Future Foods
·
2025
·
IF 8.2
Jiaojiao Liang,Xinyu Shen,Ziyou Liu,Yixin Hu,Hui Xu,Zimeng Yang,Fei Xie,Jinping Cao,Yue Wang,Chongde Sun
In this study, air nanobubbles (NBs) generated with a new device were stabilised by a complex of arabic gum (AG) and stevioside (STE). Some basic metrics of NBs produced by biosurfactants at different concentrations were characterized to determine the stability of NBs. The mixture solution rich in NBs was assisted by ultrasonic disruption (UD) to extract total phenols (TP) and total flavonoids (TF) from 7 citrus pericarp. We evaluated four key factors affecting the TF extraction of ‘ Citrus reticulata 'Chachiensis '’ (‘Chazhigan’) pericarp by one-way test. The optimal extraction conditions were further predicted and validated by Box-Behnken response surface experiments. Under the conditions of 135 w capacity, 4.1 C mixture solution concentration, 30.5°C water bath temperature, and 31min ultrasonic time, the TF content of ‘Chazhigan’ pericarp (20.82±0.85 mg/g DW) was significantly better than that extracted by 80% ethanol (12.22±0.90 mg/g DW). Finally, fourier transform infrared (FT-IR) spectroscopy, scanning electron microscopy (SEM) and transmission electron microscopy (TEM) were utilised to provide a preliminary exploration of the potential mechanisms involved in the extraction process. The flavonoid extracts from the pericarp of ‘Chazhigan’ were qualitatively analysed. And the differences in the chemical antioxidant activity of their extracts were investigated before and after the application of traditional alcoholic extraction and novel green extraction. In conclusion, this study established a novel approach that is eco-friendly, which could effectively extract flavonoids from citrus peels.
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ACS Nano
·
2025
·
IF 16
Xiaofeng Lu,Dong Zhong,Qi An,Liting Kang,Na Fan,Junjie Cao,Renjie Li,Qianqian Cao,Yudong Zhou,Xiaoyu Du,Shuanghong Yan,Juan Li,Xiaolei Qu,Yuqin Wang
Perfluoroalkyl and polyfluoroalkyl substances (PFASs) make up a large class of emerging chemical pollutants that have caused extensive contamination of global water sources. As the toxicity of PFAS becomes increasingly recognized, there is a growing demand for low-cost and rapid sensors capable of screening water samples for multiple PFAS species. However, most electrochemical and optical sensors can detect only one or two PFASs, despite the high structural diversity of these compounds in aquatic environments. Here, we report a single-molecule nanopore sensor that enables simultaneous detection of nine PFASs in a single measurement. By incorporating a β-cyclodextrin (β-CD) adapter into a mutant α-hemolysin (α-HL) nanopore, translocating PFAS molecules produce distinct current blockades that allow clear discrimination based on carbon chain lengths, hydrogen substitutions, and terminal functional groups. With assistance from a machine learning classifier, an overall identification accuracy of 95.83% is achieved. This strategy allows direct, label-free, and rapid discrimination of multiple PFASs in surface water samples at environmentally relevant concentrations as low as the microgram per liter level, without chemical labeling, separation, or enrichment. The successful demonstration of nanopore sensing in complex real-world matrices highlights its strong potential for practical, field-deployable environmental analysis.
