CELLULOSE
·
2020
·Vol. 27
·期 15
·8827-8841
·
IF 4.21
Al-Ghamdi Youssef O.,Khan Shahid Ali
Abstract Performance of polymer-based Au catalysis depends on the size of Au particles and the structure of polymer host materials. In the current studies, the carboxymethyl cellulose-chitosan (CMC-CH) sheet was synthesized by layering CMC on CH sheet, while CMC-CH-CBV 780 zeolite Y (CMC-CHZY) sheet was synthesized by coating the CMC layer on a sheet of CH-incorporated CBV 780 zeolite Y (ZY). The CMC-CH or CMC-CHZY sheets were individually immersed in Au(III) salt solution, which was converted to Au 0 NPs by treating with NaBH 4 to synthesize Au/CMC-CH or Au/CMC-CHZY catalysts respectively. Both the synthesized Au catalyst activities were compared against the discoloration of methylene blue (MB) and Congo red (CR) dyes as well as the reduction of 4-nitrophenol (4-NP). It was revealed that Au/CMC-CHZY catalyst showed excellent catalytic performance against all the pollutants. Furthermore, the apparent rate constant k app (3.3 \(\times\) 10 − 1 min −1 ), of Au/CMC-CHZY catalyst was found higher against MB dye discoloration as compared to CR and 4-NP. It was also observed that MB discoloration followed pseudo-first-order while CR and 4-NP followed the zeroth-order kinetics. The catalyst alters the mechanism of a chemical reaction and so does the order of the reaction, therefore, observed different orders of reaction in the current study. Graphic abstract
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JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
·
2020
·Vol. 31
·期 16
·13111-13117
·
IF 2.22
Chakrabarti Chiranjib,Fu Qingshan,Ali Wajahat,Chen Xinghan,Zheng Jia,Qiu Yang,Yuan Songliu
In this investigation, a series of (1 − x ) Bi 1− y Ho y FeO 3 – x Ba 0.8 Ca 0.2 TiO 3 (0.25 ≤ x ≤ 0.4; y = 0.025) ceramic solid solutions were synthesized using a conventional solid-state reaction route. The primary goal of this study was to perceive the significance of substitution on the structural, magnetic, dielectric, and resistive properties of the ceramic solid solution. The investigation suggested the trace of weak ferromagnetism in all of the samples. A methodical XRD-based phase structural study revealed a presence of a morphotropic phase boundary (MPB) in the range of 0.3 ≤ x ≤ 0.35, showing robust dielectric properties in the MPB region, as verified by the dielectric measurements. A room temperature A.C conductivity study and activation energy calculation advocated an improved resistive property in the x = 0.3 sample.
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MICROCHIMICA ACTA
·
2019
·Vol. 186
·期 2
·1-9
·
IF 5.479
Zhang Kai,Cao Jinxuan,Wu Yongxiang,Hu Futao,Li Tianhua,Wang Ying,Gan Ning
A simple and highly sensitive fluorometric method is described for the determination of the antibiotic kanamycin (Kana) in food. Dual signal amplification is accomplished by making use of double Y-shaped aptamer DNA probes acting as a capture probes and signal amplification probes. The DNA probes were immobilized on a gold bar and on a magnetic bar, respectively. On addition of Kana, the Y-shaped aptamer probe captures Kana and then is disassembled to release two single-stranded DNAs. These trigger target recycling and HCR between the two bars simultaneously. As a result, many long duplex DNA chains are formed in the supernatant. After pulling out the bars and adding the fluorescent intercalating probe SYBR Green I, strong fluorescence (with excitation/emission peaks at 497/525 nm) is induced. The use of such double Y-shaped DNA probes obviously overcomes the unspecific signal amplification by HCR which increases selectivity and sensitivity. This is due to the fact that the hairpin of HCR is separated in being present in different arms of the Y-shaped probe. Under the optimal conditions, the assay has a limit of 0.45 pg·mL −1 for Kana. It was applied to analyze spiked milk, fish and pork samples.
The scheme represents a sensitive fluorometric aptamer-based method to detect kanamycin (Kana). It is making use of a double stirring bar-assisted dual amplification strategy with zero background. Abbreviations: apt: aptamer, AuNPs: gold nanoparticles, HCR: hybridization chain reaction.
