JOURNAL OF FLUORESCENCE
·
2013
·Vol. 23
·期 5
·989-996
·
IF 1.789
Liu Shikun,Zhang Lili,Gao Jigang,Zhou Jie
A novel probe, 3′,6′ - bis(diethylamino) -2- ((2,4-dimethoxybenzylidene)amino) spiro [isoindoline-1,9′-xanthene]-3-thione (RBS), was designed and synthesized. Its structure was characterized with elemental analysis, IR spectra and 1 H NMR. The probe displayed highly selective and sensitive recognition of Hg 2+ . Reacting with mercury ions in aqueous solution, its fluorescence intensity was enhanced significantly, while its color was changed from colorless to pink. So, a new fluorescence method of detection of Hg 2+ was proposed. Its dynamic response concentration range and detection limit for Hg 2+ were 5.00 × 10 −9 M to 1.00 × 10 −6 M detected and 1.83 × 10 −9 M, respectively. Satisfying results were obtained when the probe was applied to detect spiked Hg 2+ in samples.
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ANALYTICAL CHEMISTRY
·
2017
·
IF 6.32
Shouting Zhang,Dongxu Zhang,Xuehong Zhang,Denghui Shang,Zhonghua Xue,Duoliang Shan,Xiaoquan Lu
Herein, we developed a general strategy for rapid, highly selective, and ultratrace naked-eye colorimetric detection of Hg2+ in aqueous solutions. Two dimensional rGO/PEI/Pd nanohybrids, where rGO, PEI, and Pd were referred to as reduced graphene oxide, polyethylenimine, and Pd nanoparticles, respectively, were synthesized and used as mimetic peroxidase for selective and ultrasensitive detection of Hg2+ in water and human serum samples. In the presence of mercury ions, the peroxidase mimetic activity of rGO/PEI/Pd nanohybrids was found to be stimulated and enhanced significantly, which promoted the effective oxidation and color change of 3,3′,5,5′-tetramethylbenzidine (TMB) in solution to dark blue that was detected by the naked-eye and the absorption spectroscopic method. The proposed sensing strategy coupled with spectroscopic detection method showed an ultralow detection limit of 0.39 nM for Hg2+ in ddH2O and ∼1 nM in wastewater as well as serum samples, respectively. On the basis of the colorimetric assay, a minimum concentration of ∼10 nM for Hg2+ in wastewater and human serum can be detected with the naked-eye. The naked-eye-based colorimetric assay for sensitive and selective detection of mercury is expected to hold huge potentials in applications such as environmental monitoring, clinical diagnosis, and pharmaceutical analysis.
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ELECTROCHIMICA ACTA
·
2025
·
IF 5.6
Luping Feng,Enjun Chen,Jianghong Wang,Xinfeng Li,Yujie Fan,Leyao Jin,Peisong Tang,Lixiang Zhang
A simulated sunlight-driven photoelectrochemical (PEC) sensor has been developed for quantitative analysis of hydrogen sulfide (H 2 S) with “signal-on” output by Hg 2+ -integrated ZnS nanocubes (Hg 2+ @ZnS NCs). Herein, hollow ZnS NCs were firstly prepared by the ZIF-8-derived soft-template method. Subsequently, Hg 2+ probing ions were doped into the porous structures of these ZnS NCs through an adsorption reaction, yielding Hg 2+ @ZnS NCs. It was observed that Hg 2+ @ZnS-based PEC sensor could exhibit slightly enhanced PEC responses over pristine ZnS, attributed to the adsorption of Hg 2+ on ZnS surface, which may modulate surface states/defects and band structures to suppress surface recombination. More importantly, after the addition of H 2 S, the in-situ growth of HgS@ZnS with a type-II heterojunction enables enhanced photocurrent response in developed sensor by promoting efficient spatial charge separation and transfer. A PEC sensing platform with exceptional sensitivity and selectivity has been established for H 2 S quantification, covering a linear range of 0.05–10 nM and a detection limit of 32 pM, which may serve as a guideline for the design of PEC sensors for real-world H 2 S analysis in complex matrices like environmental wastewater and industrial waste gas.