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PubMed
高影响因子
Fermentation-Basel
·
2025
·Vol. 11
·期 11
·609
·
IF 3.3
Run Huang,Ying-Ying Xie,Xin-Yu Liu,Huai-Hui Yi,Hao-Jie Xu,Liang Zhang,Hui-Mei Cai,Zheng-Quan Liu,Da-Xiang Li,Yun-Qiu Yang,Xiao-Chun Wan,Chuan-Yi Peng
Brick tea is a type of post-fermented food that involves microorganisms. Long-term consumption of brick tea exposes consumers to high fluoride levels, which can adversely affect their health. This study explored the feasibility of selective defluorination of Qingzhuan brick tea through membrane separation technology, and pilot production was conducted to produce defluorinated instant brick tea. The concentration of tea polyphenols increased by more than 10 times after nanofiltration, demonstrating the high selectivity of nanofiltration membranes toward fluoride. Defluorination trends were studied at different initial material concentrations (0.5–4%) and operating pressures (0.1–0.5 MPa) under cyclic defluorination. Defluorinated instant brick tea products were also industrially prepared using 300- (DF-300) and 1000-Da (DF-1000) membranes, followed by vacuum freeze-drying. The DF-1000 and DF-300 products exhibited a defluorination rate of 51.46% and 67.96%, respectively. The products have excellent characteristics in terms of color, aroma, and flavor quality, as well as solubility. Gas chromatography–mass spectrometry indicated that the volatile components in the defluorinated instant brick tea were slightly different from those in the original tea, but the key aroma and flavor characteristics of the defluorinated brick tea remained unchanged. Membrane separation provides technical support for the large-scale production of low-fluoride post-fermented tea.
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JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
·
2025
·Vol. 36
·期 30
·1-21
·
IF 2.8
Yang Minjie,Zou Congyang,Ji Yufeng,Liu Ruijie,Xu Ying
A novel MIL-101(Fe)/Bi₂S₃ Z-scheme heterojunction with a metal–organic framework (MOF) structure was synthesized via a solvothermal method. Compared with pristine MIL-101(Fe) and pristine Bi₂S₃, this composite exhibits a significant breakthrough in degradation performance toward rhodamine B (RhB) and tetracycline hydrochloride (TCH). Specifically, it achieves a degradation efficiency of 95.7% for 20 mg/L TCH within 120 min and 98.6% for 40 mg/L RhB within 90 min.Characterizations including X-ray diffraction (XRD), scanning electron microscopy (SEM), ultraviolet–visible diffuse reflectance spectroscopy (UV–Vis DRS), and electrochemical impedance spectroscopy (EIS) confirm that the MOF structure of MIL-101(Fe) provides a stable support matrix for Bi₂S₃. Moreover, the construction of the Z-scheme heterojunction can effectively suppress the recombination of photogenerated electron–hole pairs while retaining the strongly oxidizing hydroxyl radicals (・OH) and strongly reducing superoxide radicals (・O₂⁻). More importantly, after five recycling cycles, the degradation efficiencies of the composite for TCH and RhB remain at 86.8% and 88.6%, respectively, with no obvious damage to its crystal structure after cycling. This demonstrates superior structural stability and reusability compared to most reported MOF-based photo-Fenton catalysts.
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2025
·
IF 9.7
Yi Jiang,Ruixiang Xu,Wanqiang Liu,Ruifeng Zheng,Zhenyu Hu
In this study, we discovered that Cu 31 S 16 , when used as the cathode in a battery, exhibits a significant “ineffective ion replacement” phenomenon during the first discharge cycle at low voltage. Specifically, Zn 2+ ions engage in an ion exchange reaction with the surface of the Cu 31 S 16 cathode material, irreversibly replacing Cu 2+ ions. Furthermore, we found that the Cu 2+ ions displaced in this process react with H + at the high voltage discharge plateau to form zinc hydroxysulfate (Zn 4 (OH) 6 SO 4 ·XH 2 O), which subsequently transforms into ZnxCu 4-x (OH) 6 SO 4 ·XH 2 O. The microstructure transitions from the characteristic hexagonal plate-like morphology of Zn 4 (OH) 6 SO 4 ·XH 2 O to the hexagonal prismatic cluster structure of ZnxCu 4-x (OH) 6 SO 4 ·XH 2 O. To address this issue, we propose and implement an “Overvoltage Pre-cycle” method, where trace amounts of Zn 2+ are introduced to replace Cu 2+ at the Cu 31 S 16 cathode. This approach stabilizes the surface structure of the cathode, significantly extending its operational lifespan, providing a more stable discharge plateau, and increasing the discharge duration. Comparative analysis reveals that the effective discharge plateau of AHPBs activated through the first cycle “Overvoltage Precycle” reaches 85.5 %, a 14.1 % improvement over the 71.4 % observed for conventionally activated AHPBs. Additionally, the charge-discharge energy conversion efficiency improves from 82.46 % to 83.35 %. Theoretical calculations indicate that the first cycle “Overvoltage Precycle” enhances the surface structure of Cu 31 S 16 as the cathode, and the Zn 2+ doping improves its electrochemical performance by facilitating efficient H + transport. This further deepens our understanding of the H + /Zn 2+ co-intercalation electrochemical behavior, offering new insights for optimizing cathode surface engineering.
