Green Energy & Environment
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2026
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IF 16.7
Zhen Zhang,Kang Zhou,Xinru Zhao,Armin Rezayan,Dan Wu,Qianli Ma,Zongwu Zhang,Jianshe Wang,Xinqing Chen,Chunbao Xu,Yongsheng Zhang
Water can dissociate on the CoP shell with the formation of H - -Co δ+ -P-O-H + intimate metal-acid sites. • Intimate metal-acid bifunctional sites effectively catalyze the hydrodeoxygenation of furfural to 2-methylfuan. • Brønsted acid sites promote hydrolysis and ring-opening hydrogenolysis of 2-methylfuran to yield 1,4-pentanediol. • Co@CoP catalyst exhibits excellent stability and high activity for the hydrodeoxygenation of various biomass-derived feedstocks. Transition metal phosphides represent promising metal-acid bifunctional catalysts for hydrogenation reactions. However, the origin of the acidity of metal phosphides and their synergistic effects with metallic sites remain poorly understood. Herein, a highly efficient core-shell Co@CoP catalyst prepared via controlled phosphidation of cobalt carbonate was developed for the one-pot transformation of furfural to 1,4-pentanediol. The metallic Co core accelerates active hydrogen transfer, while the CoP shell enables water dissociation to form intimate H - –Co δ+ –P–O–H + metal-acid sites. While the metal-acid bifunctional sites synergistically catalyze the efficient hydrodeoxygenation of furfural to 2-methylfuran intermediate, the Brønsted acid sites on CoP further selectively activate the C–O–C bond of 2-methylfuran, facilitating hydrolysis and ring-opening hydrogenolysis. A 1,4-pentanediol yield of 92.2% is achieved under mild conditions, with excellent cycling stability and applicability for various biomass-derived feedstocks. The disclosed water-engineered Brønsted acidity over metal phosphides provides a fundamental basis for the rational design of bifunctional catalysts for biomass valorization. Co@CoP catalyst enables water dissociation to form intimate H - –Co δ+ –P–O–H + metal-acid sites. While the metal-acid bifunctional sites synergistically catalyze the efficient hydrodeoxygenation of furfural to 2-methylfuran intermediate, the Brønsted acid sites on CoP further selectively activate the 2-methylfuran, facilitating hydrolysis and ring-opening hydrogenolysis. Download: Download high-res image (277KB) Download: Download full-size image
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高影响因子
JOURNAL OF CATALYSIS
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2026
·
IF 6
Xiang Li,Wei Li,Ling Wang,Siqi Xu,Tete Xie,Xiu Xiu Zou,Peng Wang,Peng Huang,Shangxing Chen,Zongde Wang,Wenyuan Han,Aliaksandr Tsyhanau,Qiang Deng
Developing a cost-effective catalyst for the selective tandem conversion of furfural (FFA) to ethyl levulinate (EL) is important for synthesizing biofuels and fine chemicals from biomass. However, traditional catalysts prefer the hydrogenation-dehydration-hydrolysis pathway and are slow due to high activation energy requirement. Herein, a NiCoP/LaPO 4 catalyst was prepared via calcination of layered double hydroxide (LDH) precursor, followed by hydrogen reduction, and phosphating. When applied to the tandem of FFA for EL production, it exhibited a high selectivity of 90.1% at 160 °C under ethanol and water via acetalization–hydrogenolysis–hydrolysis route. Catalytic mechanism investigation indicated that in situ hydrogen spillover from NiCoP nanoparticles to the LaPO 4 support, leading to the formation of H + –H − pairs. These H + –H − pairs not only provide Brønsted acid sites to drive FFA acetalization and 2-ethoxymethyl furan (EMF) hydrolysis but also activate the C–O bonds of the key intermediate 2-diethoxymethyl furan (DEMF) via the S N 2 mechanism, markedly accelerating the hydrogenolysis step. Moreover, the NiCoP/LaPO 4 catalyst shows remarkable catalytic versatility for the synthesis of different alkyl levulinates from a range of alcohols (i.e., methanol, propanol, isopropanol, butanol and benzyl alcohol). This study presents an efficient bifunctional catalysis approach for complex tandem reaction pathways aimed at synthesizing alkyl levulinate by hydrogen spillover to generate transient H + –H − pairs.
