INORGANIC CHEMISTRY
·
2021
·
IF 5.165
Xuping Shi,Wenbin Zhang,Wenbing Cai,Shujuan Han,Zhihua Yang,Shilie Pan
In virtue of the essential role in controlling polarized light, outstanding ultraviolet (UV) and deep-ultraviolet (DUV) birefringent crystals are imperative in many advanced optical instruments. To design the UV and DUV crystals with large birefringence, we paid more attention to combining the excellent gene, π-conjugated [BO3] unit and metal cations beneficial to blue-shift the cutoff edge; finally, two rare-earth borates Li3La2(BO3)3 and Li1.75Na1.25La2(BO3)3 have been synthesized using the high-temperature solution method. Compared with Na3La2(BO3)3, Li3La2(BO3)3 and Li1.75Na1.25La2(BO3)3 are isostructural, and the isolated [BO3] units are arranged nearly parallel to each other in the structure, which is conducive to generating a larger birefringence. The structural comparison between the two crystals and Na3La2(BO3)3 indicates that the various coordination environments of alkali metal cations play an important role in the evolution of the crystal structure from Li3La2(BO3)3 and Li1.75Na1.25La2(BO3)3 to Na3La2(BO3)3. This work can contribute to a better understanding of the enhancement in birefringence from Na3La2(BO3)3 (0.023 @ 1064 nm) to Li3La2(BO3)3 (0.078 @ 1064 nm) with the perspective of structure–property relationships. Meanwhile, the two title crystals possess the DUV cutoff edge (<190 nm), suggesting that they can be applied as the DUV birefringent crystals.
研究领域:
材料科学
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光学材料
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无机化学
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晶体工程
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DOI
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CERAMICS INTERNATIONAL
·
2022
·
IF 5.532
Hongrui Jia,Jiahao Mi,Zhen Li,Linghang Wang
Sm-doped Pb(Mg 1/3 Nb 2/3 )-PbTiO 3 (PMN-PT) binary ferroelectric ceramics has received extensive attention due to the excellent dielectric and piezoelectric properties . However, its Curie temperature ( T c ) is greatly reduced by Sm doping and T c is only 89 °C at the optimum piezoelectric coefficient. In this work, Sm-doped Pb(Mg 1/3 Nb 2/3 )O 3 –Pb(Zn 1/3 Nb 2/3 )-PbTiO 3 (Sm: PMN-PZN-PT) ternary ferroelectric ceramics near MPB were successfully manufactured and the crystal structure, microstructure and electric properties were investigated with respect to Sm doping content. A high piezoelectric coefficient of 870 pC/N and a high T c of 146 °C were achieved simultaneously in PMN-PZN-PT ternary ceramics with 1% Sm doping content. In addition, the room temperature dielectric constant was greatly improved by Sm doping and the P r , P s and E c values gradually decrease with the increase of Sm content. These results indicate that Sm-doped PMN-PZN-PT ceramics may be an attractive material for high performance piezoelectric device applications.
研究领域:
材料科学
·
物理学
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DOI
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TURKISH JOURNAL OF CHEMISTRY
·
2024
·Vol. 48
·期 4
·597-619
·
IF 1.3
YUAN HANG,CAO GUI-PING,LV HUI
The reaction solvent and catalyst play an essential role in the Prins reaction for the synthesis of 3-methyl-3-buten-1-ol (MBO) from formaldehyde and isobutene. The reactivity of the solid base catalyzed Prins condensation reaction by formaldehyde and isobutene in supercritical CO2 was investigated using CsH2PO4 modified HZSM-5. We finds that the alkaline sites of the alkali-loaded catalyst can extract the α-H on isobutene to generate olefin carbon negative ions, while the supercritical CO2 with weak Lewis acidity can activate formaldehyde to carbon positive ions, which can combine more easily with the carbon negative isobutene to react, thus improving the reactivity of the reaction system.
