Journal of Materials Chemistry B
·
2017
·Vol. 5
·期 15
·2823-2831
·
IF 4.543
Dan Zhao,Xiaoqing Yi,Jiaqi Xu,Gongdao Yuan,Renxi Zhuo,Feng Li
Using the host–guest interaction between β-cyclodextrin (β-CD) and adamantane (Ad), and borate formation between phenylboronic acid (PBA) and cis-diols, a smart pH-responsible targeting drug delivery nanovehicle, PBA–PEG–CD/Ad-lys(Diol)–PCL, was prepared via one-step self-assembly. Under physiological conditions, the targeted PBA function could be restrained by binding PBA with diol components located at the interface of self-assemblies, and hydrophilic PEG segments could be shielded simultaneously. When the environmental pH decreased, the PBA groups could be unbound and exposed on the surface of self-assemblies, leading to recovery of its targeted function, as shown using fluorescence spectroscopy, in vitro cell toxicity, and uptake. Under acidic conditions, PBA–PEG–CD/Ad-lys(Diol)–PCL/Dox showed significantly increased uptake and toxicity toward HepG2 cells in comparison with the control group. The smart vehicles were further utilized to test their efficiency in overcoming drug resistance in chemotherapy. Compared with free Dox, PBA–PEG–CD/Ad-lys(Diol)–PCL delivered six times more Dox into MCF-7/ADR cells and showed greater toxicity toward the ADR cells. As a result, this may be a facile strategy toward constructing efficient targeting vehicles through the rational utilization of noncovalent interactions.
研究领域:
药剂学
·
纳米技术
·
药物递送系统
·
癌症研究
✓ 已验证
DOI
PubMed
高影响因子
npj Science of Food
·
2025
·Vol. 9
·期 1
·262
·
IF 7.8
Mou Linyun,Li Jianlong,Lu Ya
Cherries are highly susceptible to spoilage after harvest due to physiological and biochemical changes. This poses considerable challenges to food safety. Common fungal pathogens responsible for decay include Aspergillus niger and Cladosporium cladosporioides . Citral, an efficient antifungal agent, is thought to combat these pathogens through interactions with phytase (phyA) and N-myristoyltransferase (NMT), a hypothesis explored through molecular docking simulations. Using the Independent Gradient Model based on Hirshfeld partition (IGMH) analysis, it was found that citral encapsulated within α -cyclodextrin metal-organic frameworks ( α -CD-MOFs) forms strong van der Waals forces and exhibits hydrogen bonding. These interactions enhance the stability of the composite material. Incorporating citral-loaded α -CD-MOFs into a matrix of sodium alginate and pullulan resulted in a novel composite film. This film exhibits significantly improved flexibility and tensile properties, which is beneficial for fruit packaging. Meanwhile, the Higuchi and Ritger–Peppas models both indicate that citral is released by diffusion from a uniform polymeric matrix. When applied to cherry preservation, the film exhibited significantly better cherry preservation at 4 °C than at 30 °C ( P < 0.05). Simultaneously, the combination of low temperature with the film’s barrier properties and sustained antimicrobial release synergistically inhibited microbial growth and fruit metabolism, effectively delaying spoilage and supporting its application in both cold-chain and ambient-temperature transport.
研究领域:
食品科学与技术
·
采后生理学
·
高分子材料
·
活性包装
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抗菌递送系统
·
分子模拟
✓ 已验证
产品关联
DOI
PubMed
高影响因子
FUEL
·
2021
·
IF 6.609
Yong Wei,Guijian Liu,Biao Fu,Yuan Liu,Xuan Xue
Fine particulate matter (PM) emitted from coal-fired power plants (CFPPs) has aroused widespread environmental and human health concerns. Cadmium (Cd), as one of the prime toxic air pollutants, which exists in fine PM intensifies its toxicity. In this research, three particle sizes of PM (PM 1 , PM 2.5 , and PM 10 ) at the outlet of electrostatic precipitator (ESP), along with feed coal, bottom ash, and ESP ash, were collected from a 300-MW pulverized CFPP. Results showed that Cd was more enriched in the fly ash than in bottom ash. With the PM diameter decreasing, the relative enrichment index (REI) value of Cd increases from 2.30 to 7.84. The concentration of Cd was found to be intimately related to Ti in the PM. Abundant Ti-rich particles were identified in the PM 1 , having quite different chemical compositions as compared to particles larger than 2.5 μm. The major processes governing the formation of Ti-rich particles included melting of silicate-bound Ti and heterogeneous condensation of gaseous Ti from the decomposition of organic-associated Ti in coal. The transformation behavior of Cd to PM in a coal combustion process was discussed based on its occurrence mode in coal, thermodynamic property, and the possible interactions with ash particle compositions. The retention of Cd (g) by Ti-rich particle were probably dominated by chemisorption at high temperature; at lower temperature, physical adsorption or condensation may be the primary mechanisms for capturing CdCl 2 (g).
