MICROCHEMICAL JOURNAL
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2025
·
IF 5.1
Fulin Yang,Hongjie Liu,Hao Fu,Chaoxin Zhang,Changrui Ye,Shaopeng Wang,Man Zhang,Fang Shen,Liwei Wang
As one of the significant algal bloom species, Akashiwo sanguinea has long brought challenges to controlling red tide. Red tide outbreaks are often accompanied by the mass propagation of various algal bloom species, which brings problems to investigating red tides using traditional optical methods. Electrochemical biosensing technology has high sensitivity and specificity, yet its use in detecting A. sanguinea DNA in sea areas is insufficient. Here, the amplification system combining Nt.BbvCI endonuclease-assisted and hybridization chain reaction (HCR) has a detection limit of the same or even lower magnitude than other HCR systems. More importantly, the auxiliary short strands from the Nt.BbvCI system activates HCR, reducing the steric hindrance of long DNA molecules and enhancing HCR’s activity. Thus, the portable electrochemical biosensor based on this system successfully detected simulated A. sanguinea DNA samples, with a limit of detection (LOD) at 1.53 fg/μL and a limit of quantification (LOQ) at 4.27 fg/μL, far better than traditional optical-based methods. Also, the predicted cell density of A. sanguinea generally matches that of optical microscopy. This portable biosensor is expected to conduct an on-site investigation of A. sanguinea ’s cell density. It can provide data support for early warnings of red tide outbreaks and reduce the time needed for investigations.
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JOURNAL OF ALLOYS AND COMPOUNDS
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2025
·
IF 6.3
Jianyan Ding,Dewu Wu,Shanshan Ye,Quansheng Wu
The advancement of narrow-band cyan-emitting phosphors activated by near-ultraviolet LED chips is crucial for creating high-efficiency, health-promoting WLED lighting. Guided by a single and symmetrical crystallographic site, a near-ultraviolet excitation, near-narrow-band, and thermally stable cyan light emission was achieved from Bi 3+ -activated garnet-structured Ca 3 Xn 2 Ge 3 O 12 :Bi 3+ (Xn = Sc, Y, Lu). When incorporated into WLEDs, the color rendering index (CRI) of devices containing Ca 3 Sc 2 Ge 3 O 12 :Bi 3+ cyan phosphor reaches 92.8, indicating potential value for healthy lighting applications. Furthermore, by integrating spectral and crystallographic data with empirical formula calculations, a comprehensive analysis of the luminescence behavior among the three Ca 3 Xn 2 Ge 3 O 12 :Bi 3+ (Xn = Sc, Y, Lu) phosphors were performed. This analysis was designed to elucidate the similarities and differences in their luminescence properties, as well as to uncover the underlying mechanisms responsible for the near-narrow-band emission of Bi 3+ . The results indicate that under the combined influence of factors volume polarization, fractional covalency, and charge of the anions, Ca 3 Xn 2 Ge 3 O 12 :Bi 3+ (Xn = Sc, Y, Lu) exhibits the same strongest excitation peak. However, due to variations in Stokes shift and bandgap, the three phosphors exhibit distinct emission peaks and thermal quenching properties. This study aims to establish fundamental principles for the development of Bi³ ⁺-activated narrow-band emission phosphors.
