ACS Omega
·
2025
·
IF 4.3
Tao Shen,Guodong Wu,Li Yin,Tianen Chen,JiYe Fan,Yuanhao Wang,Shifeng Wang
Developing efficient adsorbents for removal of organic pollutants and heavy metals is essential for environmental protection. In this study, a series of GO/UiO-66-(OH)2 composites were synthesized and characterized using XRD, FT-IR, and SEM, confirming enhanced thermal stability, reduced aggregation, and maintained crystallinity of UiO-66-(OH)2 due to GO incorporation. Batch adsorption experiments showed that GO increased the adsorption capacity, with GO-8/UiO-66-(OH)2 achieving 324.2 mg/g for diclofenac sodium (DCF) and 429.3 mg/g for Hg2+. DCF adsorption was primarily governed by physisorption, while Hg adsorption was chemisorptive, involving strong coordination with oxygen functional groups. Kinetic and isotherm studies revealed the suitability of the pseudo-second-order and Freundlich models, with thermodynamic analysis showing exothermic DCF adsorption and endothermic Hg2+ adsorption. The composites also exhibited high selectivity and stable regeneration, making them promising candidates for practical environmental remediation.
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DOI
PubMed
高影响因子
NEW JOURNAL OF CHEMISTRY
·
2025
·Vol. 49
·期 23
·9663-9668
·
IF 2.5
Wenhui Yao,Yongkui Chen,Xiaowei Guo
With the wide application of gold as a high-value resource, the recycling of gold has received considerable attention. Owing to the functional active sites, tunable pore size and designable structures, metal–organic frameworks (MOFs) have aroused significant curiosity in gold-recycling. However, designing MOFs with both remarkable adsorption capacity and selectivity for Au(III) is highly desirable but challenging. In this work, two hydroxy-modified UiO-66-type MOFs: UiO-66-(OH)2 and UiO-66-OH have been prepared for rapid and selective adsorption of gold ions from aqueous solution. Significantly, UiO-66-(OH)2 was found to exhibit a remarkable gold adsorption capacity of 1570 mg g−1 (pH = 6) compared with UiO-66-OH (520 mg g−1) under uniform conditions. Furthermore, UiO-66-(OH)2 still exhibited excellent gold adsorption efficiency in the presence of other interfering ions. Mechanism analyses revealed that Au(III) was partly transformed to Au(0) by the reducing action of –OH on the framework in the gold adsorption process. Importantly, the MOF materials can be well regenerated by soaking in hydrochloric acid–thiourea aqueous solution.
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SENSORS AND ACTUATORS B-CHEMICAL
·
2019
·
IF 6.393
Liping Du,Wei Chen,Jian Wang,Wen Cai,Shu Kong,Chunsheng Wu
The effective capture and sensitive detection of cancer cells are of great significance to the basic research as well as to the clinical diagnosis and therapy. Here we proposed a simple, low-cost, and high-efficient impedance cytosensor based on folic acid-functionalized zirconium metal-organic frameworks (MOF). Folic acid (FA)-functionalized zirconium MOFs (UiO-66) was utilized as the sensitive element due to the high surface area and porosity, in which FA can be effectively modified onto UiO-66 by the coordinative interaction. The successful preparation of FA@UiO-66 nanocomposite was carefully validated by power X-ray diffraction (XRD), Fourier transform infrared (FT-IR) spectra, UV spectra, zeta potential, transmission electron microscope (TEM), and scanning electron microscope (SEM). The obtained electrochemical impedance results indicated that this impedance sensor functionalized with FA@UiO-66 nanocomposite exhibited good analytical performances in a linear range from 1 × 10 2 to 1 × 10 6 cells/mL. The detection limit was calculated to be as low as 90 cells/mL. It also showed good selectivity in distinguishing FAR-rich cancer cells (e.g. HeLa and H1299 cells) and FAR-negative cells (e.g. HEK-293 cells). HeLa cells spiked in blood samples can also be detected with good recovery rates. All the results demonstrated that this simple and universal approach has great potential to develop disposable and portable biosensors and be applied in the early-stage cancer diagnosis.
研究领域:
生物医学工程
·
分析化学
·
肿瘤学
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RSC Advances
·
2022
·Vol. 12
·期 9
·5062-5071
·
IF 4.036
Zhenshan Li,Qi Li,Rong Jiang,Yan Qin,Yan Luo,Jinsong Li,Wei Kong,Zhiguo Yang,Chao Huang,Xin Qu,Tao Wang,Lin Cui,Gang Wang,Shengchao Yang,Zhiyong Liu,Xuhong Guo
Cu(II) ions are one of the most common forms of copper present in water and can cause bioaccumulation and toxicity in the human body; therefore, sensitive and selective detection methods are required. Herein, a copper ion sensor based on a UiO-66-NH2/ZnO composite material is proposed. The UiO-66-NH2/ZnO nanocomposite was prepared by an ultrasonic mixing method. The morphology and structure of the nanocomposite were studied by scanning electron microscopy (SEM), transmission electron microscopy (TEM) and X-ray diffraction (XRD). The sensitivity to Cu(II) is 6.46 μA μM−1 and the detection limit is 0.01435 μM. The composite material is rich in –OH and –NH2 groups, which are active sites for Cu(II) adsorption. The UiO-66-NH2/ZnO-modified electrode has good repeatability and anti-interference ability. The sensor was successfully used for the determination of Cu(II) in an actual water sample.