研究领域:
环境科学
·
化学
✓ 已验证
DOI
高影响因子
ENVIRONMENTAL TECHNOLOGY
·
2021
·
IF 3.247
Yan-Qin Yang,Min-Hua Cui,Jian-Chao Guo,Jing-Jing Du,Zhi-Yong Zheng,He Liu
In this study, biochars were produced by co-pyrolysis of rice husk and sewage sludge, the environmental risk of heavy metal (Pd and Cd) in the biochars was assessed. Co-pyrolysis resulted in a lower yield but a higher C content compared with sewage sludge pyrolysis alone, the relative contents of Pb and Cd in biochars were declined. Co-pyrolysis process transformed the bioavailable heavy metals into stable speciation. The environmental risk assessment codes of Pb and Cd were reduced by 1–2 grades. The co-pyrolysis technology provides a feasible method for the safe disposal of heavy metal-contaminated sewage sludge.
研究领域:
环境科学
·
土壤学
✓ 已验证
DOI
PubMed
高影响因子
ANALYTICA CHIMICA ACTA
·
2021
·
IF 6.558
Shuqi Zhou,Liubing Kong,Xinyi Wang,Tao Liang,Hao Wan,Ping Wang
Citric acid (CA) has been considered as a biomarker of urolithiasis due to its vital suppression role in urinary stone formation. Most analytical methods for detecting CA are complicated and require expensive equipment. Herein, a colorimetric method based on sodium dodecylsulfate (SDS) modified AgNPs was presented for convenient and portable detection of CA in urine. By detecting the absorption of the solution color, the quantitative detection of CA can be achieved. The pH value of SDS-AgNPs, concentration of Al 3+ and incubation time were optimized. Under optimal conditions, the method has the detection range of 1–10 mg/L, with a limit of detection (LOD) of 0.21 mg/L. Moreover, a self-developed portable CD(Compact Disk)-spectrometer (CDs) was established for detecting CA with a LOD of 0.49 mg/L featuring high simplicity, low time cost and good portability. This method was also validated with good selectivity to CA. In addition, the artificial urine samples were also detected to verify the capability of the method and CDs. The results validated that the method integrating with the CDs can be a promising platform for citric acid detection that can be further used for early screening and prognostic monitoring of urolithiasis.
研究领域:
分析化学
·
医学诊断
·
纳米技术
✓ 已验证
DOI
高影响因子
Journal of Materials Chemistry A
·
2018
·Vol. 6
·期 21
·9922-9929
·
IF 9.931
Yang Chen,Bohan Shan,Chengyin Yang,Jiangfeng Yang,Jinping Li,Bin Mu
Two environmentally friendly and efficient synthesis methods, NH3-assisted synthesis and solvent-evaporated conversion, have been developed for the synthesis of a series of M(NA)2 (M = Zn, Co, Cu, Cd; NA = nicotinate) flexible MOFs. The two-dimensional M(NA)2 (M = Zn, Co) and three-dimensional M(NA)2 (M = Cu, Cd) materials exhibit peculiar structural transformation. These frameworks can be obtained from dehydration of M(NA)2(H2O)4 (M = Zn, Co, Cu, Cd) which are zero-dimensional supramolecular structures. Interestingly, the structural transformation of M(NA)2 (M = Zn, Co, Cd) is reversible after liquid water adsorption. Due to the flexible structure of these MOFs, they exhibit abnormal NH3 adsorption properties. The two-dimensional Zn(NA)2 shows a gate-opening behavior for NH3 adsorption. Its layers opened at a pressure of 0.22 bar in the first cycle, resulting in a two-step NH3 uptake with a capacity of 10.2 mmol g−1 at 1 bar. The gate-opening pressure shifted to a lower value with cycles. Co(NA)2 has a huge NH3 uptake of 17.5 mmol g−1, which is top-ranking among the reported values. For the NH3 adsorption over Cu(NA)2 and Cd(NA)2, the adsorption rates increase and adsorption equilibrium is achieved faster after three cycles. Their maximum capacity at 1 bar is 13.4 and 6 mmol g−1, respectively. More importantly, all MOFs can be regenerated under vacuum and heating conditions of 150 °C for 70 min, and they all retained the capacity. The advantages of environmentally friendly synthesis, large adsorption capacity, and regenerable properties indicate that M(NA)2 (M = Zn, Co, Cu) are promising candidates for NH3 adsorption.
