COLLOIDS AND SURFACES B-BIOINTERFACES
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2022
·
IF 5.999
Wei Yang,Jianwen Fei,Wei Xu,Hongyan Jiang,Marwan Sakran,Junli Hong,Wanying Zhu,Xuemin Zhou
High plasma urate is closely related to gout, cardiovascular and other diseases. Therefore, monitoring the content of uric acid (UA) in plasma is of great significance for the treatment of gout and the prevention of other related diseases. Herein, a biosensor based on the biomimetic oxidase Fe 3 O 4 nanoparticles (NPs) @MnO 2 nanosheets (Fe 3 O 4 @MnO 2 NS) was constructed for colorimetric determination of UA. MnO 2 NS is an efficient biomimetic oxidase, and we found that the intrinsic oxidase activity of MnO 2 NS doped with Fe 3 O 4 NPs can be significantly enhanced. The chromogenic substrate TMB can be catalyzed by Fe 3 O 4 @MnO 2 NS to generate blue oxidized TMB, and UA can decompose the MnO 2 NS to inhibit the color reaction of TMB selectively, thereby realizing the quantitative detection of UA. In addition, the UA biosensor can perform colorimetric analysis of UA level through three methods: naked eye, smartphone and ultraviolet-visible (UV–vis) spectrophotometer. The linear ranges of UV–vis spectrophotometry and colorimetry with smartphone were 1–70 μM and 200–650 μM, respectively, and the limits of detection (LOD) were 0.27 μM and 21 μM. The analysis results of human plasma samples showed that the method had good selectivity and practicability.
研究领域:
生物传感器
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分析化学
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材料科学
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医学诊断
✓ 已验证
产品关联
DOI
PubMed
高影响因子
MICROCHEMICAL JOURNAL
·
2024
·
IF 4.9
Hong Chen,Junyan Liu,Mengna Wan,Shangyi Zhao,Xiaolong Li,Chuan Liu,Xuanping Zhao,Junjie Li,Qingzhen Ma,Cuixiang Li,Xueqin Wang
Fruit juice is kind of popular beverage food worldwidely, and its total antioxidant capacity (TAC) is generally considered as an important index for people’s rational diet, thus accurate evaluation of its TAC is essential for human health guidance. Herein, we constructed a sensitive Fe 3 O 4 @MnO 2 nanocatalyst that was delicately cored with magnetite nanoparticles (Fe 3 O 4 NPs) and encapsulated with manganese dioxide (MnO 2 ) nanoshells for fast and accurate TAC colorimetric analysis in fruit juice. The data showed the fabricated Fe 3 O 4 @MnO 2 nanocatalysts performed with remarkable oxidase mimetic activities and could catalyze oxidization of colorimetric substrate without additional H 2 O 2 , and the limit of detection (LOD) was about 0.39 μM for ascorbic acid (AA) evaluation. Applied in commercial fruit juice products, the fabricated Fe 3 O 4 @MnO 2 nanocatalysts showed a reliable and visual assessment for the accurate TAC analysis. In addition, the fabricated Fe 3 O 4 @MnO 2 nanocatalysts could be easily recycled due to their intrinsic superparamagnetic property. Together, an intellegent Fe 3 O 4 @MnO 2 nanocatalyst was well developed for visual TAC analysis in fruit juice with convenient applications in future.
研究领域:
纳米技术
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分析化学
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食品科学
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材料科学
✓ 已验证
产品关联
DOI
高影响因子
ADVANCED FUNCTIONAL MATERIALS
·
2025
·
IF 19
Shuaizhou Chen,Xuewu Gao,Renyao Huang,Sha Fang,Xingzheng Peng,Mengke Li,Yi Feng,Xiongwei Qu,Xiaojie Zhang
Manganese-based oxides are promising cathode materials for aqueous zinc ion batteries (AZIBs) due to their high energy density and low cost. However, the cycling stability is severely limited by the sluggish reaction kinetics as well as the manganese dissolution. In this work, two pyridinium ionic porous organic polymers (iPOPs) composite ɛ-MnO 2 cathode materials, CN-POP@MnO 2 and PN-POP@MnO 2 , are prepared by an in situ composite method. The stable skeleton of iPOPs effectively prevents the structural collapse of the cathode. Its ionic sites and rigid network framework work together to disrupt the coordination environment of hydrated zinc ions, accelerating reaction kinetics and reducing cathode polarization. Therefore, the resultant batteries based on CN-POP@MnO 2 and PN-POP@MnO 2 cathodes exhibit excellent electrochemical performance. Especially for PN-POP-based batteries, the specific capacity is maintained at ≈96 mAh g −1 after 1500 cycles at 1 C, and the capacity attenuation rate is 0.017% per cycle.