研究领域:
环境科学
·
分析化学
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高影响因子
TALANTA
·
2020
·
IF 5.339
Min Wang,Lingyi Zhang,Yameng Zhao,Weibing Zhang
In this study, a new molecularly imprinted material, MIP@UiO-66-NH 2 , was synthesized with glutathione (GSH) as template and mesoporous metal organic framework (UiO-66-NH 2 ) as matrix. The molecularly imprinted polymer was modified on the surface and into the pores of the UiO-66-NH 2 by surface molecular imprinting method with thin polymer layer. Based on high specific surface area (1091.93 m 2 g −1 ) and appropriate pore size (35 nm) of the ordered mesoporous UiO-66-NH 2 , the adsorption capacity for GSH reached 94.43 mg g −1 , and the adsorption equilibrium could be achieved within 30 min. The adsorption isotherm data of MIP@UiO-66-NH 2 could be described well by Freundlich model and the kinetic data complied well with pseudo-second-order model. In addition, the MIP@UiO-66-NH 2 showed low adsorption capacity to GSH structural analogs (Q L-cys = 6.51 mg g −1 ), suggesting great selectivity for GSH recognition. Finally, the MIP@UiO-66-NH 2 was successfully applied for selective separation of GSH from BSA, skim milk and egg white tryptic digest.
研究领域:
分析化学
·
材料科学
·
生物化学
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高影响因子
APPLIED SURFACE SCIENCE
·
2023
·
IF 6.7
Yijun Chen,Meina Cheng,Yundong Wang,Long Jin,Juanhong Li,Hailiang Yang,Sanjian Ma,Guoliang Dai,Zixia Lin,Xin Liu
Both the iron sludge and usage of H 2 O 2 restrict the promotion of the Fenton reaction. Herein, we proposed a hydrogen-accelerated oxygen reduction Fenton reaction system named MHORF-UiO-66(Zr) to try to solve the two problems under normal temperature and pressure. The active hydrogen, which is derived from H 2 catalyzed by the composite of Pd/UiO-66(Zr), could accelerate the reduction of Fe(III) and promote the electron transfer of two-electron oxygen reduction reaction to realize the self-generation of H 2 O 2 . And 45.9 mM of H 2 O 2 could be detected. As expected, 91 % of trimethoprim (TMP) could be degraded within 30 min in this system in the condition of 25 μM Fe(II), H 2 30 mL·min −1 , and Pd/UiO-66(Zr) 2g·L −1 , which was 2.94 times that of the control Fenton system. Based on these results, the feasibility of fundamentally achieving zero emission of iron sludge was successfully verified. It was confirmed that both the hydroxyl radical and singlet oxygen played the dominant roles during the reaction process through the analysis of electron spin resonance spectroscopy. After six reaction cycles, the removal efficiency of TMP could be maintained at least 94 %. It found that both the properties and morphology of this composite could remain based on the systematic characterization.
研究领域:
环境科学
·
化学工程
·
催化材料
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高影响因子
JOURNAL OF CHROMATOGRAPHY A
·
2016
·
IF 3.926
Jia Gao,Chuanhui Huang,Yifen Lin,Ping Tong,Lan Zhang
The present work reported a facile and simple in situ solvothermal growth method for immobilization of metal–organic framework UiO-66 via covalent bonding on amino functional silica fiber for highly sensitive solid-phase microextraction (SPME) of ten polycyclic aromatic hydrocarbons (PAHs) by coupling with gas chromatography–mass spectrometry (GC–MS) analysis. The developed SPME coated fiber has been characterized through SEM, TGA and XRD, confirmed the coating thickness of ∼25 μm with high thermal and chemical stability. Under optimized conditions, the obtained method exhibited satisfactory linearity in range of 1.0–5000.0 ng L −1 for all the PAHs. The low detection limits were from 0.28 ng L −1 to 0.60 ng L −1 (S/N = 3). The UiO-66 coated fibers showed good repeatability (RSDs less than 8.2%, n = 5) and satisfying reproducibility between fiber to fiber (RSDs less than 8.9%, n = 5). This method was successfully used for simultaneous determination of ten PAHs from Minjiang water and soil samples with satisfactory recoveries of 87.0–113.6% and 83.8–116.7%, respectively. Experimental results shows that the chemical bonding approach has dramatically improve the stability and lifetime of pure MOFs coating for SPME in sample pretreatment.