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CHINESE CHEMICAL LETTERS
·
2025
·
IF 8.9
Haoran Yu,Liang Cao,Jiajia Wang,Jian Guo,Ji Zhang,Shan-Tao Zhang
Piezoelectric materials have wide commercial applications involving our everyday lives. The common categorized “soft” and “hard” piezoelectric materials have distinct even contradictory performance parameters typically exemplified by piezoelectric coefficient d 33 and mechanical quality factor Q m . However, for some special devices operated in resonant mode, simultaneously high or at least balanced performance parameters are needed. Here, we show the transition from “soft” to “hard” performance in 2 mol% Sm doped (0.36- x )Pb(Ni 1/3 Nb 2/3 )O 3 - x Pb(Mn 1/3 Nb 2/3 )O 3 -0.28PbZrO 3 -0.36PbTiO 3 quaternary solid solution piezoceramics, for which the d 33 and planar electromechanical coupling factor k p decrease, while Q m and Curie temperature T c increase monotonously with increasing x value. As the results, balanced performance with moderate d 33 = 446 pC/N, k p = 0.49, Q m = 425, and T c = 170 °C are achieved around x = 0.03. This work not only shows the feasibility for combining “soft” and “hard” performance by forming appropriate solid solutions, but also provides a suitable material basis for further simultaneously optimizing piezoelectric parameters.
研究领域:
材料科学
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功能陶瓷
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压电材料
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固溶体
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介电物理
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产品关联
DOI
高影响因子
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
·
2014
·
IF 3.432
Jing Wu,Linxi Yu,Feifei Yang,Jingjie Li,Peng Wang,Wenbo Zhou,Liwen Qin,Yunqi Li,Jian Luo,Zhengfang Yi,Mingyao Liu,Yihua Chen
A series of 2,3-diaryl-4-thiazolidinone derivatives were synthesized and evaluated for their antiproliferative properties against two well-known cancer cell lines (A549 as human lung cancer and MDA-MB-231 as human breast cancer). Structure activity relationship (SAR) analysis resulted in the discovery of 2-(3-(arylalkyl amino carbonyl)phenyl)-3-(2-methoxy-phenyl)-4-thiazolidinone derivatives with high potent inhibitory effects on the proliferation of both cancer cell lines. Furthermore, several compounds with potent antiproliferative activities displayed excellent inhibitory activities on migration with an IC 50 of about 0.05 μM on MDA-MB-231 cells in two different migration assays. In particular, compound 39 was indicated to suppress tumor growth and metastasis as well as promote survival rate. Intriguingly, this series of analogs have been indicated to inhibit tumor cell proliferation through inducing cell cycle arrest . These results suggested that the new series of 2-(3-(arylalkyl amino carbonyl)phenyl)-3-(2-methoxyphenyl)-4-thiazolidinone derivatives could be regarded and developed as novel highly potential anticancer agents in the future.
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DOI
PubMed
高影响因子
MICROCHEMICAL JOURNAL
·
2023
·
IF 4.8
Li Huang,Shangying Qin,Yuanjin Xu,Shiqi Cheng,Jin Yang,Yilin Wang
MnO 2 nanosheets (MnO 2 NSs) were prepared and used as both oxidant of 3, 3′, 5, 5′- tetramethylbenzidine (TMB) and recognizer of UA, a simple colorimetric approach for sensitive detection of uric acid (UA) was established. In the medium of weak acid, MnO 2 NSs exhibited strong oxidation capacity and could oxidize colorless TMB to generate a blue oxidation product (oxTMB) with an absorbance signal. However, the introduction of UA could inhibit MnO 2 NSs - mediated TMB oxidation and reduce the formation of oxTMB, resulting in the blue fading and the absorbance weakening. Under the conditions of incubation time 20 min, pH 3.0, TMB 0.5 mM, and MnO 2 NSs 50 μM, the decrease in absorbance was linearly dependent on UA concentration in the range of 0.5–30.0 μM with a detection limit of 0.21 μM. Furthermore, the approach has been applied for determining UA in human urine samples with recoveries between 93.1 and 102.4 % and relative standard deviation less than 3.0 %.