研究领域:
材料科学
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电化学
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储能
✓ 已验证
产品关联
DOI
高影响因子
BIOSENSORS & BIOELECTRONICS
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2022
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IF 12.545
Yingzhi Zhang,Jiayuan Fan,Jing Zhao,Zhangrun Xu
Exosomes, carrying specific molecular information of their parent cells, have been regarded as a kind of promising noninvasive biomarker for liquid biopsy. Plentiful fluorescence methods have been proposed for exosome assay. However, most of them are dependent on nucleic acid signal amplification strategies, which require complicated sequence design and experimental operation. Herein, a metal-enhanced fluorescence (MEF) biochip based on shell-isolated [email protected] 2 nanoparticle array was designed for simple and sensitive assay of exosomes. The designed method consists of only two parts: signal conversion and MEF amplification. The conversion of exosome signals to DNA signals was realized by means of chain displacement reaction. The subtle conversion effectively averts the effect of steric hindrance on MEF while amplifying the signal easily for the first time. The MEF biochip based on shell-isolated [email protected] 2 nanoparticle array achieves a second signal amplification in a simple way. Profiting from the two signal amplifications, this strategy displays high sensitivity toward exosomes with a detection limit of 4.5 × 10 3 particles μL −1 . Compared with the result without MEF, the sensitivity is enhanced about thirty times. As far as we know, this is the first attempt for exosome assay by using MEF strategy. In addition to the favorable fluorescence enhancement, both shell-isolated [email protected] 2 nanoparticles and [email protected] 2 nanoparticle array show excellent stability in buffer solutions, which is conducive to practical application. Moreover, the proposed method is able to distinguish breast cancer patients from healthy people, showing its potential for exosome-based liquid biopsy.
研究领域:
生物医学工程
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纳米技术
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癌症研究
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分子诊断
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ENVIRONMENTAL RESEARCH
·
2023
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IF 8.3
Fan Wang,Yueying Zheng,Xinggang Wei,Dawei Lan,Jintao Zhu,Yingjie Chen,Ziquan Wo,Tao Wu
This study designed a composite material with internal synergistic effects among multiple components to achieve highly selective adsorption of Cu (II). Through controlled synthesis, the Fe 3 O 4 /MnO 2 (3 1 0)/ZIF-67 composite was successfully fabricated, leading to significant improvement in adsorption selectivity , capacity, and adsorption rate. The experimental results showed that the composite is of outstanding selectivity in the adsorption of Cu (II), with a partition coefficient K of Cu (II) that was 2.2–5.3 times higher than that of other coexisting ions. Moreover, the composite exhibited a remarkable adsorption capacity of 1261.0 mg g −1 and a fast adsorption rate of 840.7 mg g −1 h −1 at 298 K. Additionally, its magnetic property facilitated easy separation from wastewater, thereby enhancing its potential for commercial applications. The synergetic effect mechanism was analyzed through characterizations and DFT calculations. Furthermore, the recyclability of the composite was investigated, which showed that after seven cycles, the adsorption efficiency remained at 85% of its initial efficiency. It can be concluded that Fe 3 O 4 /MnO 2 (3 1 0)/ZIF-67 has potential to address challenges posed by heavy metal pollution in copperplating effluents.
研究领域:
环境科学
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材料科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Journal of the Taiwan Institute of Chemical Engineers
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2023
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IF 5.7
Dewei Wang,Zhaorui Sun,Xinliang Han
Background Aqueous non-metallic ammonium ions (NH 4 + ) have newly been developed as a promising charge carrier for electrochemical energy storage owing to their high safety, abundance, and tiny hydrated ionic size. Producing reliable electrode materials with excellent electrochemical performance, however, remains a significant issue. Methods we proposed a bidirectional chemical activation strategy, which effective coupling “in to out” and “out to in” etching manner, to synthesize foam-like porous carbon nanosheets (FCNSs) with the surface area much larger than that samples obtained from the unidirectional mode. Meanwhile, oxygen-deficient α‐MnO 2 nanorods can be rationally obtained through mild redox reaction, both of which display excellent capacitive performance in dilute (NH 4 ) 2 SO 4 electrolyte (0.5 M). Significant findings the as-synthesized FCNSs and oxygen-deficient α‐MnO 2 nanorods can deliver a specific capacitance of 257.5 F g −1 and 525.1 F g −1 , respectively, demonstrating their huge potential to assemble ammonium-ion hybrid supercapacitor (A-HSC). Benefitting from the feasible electrochemical performance for both anode and cathode, the resulting A-HSC displays a specific capacitance of 180.8 F g −1 (calculated based on both anode and cathode) within 0–1.6 V, and a low self-discharge rate, which outperforms the state-of-the-art A-HSC devices. Importantly, the energy storage mechanism has been elucidated from several ex-situ characterizations.
