Marine Drugs
·
2024
·Vol. 22
·期 11
·499
·
IF 4.9
Biyang Zhu,Jiacheng Wang,Lijun You,Lianzhu Lin,Kuncheng Lin,Kseniya Hileuskaya
Calcium-chelated polysaccharides have been increasingly considered as promising calcium supplements. In this study, degraded fucoidans (DFs) with different molecular weights (Mws) were prepared after UV/H2O2treatment; their calcium-chelating capacities and intestinal absorption properties were also investigated. The results showed that the calcium-chelating capacities of DFs were improved with a decrease in Mw. This was mainly ascribed to the increased carboxyl content, which was caused by free-radical-mediated degradation. Meanwhile, the conformation of DF changed from a rod-like chain to a shorter and softer chain. The thermodynamic analysis demonstrated that DF binding to calcium was spontaneously driven by electrostatic interactions. Additionally, DF-Ca chelates with lower Mw showed favorable transport properties across a Caco-2 cell monolayer and could effectively accelerate the calcium influx through intestinal enterocytes. Furthermore, these chelates also exhibited a protective effect on the epithelial barrier by alleviating damage to tight junction proteins. These findings provide an effective free-radical-related approach for the development of polysaccharide-based calcium supplements with improved intestinal calcium transport ability.
研究领域:
食品科学
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营养学
·
生物化学
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高影响因子
CHEMOSPHERE
·
2018
·
IF 4.427
Yihan Zhang,Jing Shi,Zhengwen Xu,Yue Chen,Duanmei Song
Schorl could perform as an extremely promising catalyst for decomposing tetracycline hydrochloride (TC) due to its high degradation efficiency, low cost, chemical stability, easy recovery and repeatable utilization. Comparisons of TC degradation indifferent systems showed that schorl/H 2 O 2 system exhibited the optimum pollutant elimination and TOC removal efficiencies. Kinetics and possible mechanisms of TC degradation were clarified. The OH generated on the schorl surface and O 2 − /HO 2 were the main reactive species responsible for TC oxidation. Six possible intermediates were identified, and possible transform mechanisms and pathways were explored. Active radicals were inclined to attack the C C double bond, dimethylamino and phenolic moieties of TC molecular. The principal intermediate products were generated through N-demethylation, oxidation and rearrangement.
研究领域:
环境科学
·
催化化学
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高影响因子
Journal of Environmental Chemical Engineering
·
2022
·
IF 7.968
Run Yuan,Yu Xia,Xu Wu,Can He,Yihe Qin,Changjun He,Xuewei Zhang,Na Li,Xuwen He
Catalytic oxidation is widely used in the treatment of refractory wastewater. However, catalytic oxidation has some problems such as high cost and limited production of radicals. To improve these, in this study, a new process of O 3 /H 2 O 2 /Fe-shavings which coupled catalytic ozonation and Fenton-like oxidation with Fe-shaving wastes reused, was used in the treatment of coking wastewater secondary biochemical effluent (CWSBE). The effects of the environmental conditions on the degradation of CWSBE were studied and the response surface method was used to optimise the parameters. The performances in organic pollutant removal from CWSBE were systematically analysed by a couple of methods such as gas chromatography mass spectrometry and three-dimensional fluorescence. The results showed that macromolecular organics were degraded into small molecules pollutants after treatment by the O 3 /H 2 O 2 /Fe-shavings process. At an ozone concentration of 27.5 mg/L, with the hydrogen peroxide concentration being 10.7 mmol/L, the reaction time 60 min, the initial pH value 3.6, and the pump speed 150 rpm, the COD removal degradation efficiency was 77.5%, and the effluent COD met relevant wastewater discharge standards in China (GB 16171-2012). The mechanism research showed that·OH plays an important role in the degradation of organic pollutants.