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高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2025
·
IF 13.2
Zhiqiang Zhao,Yiwen Huang,Minghao Chao,Silin Du,Junjie Li,Jin Wang,Guangyu Ma,Yufan Liu,Xin Kang,Mengying Fu,Dehong Yu,Shibao Li,Fenglei Gao
Oxygen defect engineering, which precisely modulates the coordination environments and dynamic equilibria of oxygen vacancies (O v ), lattice oxygen (O lat ), and adsorbed oxygen (O ads ), serves as a pivotal strategy for optimizing electronic structures and catalytic pathways in metal oxides and is expected to become a core means to enhance the activity of nanoenzymes. Leveraging optimized component ratios from oxygen defect engineering, we engineered hollow porous nanocages with a distinctive 3D open framework to maximize active site exposure. Controlled reduction reconstructed oxygen species distribution, endowing the material with exceptional peroxidase (POD), oxidase (OXD), and laccase (LAC) activities. Capitalizing on phenolic pollutants' structural features and reducibility, we developed a tri-channel nanozyme sensor array using CuO@Pd nanocages. This system enables efficient oxidative degradation and precise identification of six phenolic compounds through synergistic triple-enzyme catalysis. Transcending the pH limitations of conventional sensors, the array differentiates phenolic analogues across concentrations with broad linear ranges and high sensitivity. This work establishes a direct methodology for modulating nanozyme activity via oxygen defect engineering while elucidating the electron-transfer mechanism in Pd Cu redox cycling.
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CHEMICAL PHYSICS
·
2025
·
IF 2.4
Qiuhui Zhao,Yaqi Jing,Jiale Zhang,Jiadan Xue,Jianjun Liu,Jianyuan Qin,Zhi Hong,Yong Du
Isoniazid (INH), a frontline anti-tuberculosis drug, faces rising resistance and hepatotoxicity, motivating crystal-engineering approaches. The INH-4-hydroxybenzoic acid (INH-HBA) cocrystal shows multiple polymorphs, its hydrate exists in two forms whose lattice water markedly alters hydrogen-bond topology and molecular packing. We combined terahertz time-domain spectroscopy (THz-TDS) and FT-Raman spectroscopy with periodic solid-state DFT and potential energy distribution (PED) analysis to assign vibrational modes and link spectral features to structural motifs. Hirshfeld surface analysis indicates form I is dominated by multi-directional O H...N contacts and an R 2 2 ( 8 ) N H...O synthon that yields parallel layered packing. By contrast, form II uses lattice water to bridge O H...O/N H...O interactions and weak C H...O contacts, producing a cross-stacked three-dimensional network lacking R 2 2 ( 8 ) dimers. Observed spectral differences are attributed to these distinct intermolecular interactions and associated vibrations. By integrating experimental and theoretical data, this study provides spectroscopic-structural insights into INH-HBA hydrate polymorphism, offering a foundation for pharmaceutical cocrystal identification and design.
