ACS Applied Polymer Materials
·
2024
·
IF 4.4
Wenwen Wang,Aisen Jiang,Hao Zhang,Junjie Wang,Xiaoguang Li,Congang Fu,Xiaohan Yang,Ke Liu,Dong Wang
The growing demand for polymeric materials has encouraged industries and the academic community to develop materials with improved mechanical properties, particularly those that can be used in various fields. Polyamide 6 (PA6) is a versatile engineering plastic material with various advantageous properties; however, improving its toughness and hydrophobicity is conducive to expanding its application. In this work, α, ω-aminopropyl-terminated poly(methyltrifluoropropylsiloxane) prepolymer (APMFS) was synthesized for its outstanding flexibility and hydrophobicity. It was then covalently incorporated into a PA6 backbone through straightforward large-scale melt polymerization. The functionalized PA6 exhibited the highest breaking strength and toughness of approximately 59.6 MPa and 426.3 MJ/m3, respectively. Moreover, the impact strength of PA6-APMFS reached 63.7 kJ/m2, more than twice that of conventional PA6. The water contact angle was measured at its highest, 94°, with water absorption reduced to 0.5 wt %. Microfibers exhibited a very low wicking height of 7.5 cm. Subsequently, functionalized nanofibrous membranes and foams were applied for self-cleaning, oil/water separation, and thermal insulation, showcasing excellent potential for protective and water purification applications. This work illustrates the multifunctional application advantages of modified PA6.
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
·
2025
·
IF 1.3
Ying Liu,Miao Wang,Guang-Xiong Zhou
The threat posed by microorganisms to food safety in development necessitates the discovery of new antimicrobial agents. Here, we unravel the antifungal activity of 6-methoxydihydrosanguinarine (6-ME) derived from Hylomecon japonica. 6-ME disrupted the biofilm formation of Candida albicans (C. albicans). 6-ME could cause the blockage of filamentation and classical cyclic adenosine monophosphate (cAMP) signaling pathway is involved in this process. 6-ME downregulated the expression of EFG1, CDC35, RAS1, and TPK2, all of which are critical components of the cAMP pathway. Furthermore, 6-ME changed the membrane permeability of C. albicans and caused reactive oxygen species accumulation, leading to cell death.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CHEMISTRY & BIODIVERSITY
·
2025
·
IF 2.5
Yuanyuan Zhang,Haixin Liu,Xiang Xu,Xin Shen,Haolong Qi,Yilin Xing,Mengyi You,Tao Sun,Zhiqiang Cai,Xiaoyan Zhang
Leaning pillar[6]arene (LP6A) is an expanded version of pillar[6]arene (P6A), possessing not only the nanometer-sized cavity of P6A but also a unique desymmetrized leaning tower-like structure, which offers better structural flexibility and cavity adaptability. Here we report the first example of the utilization of imidazolium ionic liquid (IMIL) functionalized LP6A (LP6A-C10-IM-C8[NTf 2 ]) as a stationary phase in capillary gas chromatography (GC). The LP6A-C10-IM-C8[NTf 2 ] capillary column was prepared by the static coating method, showing medium polarity (average polarity 155) and high column efficiency (3758 plates/m). Using long alkyl chains modified LP6A (LP6A-C10) as a reference column, its retention behaviour and resolving performance were elucidated by a mixture of 30 analytes. Importantly, the LP6A-C10-IM-C8[NTf 2 ] column exhibited advantageous separation performance for the challenging isomers of halogenated benzenes, benzaldehydes, phenols, and anilines over the LP6A-C10 and commercial HP-5, HP-35, and DB-17 columns. In addition, the LP6A-C10-IM-C8[NTf 2 ] column has been used to determine the purity of isomer impurities in actual samples, demonstrating good potential in GC separations. Graphical This work reported the first example of utilization of imidazolium ionic liquid (IMIL) functionalized leaning pillar[6]arene (LP6A-C10-IM-C8[NTf 2 ]) as a stationary phase in capillary gas chromatography separations and obtained a high resolution performance for multiple anayltes.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Dermatologica Sinica
·
2025
·
IF 2.2
Peng Yan,He Ling,Yang Xiaoqiong,Zhao Aijie