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Molecular Catalysis
·
2025
·
IF 4.9
Bo Sheng,Huaiming Zhang,Jiarui Li,Yunlong Wang,Jinzhao Wang,Feng Zhou,Jing Zhang
Beyond efficient charge separation, the overall efficiency of H 2 O 2 photosynthesis from water and O 2 is also limited by the kinetic mismatch between the water oxidation reaction (WOR) and the oxygen reduction reaction (ORR), which leads to an insufficient proton supply and low electron transfer density. To overcome this limitation, we incorporated proton-reservoir motifs into quinone-amine polymer (QAP)-based photocatalysts, thereby alleviating the kinetic imbalance between the two half-reactions. This approach suppressed the formation of superoxide (O 2 •− ) intermediates and facilitated the direct two-electron pathway for H 2 O 2 synthesis. Our results demonstrate that hydroquinone units and specific side-chain groups, such as hydroxyl, methoxy, and methyl, play a critical role in determining the photocatalytic H 2 O 2 production performance. Notably, the hydroxyl‑functionalized QAP exhibited a 5.3-fold higher H 2 O 2 production rate compared to its methyl-substituted analogue. Moreover, under an air atmosphere rather than pure O 2 , the hydroxyl‑modified QAP maintained high H 2 O 2 productivity with no significant decline, indicating efficient utilization of low-concentration O 2 . This robustness under ambient conditions enables continuous H 2 O 2 production without the need for external gas input. Our work underscores the significance of dual proton–electron regulation in enhancing the efficiency of photocatalytic H 2 O 2 synthesis.
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ACS Omega
·
2019
·
IF 2.584
Jinjuan Xue,Zhengrong Zhu,Yuqing Zong,Chengjuan Huang,Mingxin Wang
This study investigates the degradation of dimethyl phthalate (DMP) with hydrogen peroxide and ferrate (Fe(VI)) under various reaction conditions. The results showed that the optimum conditions for dimethyl phthalate removal from water were as follows: (a) pH 7.0 and (b) the original molar ratio of [Fe(VI)]/[H2O2]/[DMP] equal to 10:2:1. Under the optimum conditions, the degradation rate of DMP can reach 89.7% in 360 min. Furthermore, 2,5-dihydroxybenzaldehyde, isophthalic acid, 2-ethylhexanol, oxalic acid, 2,6-dihydroxybenzoic acid, 2,6-dihydroxybenzaldehyde, 2,5-dihydroxybenzoic acid, and monomethyl phthalate were identified as the degradation intermediates, and degradation pathways were proposed.
研究领域:
环境化学
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水处理
·
高级氧化过程
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高影响因子
Life-Basel
·
2022
·Vol. 12
·期 9
·1436
·
IF 3.251
Ce Chen,Mingyue He,Xueting Li,Lidong Yu,Yi Liu,Yan Yang,Li Li,Jianbo Jia,Bingsheng Li
The Nrf2/ARE signaling pathway is a cell survival response pathway in response to environmental stresses. The Nrf2/ARE signaling pathway can be activated by stimulating cysteine residues at different positions in the Keap1. However, the epigenetic mechanisms of the Nrf2/ARE pathway under different stimuli are still poorly understood. In this study, we found that both hydrogen peroxide (H2O2) and Diethyl Maleate (DEM) activated the Nrf2/ARE signaling pathway at 120 hpf in zebrafish. H2O2regulated the demethylation of themaftpromoter by inhibiting the expression of methyltransferase. This promotes the mRNA expression of the Nrf2 binding factormaft, thereby promoting the downstream antioxidant genes. The methylation of the Nrf2/ARE signaling pathway was not significantly regulated by DEM. However, under oxidative stress, the methyltransferase inhibitors (decitabine and azacitidine) demethylated the promoter region ofmaft. It activated the expression of themaft, further improving the Nrf2/ARE signal pathway. At last, antioxidant target genes were activated. It was shown that H2O2and DEM cooperated with methyltransferase inhibitors, providing an important reference for the treatment of oxidative stress-related diseases and breaking new ground for the study of the mechanism of methyltransferase inhibitors in the process of tumor chemotherapy.Keywords:zebrafish;Nrf2/ARE signaling pathway;oxidative stress;methylation regulation
研究领域:
分子生物学
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毒理学
·
表观遗传学
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发育生物学
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PubMed
高影响因子
MICROCHIMICA ACTA
·
2024
·Vol. 191
·期 11
·1-9
·
IF 5.3
Wang Yueliang,Chen Xiying,Tao Zhanhui,Zhou Jingya,Sun Hanyue,Li Xian,Shi Liyu,Liu Yaqing
A novel glow-type chemiluminescence (CL)-based nanosensing system was developed for sensitive and rapid point-of-care testing (POCT) of H 2 O 2 in food. CuSe nanoparticles (CuSe NPs ) have excellent peroxidase-like activity. After being modified with thiols of 4-mercaptophenylboronic acid (MBA) (CuSe NPs @MBA), luminol can be catalyzed to produce long-lasting CL in the presence of H 2 O 2 . The possible reason for the long-lasting glow-type CL behavior was explored. Under the optimized condition, H 2 O 2 can be sensitively detected with improved repeatability. The limit of detection is as low as 0.30 μM. To meet the requirement of in situ and outside of laboratory detection, a 3D-printed portable device was designed which can eliminate the environmental interference to improve detection accuracy. The developed multifunctional platform also has the advantages of simple operation and low cost, suggesting its great potential for applications in food and agricultural fields. Graphical