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Current Research in Food Science
·
2026
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IF 7.7
Xingyi Jiang,Yanbo Luo,Xiangyu Li,Hongfei Zhang,Fengpeng Zhu,Yuwei Liu,Yongqiang Pang,Di Chen
Furfural compounds are important markers of thermal processing in foods and herbal products. However, their analysis in complex samples presents substantial challenges due to matrix interferences and limited detectability. This study introduces a multi-functional magnetic adsorbent synthesized via one-pot grinding, integrating pH adjustment, derivatization, and extraction into a single step. The adsorbent releases citric acid and 2,4-dinitrophenylhydrazine upon dispersion, leading to a pH decrease (∼2.5) and a light-yellow color change, which confirms the initiation of pH adjustment and derivatization. Meanwhile, magnetite nanoparticles (Fe 3 O 4 ) and hydroxylated multi-walled carbon nanotubes self-assemble to extract analytes. Combined with liquid chromatography–ultraviolet analysis, the method achieved satisfactory linearity (0.05–5 μg/mL, R 2 > 0.992), low limits of detection (8.0–13.7 ng/mL), and high recoveries (87.7–99.4%) with relative standard deviations ≤12.1%. It was successfully applied to diverse samples, including teas, juices, coffees, and herbal liquids. Optimization confirmed a 50% ethanol content, a 3 mL sample volume, and 30 min incubation at 30 °C. This strategy integrates derivatization, pH adjustment, and extraction into a self-activated platform suitable for automated operation. It simplifies workflows, improves reproducibility, and shows strong potential for high-throughput food safety and quality monitoring.
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PubMed
高影响因子
ACS Sustainable Chemistry & Engineering
·
2022
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IF 9.224
Hengyu Hao,Yuya Abe,Haixin Guo,Xiao Zhang,Richard Lee Smith Jr
Bifunctional Lewis (L) acid (Ni- or Hf-) site–Brønsted (B) acid catalysts designed to promote transfer hydrogenation reactions were prepared via hydrothermal and solvothermal methods using safe mixed solvents and sustainable precursors. By using N,N-dimethylformamide as a basis for the desired basicity, mixed solvents could be identified that allowed catalysts to be prepared with tunable ratios of Lewis to Brønsted acid sites (L/B). The as-prepared catalysts promoted transfer hydrogenation of furfural and ethanolysis to form ethyl levulinate (EL) using ethanol as a solvent and hydrogen donor source. Among the catalysts, sulfonated Hf-catalysts prepared with a cyclopentanone/formic acid mixed solvent (Hf-CPN/FA) with an L/B ratio of 6.4 gave 95% furfural conversion with 51.9% yield of EL, while the sulfonated Hf catalyst prepared with a cyclopentanone/γ-valerolactone mixed solvent (Hf-CPN/GVL) with a total Lewis and Brønsted acid site amount of 85.1 μmol/g gave 100% furfuryl alcohol (FAL) conversion with 72.5% yield of EL. Brønsted acid sites promoted reversible acetalization of furfural with ethanol into 2-furaldehyde diethyl acetal, while Lewis acid sites promoted furfural transfer hydrogenation into FAL and EL and further conversion into γ-valerolactone. The methods developed in this work eliminate dipolar aprotic solvents and harsh acids used in catalyst synthesis and allow sustainable production of EL from biomass-related chemicals.