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PubMed
高影响因子
TRANSACTIONS OF TIANJIN UNIVERSITY
·
2018
·Vol. 24
·期 3
·201-211
·
IF 0
Wang Fumin,Liu Mengchao,Zhang Xubin,Lv Guojun,Sun Mingshuai
In this study, we designed and synthesized a novel battery-type electrode featuring three-dimensional (3D) hierarchical ZnO@Ni
x
Co 1− x (OH)
y
core/shell nanowire/nanosheet arrays arranged on Ni foam substrate via a two-step protocol including a wet chemical process followed by electro-deposition. We then characterized its composition, structure and surface morphology by X-ray diffraction, energy-dispersive X-ray spectrometry (EDS), X-ray photoelectron spectroscopy, scanning electron microscopy (SEM), transmission electron microscopy, EDS elemental mapping. Our electrochemical measurements show that the ZnO@Ni 0.67 Co 0.33 (OH)
y
electrode material exhibited a noticeably high specific capacity of as much as 255 (mA·h)/g at 1 A/g. Additionally, it demonstrated a superior rate capability, as well as an excellent cycling stability with 81.6% capacity retention over 2000 cycles at 5 A/g. This sample delivered a high energy density of 64 W·h/kg and a power density of 250 W/kg at a current density of 1 A/g. With such remarkable electrochemical properties, we expect the 3D hierarchical hybrid electrode material presented in this work to have promising applications for the next generation of energy storage systems.
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ACS Applied Materials & Interfaces
·
2015
·
IF 6.723
Juan Li,Zheyu Shen,Xuehua Ma,Wenzhi Ren,Lingchao Xiang,An Gong,Tian Xia,Junming Guo,Aiguo Wu
By enabling nanoparticle-based drug delivery system to actively target cancer cells with high selectivity, active targeted molecules have attracted great attention in the application of nanoparticles for anticancer drug delivery. However, the clinical application of most active targeted molecules in breast cancer therapy is limited, due to the low expression of their receptors in breast tumors or coexpression in the normal and tumor breast tissues. Here, a neuropeptide Y Y1 receptors ligand PNBL-NPY, as a novel targeted molecule, is conjugated with anticancer drug doxorubicin encapsulating albumin nanoparticles to investigate the effect of Y1 receptors on the delivery of drug-loaded nanoparticles to breast cancer cells and its potential for breast cancer therapy. The PNBL-NPY can actively recognize and bind to the Y1 receptors that are significantly overexpressed on the surface of the breast cancer cells, and the drug-loaded nanoparticles are delivered directly into the cancer cells through internalization. This system is highly selective and able to distinguish the breast cancer cells from the normal cells, due to normal breast cells that express Y2 receptors only. It is anticipated that this study may provide a guidance in the development of Y1 receptor-based nanoparticulate drug delivery system for a safer and more efficient breast cancer therapy.
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高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2024
·
IF 13.3
Yunlong Wang,Jie Zhou,Yan Dong,Peng Wang,Ruiyang Zi,Honglan Zhang,Yingqiang Luo,Yan Zhang,Teng Wang,Yuhan Chen,Biao Hu,Houjie Liang,Zhihao Wei,Xiang Zhao
Constructing precise delivery systems to enhance the antitumor efficacy of drugs represents a pressing clinical practice need. The characteristics of suitable physiological stability, flexible tunable size, and highly programmable architecture make functional DNA scaffolds an ideal solution to this requirement. Here, we designed DNA oligonucleotide probes Y 1 , Y 2 and Y 3 to construct a smart-responsive Y-shaped DNA scaffold drug conjugate (sYDD). This sYDD incorporates two AS1411 aptamers, an apurinic/apyrimidinic (AP) site, a B-cell lymphoma-2 (Bcl-2) antisense oligonucleotide (ASO) and a doxorubicin (DOX)-carrying sequence. The Bcl-2 ASO and DOX within sYDD could be responsively released in tumor cells that exhibited high expression of apurinic/apyrimidinic endonuclease 1 (APE1) and microRNA-21 (miR-21). And the in vitro and in vivo experiments demonstrated that sYDD exhibited substantial antitumor efficiency. Moreover, the flow cytometry and RNA sequencing results proved that the proposed sYDD effectively activated immune responses. This strategy provides an alternative approach for designing synergistic chemo-gene drug conjugates, which facilitates the development of precision tumor treatment modalities.
