Journal of Physical Chemistry C
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2023
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IF 3.7
Jun Luo,Ao Wang,Lichao Jia,Dong Yan,Mei Hu,Jian Li
For the improvement of commercial catalyst 13 wt % Cr-γ-Al2O3 for the dehydrogenation of light alkanes to olefins, 13 wt % Cr-x wt % Ce-γ-Al2O3 catalysts with x equaling 0, 2.5, 5, 7.5, and 10, named as 0Ce, 2.5Ce, 5Ce, 7.5Ce, and 10Ce, are prepared by the incipient wetness impregnation method, characterized by X-ray diffraction, transmission electron microscopy, Raman, UV–vis, X-ray photoelectron spectroscopies, and temperature-programmed reduction and evaluated for ethane dehydrogenation to ethylene. Their performance increases with Ce addition to 5 wt % and then decreases and attenuates with time. 5Ce demonstrates the highest dehydrogenation activity and better regeneration ability than 0Ce. It is found that the as-prepared 5Ce contains more active amorphous Cr6+ species and less crystalline Cr3+ species (α-Cr2O3) than 0Ce, other than the Ce species of CeO2. The reasons for the better dehydrogenation and regeneration performance of 5Ce are that the CeO2 particles in 5Ce physically separate the Cr species, promoting the formation of Cr6+ species, preventing their aggregation and migration to form less active α-Cr2O3 and inactive α-(Cr, Al)2O3, and preserving more active Cr6+ species in the as-prepared and regenerated catalysts.
研究领域:
催化化学
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化学工程
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材料科学
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石油化工
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MATERIALS LETTERS
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2018
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IF 2.687
Keke Sun,Chen Xu,Tianke Hu,Caixue Lin,Yifeng Wang,Yulin Li,Ling Li,Yingxi Wang
In this work, novel core-shell γ-Fe 2 O 3 /La-MOFs@SiO 2 nanoparticles were fabricated and characterized. The feasibility for multifunctional drug carrier was investigated. The cytotoxicity proved the high biocompatibility and the drug release experiments showed the excellent pH-responsive release. The magnetic nature and strong blue fluorescence indicated the potential use for magnetic target and magnetic resonance/fluorescence dual mode imaging.
研究领域:
纳米医学
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材料科学
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药物递送
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生物成像
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分子成像
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RENEWABLE ENERGY
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2026
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IF 9.1
Jianan Liu,Wei Wang,Xinran Ji,Aimin Li,Lei Zhang
Efficient conversion of lignocellulosic biomass into furan-based chemicals is crucial for sustainable biorefineries. This study presents a synergistic catalytic system combining ferric chloride (FeCl 3 ) with a γ-valerolactone (GVL)/H 2 O co-solvent, revealing the pivotal role of trace water in enhancing furfural production. Under optimized conditions (H 2 O:GVL = 2:28, 180 °C), the system achieved an apparent furfural yield of 109.5 %, calculated based on the theoretical furfural yield from the xylan content of corncob. Mechanistic insights elucidated that Fe 3+ disrupts biomass–solvent interactions, thus facilitating hemicellulose and cellulose depolymerization. The significant 5-HMF yield highlights the system capacity to effectively hydrolyze cellulose into glucose and subsequently convert it via Fe 3+ -catalyzed aldose–ketose isomerization and dehydration pathways. Isotopic labeling with [1– 13 C] and [6– 13 C] glucose confirmed that Fe 3+ catalyzes aldose–ketose isomerization, a critical step steering sugar conversion toward furanic compounds. Furthermore, 2D-HSQC NMR and TG-FTIR-GC/MS analyses revealed that the FeCl 3 –GVL/H 2 O system promoted lignin depolymerization into low-molecular-weight aromatics for enhancing lignin valorization. Together, these findings reveal that trace water lowers the activation energy to accelerate sugar release and modulates the hydrogen-bonding network to stabilize furfural, while the GVL-rich phase stabilizes reactive intermediates, suppressing side reactions and improving furfural selectivity. Compared to conventional mineral acid systems, the FeCl 3 –GVL/trace-water system offers superior selectivity and efficiency under optimized conditions for biorefinery of lignocellulosic biomass.