研究领域:
分析化学
·
环境科学
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高影响因子
Frontiers of Chemical Science and Engineering
·
2024
·Vol. 18
·期 11
·1-11
·
IF 4.3
Fu Huiyu,Wu Jiewen,Liang Changhai,Chen Xiao
With the advantages of low raw material cost and 100% atom utilization, the synthesis of high value-added chemical product cyclic carbonates by the cycloaddition of CO 2 to epoxides has become one of the most prospective approaches to achieve the industrial utilization of CO 2 . In the reported catalytic systems, the complexity of the catalyst synthesis process, high cost, separation difficulties, and low CO 2 capture limit the catalytic efficiency and its large-scale application. In this paper, Ag nanoparticles loaded on polyethyleneimine (PEI)-modified UiO-66-NH 2 (Ag/PEI@UiO-66-NH 2 ) are successfully synthesized by in situ immersion reduction. The Ag nanoparticles and the amino groups on the surfaces of PEI@UiO-66-NH 2 contribute to the adsorption of CO 2 and polarization of C–O bonds in epoxides, thereby boosting the conversion capability for the CO 2 cycloaddition reaction. At the amount of propylene oxide of 0.25 mol and the catalyst dosage of 1% of the substrate, the yield and selectivity of propylene carbonate are up to 99%. In addition, the stability and recyclability of Ag/PEI@UiO-66-NH 2 catalyst are attained. The Ag/PEI@UiO-66-NH 2 catalyst also demonstrates a wide range of activity and distinctive selectivity toward cyclo-carbonates in the cycloaddition of CO 2 to epoxides. This work provides a guide to designing a highly efficient catalyst for in situ capture and high-value utilization of CO 2 in industrial applications.
研究领域:
化学工程
·
材料科学
·
催化化学
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高影响因子
Sustainable Materials and Technologies
·
2026
·
IF 9.7
Hong Chen,Wei Ou,Hongchang Huang,Junlan Li,Juncheng Liu
Both the 2D titanium carbide (Ti 3 C 2 T x ) MXene and the 3D rare earth doped zirconium-based metal organic framework (Ln 3+ @UiO-66, MOF) were constructed on the colorless transparent polyimide (CPI) film to form the heterojunction multifunctional nano-coating via a one-pot immersion method in order to improve the UV resistance of CPI. Firstly, the S/CPI film was obtained via the CPI being modified with silica (SiO 2 ) sol, and then the Ti 3 C 2 T x MXene was loaded onto the surface of the S/CPI film via the hydrogen bond, finally the Ln 3+ @UiO-66 was loaded onto the ultra-thin Ti 3 C 2 T x MXene nanosheets to obtain optimal sample (MXene/Ln 3+ @UiO-66-S/CPI). The transmittance of MXene/Ln 3+ @UiO-66-S/CPI is 93.33%, which is only 0.94% lower than that of S/CPI. The tensile strength and elongation of MXene/Ln 3+ @UiO-66-S/CPI are basically the same as those of S/CPI. The attenuation values of transmittance, tensile strength, and elongation for MXene/Ln 3+ @UiO-66-S/CPI film after 5000 equivalent sun hours (ESHs) UV irradiation are 2.44%, 10%, and 18%, respectively, i.e., this film gets both a high transparency and a super ultraviolet resistance. This may be attributed to the fact that the MXene/Ln 3+ @UiO-66 multifunctional nano-coating can absorb the UV light and undergo the down-conversion, weakening the UV irradiation intensity.