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Journal of Environmental Chemical Engineering
·
2025
·
IF 7.2
Yating Jia,Jing Lu,Yongfen Long,Bin Hou,Yuancai Chen
Microbially synthesized palladium nanoparticles (bio-Pd 0 ) hold great promise for catalysis, but the catalytic activity of bio-Pd 0 relies heavily on its subcellular localization. Electron donors could affect enzymatic reduction efficiency of Pd(II) and control the subcellular location of bio-Pd 0 , yet the underlying mechanisms were unclear. Here, the regulatory mechanism of electron donors on Pd(II) reduction pathways in the non-model bacterium B. megaterium Y-4 was comprehensively investigated by multiple methodologies including cell fractionation, DPV/CV, XPS, FTIR, TEM, proteomics. Key findings revealed that membrane-bound hydrogenases drove periplasmic Pd 0 synthesis via biohydrogen, while the new one-electron extracellular transfer (EET) channel consisting of membrane-attached cytochromes ( ccsB ) and multi-heme cytochromes-bound flavin mediated the extracellular Pd(II) reduction. Notably, electron donors could regulate Pd(II) reduction routes, thereby altering the subcellular distribution of bio-Pd 0 . In lactate-added systems, the higher expression of these proteins related to EET processes (NADH dehydrogenase, membrane-attached cytochrome c, heme-based electron transfer proteins and flavodoxin) promoted extracellular Pd 0 formation (65.4 %). Whereas, in formate-added systems, hydrogenase-driven periplasmic Pd 0 synthesis (64.0 %) was facilitated due to more active formate dehydrogenase, hydrogenase and NADPH-reducing hydrogenase. Moreover, synergistical metabolism of formate and lactate balanced both pathways and maximized the apparent Pd(II) reduction efficiency (98.13 %). Proteomic analysis confirmed formate-specific energy rewiring and compensatory energy via Na⁺-translocating Rnf complex and V-ATPase overexpression. These findings significantly advance our understanding of microbial metal reduction by delineating a true dual-pathway strategy in a Gram-positive bacterium, highlighting the mechanistic diversity beyond model Gram-negative systems and offering new insights for harnessing non-model organisms in biocatalysis and nanoparticle synthesis.
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LWT-FOOD SCIENCE AND TECHNOLOGY
·
2022
·
IF 6.056
Chengtuo Niu,Lina Yang,Feiyun Zheng,Chunfeng Liu,Jinjing Wang,Xin Xu,Qi Li
This study aimed to provide a systematic analysis of the effect of environmental factors on the growth and volatile flavor compounds (VFCs) production ability of Zygosaccharomyces rouxii Y-8 and further elucidate its contribution to doubanjiang fermentation in different salinity. Lower salinity (0–9%), acidic pH (4.5–5.5), moderate temperature (25–35 °C) and air exposure favored the growth and VFCs accumulation of Z. rouxii Y-8, which also had higher concentrations of key jiang flavor contributing compounds benzene ethanol, 2-methoxy-phenol and pyrazines. Interestingly, samples with higher VFCs concentration were found to contain less kinds of VFCs. When inoculated into doubanjiang fermentation, Z. rouxii Y-8 showed critical roles on the formation of VFCs in doubanjiang . Among doubanjiang samples fermented in different salinity, doubanjiang with 9% salinity had the highest kinds of VFCs. Moreover, its flavor was more balanced and the jiang flavor was stronger. This indicated that the presence of adequate salinity was necessary for Z. rouxii Y-8 to produce critical VCFs responsible for doubanjiang flavor. The results would provide researchers and manufacturers with a deeper understanding of the characteristics of Z. rouxii Y-8 and rationales to utilize Z. rouxii Y-8 as starter to produce high quality BBFFs.
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Chemical Biology & Drug Design
·
2025
·Vol. 105
·期 5
·e70113
·
IF 3.3
Ming Tong,Meng Liu,Liang Chen,Yi-he Lin,Qing Zheng
Liver fibrosis is pathologically associated with ferroptosis. Osthole (OST) has good therapeutic effects on liver fibrosis. Our study sought to investigate the pharmacological effects of OST on ferroptosis in hepatic stellate cells (HSCs) during the development of liver fibrosis and define the mechanisms involved. The in vivo model of liver fibrosis was established by CCl 4 treatment. MTT and EDU assays were used to assess cell viability and proliferation, respectively. The interaction between myocyte enhancer factor 2A (MEF2A) and Y-box binding protein 1 (YBX1) was analyzed by dual luciferase reporter and chromatin immunoprecipitation (ChIP) assays. OST treatment alleviated CCl 4 -induced liver fibrosis in mice by activating ferroptosis. OST induced ferroptosis in HSCs and inhibited the activation of HSCs in vitro, while these effects of OST were reversed by MEF2A overexpression or YBX1 overexpression. Mechanistically, MEF2A activated the Wnt/β-catenin signaling by transcriptionally facilitating YBX1 expression. As expected, the inactivation of Wnt/β-catenin signaling or YBX1 knockdown could reverse the regulatory effect of MEF2A upregulation on the activation of HSCs and ferroptosis in OST-treated HSCs. OST mitigated liver fibrosis by inducing ferroptosis in HSCs and repressing the activation of HSCs through inhibiting the MEF2A/YBX1/Wnt/β-catenin axis.