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ACS Photonics
·
2026
·Vol. 13
·期 16
·4824-4834
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IF 6
Qiu Yunping,Pan Yuzhu,Huang Qianqian,Zhang Yulian,Chen Jinbao,Liu Youwen,Wang Xin
MAPbBr 3 (MA = CH 3 NH 3 ) perovskite
single-crystal γ-ray detectors based on Schottky diodes typically
suffer from electrochemical reactions at the cathode under an applied
bias. A low-resistance contact could decrease the electrical field
near metal/MAPbBr 3 single crystals. However, it is difficult
to achieve highly conductive n-type/p-type layers made of MAPbBr 3 single crystals. In this work, we report that n-type and
p-type MAPbBr 3 can be achieved by incorporating heterovalent
dopants and adjusting the MABr:PbBr 2 molar ratio. Through
epitaxial growth, γ-ray PIN diodes consisting of n-type and
p-type layers are fabricated, which establish sufficient energy barriers.
The resulting γ-ray PIN diode (8.4 × 8.5 × 4.1 mm 3 ) exhibits a dark current of only 238 nA under a bias of −1000
V. Owing to the absence of a strong electric field near the cathode,
cathode stability is improved. The balanced charge transport property
is further confirmed by time-of-flight and Hecht analyses. The γ-ray
PIN diode achieves an energy resolution of 3.1% for 662 keV γ-ray
photons.
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
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2026
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IF 9.6
Ze Wang,Wenxiang Wang,Lifang Shi,Man Zhao,Wei Wen,Liwu Qiang,Shuai He,Na Gao,Qinyun Yan,He Xiao,Jianfeng Jia
A two-step strategy of electrosynthesis-solvothermal process builds NiMo/G composites with Ni-O-Mo bridges. • Mo acts as interfacial electron pump, locking Ni in high-valent state. • Electron modulation lowers γ-NiOOH formation barrier by ∼150 mV and CH 3 O → CH 2 O step to 0.46 eV. • NiMo/G delivers 320.6 ± 5.2 mA cm −2 and 15,638.9 ± 254.1 mA mg Ni −1 , enabling low-overpotential formate pathway. The intrinsic instability of the active γ-NiOOH phase severely limits the performance of nickel-based electrocatalysts for the methanol oxidation reaction (MOR). Herein, we report a Mo-induced interfacial electron pump strategy to stabilize the γ-NiOOH lattice and boost MOR efficiency. Via a distinctive two-step strategy of electrolysis and subsequent solvothermal reaction, we construct NiMo/graphene (NiMo/G) composites rich in Ni-O-Mo interfaces, where Mo centers continuously withdraw electrons from adjacent Ni sites, functioning as efficient electron sinks. This precise electronic modulation lowers the thermodynamic barrier for γ-NiOOH formation by ∼150 mV and optimizes the adsorption energetics for intermediates, reducing the energy barrier of the rate-determining *CH 3 O → *CH 2 O step from 0.68 to 0.46 eV, thereby directing the reaction along a low-overpotential formate pathway. Consequently, this optimized NiMo/G catalyst achieves exceptional area activity of 320.6 ± 5.2 mA cm −2 and mass activity of 15,638.9 ± 254.1 mA mg Ni −1 , respectively. This work establishes interfacial electron pump engineering as a general and powerful strategy for stabilizing high-valent active phases in advanced energy conversion and storage technologies. Download: Download high-res image (183KB) Download: Download full-size image
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FOOD CHEMISTRY
·
2026
·
IF 10.4
Xiaolu Zhou,Ling Xia,Yufei Hu,Gongke Li
Preparation of γ-Al2O3/Eu-BTC for catalytic sensing toward terpenes. • A cyclic cataluminescence array sensor based on k-values corresponding to terpenes. • Investigation of the k -value pattern on the variation of terpene composition. • Origin identification of 86 hop samples based on characteristic terpenes. Hops are crucial to beer flavor, but their geographically dispersed origins are prone to confusion, while the significant variation in terpene ratios among hops from different regions provides key support for its origin identification. In this study，γ-Al 2 O 3 /Eu-BTC composite was synthesized for cyclic cataluminescence array sensor to terpenes. The results showed that the corresponding reaction decay coefficients ( k -values) for myrcene, farnesene, and humulene were 24.3, 32.0, and 73.8, respectively, enabling terpene-specific fingerprinting. Binary and ternary terpene mixtures exhibited predictable k -value variations, with relative standard deviations below 9.6%. A rapid detection method for hops identification was developed and successfully applied to 86 samples from six different origins. The method demonstrated both feasibility and accuracy, highlighting its potential as a rapid, simple, and efficient technique for origin identification of hops and other aromatic plants. Download: Download high-res image (160KB) Download: Download full-size image