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JOURNAL OF SOLID STATE ELECTROCHEMISTRY
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2025
·
IF 2.6
Cao Bo-Qun,Bao Hao-Tian,Zhang Ji-Wei,Shao Gang-Qin
The lithium-phosphorus-thiohalides (LPS X ) with superionic conduction are strong candidates for the new-generation solid electrolytes (SEs) in all-solid-state lithium-ion batteries (ASSLIBs). In this work, Li 6− x PS 5− x Cl 1+ x − y Br y (LPSCB; 0 ≤ x ≤ 0.7; 0 ≤ y ≤ 1.7) was synthesized by a solid-state method in which the key raw material of Li 2 S was prepared by an improved carbothermal reduction method without late decarbonization. The lattice flexibility and the degree of structural order are opposite effect and would lead to an optimum of the ionic conductivity at a composition of LPSCB. Li 6 PS 5 Br- and Li 5.5 PS 4.5 Br 1.5 -based ASSLIBs had the best rate capacity and cycle performance in Li 6 PS 5 Cl 1− y Br y - (0 ≤ y ≤ 1) and Li 5.5 PS 4.5 Cl 1.5− y Br y -based ones (0 ≤ y ≤ 1.5), respectively. To increase the ionic conductivity of LPSCB-type SEs and capacity/cycle performance of the related ASSLIBs, Br-introduction, mutual substitution and excess- X substitution were extremely effective strategies. Graphical
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MICROCHEMICAL JOURNAL
·
2026
·
IF 5.2
Junyi Wu,Yao Liu,Dongwei Zhu,Jianxing Xu,Jian Yun
A DSN-triggered Y-shaped dual-circular-probe DNA walker is developed for RCI-associated miR-29a detection. • The Y-shaped steric hindrance structure effectively suppresses non-specific DSN cleavage, ensuring ultralow background. • The cascade amplification strategy achieves a detection limit as low as 0.26 fM for miR-29a. • The ICP-MS-based Rh readout provides label-free, photobleaching-free, and robust quantification. • The method exhibits excellent single-base mismatch discrimination and reliable performance in serum and cell samples. Rotator cuff injury (RCI) is a prevalent musculoskeletal disorder with limited early diagnostic options, partly due to the lack of sensitive and non-invasive biomarkers. Magnetic resonance imaging (MRI), the current mainstream imaging tool for RCI, suffers from high cost, limited accessibility, and an inability to reflect molecular-level pathological changes before structural damage becomes evident. MicroRNAs (miRNAs) have shown promise as diagnostic indicators, yet their reliable detection in clinical contexts requires methods with ultrahigh sensitivity and single-base resolution. Here, we report a duplex-specific nuclease (DSN)-triggered DNA walker with dual circular probes for highly specific and ultrasensitive analysis of RCI-associated miR-29a by inductively coupled plasma mass spectrometry (ICP-MS). The DNA walker is assembled on magnetic beads, where the walking track comprises two circular probes (c1 and c2) forming a Y-shaped steric hindrance structure that effectively suppresses non-specific DSN cleavage, ensuring an ultralow background. Upon target miR-29a hybridization, DSN specifically cleaves the DNA–RNA hybrid, initiating a cascade amplification involving self-priming, nicking/polymerase cycling, rolling circle amplification, and DNAzyme-mediated cleavage of a rhodium-labeled substrate. The released rhodium is quantified by ICP-MS, providing a photobleaching-free readout. The proposed method achieves a detection limit as low as 0.26 fM with outstanding single-base mismatch discrimination, a wide dynamic range from 1 fM to 100 pM, excellent recoveries in serum (93.2–103.2%), and high correlation with RT-PCR (R 2 = 0.9912) in real cell line samples. This DSN-triggered DNA walker offers a robust, sensitive, and specific platform for RCI-related miRNA detection, holding great promise for early diagnosis and prognosis monitoring of rotator cuff injuries. Download: Download high-res image (78KB) Download: Download full-size image
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AIP Advances
·
2022
·Vol. 12
·期 5
·
IF 1.697
Tu Huan,Zhao Guoying,Hou Jingshan,Liu Yufeng,Zhou Yan,Zhang Ganghua,Sun Hong-Tao,Li Ji-Guang,Fang Yongzheng
White light emitting diodes (LEDs) suffer from two most common drawbacks: the deficiency of the red component and the poor thermal stability of silicone. Ce 3+ -doped garnet phosphors with tailor-made luminescence properties can be achieved by variations in {A}, {B}, and {C} cation sites. Herein, a simultaneous ion co-substitution design strategy has been adopted to synthesize a series of (Y, Ca) 3 (Al, Mg) 2 (Al, Si) 3 O 12 garnet phosphors and corresponding phosphor-in-glass (PiG) films. The co-substitution is finely restricted to the assigned sites. The emission peak is shifted from 529 to 565 nm, which is beneficial to obtain low color temperatures and high color rendering using a single phosphor for white LEDs. By employing the as-synthesized phosphor, the corresponding PiG films were fabricated by the low temperature co-sintering technology using the SiO 2 –B 2 O 3 –ZnO–Na 2 O glass system characterized with excellent thermal stability and moisture resistance. The morphological and elemental analyses demonstrated that the as-made phosphor powders were uniformly distributed in the glass host without any interfacial reactions. Finally, modular white LEDs with a high color rendering (Ra = 82.7) is achieved through the as-synthesized PiG film on an InGaN blue chip. This study may open up a facile approach to obtain high quality luminescence based on the mono-luminescence center, avoiding excitation energy wastage and low quantum efficiency aroused by multi-luminescence centers or color compensation phosphors in glass.
