diagram. The highest degradation efficiency of 81.7% can be reached within 2 h. The rest degradation efficiency can reach about 70% of fifth recycling experiment, which shows good degradation stability of Co 0.02 Cu 0.01 Bi 0.97 VO 4 . Therefore, Co-Cu co-doped BiVO 4 stratage is a promising method for TC degradation.
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ChemCatChem
·
2026
·Vol. 18
·期 3
·e01844
·
IF 4.1
Xiao Lin,Hongsen Dong,Le Xu,Shipeng Ding
Co-based catalysts were reported to be active in CO 2 hydrogenation to CH 4 . Herein, we reported the selectivity of CoO x catalysts could be modulated from CH 4 to CO after modifying by MoO x , which was almost inactive in CO 2 hydrogenation. The strong interaction between CoO x and MoO x species in CoMoO x resulted in decent catalytic performance in CO 2 hydrogenation to CO, with the highest CO 2 conversion of ∼38% and a high CO selectivity of ∼99%. The strong interaction between CoO x and MoO x induced the formation of rich oxygen vacancy, which promoted adsorption of CO 2 on oxygen vacancies neighboring MoO x , while H 2 was activated in CoO x sites. Compared with CoO x and MoO x , bicarbonate species were detected during the in situ CO 2 hydrogenation to CO. This work illustrated the critical role of synergistic effect in tuning the selectivity in CO 2 hydrogenation.
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