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INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
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2026
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IF 9.2
Yu-Zheng Wang,Shu-Qi Li,Zi-Kai Zhou,Chao-Jun Chen,Wei Yang,Si-Nuo Zhang,De-Zheng Yang
The development of mild and green ammonia synthesis is a significant and challenging research. In this study, a nanosecond pulse-driven coaxial double dielectric barrier discharge reactor was combined with M/γ-Al 2 O 3 (M = Co, Ni, Co–Ni) catalysts for efficient ammonia synthesis. Key parameters including pulse voltage, gas flow rate, and N 2 /H 2 molar ratio were systematically investigated. The Co–Ni/γ-Al 2 O 3 catalyst achieved the best energy efficiency of 1.11 g/kWh and a synthesis rate of 226.33 μmol g −1 h −1 under optimal conditions, which is 3.44 times higher than that of the plasma only system. Characterization revealed superior metal dispersion, smaller metal particle size, and larger specific surface area for Co–Ni/γ-Al 2 O 3 . Electrical diagnostics and optical emission spectroscopy (OES) showed that catalyst packing enhances discharge intensity and promotes key active species (N 2 ∗, N 2 + , and H α ). Synergistic effects between Co and Ni sites promote ammonia formation. This work provides new insights for designing high-efficiency plasma-catalytic ammonia synthesis systems.
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CHEMICAL ENGINEERING SCIENCE
·
2026
·
IF 5.1
Guanglin Cao,Xiao Chen,Huibin Liu,Weilin Shen,Changhai Liang
The catalytic reduction of nitroaromatic compounds to aromatic anilines is a widely employed route for producing high-value refined chemicals and large-scale commodities. Developing highly efficient catalysts represents a promising strategy to achieve continuous and selective hydrogenation of functionalized nitroarenes under flow conditions. In this work, γ-Al 2 O 3 @Ni/FeO x egg-shell microspherical catalysts featuring high atomic dispersion, high specific surface area, and tunable active sites are designed by strategically harnessing hydrotalcite-inspired characteristics, which integrates a Ni–FeO x interfacial synergy into an egg-shell architecture for continuous-flow selective hydrogenation. In the continuous flow selective hydrogenation of o -chloronitrobenzene, the γ-Al 2 O 3 @Ni/FeO x -3 egg-shell microspherical catalyst presents a turnover frequency (TOF) of 30.16 h −1 , substantially higher than those of γ-Al 2 O 3 @Ni and γ-Al 2 O 3 @FeO x . Compared with the uniform Ni 3 Fe 1 /Al 2 O 3 catalyst, the egg-shell catalyst also exhibits enhanced mass transfer efficiency. The egg-shell catalyst enables an increased presence of electron-rich Ni δ- sites and FeO x species rich in oxygen vacancies on the surface of γ-Al 2 O 3 microspheres. Due to the formation of Ni δ- -O v -Fe 2+ , the egg-shell catalyst exhibits remarkable H-spillover capability, significantly enhancing the selective hydrogenation of o -chloronitrobenzene to o -chloroaniline. The apparent activation energy of the γ-Al 2 O 3 @Ni/FeO x -3 catalyst is only 22.99 kJ mol −1 , much lower than those of other egg-shell catalysts, indicating the synergistic integration of metallic Ni sites and oxygen vacancies. In addition, the as-prepared γ-Al 2 O 3 @Ni/FeO x -3 egg-shell catalyst presents long-term stability over 80 h and broad substate scope. This work offers comprehensive guidance for the rational design of industrial egg-shell catalysts, as well as establishes a solid foundation for the continuous flow selective hydrogenation process, aimed at producing substituted anilines from functionalized nitroarenes.