研究领域:
材料科学
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光电子学
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固态照明
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无机化学
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应用物理学
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Journal of Chemistry
·
2021
·Vol. 2021
·期 1
·5556295
·
IF 2.506
Zongqiang Zhu,Hongqu Yang,Jie Liu,Yinian Zhu,Shen Tang,Lihao Zhang,Xingxing Wang
Basic ferric sulfate-arsenates [FeSAsOH, Fe(SO 4 ) x (AsO 4 ) y (OH) z ·nH 2 O] were prepared and characterized to study their potential fixation of arsenic in the oxidizing and acidic environment through a dissolution for 330d. The synthetic solids were well-shaped monoclinic prismatic crystals. For the dissolution of the sample FeSAsOH–1 [Fe(SO 4 ) 0.27 (AsO 4 ) 0.73 (OH) 0.27 ·0.26H 2 O] at 25–45°C and initial pH 2, all constituents preferred to be dissolved in the order of AsO 4 3− > SO 4 2− > Fe 3+ in 1–3 h, in the order of SO 4 2− > AsO 4 3− > Fe 3+ from 1–3 h to 12–24 h, and finally in the order of SO 4 2− > Fe 3+ > AsO 4 3− . The released iron, sulfate, and arsenate existed dominantly as Fe 3+ /Fe(OH) 2+ /FeSO 4 + , HSO 4 − /SO 4 2− /FeSO 4 + , and H 3 AsO 4 0 /H 2 AsO 4 − , respectively. The higher initial pHs (6 and 10) could obviously inhibit the release of Fe 3+ from solid into solution, and the solid components were released in the order of SO 4 2− > AsO 4 3− > Fe 3+ . The crystal tops were first dissolved, and the crystal surfaces were gradually smoothed/rounded until all edges and corners disappeared. The dissociations were restricted by the Fe-O(H) breakdown in the FeO 6 octahedra and obstructed by the OH − and AsO 4 tetrahedra outliers; the lowest concentration of the dissolved arsenic was 0.045 mg/L. Based on the dissolution experiment at 25°C and pH 2, the solubility products ( K sp ) for the basic ferric sulfate-arsenate [Fe(SO 4 ) 0.27 (AsO 4 ) 0.73 (OH) 0.27 ·0.26H 2 O], which are equal to the ion activity products (logˍIAP) at equilibrium, were calculated to be -23.04 ± 0.01 with the resulting Gibbs free energies of formation (Δ G f o ) of −914.06 ± 0.03 kJ/mol.
研究领域:
化学
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环境科学
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NEW JOURNAL OF CHEMISTRY
·
2017
·Vol. 41
·期 7
·2793-2799
·
IF 3.269
Guangyin Fan,Xiaojing Li,Yuling Ma,Yun Zhang,Jiangtao Wu,Bin Xu,Ting Sun,Daojiang Gao,Jian Bi
Exploring the applications of two dimensional layered Ti3C2X2 (X = OH, F) is of great importance because of its excellent physical and chemical properties. Herein, we report the synthesis of the bimetallic catalyst PtyCo1−y/Ti3C2X2via a facile one-pot approach using Ti3C2X2 as the support. The in situ synthesized PtyCo1−y/Ti3C2X2 is subsequently applied as a catalyst for hydrogen evolution from the hydrolysis of ammonia borane at 25 °C. Experimental results show that Pt0.08Co0.92/Ti3C2X2 exhibits excellent catalytic activity for the hydrolysis of ammonia borane with a high hydrogen generation rate of 100.7 L H2 (min gPt)−1 and turnover frequency of 727 mol H2 (min molPt)−1 because of the synergistic effect between Pt and Co. Moreover, Pt0.08Co0.92/Ti3C2X2 could be recovered from the reaction mixture by a magnet and recycled at least seven times, thus showing its high recycling efficiency.