研究领域:
材料科学
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电化学
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能源存储
✓ 已验证
DOI
高影响因子
JOURNAL OF HAZARDOUS MATERIALS
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2017
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IF 6.065
Zhuoyan He,Dehua Xia,Yajing Huang,Xiuqin Tan,Chun He,Lingling Hu,Huanjunwa He,Jiawei Zeng,Wenjun Xu,Dong Shu
A heterogeneous catalytic ozonation/membrane filtration (HCOMF) system was fabricated by integrating a flat-plate polyvinylidene fluoride (PVDF) membrane module along with a slurry catalytic ozonation reactor. The performance and catalytic activity of HCOMF was evaluated for degradation of model wastewater containing bisphenol A (BPA) and humid acid (HA) under different permeation flux in long-term continuous experiments. The membrane fouling was investigated by trans-membranous pressure (TMP), membrane filtration resistance, scanning electronic microscopy (SEM), and fluorescence spectra. The results showed that HCOMF system exhibited an excellent and stable catalytic activity in long-term continuous experiments owning to integration of 3D MnO 2 hollow microsphere ozone-catalysis with flat-plate membrane filtration. The TMP of HCOMF system didn’t increase significantly, and the membrane resistance R p and R c declined from 4% and 16% to 1% and 4%, respectively, thus, the membrane fouling of HCOMF system was mitigated compared to MF system. The mitigation of membrane fouling in HCOMF system was attributed to the increase of hydrophilicity of membrane surface and change of HA fractions.
研究领域:
环境科学
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化学工程
✓ 已验证
DOI
高影响因子
MICROCHIMICA ACTA
·
2021
·Vol. 188
·期 10
·1-10
·
IF 5.833
Xu Shengrui,Dong Panlong,Qin Ming,Liu Hailin,Long Anying,Chen Changpo,Feng Suling,Wu Hongjing
Core-shell structured Fe 2 O 3 /CeO 2 @MnO 2 microspheres were fabricated and used as solid-phase microextraction coating for determination of polycyclic aromatic hydrocarbons (PAHs) in water samples. XPS spectra demonstrated the generation of abundant surface oxygen on Fe 2 O 3 /CeO 2 @MnO 2 microspheres, which provided binding sites for enhancement of analyte extraction. Under optimized conditions, the proposed method presented good linearity in the concentration range 0.04–100 ng mL −1 , with low limits of detection varying from 0.38 to 3.57 ng L −1 for eight PAHs. Relative standard deviations for a single fiber and five batches of fibers were in the ranges of 4.1–8.2% and 7.1–11.4%, respectively. The proposed method was successfully used for determination of PAHs in real river water samples with recoveries ranging from 87.1 to 115.9%. The proposed method using as-prepared Fe 2 O 3 /CeO 2 @MnO 2 microspheres as SPME coating exhibit significant potential for real sample analysis due to its excellent reproducibility, high sensitivity, and good linearity. Graphical abstract
研究领域:
环境科学
·
分析化学
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材料科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Nanoscale
·
2021
·Vol. 13
·期 47
·20205-20212
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IF 7.79
Haifeng Sha,Bing Yan
The wide applications of metal–organic framework (MOF) luminescent materials in the field of optics have attracted the general attention of researchers. Therefore, the development of simple and multifunctional MOF light-emitting platforms have become a research hotspot. The composites (MnO2@ZIF-8-luminol) were prepared by an in situ synthesis method and room-temperature covalent reaction. The composites and o-phenylenediamine (OPD) constitute a dual emission sensor for detecting alanine aminotransferase (ALT). OPD can be oxidized by MnO2 to 2,3-diaminophenazine (DAP) with yellow fluorescence emission, which inhibits the blue emission of luminol through fluorescence resonance energy transfer (FRET). The presence of tiopronin (TP) will destroy the FRET process, extinguishing the yellow fluorescence emission and restoring the blue fluorescence emission. The special effect between ALT and TP will further reverse the changes in the two fluorescent signals. Moreover, in the detection process, when the blue and yellow fluorescence energies in the system are within a certain range, a new white light emission will be generated, which causes the sensing of ALT to present ternary visualization. In addition, a high-security anti-counterfeiting platform is constructed by using the prepared materials and agarose hydrogels. The anti-counterfeiting platform can encrypt information on demand according to the luminous characteristics of different materials. This study not only provides a typical case of ternary visualization sensing by MOF-based materials but also develops a possible method for the construction of a MOF-based hydrogel anti-counterfeiting platform.