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产品关联
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Frontiers in Pharmacology
·
2023
·
IF 5.6
Chen Lexian,Lv Qianqian,Cai Jianghong,Liang Jiajie,Liang Ziyan,Lin Jiahui,Xiao Ying,Chen Ruiyao,Zhang Zhiling,Hong Yue,Ji Hong
Coumarin derivatives have diverse structures and show various significant biological activities. Aiming to develop more potent coumarin derivatives for cancer treatment, a series of coumarin acrolein hybrids were designed and synthesized by using molecular hybridization approach, and investigated for their antiproliferative activity against A549, KB, Hela and MCF-7 cancer cells as well as HUVEC and LO2 human normal cells. The results indicated that most of the synthesized compounds displayed remarkable inhibitory activity towards cancer cells but low cytotoxicity on normal cells. Among all the compounds, 5d and 6e were the most promising compounds against different cancer cell lines, especially for A549 and KB cells. The preliminary action mechanism studies suggested that compound 6e, the representative compound, was capable of dose-dependently suppressing migration, invasion and inducing significant apoptosis. Furthermore, the combined results of network pharmacology and validation experiments revealed that compound 6e induced mitochondria dependent apoptosis via the PI3K/AKT-mediated Bcl-2 signaling pathway. In summary, our study indicated compound 6e could inhibit cell proliferation, migration, invasion and promote cell apoptosis through inhibition of PI3K/AKT signaling pathway in human oral epidermoid carcinoma cells. These findings demonstrated the potential of 3-(coumarin-3-yl)-acrolein derivatives as novel anticancer chemotherapeutic candidates, providing ideas for further development of drugs for clinical use.
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DOI
PubMed
高影响因子
JOURNAL OF SOL-GEL SCIENCE AND TECHNOLOGY
·
2018
·Vol. 85
·期 3
·506-513
·
IF 1.745
Fei Zhifang,Yang Zichun,Chen Guobing,Li Kunfeng
Abstract Polyimide cross-linked silica aerogels with different weight percentages of polyimide were prepared through sol–gel technology and supercritical CO 2 fluid drying technology. Tetraethoxysilane (TEOS) was used as a silica source precursor, 3-aminopropyltriethoxysilane (APTES) end-capped polyimide was used as a cross-linking agent, derived from 3, 3′, 4, 4′-biphenyltetracarboxylic dianhydride (BPDA) and 4, 4′-oxydianiline (ODA). The acid produced during the imidization process catalyzed the hydrolysis reaction without additional catalyst. After condensation reaction catalyzed by ammonium hydroxide solution, the polyimide cross-linked silica gels were obtained and then dried in supercritical CO 2 . The polyimide cross-linked silica aerogels have low density (0.132~0.187 g/cm 3 ), high specific surface area (623–741 m 2 /g), low thermal conductivity (0.0306~0.0347 W/m K at room temperature), relatively high compressive strength (1.03~3.82 MPa) and high thermal decomposition temperature (360 °C). This research provided a simple and efficient method that used the polyimide as a strengthening phase to improve the mechanical properties of TEOS-based silica aerogels.
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产品关联
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MATERIALS SCIENCE FORUM
·
2017
·
IF 0
Heng Xue Xiang,Zi Ye Chen,Wei Chen,Zhe Zhou,Bin Sun,Mei Fang Zhu
As a potential material for food packaging, fully biodegradable composite films based on novel functionalized natural polyphenol/Poly (3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) were successfully fabricated by solution casting, and also the functionalized natural polyphenol (C18TAx) was synthesized by grafting fatty acid onto natural polyphenol Tannic Acid (TA). The resultant C18TAx with better hydrophobicity was uniformly dispersed into a PHBV matrix. The influence of C18TAx dosage on the mechanical behavior, crystallization behavior and thermal properties of the C18TAx/PHBV composite films was investigated by uniaxial tensile mechanical testing, Differential Scanning Calorimeter (DSC), Polarizing Optical Microscope (POM) and Wide Angle X-ray Diffractometry (WAXD). The results revealed that the x value was about 0.09, showing that about 11/20 phenol hydroxy groups in TA molecules were replaced with fatty acid chains. Compared with those of neat PHBV, the tensile strength and elongation at break of the C18TA0.09/PHBV composite films with 10 wt.% C18TA0.09 content were enhanced by 121%, and 458%, respectively. This improvement was primarily ascribed to intermolecular hydrogen bonding interactions in composite films. This new type of fully biodegradable bio-based composite films shows great potential for food packaging.