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高影响因子
Frontiers in Pharmacology
·
2022
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IF 5.988
Zhang Wensen,Cui Na,Su Fazhi,Wang Yangyang,Yang Bingyou,Sun Yanping,Guan Wei,Kuang Haixue,Wang Qiuhong
Radix Rehmanniae (RR, from Radix Rehmanniae (Gaertn.) DC.) is a natural medicine used in traditional Chinese medicine (TCM) since ancient times for the treatment of blood disorders. RR is steamed to get Rehmanniae Radix Praeparata (RP), which has a tonic effect on blood; the content of 5-hydromethylfurfural (5-HMF) increases more than four times after steaming. Studies have shown that 5-HMF has positive pharmacological effects on cardiovascular and hematological disorders. This study aimed to explore and verify the impact of 5-HMF on rats with chemotherapy-induced blood deficiency syndrome (BDS). Rats were given cyclophosphamide (CP) and acetophenhydrazine (APH) to induce BDS, the coefficients of some organs (liver, spleen, and kidney) were measured, and a routine blood test examined the coefficients of several peripheral blood cells. Metabolomics and network pharmacology were combined to find important biomarkers, targets, and pathways. Western blot was used to detect the expression of CYP17A1 and HSD3B1 proteins in the spleen. All these findings suggested that the 5-HMF significantly increased the number of peripheral blood cells and reversed splenomegaly in rats. In addition, 5-HMF upregulated CYP17A1 and HSD3B1 protein expression in splenic tissues. Also, 5-HMF ameliorated chemotherapy-induced BDS in rats, and its therapeutic mechanism might depend on steroid hormone biosynthesis and other pathways. It acts on blood deficiency via multiple targets and pathways, which is unique to Chinese medicine.
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PubMed
高影响因子
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
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2022
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IF 4.831
Fu Wan,Yu Lei,Changding Wang,Xinyuan Zhang,Honglin He,Lei Jia,Tingting Wang,Weigen Chen
Accurately evaluating the aging state of oil paper insulation in electrical equipment is a key to ensure the safe operation of the power transformer. For achieving highly sensitive in-situ detection of dissolved furfural in transformer oil with good reproducibility, flower-like silver nanoparticles modified with carbon nanotubes (CNTs@Ag-F-AgNPs) was synthesized by a combination of electroless silver plating and redox method. The large specific surface area and strong adsorption capacity of CNTs@Ag promoted the formation of more “hot spots”. CNTs@Ag-F-AgNPs were adsorbed on Si-Au substrate via mercapto groups on the coupling agent 1′4 phenyldimercaptan molecule (BDT). Using rhodamine 6G (R6G) as probe molecule, the enhanced factor reached 6.96 × 10 9 . Then, the substrate was used for in-situ SERS detection of transformer oil-dissolved furfural at different concentrations and the detection limit was 2.25 mg/L at 1703 cm −1 (Stretching vibration of C = O in furfural molecule), fulfilling requirements of furfural content detection after severe aging of transformer (4 mg/L). Besides, the relative standard deviation (RSD) of characteristic peak intensity at ten different positions was only 1.74%. These results exhibite that three-dimensional nanostructure with high sensitivity and good reproducibility exhibited a wide application range for in situ detection of dissolved trace furfural in transformer oil.
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高影响因子
BIORESOURCE TECHNOLOGY
·
2022
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IF 11.889
Li-Li Sun,Zhuang Yue,Shao-Chao Sun,Shao-Ni Sun,Xue-Fei Cao,Tong-Qi Yuan,Jia-Long Wen
Developing a biorefinery process for a highly integrated valorization and fractionation of lignocellulose is crucial for its utilization. Herein, a biphasic system comprising choline chloride/lactic acid and 2-methyltetrahydrofuran with Al 2 (SO 4 ) 3 and H 2 SO 4 as catalysts was applied to pretreat Eucalyptus . Results showed that under the optimized conditions (150 °C, 30 min, 0.2 M Al 2 (SO 4 ) 3 , 0.075 M H 2 SO 4 ), the furfural yield and enzymatic hydrolysis efficiency could reach 54.7% and 97.0%, respectively. The efficient cellulose conversion was attributed to remarkable removal of lignin (91.0%) and hemicelluloses (100.0%), thereby causing the disruption of cell wall structure and enhancement of cellulose accessibility. Meanwhile, confocal Raman microscope and atomic force microscope displayed that the pretreatment resulted in the decreasing intensities of carbohydrates and lignin different regions of cell walls, and exposing of the embedded microfibers from noncellulosic polymers. Overall, the deep eutectic solvent-based biphasic system displayed high performance for effective utilization of carbohydrate components in lignocellulose.