Background: Androgenetic alopecia (AGA), a kind of nonscarring baldness, is an androgen-dependent autosomal dominant polymorphism. Compound glycyrrhizin (CG), a compound preparation-containing glycyrrhizin, aminoacetic, and methionine, has been used to treat alopecia areata. Objectives: Our study aimed to explore the role of CG in hair regrowth in testosterone-induced AGA mouse model and the proliferation of human hair dermal papilla cells (HDPCs) and the related molecular mechanisms. Methods: The AGA mouse model was established through the injection of testosterone. The in vivo therapeutic effects of CG on AGA were assessed by detecting skin color changes, hair growth time, average hair length, and histological score. Human HDPCs after CG treatment were subjected to CCK-8 assay to evaluate cell proliferation. The impacts of CG on growth factor expression and the Wnt/β-catenin signaling in mouse dorsal skins and HDPCs were determined by undertaking western blotting, reverse transcription-quantitative polymerase chain reaction, and immunofluorescence staining. The Wnt/β-catenin pathway inhibitor XAV939 was used to validate the beneficial role of Wnt/β-catenin pathway activation in CG-mediated hair growth. Results: Our results showed that CG facilitated new hair growth and increased hair follicle numbers on the depilated dorsal area of the model mice. Furthermore, CG administration upregulated p-GSK-3β, β-catenin, cyclin D1, Axin2, LEF1, fibronectin, and survivin levels in the dorsal skins of model mice. In vitro assays revealed that CG promoted cell proliferation, elevated the mRNA levels of growth factors-related genes (insulin-like growth factors-1 (IGF-1), fibroblast growth factor-2 (FGF-2), and hepatocyte growth factor (HGF)), and increased p-GSK-3β, β-catenin, cyclin D1, Axin2, LEF1, fibronectin, and survivin protein levels in HDPCs. Importantly, XAV939 treatment debilitated the promotion of CG on hair regrowth in model mice and human hair dermal papilla cell (HPDC) proliferation. Conclusion: The beneficial role of CG in hair regrowth in AGA mice and HDPC cell proliferation depends on the Wnt/β-catenin pathway activation and the subsequent growth factor production in hair follicles. These results imply the potential of CG in the treatment of AGA.
✓ 已验证
产品关联
DOI
高影响因子
ACS Applied Materials & Interfaces
·
2025
·
IF 8.2
Salah Naji Sufyan,Yusof A. Y. A. Mohammed,Chenglong Mu,Kashan Bashir,Ning Wen,Muhammad Mamoor,Xiuling Jiao,Dairong Chen,Ting Wang
Flexible piezoresistive pressure sensors are crucial for next-generation wearable electronics, yet achieving simultaneous high sensitivity, durability, and mechanical robustness remains a challenge. Herein, we report a high-performance piezoresistive sensor fabricated through the integration of two-dimensional MXene nanosheets with a hierarchically structured modified polyamide 6 nanofiber net (D-PA6 NFN) using scalable vacuum filtration. Benefiting from the synergistic combination of MXene’s excellent electrical properties, web-like architecture, the composite nanofiber tensile strength (52 MPa), and flexibility (40%), the resulting sensor exhibited good sensitivity (0.189 kPa–1), a rapid response/recovery time (14/13 ms), and an ultralow detection limit (4.2 Pa). Moreover, the device maintained stability over 12,000 compression cycles. The sensor precisely captured both subtle physiological signals (pulse waveforms) and large-scale dynamic motions (joint flexion). This work establishes a scalable strategy for engineering durable, high-sensitivity electronic skins, with immediate applications in advanced human-machine interfaces and real-time physiological monitoring.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
POLYMER DEGRADATION AND STABILITY
·
2025
·
IF 7.4
Xintao Ma,Haoyu Yang,Xiaoqi Zhang,Jing Xia,Chenglin Wang,Dongying Gong,Na Lin,Zihao Liu,Hao Liu,Suqin He,Miaoming Huang,Wanlin Xu,Wentao Liu,Chengshen Zhu
The escalating complexity of industrial applications, coupled with the growing imperative for energy efficiency and environmental safety, highlights the need for the development of multifunctional, bio-based polyamide materials. In this work, we report the synthesis of a novel bio-based polyamide (PA510/6/DT), characterized by exceptional flame retardancy, high transparency, and superior UV resistance. This material is synthesized via the copolymerization of bio-based pentylenediamine, sebacic acid, caprolactam, and 3,5-diamino-1,2,4-triazole (DT), DT acts as an ultra-efficient flame retardant and endowing PA510/6/DT with powerful flame-retardant properties. The resultant PA510/6/DT demonstrates a V-0 rating in the UL 94 test and exhibits significantly reduced smoke production upon combustion, ensuring enhanced fire safety. Notably, the incorporation of DT not only preserves the inherent mechanical integrity of the polyamide matrix but also imparts excellent UV shielding and maintains high transparency, addressing compatibility challenges commonly encountered with traditional flame retardants. Non-isoconversional kinetic analysis reveals that pyrolysis follows an interfacial reaction-controlled mechanism (R3 contracting sphere model), validated by high activation energies and char-layer formation. Furthermore, PA510/6/DT exhibits remarkable mechanical strength and exceptional thermal stability, making it a promising candidate for high-performance applications in fields requiring concurrent flame retardancy, optical clarity, UV protection, and environmental sustainability.