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BRITISH JOURNAL OF PHARMACOLOGY
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2026
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IF 7.5
Mei Feng,Xin Yang,Kuo Yao,Ke-Fan Yang,Xiang-Yi Zhan,Ming-Sheng Zhou,Hui Jia
Background and Purpose Previous studies have found that activation of the γ-secretase/NICD-PXR/Notch pathway can induce Taxol resistance in triple-negative breast cancer (TNBC) to limit its therapeutic effect. Accordingly, inhibition of the γ-secretase/Notch pathway maybe an effective strategy to enhance Taxol chemosensitivity in TNBC. We have already found that cimigenoside (CG), the active ingredient of Cimicifuga dahurica (Turcz.) Maxim, can inhibit γ-secretase activity. Experimental Approach The dynamic interaction between the natural γ-secretase inhibitor CG and γ-secretase catalytic core presenilin-1 (PSEN-1) was revealed by molecular dynamics simulations and in vitro enzyme activity experiments. The biological characterisation and in vivo role of CG in increasing Taxol sensitivity of TNBC were investigated. The regulatory effect of CG on the γ-secretase/RBPJ-PXR axis was studied through dual luciferase reporter gene assays, nuclear cytoplasmic separation experiments, and western blot assays. Key Results CG stably binds to the PSEN-1 protein cavity to inhibit γ-secretase activity. In vitro studies showed that CG significantly enhanced the inhibition of cell proliferation, migration and invasion, as well as the promotion of apoptosis of MDA-MB-231/Taxol cells by Taxol. CG enhanced the inhibitory effect of Taxol on subcutaneous tumours and lung metastatic TNBC in vivo. Mechanistically, CG inhibited the transcriptional activity of RBPJ by targeting γ-secretase, interfered with the interaction between RBPJ and pregnane X receptor (PXR), down-regulated the expression of PXR-regulated metabolic enzymes and transport proteins, and enhanced the sensitivity of TNBC to Taxol. Conclusions and Implications We show that CG enhances the chemical sensitivity of TNBC by regulating the γ-secretase/RBPJ-PXR axis. Graphical
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PubMed
高影响因子
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
·
2026
·
IF 4
Ming Wu,Yu Liang,Hao Lei,Lin Li,Xia Zhang,Yi Yuan,Bing Li
BACKGROUND Due to weak stability and bioavailability, γ -aminobutyric acid (GABA) and naringenin (Nar), two agents with sleep-promoting activities, are limited in practical application. To improve their sleep-promoting efficacy, this study developed a stability-enhanced co-loaded liposomal system (GABA-Nar-Lip) as a lyophilized powder. RESULTS The non-lyophilized GABA-Nar-Lip exhibited good dispersibility, with an average particle size of 161.34 ± 1.68 nm, and achieved encapsulation efficiencies of 46.18 ± 0.32% (GABA) and 82.01 ± 1.33% (Nar), respectively. The stability of GABA-Nar-Lip was significantly enhanced after lyophilization with sugars (especially 0.10 g mL −1 trehalose) as cryoprotectants (CPAs), and maintained targeted release in the small intestine. The CPAs exerted cryoprotective effects by replacing water molecules and forming hydrogen bonds with soy phosphatidylcholine, thereby preserving the spherical structure and unilamellar vesicle morphology of the liposomes. In caffeine-induced zebrafish models, lyophilized GABA-Nar-Lip showed an inferior but still significant effect in sleep latency reduction. Moreover, it decreased nocturnal twitching activity and enhanced daytime locomotor activity on the following day, without the adverse effects associated with melatonin, such as poor sleep quality and reduced daytime activity. CONCLUSION The stabilized lyophilized GABA-Nar-Lip powder is a promising, safe sleep aid with balanced efficacy and no compromise to next-day performance, supporting its potential application in dietary sleep interventions. © 2026 Society of Chemical Industry.