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Journal of Environmental Chemical Engineering
·
2025
·
IF 7.2
Xiaoxian Cai,Ke Chen,Lixue Zheng,Huijun Guan,Tianlong Hao,Wenqing Zhou,Jingjing Yang,Lihua Qi,Chunfeng Guan
The widespread accumulation of organic pollutants in agricultural soils, such as dimethyl phthalate (DMP), poses serious risks to human health and ecological safety. The application of plant growth-promoting rhizobacteria (PGPR) to improve phytoremediation efficiency for organic pollutant-contaminated soils has gained increasing attention. However, synergistic PGPR-plant signaling and competitive root colonization of PGPR directly affect the remedial efficiency of the PGPR-plant system for soil organic pollutants. Acyl-homoserine lactones (AHLs), one of the quorum sensing (QS) signals, can enhance microbial cooperation and promote plant growth, thereby probably facilitating phytoremediation processes for pollutant degradation. In this study, the potential capacity of AHLs to assist PGPR in the phytoremediation of DMP-polluted soils was explored, with a focus on their effects on DMP removal, plant physiological functions, and rhizosphere microbial community structure. The results showed that AHLs (C 4 -HSL)-assisted PGPR ( Bacillus YT2) treatment significantly increased DMP removal to 92.60 % and improved plant growth. Compared to the individual AHLs or PGPR treatments, the AHLs-assisted PGPR more effectively enhanced plant photosynthesis, osmoregulation, and antioxidant capacity, reduced oxidative damage, and improved soil enzyme activity and nutrient availability. Additionally, the AHLs-assisted PGPR treatment modulated microbial community in the rhizosphere, increasing the richness of pivotal functional taxa such as Xanthomonadaceae and Acidobacteriota. AHLs might directly promote DMP degradation by regulating the QS system and enhancing plant-bacterial communication, while also indirectly supporting plant growth through stress tolerance enhancement. In conclusion, AHLs-mediated enhancement of PGPR functionality provides a promising approach for remediating DMP-contaminated soils and offers a theoretical basis for developing composite microbial formulations.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2025
·
IF 8.5
Lele Chen,Shaofei Zhang,Tingyu Liang,Xu Ding,Ling Ding,Jipeng Shi,Ji Zhang,Jianping Wu
The therapeutic potential of essential oils in feed and medicine is limited by their volatility, degradation, and poor bioavailability. To overcome these challenges, a novel colon-targeted microsphere was engineered for the controlled delivery of tea tree essential oil (TEO), as illustrated in Scheme 1 . A critical component of this system is a pH-responsive coating composed of pectin and starch, which acts as a colon-specific polymeric barrier. This coating demonstrated precise pH-responsive release, with minimal leakage in simulated gastric fluid (SGF) (only 10.87 % release over 4 h) and sustained, colon-specific release in simulated intestinal fluid (SIF) (79.77 % over 14 h). The core of the system, designated TEOCMT, was fabricated through the modification of montmorillonite (MMT) with cetyltrimethylammonium bromide (CTAB), resulting in organo-montmorillonite (CMT). Tea tree essential oil was then encapsulated within the interlayer spaces of CMT, forming an effective sustained-release system (TEOCMT). Compared to raw MMT (5.63 %), the TEO loading capacity of CMT increased 8.3-fold, reaching 46.79 %. Furthermore, the antibacterial activity of PS/TEOCMT microspheres was triggered in alkaline media, where they dissolved and released the TEOCMT core. This resulted in enhanced efficacy, particularly against S. aureus (MIC = 1.25 mg mL −1 ), which was superior to that of pure TEO (MIC = 2.5 mg mL −1 ). The PS/TEOCMT microspheres also exhibited excellent biocompatibility. This work presents a robust and effective strategy for unlocking the full potential of essential oils in colon-specific applications.