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产品关联
DOI
INORGANIC CHEMISTRY
·
2022
·
IF 5.436
Jingjing Zhai,Fen You,Suting Xu,Ao Zhu,Xiaohui Kang,Yat-Ming So,Xiaochao Shi
A PNP-pincer ligand provides a versatile ligation framework, which is highly useful in organometallic chemistry and catalytic chemistry. In this work, by a de novo strategy, a simple and efficient synthetic pathway, has been developed to prepare the new iminodibenzyl-based PNP pincer proligand imin-RPNP(Li or H) (R = isopropyl, phenyl). By employing salt metathesis or direct alkyl elimination, we successfully synthesized a series of iminodibenzyl-PNP rare-earth-metal (Ln = Sc, Y, Dy, Ho, Er, Tm, Lu) complexes and characterized them by NMR and X-ray diffraction analyses. Upon addition of a borate and triisobutylaluminum (TIBA), the rare-earth-metal complexes 2-Y, 2-Dy, 2-Ho, 2-Er, and 2-Tm bearing the imin-PhPNP ligand exhibited unexpectedly high 3,4-selectivity (up to 95%) for the polymerization of 1,3-dienes (isoprene and myrcene); in particular, the chosen yttrium complex 2-Y promoted the 1,3-diene polymerization in a living manner. A computational study suggested that the sterically congested configuration around the metal center imposed by the imin-RPNP ligand might be the main reason for this unusual selectivity.
研究领域:
有机金属化学
·
催化化学
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DOI
高影响因子
European Physical Journal-Special Topics
·
2022
·Vol. 231
·期 6
·1215-1219
·
IF 2.891
Li Ruidong,Deng Jinxiang,Chen Liang,Kong Le,Wang Xiaolei,Meng Junhua,Sun Junjie,Zhang Xiaoxia,Zhang Jie,Wang Guisheng,Yang Qianqian,Gao Hongli
In this paper, rubrene:MoO \(_{3}\) mixed films were deposited on quartz glass and p-Si substrates using thermal evaporation technique. We fabricated the devices based on rubrene:MoO \(_{3}\) mixed films in the form of Al/rubrene:MoO \(_{3}\) /p-Si/Al. The electrical characteristics of the rubrene:MoO \(_{3}\) film (with 1:1 weight ratio)-based devices were measured using Hall system. The results indicate the enhanced hole concentration and hole carrier mobility. In addition, the presence of charge transfer complexes leads to an increase of the conductivity and the contact between sample and electrode is almost Ohmic contact. To investigate the effect of MoO \(_{3}\) , the rubrene:MoO \(_{3}\) mixed films with different concentrations of MoO \(_{3}\) were deposited using thermal evaporation technique and the Schottky barrier devices based on rubrene:MoO \(_{3\, }\) mixed films were fabricated. The electrical characteristics demonstrate that the charge transfer complex had been formed when rubrene and MoO \(_{3}\) mixed. Our results demonstrated improvement of the contact between electrode and sample in electronic devices.
研究领域:
材料科学
·
电子工程
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DOI
高影响因子
Frontiers in Bioengineering and Biotechnology
·
2022
·
IF 6.064
Liu Wei,Yuan Shan,Jin Miaomiao,Xian Mo
Fluorine has become an important element for the design of synthetic molecules for use in medicine, agriculture, and materials. The introduction of fluorine atoms into organic compound molecules can often give these compounds new functions and make them have better performance. Despite the many advantages provided by fluorine for tuning key molecular properties, it is rarely found in natural metabolism. We seek to expand the molecular space available for discovery through the development of new biosynthetic strategies that cross synthetic with natural compounds. Towards this goal, 2-fluoro-3-hydroxypropionic acid (2-F-3-HP) was first synthesized using E. coli coexpressing methylmalonyl CoA synthase (MatBrp), methylmalonyl CoA reductase (MCR) and malonate transmembrane protein (MadLM). The concentration of 2-F-3-HP reached 50.0 mg/L by whole-cell transformation after 24 h. 2-F-3-HP can be used as the substrate to synthesize other fluorides, such as poly (2-fluoro-3-hydroxypropionic acid) (FP3HP). Being entirely biocatalytic, our procedure provides considerable advantages in terms of environmental and safety impacts over reported chemical methods.
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高影响因子
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