研究领域:
生物化学
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材料科学
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医学诊断
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Journal of Materials Chemistry B
·
2018
·Vol. 6
·期 42
·6848-6857
·
IF 4.776
Ying Yang,Chen Wang,Chen Tian,Hailing Guo,Yuhua Shen,Manzhou Zhu
Considering traditional treatment methods, such as chemotherapy, with their potential side effects and lack of targeting, photodynamic therapy (PDT) and photothermal therapy (PTT), being innovative, with less side effects, and light-controlled strategies for antitumour applications, have received extensive attention, but the efficacy of PDT is seriously hindered by the hypoxia tumour microenvironment. Here, a multifunctional nanocomposite composed of an iron oxide (Fe3O4) core and two shells of manganese dioxide (MnO2) and polypyrrole (PPy) was successfully prepared and used to solve these issues. PPy, simultaneously as the photothermal agent and photosensitizer, was first combined with MnO2 to coat magnetic Fe3O4 for achieving an increase in the intracellular O2 concentration and to improve the generation ability of singlet oxygen upon laser irradiation, so that enhanced PDT/PTT could be obtained. After the efficient loading of doxorubicin (DOX) on the Fe3O4@MnO2@PPy nanocomposite, an acid controlled-release behaviour for DOX as well as magnetic-targeting-assisted synergistic effects of chemotherapy and improved PDT/PTT for tumour cells could be realized, which could also protect normal cells from damage. All these features may render our nanocomposite a promising platform to reverse hypoxia-triggered PDT resistance and chemotherapy-caused side effects in cancer therapy and other biomedical applications.
研究领域:
纳米技术
·
癌症治疗
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生物医学工程
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材料科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF MATERIALS SCIENCE
·
2022
·Vol. 57
·期 16
·7909-7922
·
IF 4.682
Chai Chaofan,Yang Xuefang,Yang Xiaohua,Dong Chuan,Bian Wei,Choi Martin M. F.
Abstract The utilization of nanomaterial-based probes in detecting glutathione (GSH) and cell imaging has aroused extensive attention owing to the excellent properties of nanoprobes. Herein, we have synthesized manganese dioxide-S, O co-doped graphitic carbon nitride quantum dots (MnO 2 -S, O-CNQDs) nanocomposite by in situ synthesis of MnO 2 nanosheets in S,O-CNQDs dispersion solution. It was found that GSH could specifically bind to MnO 2 -S, O-CNQDs so that the fluorescence of S, O-CNQDs could be recovered. As such, a “turn-on” MnO 2 -S, O-CNQDs nanoprobe can be fabricated and applied to rapidly determine trace amounts of GSH. Under the optimal conditions, MnO 2 -S, O-CNQDs shows sensitive response to GSH in the range 10–270 μM with a detection limit of 0.307 μM ( S / N = 3). The developed MnO 2 -S, O-CNQDs probe has demonstrated great potential to detection of GSH in biological samples and glutathione injections. What is more, MTT assay indicates that MnO 2 -S, O-CNQDs has low biotoxicity. The non-fluorescence MnO 2 -S, O-CNQDs reacts with GSH to recover the fluorescence of S, O-CNQDs in HepG2 cells. Thus, the “turn-on” fluorescence change of MnO 2 -S, O-CNQDs offers a potentially useful tool to monitor GSH of cancer cells. Graphical Abstract
研究领域:
纳米技术
·
分析化学
·
生物材料
·
细胞生物学
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生物医学工程
✓ 已验证
产品关联
DOI
高影响因子
ACS Sustainable Chemistry & Engineering
·
2017
·
IF 5.951
Weize Yang,Jianzhong Zheng,Shirong Hu,Wuxiang Zhang,Chan Wei,Peihui Dong,Yaru Yan,Haixia Hu
Three-dimensional (3D) Co2(OH)3Cl-MnO2 hybrid sphere was first obtained through a facile solvothermal microwave-assisted synthesis method. Because of the 3D sphere structure with a flowerlike morphology built up by nanosheets, this type of hybrid accelerated ion transfer as well as the charge and simultaneously maximized the electroactivity of Co2(OH)3Cl or MnO2 with a high capacitance of 942.2 F g–1, which was greater than that of the single Co2(OH)3Cl or MnO2. Meanwhile, an asymmetric supercapacitor device was assembled with the hybrid and active carbon (AC) as the positive and negative electrodes, which yielded a specific capacitance of 49.26 F g–1 and a high energy density of 12.62 Wh kg–1 at a power density of 679.10 W kg–1. In addition, the capacitance of this device retained 83.77% after 5000 cycles, which showed a well-defined, long cycle life.
研究领域:
材料科学
·
能源存储技术
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）