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MICROCHEMICAL JOURNAL
·
2026
·
IF 5.2
Guixia Wang,Yao Lei,Liqiang Yang,Zhuo Yang,Ruting Zheng,Xianming Liu,Min Wang
The phosphatase-like activity of UiO-66 was improved by introducing OMS. • UiO-66-OMS exhibited twice the catalytic activity of pristine UiO-66. • This enhanced activity results from enlarged pores and boosted Lewis acidity. • A sensitive colorimetric immunoassay was developed for the detection of CEA. UiO-66 with open metal sites (UiO-66-OMS) nanozymes were synthesized via defect engineering through the introduction of benzoic acid as a modulator during UiO-66 synthesis. As a monocarboxylic acid analogous to the organic ligand 1,4-benzenedicarboxylic acid (BDC), benzoic acid competes with BDC for coordination to Zr O clusters, thereby creating abundant coordinatively unsaturated open metal sites while preserving the crystal structure of UiO-66. Using 4-nitrophenyl phosphate ( p -NPP) as the model colorimetric substrate, UiO-66-OMS exhibited enhanced phosphatase-like catalytic activity, which was twice that of pristine UiO-66. Mechanistic investigations revealed that the increased activity stems from the enlarged pore size and specific surface area of the nanozyme, as well as its enhanced Lewis acidity. By employing UiO-66-OMS as an antibody label, a sensitive colorimetric immunoassay was developed for the detection of carcinoembryonic antigen (CEA), with a linear range of 10–400 ng/mL and a limit of detection of 1.17 ng/mL. This study offers a new strategy for the development of highly active MOF-based nanozymes. Download: Download high-res image (111KB) Download: Download full-size image
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高影响因子
BIOELECTROCHEMISTRY
·
2026
·
IF 4.9
Mingzhu Yang,Dujuan Li,Ao Wang,Yifan Zhang,Jiale Ouyang,Xinyi Wang,Liang Hong,Dingyi Tong,Minghua Wang,Jianhan Lin,Qiong Luo,Gaofeng Wang
Breast cancer, a globally prevalent malignancy in women, requires early diagnosis to improve patient outcomes, where ctDNA serves as a key biomarker. In the present study, an electrochemical biosensor based on CRISPR/Cas12a and Au@UiO-66 nanozyme synergistic dual amplification was developed to achieve ultrasensitive detection of breast cancer marker ctDNA. Au@UiO-66-modified ssDNA probes were anchored to the gold electrode via thiol groups. The intact ssDNA probe anchors Au@UiO-66 nanozyme to the electrode, where its peroxidase-like activity efficiently catalyzes H 2 O 2 reduction to generate amplified reduction peak currents. Target ctDNA activates Cas12a's trans-cleavage capacity by binding specifically to crRNA. Under the presence of the target, Au@UiO-66 nanozymes are released, resulting in a discernible drop in the peak current linked to H 2 O 2 reduction. Benefiting from the optimized experimental conditions, the biosensor demonstrates a broad linear detection range (from 10 fM to 10 nM) for the target ctDNA, along with an exceptionally low detection limit of 6.14 fM. Successful detection in human serum samples demonstrates its practicality. The platform's high specificity is attributed to the programmable crRNA design, enabling detection of specified DNA sequences and showcasing significant adaptability for diagnosing multiple genetic targets, highlighting its potential in clinical cancer diagnosis.
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PubMed
高影响因子
Journal of Environmental Chemical Engineering
·
2026
·
IF 7.5
Shuangshuang Long,Jingwen Wang,Shuqian Meng,Yaxin Liu,Jing Zhang,Zihao Ren,Jiadi Li,Yangyang Xin,Zheng Dong,Baolu Cui,Libing Qian,Wenwu Zhou,Kai Hu,Luyao Wang,Peipei Li,Yaping Zheng,Zhiyuan Yang,Dechao Wang
Porous liquids (PLs), combine the high adsorption capacity of porous solids with the fluidity of liquids, show great promise in selective CO 2 capture. However, current studies on Type I PLs lacks systematic investigations into the regulatory role of porous host particle size and its impact on in-depth analysis of the gas sorption-separation process. Herein, we successfully fabricated PLs by grafting polyether amine oligomer chains onto the surface of size-tailored UiO-66-OH as the porous host, which endow the PLs with good thermal stability, transparency, low viscosity, and promising CO 2 /N 2 separation. UiO-66-OH-PLs were fabricated by grafting polyether amine oligomer steric solvent onto UiO-66-OH via dehydrative condensation. The effect of porous host size on CO 2 separation behavior of UiO-66-OH-PLs and the selective sorption-separation mechanism were systematically investigated using sorption isotherm and kinetic models. UiO-66-OH-PLs exhibit markedly enhanced CO 2 sorption capacity relative to the pure steric solvent, confirming the preservation of accessible cavities in porous hosts. The PLs further exhibit distinct size-dependent physicochemical and sorption properties as decreasing the particle size of UiO-66-OH porous hosts increases oligomer grafting density, reduces bulk viscosity and enhances both CO 2 sorption capacity and CO 2 /N 2 separation selectivity. CO 2 adsorption isotherms are best fitted by the SS-Langmuir-Freundlich model, indicating that CO 2 sorption by UiO-66-OH-PLs is single-component sorption on heterogeneous surfaces, integrating Langmuir monolayer sorption and Freundlich non-ideal sorption characteristics. Kinetic analysis reveals that the optimal pseudo-first-order kinetic model, demonstrating that CO 2 sorption rate is dominated by the sorption-desorption process between adsorbate molecules and adsorbent surface-active sites, rather than intraparticle or liquid film diffusion. This work opens up a promising avenue for the rational design of high-performance PLs that can be tailored to meet the demands of practical industrial chemical separation processes.
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