研究领域:
材料化学
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催化化学
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纳米材料
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能源化学
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物理化学
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MOLECULES
·
2023
·Vol. 28
·期 5
·2149
·
IF 4.6
Zhe Chen,Zhuoyi Wang,Yihua Yuan,Bo Liu,Jiangbo Yu,Zhiwen Wei,Keming Yun
DNA self-assembled fluorescent nanoprobes have been developed for bio-imaging owing to their high resistance to enzyme degradation and great cellular uptake capacity. In this work, we designed a new Y-shaped DNA fluorescent nanoprobe (YFNP) with aggregation-induced emission (AIE) characteristic for microRNA imaging in living cells. With the modification of the AIE dye, the constructed YFNP had a relatively low background fluorescence. However, the YFNP could emit a strong fluorescence due to the generation of microRNA-triggered AIE effect in the presence of target microRNA. Based on the proposed target-triggered emission enhancement strategy, microRNA-21 was detected sensitively and specifically with a detection limit of 122.8 pM. The designed YFNP showed higher bio-stability and cell uptake than the single-stranded DNA fluorescent probe, which has been successfully applied for microRNA imaging in living cells. More importantly, the microRNA-triggered dendrimer structure could be formed after the recognition of target microRNA, achieving a reliable microRNA imaging with a high spatiotemporal resolution. We expect that the proposed YFNP will become a promising candidate for bio-sensing and bio-imaging.Keywords:DNA fluorescent nanoprobes;Y-shaped;aggregation-induced emission;microRNA;live-cell imaging
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高影响因子
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
·
2026
·
IF 9.2
Dong-Chu Lu,Juan Xie,Yuan Gao,Cheng-Xin Li,Shan-Lin Zhang
The TEC of BFZYZ is lower to 13.8 × 10 −6 1/K, matching well with the electrolyte. • Y and Zn co-doping enhances hydration ability and surface oxygen vacancies. • BFZYZ yields an R p of 0.26 Ω cm 2 at 600 °C, 50% lower than that of BFZ. • PCFC with BFZYZ electrode achieved peak power density of 0.8 W/cm 2 at 600 °C. • The cell with BFZYZ electrode operates stably for 500 h. Developing active and durable oxygen electrodes for both oxygen reduction and oxygen evolution reactions at low temperatures remains a major challenge for proton ceramic electrochemical cells (PCECs). Herein, a cobalt-free Y and Zn co-doped Ba(Fe,Zr)O 3−δ perovskite (BFZYZ) is developed as a PCEC oxygen electrode, integrating excellent electrochemical performance and durability. At 600 °C, Y and Zn co-doping reduces the polarization resistance by 50%, mainly owing to enhanced hydration capability and surface oxygen exchange, which accelerate ORR/OER kinetics. Meanwhile, BFZYZ shows a lower average thermal expansion coefficient of 13.8 × 10 −6 1/K over 30–600 °C, improving its thermal compatibility with the electrolyte. The PCEC with BFZYZ electrode achieves a peak power density of 0.8 W/cm 2 in fuel cell mode and a current density of 0.82 A/cm 2 at 1.3 V in steam electrolysis mode at 600 °C, with stable operation, demonstrating the potential of BFZYZ for high-performance and durable PCECs.