研究领域:
材料科学
·
化学工程
✓ 已验证
DOI
高影响因子
DESIGNED MONOMERS AND POLYMERS
·
2022
·
IF 3.718
Hong-Mei Liu,Xiao-Na Shang
Through the self-assembly reaction of 5-substituted isophthalic acid and bis(imidazolyl) ligands with Cd(II) ion or Zn(II) ion, two new coordination polymers with the chemical formulae of [Cd(5-meo-ip)(bmip)]n (1) and [Zn(5-pro-ip)(bip)]n·2 n(H2O) (2) (5-meo-H2ip = 5-methoxyisophthalic acid, 5-pro-H2ip = 5-propoxyisophthalic acid, bmip = 1,3-bis(2-methylimidazolyl)propane bip = 1,3-bis(imidazolyl)propane) were successfully obtained and structurally characterized by a series of characterization techniques. Moreover, compounds 1–2 show intense blue luminescence at room temperature. Furthermore, the assessment of their treatment activity on the uterine fibroids combined with ultrasound therapy was evaluated and the specific mechanism was investigated at the same time. Firstly, the effect of compound treatment on uterine fibroids apoptosis was detected via flow cytometry. Next, the apoptotic signaling pathway activation was detected through the Caspase-3 and Caspase-8 Activity Assay Kit.
研究领域:
材料科学
·
医学
·
生物化学
✓ 已验证
DOI
PubMed
高影响因子
ANALYTICA CHIMICA ACTA
·
2018
·
IF 5.123
Xingxing Wu,Shucheng Wu,Yingchun Li,Han Chen,Qunhui Yuan,Wei Gan
Lately, an “all-in-one” strategy via direct pyrolysis of protic salt has attracted great attention in the preparation of hetero-doped porous carbons due to its distinctive simplicity. However, protic salt derived carbons usually process large grain sizes thus hamper their applications. Herein, a protic salt derived N, S co-doped porous carbon (N, S-PC) with improved porosity was synthesized by nanocasting and carbonization of protic salt. In the nanocasting silica sphere was used as auxiliary template and an easily obtained protic salt ([pPDA][nHSO 4 ]) was served as C, N and S sources. The obtained N, S-PC contains rich N, S contents and hierarchical textural porosity, thus favors the electrochemical detection of toxic cadmium ions . The N, S-PC based sensor shows excellent sensitivity and selectivity for Cd(II) versus other metals, with a low detection limit of 0.1 μg L −1 (S/N = 3) over a wide concentration range of 4–80 μg L −1 . Applications of the N, S-PC based sensor for Cd(II) assay in tap water samples achieved results with good recoveries, indicating that the N, S-PC based electrode is promising in real sample analysis.
研究领域:
材料科学
·
环境科学
·
分析化学
✓ 已验证
DOI
PubMed
高影响因子
Inorganic Chemistry Frontiers
·
2026
·
IF 6.2
Zhongliang Gong,Xiaodong Yi,Xi-Gui Gao,Huwenyu Huang,Yu-Xin Ma,Zi-Xuan Liu,Jingmei Zhao,Lijuan Feng,Cheng-Yang Yue
The increasing demands in optoelectronic applications have driven the advancement of organic–inorganic hybrid metal halides (OIHMHs), owing to their exceptional optical transparency and high luminescence performance. In this work, three zero-dimensional OIMH single crystals of (C7H18N2)MBr4 (C7H18N2 = 1-propylpiperazine, M = Cd, Zn, and Mn) were prepared via a facile saturated crystallization method with adjustable luminescence properties. (C7H18N2)MnBr4 displays intensive green light emission with the highest photoluminescence yield (PLQY) of 54.93% originating from the d–d transition of Mn2+. Due to filled d orbital configurations of Zn2+ and Cd2+, (C7H18N2)CdBr4 and (C7H18N2)ZnBr4 exhibited blue light owing to their stronger self-trapped excitons (STEs) recombination. Furthermore, (C7H18N2)CdBr4 and (C7H18N2)ZnBr4 exhibited another red luminescence band after grinding, originating from defect-induced STEs. In addition, due to their excellent PL performance, the white LED fabricated based on (C7H18N2)MnBr4 and (C7H18N2)ZnBr4 has demonstrated a high color rendering index (CRI) of 88.2. This work not only provides a strategy for optimizing the photoluminescence performance by modulating metal ions within the same crystal structure of OIHMHs, but also provides insights into both intrinsic STE emission and the design of high-performance luminescent materials.