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PubMed
高影响因子
JOURNAL OF POROUS MATERIALS
·
2025
·
IF 3.2
Dai Xiaojun,Cheng Yan,Wei Qiang,Zhou Yasong
In the petrochemical industry, a significant method of achieving high-value usage of polycyclic aromatic hydrocarbons in light cycle oil is the moderate hydrocracking of these hydrocarbons into C 6 -C 8 chemical raw materials. In order to prepare NiW-S supported catalysts, the impregnation technique was used to modify the small-crystal Y zeolites with P. The catalytic performance of the catalysts was assessed using naphthalene as the model chemical. The physicochemical characteristics of the catalysts and P-modified Y zeolites were examined in relation to the impacts of P modification. The results show that the introduction of P has a negative effect on the structural characteristics and acidity of Y zeolite, and this negative effect increases with the increase of P content. The introduction of P reduces the reduction temperature of the active metal of the catalyst and improves the reducibility of the active metal of the catalyst. Adding appropriate P species enhances the active phase characteristics of the corresponding Ni-W-S supported catalysts while weakening the metal-support interactions of the corresponding Ni-W-S supported catalysts. However, too much P species has a negative effect on the active phase characteristics of the catalysts. Naphthalene conversion and C 6 -C 8 selectivity were shown to be significantly influenced by the synergistic catalysis of acid sites and metal sites of the catalysts. The catalyst based on 2% P modified Y zeolite exhibited the best selectivity of C 6 -C 8 compounds. The yield of C 6 -C 8 of 2% P modified Y zeolite-based catalyst increased by 22.34% when compared to the unmodified catalyst. It is anticipated to serve as a guide for the high-value use of polycyclic aromatic hydrocarbons in light cycle oil in petrochemical industry.
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JOURNAL OF ALLOYS AND COMPOUNDS
·
2023
·
IF 6.2
Peng-Fei Li,Chun-Li Hu,Bing-Xuan Li,Fang Kong,Jiang-Gao Mao
Two UV inorganic yttrium selenite optical materials, namely, Y(HSeO 3 )(SeO 3 )(H 2 O)·(H 2 O) (1) and Y 2 (SeO 3 ) 2 (SeO 4 )(H 2 O) 2 ·(H 2 O) 0.75 (2), have been synthesized successfully by hydrothermal reactions . Of these, Y 2 (SeO 3 ) 2 (SeO 4 )(H 2 O) 2 ·(H 2 O) 0.75 (2) is a new mixed valent selenium oxide containing Se(IV) and Se(VI) cations simultaneously. Y(HSeO 3 )(SeO 3 )(H 2 O)·(H 2 O) (1) shows a 3D structure composed of 2D yttrium selenite layers linked by O−H···O bonds. Y 2 (SeO 3 ) 2 (SeO 4 )(H 2 O) 2 ·(H 2 O) 0.75 (2) exhibits a 3D structure composed of 2D yttrium selenite layers connected by SeO 4 tetrahedron. Y(HSeO 3 )(SeO 3 )(H 2 O)·(H 2 O) (1) crystallized in a chiral space group P 2 1 2 1 2 1 and could display a moderate SHG intensity about 0.7 times of the commercial KH 2 PO 4 (KDP). Its powder laser damage threshold quantity was estimated to be 120.2 MW/cm 2 , which is about 46.2 times that of AGS (2.6 MW/cm 2 ). UV–vis–NIR spectra reflectance spectra showed that these solids are wide band gap compounds with Eg of 5.5 and 5.1 eV respectively. Theoretical calculations disclosed that Y(HSeO 3 )(SeO 3 )(H 2 O)·(H 2 O) (1) is an indirect band gap structures and its bandgaps is determined by O and Se atoms.
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JOURNAL OF THE AMERICAN CERAMIC SOCIETY
·
2013
·Vol. 97
·期 3
·990-995
·
IF 2.107
Kuo Jiang,Songbai Liu,Yuan Li,Yaofei Li
Powders of zirconia doped with 8 mol% REO 1.5 (RE = Yb, Y, Gd, and Nd) were synthesized by using the sol–spray pyrolysis method. The effects of RE 3+ ionic radius on monoclinic (m) phase content of powders were investigated. The XRD results showed that the metastable tetragonal (t′) phase underwent a complete phase change to form m and cubic (c) phases after a heat treatment of 50–100 h at 1450°C. A cation size-dependent reduction in the m phase content of the REO 1.5 partially stabilized ZrO 2 powders was observed. The SEM–EDS analysis of the powders revealed that the RE 3+ concentrations in the c phases decreased with decreasing the RE 3+ ionic radius. These results indicate that the stabilizer concentration of the c phase can be attributed to RE 3+ ionic radii, resulting in different m phase contents. Compared to the REO 1.5 single doped ZrO 2 , the m phase contents of 8 mol% (RE 0.5 Yb 0.5 )–ZrO 2 (RE = Y, Gd, and Nd) powders were significantly reduced. The results prove that the stabilizer with a lower RE 3+ size is effective in reducing the m phase content of partially stabilized ZrO 2 after annealing at high temperatures.
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