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RENAL FAILURE
·
2025
·
IF 3
Neng Bao,Ming-Jia Gu,Qiu-Ya Huang,Hai-Jian Sun,Xue-Xue Zhu,Xin Gu,Jin Wang,Xiang Yu,Qing-Bo Lu,Ya-Fen Yu
Purpose This study aims to investigate the protective effect of baicalin on sepsis-associated acute kidney injury (SA-AKI) and its molecular mechanism.Materials and methods An SA-AKI mouse model was established via lipopolysaccharide (LPS) injection. Baicalin’s effects on renal function, oxidative stress, and apoptosis were evaluated using histopathology, dihydroethidium, and terminal deoxynucleotidyl transferase dUTP nick end labeling staining. Bioinformatics, molecular docking, ribonucleic acid (RNA) sequencing, and Western blotting were employed to investigate the role of baicalin in regulating the peroxisome proliferator‑activated receptor‑γ (PPAR-γ)/uncoupling protein 1 (UCP1) pathway. Human kidney-2 cells were used for in vitro validation.Results In this study, baicalin significantly ameliorated LPS-induced acute kidney injury by modulating the PPAR-γ/UCP1 signaling pathway. Both in vivo and in vitro experiments revealed that baicalin attenuates inflammation, oxidative stress, and apoptosis while restoring mitochondrial function. RNA sequencing analysis revealed significant upregulation of PPAR-γ/UCP1 in the baicalin-treated group. Further molecular docking and molecular dynamics simulations confirmed a stable interaction between baicalin and UCP1. Validation via small interfering RNA-mediated knockdown of PPAR-γ and UCP1 revealed that inhibition of the PPAR-γ/UCP1 pathway abrogated baicalin’s protective effects, highlighting the critical role of this pathway in mediating baicalin’s renoprotection.Conclusion Baicalin protects against SA-AKI by activating the PPAR-γ/UCP1 signaling pathway. This study provides new insights into the mechanisms through which baicalin mitigates kidney injury in sepsis, suggesting its potential as a therapeutic agent for SA-AKI.
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高影响因子
Journal of Materials Chemistry A
·
2025
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IF 9.5
Yanyan Lei,Lingyan Xu,Yanze Wang,Lixiang Lian,Chongqi Liu,Yingming Wang,Lu Liang,Zhentao Qin,Shuai Han,Wei Zheng,Qinzeng Hu,Xiaowang Liu,Tao Wang,Wanqi Jie
As a novel lead-free perovskite derivative material, zero-dimensional Cs3Cu2I5 crystals exhibit remarkable optical properties and hold great application prospects in the field of radiation detection. To further enhance the scintillation performance and detection efficiency, we fabricated high-quality, centimeter-level Cs3Cu2I5:Na+ single crystals using a low-cost anti-solvent method. Na+ doping in the Cs3Cu2I5 lattice optimizes the photoluminescence quantum yield (PLQY) to 95%, which can be attributed to enhanced exciton–phonon coupling and boosted self-trapped exciton fraction. Compared to the intrinsic crystal, the energy resolution and light yield of Cs3Cu2I5:5%Na+ under 137Cs γ-rays are improved by 22% and 10.5%, respectively. Under X-ray excitation, Cs3Cu2I5:5%Na+ crystals exhibit stronger RL intensity, faster response speed, lower afterglow and lower detection limit. Based on excellent X-ray detection capability, a breakthrough spatial resolution of 25.6 LP per mm@MTF = 0.2 is achieved for the Cs3Cu2I5:5%Na+@PMMA flexible film. Cs3Cu2I5:Na+ crystals boast superior optical performance, exceptional detection capabilities, cost-effectiveness and eco-friendliness, rendering them a highly competitive candidate for high-resolution γ-ray detection and flexible X-ray imaging.
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危险品化学品经营许可证（带存储）