研究领域:
分析化学
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食品安全
·
生物医学工程
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PubMed
高影响因子
PHYSICA SCRIPTA
·
2024
·Vol. 99
·期 8
·085914
·
IF 2.6
Yajun Xu,Qichen Zhao,Jianian Chen,Jingzhe Zhang,Binbin Xu
In recent years, graphene oxide assisted etching silicon has been considered a potential method to replace metal-assisted chemical etching. This work demonstrated the catalytic ability of graphene oxide synthesized by the Hummers method to promote chemical etching of silicon. By adjusting HF/H2O2 ratio of the solution and reaction temperature, a minimum weighted average reflectance of 9.9% in the wavelength range of 300–1100 nm was obtained. An etching rate of 10 μm h−1, faster than those in others' reports, was obtained in an optimized acidic solution at 80 °C. Finally, a four-electron model for graphene oxide assisted etching mechanism was proposed to explain our research results.
研究领域:
材料科学
·
化学工程
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ACS Applied Nano Materials
·
2024
·
IF 5.3
Chuan Jiang,Zuheng Jin,Sha Wu,Zhihong Zhu,Jiangtao Wu,Bing Su,Changzheng Hu,Laijun Liu,Liang Fang,Zhenxiang Cheng
Hydrogen peroxide (H2O2) plays a pivotal role in multiple industries, spanning healthcare, energy, chemical synthesis, and environmental protection, yet achieving its safe, ecofriendly, simple, and efficient production under ambient conditions remains challenging. In contrast to traditional piezoelectric and photocatalysis techniques, tribocatalysis has recently attracted attention owing to its mild requirements and low energy consumption. Thus, in this study, we synthesized BaxSr1–xNb2O6 (x = 0.4, 0.5, 0.6, 0.7) (BSN) ferroelectric nanopowders via solid-phase synthesis and high-energy ball milling to investigate the impact of BSN tribocatalysis on H2O2 production. Our findings reveal that H2O2 can be efficiently synthesized through a tribocatalysis pathway at room temperature and normal pressure by exerting mechanical force during physical contact between BSN particles and deionized water/O2 interfaces. This interaction induces electron transfer, leading to the generation of reactive free radicals (•OH and •O2–). Subsequently, these free radicals combine to form H2O2 (2•OH → H2O2, •O2– + e– + 2H+ → 2H2O2). Our results demonstrate that strong ferroelectric properties can enhance the catalytic capability for H2O2 production. Furthermore, the efficiency can be significantly enhanced by facilitating the passage of O2 and incorporating a sacrificial agent, resulting in a high production rate up to 952.65 μmol L–1 h–1. This study presents a new and efficient method for preparing hydrogen peroxide.
研究领域:
材料科学
·
环境科学
·
化学工程
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高影响因子
Foods
·
2026
·Vol. 15
·期 3
·595
·
IF 6
Jiaoling Wang,Hao Li,Xinxin Wu,Xindong Wang,Xinai Zhang
Considering the demand for nutritional assessment and product quality control in the tea industry, this work develops an effective electrochemical sensor based on gold nanoparticles electrodeposited onto a zeolitic imidazolate framework (Au/MOF(Zn)) for evaluating the antioxidant activity of tea subjected to microwave-assisted drying (MAD) through hydrogen peroxide (H2O2) scavenging. The MOF(Zn) enables uniform deposition of AuNPs, which significantly enhances the electrocatalytic oxidation of H2O2. The fabricated sensor exhibits a wide linear detection range from 400 μM to 1.8 mM for H2O2with a correlation coefficient of 0.9983. The experimental results demonstrate acceptable selectivity, with signal interference <5% from common tea compounds like inorganic ions, sugars, and organic acids. Electrochemical methods, including cyclic voltammetry (CV) and differential pulse voltammetry (DPV) analysis, were employed to quantify H2O2by measuring oxidation currents in phosphate-buffered saline (PBS, pH 7.0). The relative standard deviation (RSD) for repeatability and reproducibility was 5.1% and 6.8%, respectively, confirming high reliability. This sensor was successfully applied to assess antioxidant capacity in tea extracts obtained from fresh leaves subjected to microwave-assisted drying under varying power and duration. Results indicate that increasing microwave power enhances antioxidant activity, while prolonged drying at low power initially increases activity (peaking at 120 s) but reduces it upon extended exposure. Optimal antioxidant preservation was achieved at 120 s. This real-time, reliable sensing strategy offers theoretical foundations for optimizing tea processing parameters to preserve bioactive compounds, particularly polyphenols like catechins, thereby improving tea quality and health benefits.