✓ 已验证
产品关联
DOI
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2024
·
IF 8.1
Zain Bairq,Ya Pang,Jia Li,Abdo Hezam,Paitoon Tontiwachwuthikul,Han Chen
The primary challenge hindering the widespread industrial adoption of amine-based CO 2 capture technology is the sluggish desorption rate of carbon dioxide (CO 2 ) and the substantial energy required in the regeneration phase. Despite considerable advancements aimed at reducing energy demands through novel amine solvents and process optimization, there remains a critical need for innovative solutions. This study introduces mesoporous silica nanoparticles KIT-6, along with super solid acid catalysts SO 4 2− /SnO 2 and SO 4 2− /ZrO 2 , to assess their impact on enhancing the desorption rate and reducing the energy consumption in the CO 2 capture process from rich monoethanolamine (MEA) at 96 °C. Our findings indicate that all the tested catalysts significantly expedite the regeneration process, reducing the energy required for regeneration up to 33.50 % and boosting the desorption rate by 150.25 % beyond what is achieved with MEA alone. KIT-6, in particular, displayed superior catalytic activity and energy efficiency in the desorption process. The catalysts SO 4 2− /ZrO 2 , SO 4 2− /SnO 2 , and KIT-6 improved the desorption rate by 20 %, 37.5 %, and 150.25 %, respectively, and cut down the energy required for regeneration by 11.10 %, 24.44 %, and 33.50 % respectively when compared to conventional aqueous MEA under the same conditions. Moreover, KIT-6 was subjected to ten cycles of CO 2 desorption testing to verify the cyclic robustness. A potential mechanism explaining the enhanced CO 2 capture facilitated by KIT-6 is also proposed within this work.
✓ 已验证
产品关联
DOI
高影响因子
ENZYME AND MICROBIAL TECHNOLOGY
·
2024
·
IF 3.4
Zi-Hao Zhang,Yun-Xing Liao,Xue-Ting Deng,Zheng-Bing Guan
Glucosamine (GlcN), as one of the important derivatives of D-glucose, is formed by the substitution of the hydroxyl group at position 2 of glucose with an amino group. As a bioactive amino monosaccharide, GlcN is known for its various biological effects, including immune enhancement, antioxidant, anti-inflammatory, hepatoprotective, joint pain relief, and alleviation of osteoporosis. These properties highlight the broad applications of GlcN and its derivatives in pharmaceuticals, cosmetics, food production, and other fields, underscoring their promising prospects. Thus, the efficient industrial production of GlcN is gaining increasing attention as well. Here, we report a novel biosynthetic method for GlcN, utilizing engineered Escherichia coli expressing glucosamine-6-phosphate deaminase (GlmD) to directly convert D-fructose into GlcN. The best mutant screened using the Morgan-Elson colorimetric method is the triple mutant G42S/G43C/G136T (designated as GlmD-ZH11), which exhibits approximately 21 times higher catalytic activity towards D-fructose compared to the wild type. Using the purified enzyme of GlmD-ZH11 in shaken flask fermentation for six hours, we achieved a conversion rate of 72.11 % from D-fructose to GlcN. To further elucidate the mechanism behind the enhanced activity of the GlmD-ZH11 mutant, we conducted hydrogen bond network analysis to investigate the hydrogen bond interactions between the mutant and fructose. Additionally, we performed molecular dynamics simulations to study the RMSD and RMSF curves of the mutant. The results indicate that the protein structure of the mutant ZH11 is more stable and binds more tightly to the substrate. Calculations of the solvent-accessible surface area and binding free energy suggested that Thr41, Ser42, Asp72, Gly137, and Ala145 may be key amino acid residues in the catalytic process of ZH11. Finally, based on these findings and the catalytic mechanism of the wild type, we hypothesized a potential catalytic reaction mechanism for the ZH11 mutant.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
POLYMER COMPOSITES
·
2019
·Vol. 41
·期 2
·494-504
·
IF 2.268
Weijie Ding,Yuming Wang,Jie Ying,Yue Li,Honglin Liu,Xiang Yuan,Hang Yu,Jikui Wang
Polydimethylsiloxane (PDMS)-modified Kaolin was prepared by the reaction between kaolin and PDMS. MC nylon 6/kaolin and MC nylon 6/kaolin-PDMS composites with different filler contents were prepared through in situ polymerization. Thermogravimetric analysis and differential scanning calorimetry analysis show that the feeding of kaolin improved thermal stability and crystallinity of nylon. When 1 wt% addition of kaolin-PDMS, the tensile strength and impact strength of the as-prepared composites reached a maximum value of 77.7 MPa and 4.5 kJ/m 2 , respectively, exhibiting remarkable mechanical properties. Meanwhile, the water absorption capacity of the as-prepared composites was greatly reduced by 60% with the addition of kaolin, and the modified kaolin possesses even better performances. The results show that the treated kaolin can greatly enhance the properties of cast nylon and has an outstanding application prospect.