✓ 已验证
DOI
高影响因子
Analytical Methods
·
2019
·Vol. 11
·期 40
·5214-5221
·
IF 2.378
Mingyu Tang,Xiaodong Liu,Nannan Zhang,Jingyu Pang,Yu Zou,Fang Chai,Hongbo Wu,Lihua Chen
Herein, nitrogen and sulfur codoped carbon dots (N&S CDs) were prepared by a facile hydrothermal process and they could be introduced as a fluorescent probe for the determination of cadmium ions (Cd2+), yielding high sensitivity and excellent selectivity. The obtained N&S CDs exhibited bright blue fluorescence with a quantum yield of 40% and exhibited a fast responsive fluorescence quenching signal within 2 min toward Cd2+ in both ultrapure water and real water samples. The CDs responded to Cd2+, which acted as a quencher of blue fluorescence at 459 nm with the limit of detection of 0.018 μM in the range of 0.02–1 μM. The quenching fluorescence behavior was found to obey the static quenching effect (SQE). The low toxicity and good cell permeability of CDs were verified by cell experiments.
研究领域:
分析化学
·
环境科学
·
纳米材料
·
生物传感
·
环境污染监测
✓ 已验证
DOI
高影响因子
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
·
2024
·Vol. 31
·期 8
·11591-11604
·
IF 0
Lu Yuxi,Zeng Honghu,Lin Hua,Liang Yanpeng,Feng Mi,Zhou Zijian,Liang Zihao,Li Huawei,Chen Gongning
Since Cd(II) and As(III) have extremely opposite chemical characteristics, it is a huge challenging to simultaneously remove these two ions from aqueous solutions. Therefore, a novel iron sulfide-based porous biochar (FSB) was synthesized and used to evaluate its Cd(II) and As(III) removal performance and mechanisms. The characterization and batch experiments results indicated that FeS was successfully loaded on the surface of biochar and increased its adsorption sites. The iron sulfide-based porous biochar was very favorable for the removal of Cd(II) and As(III) in the weakly acidic environment. The maximum adsorption of Cd(II) and As(III) by FSB was 108.8 mg g −1 and 76.3 mg g −1 , respectively, according to the Langmuir and Freundlich isothermal adsorption model, and the adsorption equilibrium time was 12 h and 4 h, respectively, according to the pseudo-second-order kinetic model. In the coexisting ion system, Cd(II) adsorption was suppressed by Ca 2+ , Mg 2+ , and humic acid, but enhanced by PO 4 3− and As(III). As(III) adsorption was inhibited by PO 4 3− and humic acid. Precipitation and complexation are the predominant adsorption mechanisms of Cd(II) and As(III), which contribute to the formation of Cd-O, Fe-O-Cd, As-O, Fe-O-As, ternary complex Cd-Fe-As, and stable compounds FeAsO 4 ·2H 2 O and CdS. Therefore, The iron sulfide-based porous biochar can be an efficient and environmentally friendly candidate for the treatment of Cd(II) and As(III) co-polluted irrigation water.
研究领域:
环境科学
·
水处理
·
吸附技术
·
材料科学
·
农业环境保护
✓ 已验证
DOI
Desalination and Water Treatment
·
2024
·
IF 1
Dian Lv
In this paper, air-dried lake sludge was pretreated by ball milling, and then pyrolysed at 600°C to prepare lake sludge-derived ball milling biochar, and Fe 3 O 4 was loaded on lake sludge-derived ball milling biochar by chemical precipitation. Scanning electron microscopy-energy-dispersive X-ray spectroscopy, Fourier-transform infrared spectroscopy, and X-ray diffraction were used to investigate and characterize the adsorbents. The results demonstrated that ball mill pretreatment and Fe 3 O 4 -loaded can effectively increase the content of O-containing groups in the adsorbent. The batch adsorption experiments revealed that Cd(II) removal followed the pseudo-second- order kinetic model and the Langmuir model. Additionally, the Cd(II) maximum adsorption by biochar (BC), MBBC and Fe 3 O 4 @MBBC was 31.33, 47.36 and 92.42 mg/g, respectively. The Cd(II) removal mechanisms were complexation, ion exchange, co-precipitation and electrostatic interaction. The Cd(II) removal efficiency on Fe 3 O 4 @MBBC was maintained at 91.35% after 5 adsorption– desorption experiments, indicating that Fe 3 O 4 @MBBC had the ability to be better applied for the removal of Cd(II)-containing wastewater.
研究领域:
环境科学
·
材料科学
·
水处理技术
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）