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ANALYTICA CHIMICA ACTA
·
2017
·
IF 4.95
Meng Chen,Ning Gan,Tianhua Li,Ye Wang,Qing Xu,Yinji Chen
An effective electrochemical aptasensor has been developed for the detection of multiplex antibiotics using Y-shaped DNA probes . These probes-based metal ions encoded the nanoscale metal-organic frameworks (NMOF) as a substrate, and circular strand-replacement DNA polymerization (CSRP) target triggered the amplification strategy. The Y-DNA probes (Y-DNA) were assembled using an assisted DNA probe (assisted DNA labeled with magnetic gold nanoparticles) which can hybridize to the captured DNA probe (consisting of aptamer and primer recognition region), and signal tags (NMOF encapsulating signal DNAs and different metal ions such as Pb 2+ or Cd 2+ ). Notably, NMOF was employed as the developed platform with a large specific area to load abundant metal ions that can produce distinguishable signals. In the presence of targets, chloramphenicol (CAP) and oxytetracycline (OTC) as models, the conformational change of the captured DNA can disassemble the Y-DNA probes that can consequently release the signal tags in the supernatant due to the high affinity of targets towards the aptamer domain than its complementary sequences. Subsequently, the exposed sequences of captured DNA serve as the initiators for triggering the target cyclic-induced polymerization with the assistance of Bst DNA polymerase. Thus, numerous signal tags could be detected by square wave voltammetry in the supernatant after magnetic separation, thereby amplifying the electrochemical signals. The proposed strategy exhibited a high sensitivity to antibiotics with a detection limit of 33 and 48 fM (S/N = 3) towards CAP and OTC, respectively. Moreover, this aptasensor showed promising applications for the detection of other analytes.
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Food Bioscience
·
2025
·
IF 5.9
Lijun Ling,Fanjin Kong,Yijuan Jiang,Wenyue Zhang,Rongxiu Mo,Rui Yue,Yao Li,Lijun Feng,Yongpeng Zhou
Citrus reticulata 'Shiyue Ju' are prone to fungal infections because of their high maturity, water content, and remote cultivation locations. Chemical control, though effective, leaves fruit residues that endanger health and the environment. Endophytic VOCs potently inhibit pathogens with high efficacy, low cost, and minimal ecological impact, positioning them as promising natural post-harvest preservatives. In this study, we isolated the pathogenic fungus ( Penicillium italicum Q-1) from rotting Citrus reticulata 'Shiyue Ju' and used Q-1 as the test strain to screen for endophytic fungi Y-4 isolated from healthy Citrus reticulata 'Shiyue Ju' that can produce VOCs with strong antagonistic activity. We analyzed the VOC components and screened for the highly bactericidal activity compound 3-pentene-2-one,exhibiting complete (100 %) growth inhibition at 4 μL/L. We also investigated the inhibitory activity and mechanisms of action of the VOCs and antifungal compounds. The results indicated that the VOCs produced by Y-4 and 3-pentene-2-one could inhibit the growth and reproduction of the pathogenic fungus, primarily by disrupting the normal morphological structure of hyphae and spores and damaging the integrity of the cell membrane. Furthermore, 3-pentene-2-one at appropriate concentrations can inhibit the spread of pathogenic fungi on Citrus reticulata 'Shiyue Ju' and effectively delay the decline in fruit quality. These findings indicate that 3-pentene-2-one is a powerful tool for controlling P. italicum and provides a theoretical basis for post-harvest disease management of Citrus reticulata 'Shiyue Ju' .
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Materials
·
2023
·Vol. 16
·期 20
·6667
·
IF 3.4
Yukun Li,Svenja Hanson,Cheng Heng Pang,Peng Lyu,Jun Jiang
In order to attain phosphor ceramics with a high Color-Rendering Index (CRI), samples with the composition of Y0.997−xRexCe0.003)3(Al0.9748Mn2+0.024Cr3+0.0012)5O12(Rex= 0, Gd0.333, Gd0.666, Gd0.997, Tb0.333, Tb0.666, Tb0.997and Lu0.997were prepared by solid-state reaction and vacuum sintering, and exhibited potential for high-quality, solid-state lighting. Doping with Cr3+and Mn2+effectively enhanced the red component of Ce3+spectra through the intense energy transfer from Ce3+ions to Mn2+/Cr3+ions. The crystal field splitting of [GdO8] and [TbO8] was more extensive than that of [YO8], causing a massive redshift in the Ce3+emission peaks from 542 to 561 and 595 nm, while [LuO8] had an opposite effect and caused a blueshift with a peak position at 512 nm. White LED devices incorporating Ce/Mn/Cr: (Gd0.333Y0.664)3Al5O12phosphor ceramic exhibited a high CRI of 83.97, highlighting the potential for enhancing the red-light component of white LED lighting.Keywords:garnet phosphor;laser lighting;full spectrum;spectral modulation;Ce/Mn/Cr: (Re,Y)3Al5O12
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