研究领域:
材料科学
·
化学工程
✓ 已验证
DOI
高影响因子
JOURNAL OF CHEMICAL AND ENGINEERING DATA
·
2017
·
IF 2.323
Huanxin Li,Junwei Zhang,Yonghui Dou,Li Xu,Guoji Liu
Data of liquid–liquid equilibria (LLE) for water + 1,6-hexanediamine + 1-butanol and water + 1,6-hexanediamine + 1-pentanol ternary systems were determined at T = 298.2, 308.2, and 318.2 K under atmospheric pressure. The distribution coefficients and selectivity factors calculated from LLE data were applied to evaluate the feasibility and effectiveness of extracting 1,6-hexanediamine from the aqueous solution. The results showed that the selectivity factors decrease with the amount of 1,6-hexanediamine increasing in the aqueous phase, and the effect of temperature is insignificant in this study. The nonrandom two-liquid and universal quasichemical activity coefficient models were also applied to regress the experimental equilibrium data of the two ternary systems and the root mean square deviation values between the correlated and experimental results were lower than 0.7%. It turned out that these phase equilibrium behaviors can be described by the two models. Meanwhile, the binary model parameters were acquired from the relevant process simulations.
研究领域:
化学工程
·
物理化学
✓ 已验证
DOI
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2019
·
IF 3.131
Zongtang Liu,Congcong Ding,Pingting Gao,Yunxia Xu,Yufeng Sun,Xiaoju Wen,Jingtao Dai,Zhenghao Fei
For the first time, the dechlorination of 2,6-dichlorophenol (2,6-DCP) by carbon nanotubes supported Fe/Ni nanoparticles (CNTs-Fe/Ni) was studied to explore the practicability of environmental remediation. Removal capacity of CNTs-Fe/Ni for 2,6-DCP was enhanced obviously compared to Fe/Ni due to reduced aggregation of Fe/Ni nanoparticles .The removal efficiency increased as the increase of CNTs-Fe/Ni dosage and Ni loading, whereas it decreased as the increase of 2,6-DCP concentration. Weak acidic condition was considered to be advantageous to 2,6-DCP dechlorination. The dechlorination kinetics results suggested that the 2,6-DCP removal by CNTs-Fe/Ni accorded with pseudo-first-order equation. Moreover, carbon nanotubes as support accelerated the mass transfer of 2,6-DCP from solution to catalyst surface and promoted the formation of atomic hydrogen, which also led to an enhancement of reactivity of CNTs-Fe/Ni on removing 2,6-DCP.
研究领域:
环境科学
·
纳米技术
·
化学工程
✓ 已验证
DOI
高影响因子
COMPOSITES SCIENCE AND TECHNOLOGY
·
2022
·
IF 9.879
Longxuan Gao,Fei Yan,Shengtao Dai,Lianshuang Zhao,Junming Wang,Yu Liu,Yuhui Ao,Liu Liu
To improve the unsatisfactory interfacial adhesion of carbon fiber/polyamide-6 (CF/PA6) composites, a hyperbranched waterborne polyurethane (HWPU) sizing agent with high-solid content was designed. As a carboxy chain extender for HWPU, carbic anhydride-tris(hydroxymethyl)methyl aminomethane (CA-THAM) with a self-catalytic capacity was synthesized to accelerate the chain extension. The synthesized hyperbranched polyurethane exhibited low viscosity, along with a strong double-electron layer conformation after dispersing in water. The electrostatic repulsion between the latex particles effectively prevented agglomeration, delivering a high solid content of 58% for the sizing agent. The influence of different sizing agent concentrations on the wettability of CF as well as the interfacial properties of composites was systematically studied. Compared with unsized CF/PA6 composites, the interlaminar shear strength and flexural strength of CF-1.5 wt%/PA6 composites were up to 60.3 MPa and 508.4 MPa, with an increment of 50.3% and 27.7%, respectively. Furthermore, the interfacial strengthening mechanism of sizing agent was discussed. The preparation of this high-solid content sizing agents was facile and environmentally friendly, which would hopefully reduce costs during the transportation.
研究领域:
材料科学
·
复合材料工程
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）