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高影响因子
Applied Materials Today
·
2025
·
IF 6.9
Jun Zeng,Tao Jia,Tong Chen,Huilin Liu,Zhaojie Sun,Xiaoyong Huang,Yunfei Shang,Shuwei Hao,Chunhui Yang
Cancer phototheranostics has emerged as a cornerstone of personalized precision medicine to achieve efficient and targeted tumor treatment. Upconversion nanoparticles (UCNPs)-mediated phototheranostics exhibited remarkable potential for imaging diagnostics and therapeutic applications. Nevertheless, integrating programmable photoactivation functions of imaging and therapy within a single UCNP with negligible phototoxicity remains a huge challenge, primarily due to the absence of precise photoswitching strategies. Herein, a pulse-responsive upconversion nanoagent (UCNA) is designed to enable imaging-guided precision phototherapy through tunable red/green emissions. The UCNA is constructed based on a UCNPs@mSiO 2 core–shell structure conjugated with photosensitizer (neutral red) and drug (curcumin), and gated by a β-cyclodextrin-adamantane (β-CD-AD) host–guest supramolecular complex. The red emission is utilized for determining the tumor area through fluorescence imaging under 980 nm laser irradiation with a long pulse width (LPW). By switching the laser duty cycle into a short pulse width (SPW) mode, the resultant green emission can active photosensitizer to produce cytotoxic singlet oxygen ( 1 O 2 ), and simultaneously trigger drug release for antitumor therapy. The results demonstrate the attractive performance of UCNP-mediated deep-tissue imaging and enhanced anti-tumor efficacy without obvious systemic toxicity. In general, this work provides a facile approach for tuning upconversion emission, thereby realizing the photoswitchable activation of imaging diagnostics and photodynamic therapeutics.
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Journal of Environmental Chemical Engineering
·
2025
·
IF 7.2
Peng Gao,Min Zheng,Mengni Zhou,Yiwei Ma,Guirong Bao,Chengyan Wang
The valorization and toxicity reduction of phenolic substances are critical challenges for achieving green and sustainable development in the petroleum, coal, and biomass industries. This study investigated the phenolic model compound guaiacol hydrodeoxygenation over Ru/Al 2 O 3 catalysts, demonstrating that synthesis within an anaerobic glovebox significantly enhances catalytic activity compared to ambient synthesis. Four solvents (ethanol, methanol, tetrahydrofuran, and n-dodecane) were evaluated for their impact on guaiacol conversion and product distribution. Experimental results demonstrated that non-polar n-dodecane achieved 100 % guaiacol conversion and 92.8 % cyclohexane selectivity, attributed to weak catalyst-solvent interactions verified by first-principles calculations. Reaction optimization enabled > 90 % yields of 2-methoxycyclohexanol, cyclohexanol, and cyclohexane. Crucially, a novel low-temperature demethoxylation pathway via the intermediate 2-methoxy-1-cyclohexen-1-ol was identified through quantum chemistry calculations, offering a strategy to enhance cyclohexanol production. Kinetic analysis revealed apparent activation energies of 55 kJ/mol (demethoxylation) and 72 kJ/mol (dehydroxylation). The catalyst maintained stable performance over five cycles. These findings underscore the critical importance of catalyst synthesis, solvent environment, and reaction control in achieving efficient and selective guaiacol hydrodeoxygenation, offering strategies for green valorization and toxicity reduction of phenols.
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Journal of Environmental Sciences
·
2025
·
IF 6.3
Shiyu Yuan,Jingyao Ping,Huayi Chen,Jie Liu,Zewen Tan
The extensive use of chloramphenicol (CAP) in livestock leads the accumulation of CAP in livestock manures, threatening environmental and human health. Therefore, eliminating or reducing CAP concentration in manures before its re-utilization and application through microbial remediation is necessary. In this study, Exiguobacterium sp. CAP4, isolated from the plastisphere in duck manures, was capable of degrading CAP with the biodegradation efficiency of 97.8 % at initial CAP concentration of 5 mg/L within 4 days. A total of twenty-four biotransformation products were determined, including two novel transformation products, TP166 and TP203, enriched the integrity of CAP biodegradation pathways. Furthermore, the biotransformation process was proposed as a detoxifying process through biotransformation products toxicity evaluation. Notably, Exiguobacterium sp. CAP4 successfully colonized in the cow manures after inoculation, and bioaugmented the biodegradation of CAP in virgin cow manures. This study significantly extended our understanding of the CAP biotransformation fate, and provided a promising bacterial strain for bioremediation of CAP containing wastewater in situ .
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危险品化学品经营许可证（带存储）