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PubMed
高影响因子
FUEL
·
2022
·
IF 8.035
Zhi Hu,Aidi Xie,Chun Chen,Zidan Zou,Yue Shen,Zhen Fu,Yunxia Zhang,Haimin Zhang,Huijun Zhao,Guozhong Wang
Aqueous-phase hydrogenation-rearrangement tandem (AP-HRT) reaction is a green and sustainable route to produce cyclopentanone from bio-based furan compounds. Herein, the ionic liquid was applied as the precursor to synthesize Ni@NP-C catalyst, which contains high dispersed nickel nanoparticles (Ni NPs) encapsulated in the N, P co-doped carbon layer , for the selectivity transformation of furfural towards cyclopentanone. The synthesized Ni@NP-C catalyst can afford 100% FAL conversion and 86.7% CPO yield at 130 °C and 1.5 MPa H 2 within 2 h AP-HRT reaction. The introduction of the electronegative heteroatom on the surface can not only improve the adsorption of reactant but also provide weak Lewis Acid sites for being beneficial to the high selectivity of cyclopentanone. The catalyst displays superior activity, selectivity, and stability in the tandem catalytic system in view of the tunable chemical states of the doped heteroatoms by handily adjusting the pyrolysis temperature.
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高影响因子
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
·
2022
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IF 4.326
Xiao Chen,Wenqi Liu,Jingjie Luo,Hongyu Niu,Rongrong Li,Changhai Liang
The hydrogenation of furfural containing multifunctional group often needs the high-efficiency cooperation of multiple catalytic active centers, which is greatly determined by the regulation of the surface and interface structure of multicomponent catalytic materials. Based on such circumstance, a series of highly dispersed supported bimetallic Cu–Ni catalysts prepared by the in situ topological transformation of layered double hydroxides have been investigated for the one-pot hydrogenation of furfural. Compared with the supported monometallic Cu and Ni catalysts, the optimized bimetallic Cu1Ni3/MgAlO catalyst presents highly efficient and good selectivity in the hydrogenation of furfural at the bath reactor. The selectivity to tetrahydrofurfuryl alcohol reaches 94.0% with a complete conversion of furfural at 110 °C under 3 MPa of H2 for 3 h. The results of TEM and in situ FT-IR confirm that the Ni-rich Cu–Ni alloy in the Cu1Ni3/MgAlO catalyst generates a strong synergistic effect, which shifts the adsorption configuration of furfural from parallel or vertical adsorption to tilted adsorption so as to significantly improve the catalytic performance. The intrinsic catalytic performances of CuxNiy/MgAlO catalysts indicate that the TOFC═O and TOFC═C values can be balanced through construction of the structure of the catalyst for achieving the synergistic effect between Cu and Ni significantly to enhance the one-pot selective hydrogenation of furfural to tetrahydrofurfuryl alcohol. Additionally, the Cu1Ni3/MgAlO catalyst presents excellent reusability by six-cycle testing. The above results indicate that the Cu1Ni3/MgAlO with the cooperation of multiple catalytic active centers is a promising catalyst for the selective hydrogenation of furfural.