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Sustainability
·
2026
·Vol. 18
·期 4
·1870
·
IF 4.1
Guodong Wan,Jiaqi Ding,Ruixin Zeng,Zhenbin Chen,Hua Li,Yujie Cheng,Zongping Wang,Pengchao Xie,Hongwei Zhang
Naproxen (NPX) is a widely occurring, refractory organic contaminant that cannot be removed by conventional water treatment processes. In response to the growing environmental pollution caused by NPX, an innovative and highly efficient green degradation method has been developed, designed on the principles of sustainability to promote long-term ecosystem health and advance a circular economy. In this study, using zero-valent molybdenum as a catalyst in combination with trivalent iron (Fe3+) and hydrogen peroxide (H2O2), we constructed a Mo/Fe3+/H2O2system to treat NPX-contaminated water. The effects of solution pH, H2O2concentration, Fe3+concentration, Mo dosage, and co-existing water-matrix constituents (Cl−, HCO3−, PO43−, NO3−, and humic acid (HA)) on NPX removal were investigated; reactive species were identified; and the reusability of Mo as well as its performance under the continuous-flow condition were evaluated. The results showed that the optimal pH was 3 and the appropriate Fe3+dosage is 100 µM. With 500 µM H2O2, 87.9% of NPX was removed within 7 min, and a moderate increase in Fe3+concentration, together with a suitable H2O2level, enhanced the removal efficiency. HCO3−, Cl−, and HA exerted slight inhibition, whereas PO43−markedly suppressed NPX degradation. Recycling tests and the 6 h continuous-flow treatment demonstrated excellent reusability and stability of Mo. Quenching experiments revealed that HO•and Fe(IV) were the dominant reactive species responsible for NPX degradation.
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WATER SCIENCE AND TECHNOLOGY
·
2026
·Vol. 93
·期 3
·318-331
·
IF 2.6
Wang Hanlin,Chu Ziyang,Li Mengxue,Chen Tianhu
View large Download slide View large Download slide Close modal Pyrrhotite (Fe 1-x S) was prepared by the pyrolysis of pyrite and the sulfidation of hematite, and subsequently used to activate H 2 O 2 for the degradation of tetracycline (TC). The pyrite-derived Fe 1-x S samples (P600 and P700) and the hematite-derived Fe 1-x S samples (S600, S700), prepared at 600 and 700 °C, respectively, were characterized using X-ray diffraction (XRD), X-ray photoelectronic spectroscopy (XRS), scanning electron microscopy (SEM) and magnetism analysis. The effects of annealing temperature, preparation method, and initial solution pH on TC degradation were systematically investigated. The results showed that the degradation of TC increased with the decrease in annealing temperature and initial solution pH. Quenching experiments and electron spin resonance (ESR) demonstrated that • OH and 1 O 2 were reactive oxygen species (ROSs) in acidic and alkaline media, respectively. Moreover, the sulfidation-derived pyrrhotite, featuring a monoclinic Fe 1-x S shell, exhibited superior catalytic performance than pyrolysis-derived pyrrhotite with a hexagonal Fe 1-x S shell. Notably, 1 O 2 was easier to produce in the P600/H 2 O 2 system. Both P600 and S600 maintained a high catalytic activity after five runs. These findings offer a novel approach for pyrrhotite preparation and promote the comprehensive utilization of pyrite and hematite. Pyrolytic pyrrhotite and sulfurized pyrrhotite were prepared by a one-step method. Sulfurized pyrrhotite exhibited superior catalytic activity than pyrolytic pyrrhotite. • OH was the dominant ROS under acidic conditions, while 1 O 2 prevailed under alkaline conditions. The magnetic pyrrhotite showed excellent reusability over five cycles.
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