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高影响因子
Journal of Environmental Chemical Engineering
·
2021
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IF 5.909
Putrakumar Balla,Prem Kumar Seelam,Ravi Balaga,Rajendiren Rajesh,Vijayanand Perupogu,Tong Xiang Liang
Sustainable catalysis is the key for the future progress toward biorefinery and bioeconomy. In this work, we designed and developed an inexpensive and eco-friendly Ni@C catalyst for selective hydrogenation of biomass-based platform molecules. A facile synthesized Ni nanoparticles encapsulated in a stabilized carbon support derived from a sacrificial agent copolymer-gel was investigated in the hydrogenation of furfural (FA) to tetrahydrofurfuryl alcohol (THFOL) and levulinic acid (LA) to γ-valeralactone (GVL). The aim is to study the two different reactions over a highly stabilized Ni nanoparticles embedded in the carbon matrix. The Ni@C was found to be active and selective in multi-catalyzed hydrogenation reactions. The Ni nanoparticles with small and ultra-fine sizes are highly dispersed over the carbon matrix. This was concluded through high-resolution micrography images (SEM, TEM) and XRD patterns. In both reactions, a complete conversion of furfural and levulinic acid was achieved with maximum selectivity over the Ni@C catalyst. The effect of reaction temperature, solvent type, reaction time, and H 2 pressure were also studied. Overall, optimized reaction conditions were determined, and the Ni@C is easily reusable and exceptionally durable in the studied reaction cycles. The apparent activation energies for FA hydrogenation to THFOL and LA hydrogenation to GVL are 15.4 kJ/mol and 33.6 kJ/mol, respectively.
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高影响因子
JOURNAL OF RARE EARTHS
·
2021
·
IF 3.712
Xianghua He,Ben Dai,Yafang Zhang,Dan Zhao,Dihui Zhang,Ruping Liang,Chao Chen
Efficient and applicable catalysts are highly desirable for advanced biomass transformation industry, here, we fabricated a series of Nd-Co-P catalysts for hydrogenation of furfural (FAL) to furfuryl alcohol (FOH). By comprehensive characterizations, it is demonstrated that the prepared Nd-Co-P samples are structured as (NdPO 4 ) m /Co 2 P nanocomposites with molar ratio ( m ) in range of 0.24–1.1; by manipulating m , the outstanding catalytic efficiency comparable with the performance of precious metal catalysts , such as turnover frequency (TOF) up to 0.50 s −1 (being ten-fold higher than Co 2 P) and FOH yield up to 97%, is achieved on the reusable (NdPO 4 ) m /Co 2 P composites. Temperature programmed desorption (TPD), in-situ infrared spectroscopy (IR) and kinetic-mechanism studies further disclose that Co 2 P is decisive for activating FAL, instead, NdPO 4 possesses unique capability of activating hydrogen which readily facilitate the selective hydrogenation of FAL to FOH through a rapid Langmuir–Hinshelwood process over (NdPO 4 ) m /Co 2 P catalyst. These results indicate that rare-earth phosphates like NdPO 4 can act as the promising and reliable catalytic component to activate hydrogen, which can be of interest not only for innovating novel and applicable non-metallic catalysts for sustainable biomass transformation analogous to hydrogenation of FAL, but also for expanding material base for other green mass transformation techniques involving hydrogen.
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高影响因子
CHROMATOGRAPHIA
·
2020
·Vol. 83
·期 8
·927-932
·
IF 1.596
Liu Xiaobo,Zhang Ying,Shang Meijie,Zhu Liping,Yu Min
The effects of furoic acid and furfuryl alcohol on the detection of furfural in transformer oil were studied using the traditional liquid–liquid extraction combined with high-performance liquid chromatography (LLE-HPLC) technology, in which, the methanol used as extraction agent and the C18 column and ultraviolet−visible detector were used as the separation and detection units for the determination of the furfural. The results show that the presence of furfuryl alcohol or furoic acid increases the extraction efficiency of furfural from 42.07 to 73.21% and 65.33%, respectively. The extraction efficiency of furfural decreases when the concentrations of furfuryl alcohol increase from 0.2 to 0.6 mg L −1 , but the extraction efficiency of furfural increases with the concentrations of furoic acid from 0.2 to 0.6 mg L −1 . This indicated that the accuracy of detection and extraction efficiency of furfural in transformer oil by LLE-HPLC technology may be affected by the furfuryl alcohol or furoic acid dissolved in transformer oil.
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