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ANALYTICA CHIMICA ACTA
·
2015
·
IF 4.513
Pei She,Yanxin Chu,Chunwei Liu,Xun Guo,Kang Zhao,Jianguo Li,Haijing Du,Xiang Zhang,Hong Wang,Anping Deng
An immunochromatographic test (ICT) strip was developed for ultrasensitive competitive immunoassay of Hg 2+ . This strategy was achieved by combining the easy-operation and rapidity of ICT with the high sensitivity of surface-enhanced Raman scattering (SERS). Monoclonal antibody (mAb) against Hg 2+ and Raman active substance 4-mercaptobenzoic acid (MBA) dual labelled gold nanoparticles (GNPs) were prepared as an immunoprobe. The Raman scattering intensity of MBA on the test line of the ICT strip was measured for quantitative determination of Hg 2+ . The ICT was able to directly detect Hg 2+ without complexing due to the specific recognition of the mAb with Hg 2+ . The IC 50 and limit of detection (LOD) of the assay for Hg 2+ detection were 0.12 ng mL −1 and 0.45 pg mL −1 , respectively. There was no cross-reactivity (CR) of the assay with other nineteen ions and the ICT strips could be kept for 5 weeks without loss of activity. The recoveries of the assay for water, human serum and urine samples spiked with Hg 2+ were in range of 88.3–107.3% with the relative standard deviations (RSD) of 1.5–9.5% (n = 3). The proposed ICT was used for the detection of Hg 2+ in urine samples collected from Occupational Disease Hospital and the results were confirmed by cold-vapor atomic fluorescence spectroscopy (CV-AFS). The assay exhibited high sensitivity, selectivity , stability, precision and accuracy, demonstrating a promising method for the detection of trace amount of Hg 2+ in environmental water samples and biological serum and urine samples.
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ACS Applied Nano Materials
·
2025
·
IF 5.5
Hanqing Liu,Yifei Zhou,Jing Xu,Le Ding,Chuan Liao,Tao Wang,Haifeng Zhou,Guangjun Zhou
High-efficiency detection of cadmium ions (Cd2+) and mercury ions (Hg2+) is crucial due to their harmful effects on the environment and human health. Here, we developed a ratiometric upconversion fluorescence (UCF)-based nanosensor by incorporating lanthanide-doped upconversion nanoparticles (UCNPs) and gold nanoparticles modified with trithiocyanuric acid (TMT-AuNPs) as specific recognition elements for the highly sensitive and selective real-time detection of Cd2+ and Hg2+. The developed nanosensor exhibited selective absorbance enhancement and UCF quenching behavior with the addition of Cd2+ and Hg2+ based on the inner filter effect (IFE). The sensitivity of the nanosensor was significantly enhanced by converting the change in absorbance into an exponential variation in UCF intensity. Therefore, the quantitative detection of Cd2+ and Hg2+ was achieved by measuring the UCF ratio I654/I540. In order to distinguish between Cd2+ and Hg2+, two biomolecules, glutathione (GSH) and ascorbic acid (AA), were used based on their different interactions with Cd2+ and Hg2+. GSH formed a specific tetrahedral complex (GSH)4Cd with Cd2+, thereby preventing Cd2+ from inducing changes in UCF intensity. In contrast, AA specifically reduced Hg2+, thereby preventing Hg2+-induced UCF changes. Thus, GSH and AA could also be detected. The limits of detection (LODs) of Cd2+, Hg2+, GSH, and AA were 2.8, 5.2, 5.1, and 7.2 nM, respectively. The designed detection platform provides a sensitive and straightforward sensing strategy for the multiplex detection of heavy metal ions and biological small molecules.
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MICROCHEMICAL JOURNAL
·
2025
·
IF 5.1
Yiji Chen,Liang He,Shirong Ai,Hang Yao,Aihua Xiong,Li Li,Jiang Li,Zhongshou Liu,Yansha Gao,Ruimei Wu,Limin Lu
Simultaneous and accurate analysis of multiple heavy metals (HMs) in environment by electrochemical method still faces huge challenges, such as complex experimental process, low detection efficiency and the interference arising from electrochemical interactions between different HMs. To address these issues, we propose a sensing platform combining S-TiO 2 @Ti 3 C 2 MXene with machine learning strategies for simultaneous electrochemical detection of Cu 2+ and Hg 2+ in water samples. Specifically, surface morphology and crystal structure of S-TiO 2 @Ti 3 C 2 were characterized via SEM, XRD, and XPS. Electrochemical behaviors were systematically investigated using cyclic voltammetry (CV) and differential pulse voltammetry (DPV). Orthogonal test-based multi-objective optimization method integrated with comprehensive balance approach were employed to determine the optimal sensing parameters, which were identified pH of 4.5, deposition time of 210 s, and deposition potential of −1.5 V. The fabricated sensor exhibited high sensitivities of 44.122 and 143.795 μA·L·mg −1 , low limits of detection of 0.392 and 0.093 μg·L −1 , and broad linear ranges of 0.001–1000 μg·L −1 for Cu 2+ and Hg 2+ , respectively. Furthermore, machine learning strategy was introduced to resolve the poor accuracy issue associated with traditional calibration curve analysis for the simultaneous detection of Cu 2+ and Hg 2+ across the entire linear range. The results indicated that minimum Redundancy Maximum Relevance (mRMR) algorithm effectively extracted valuable and critical information of Cu 2+ and Hg 2+ from the full voltammetric curves, and the constructed support vector machine (SVM) model remarkably improved detection accuracy. The reliability of the proposed SVM model was validated through simultaneous detection of HMs in actual environmental water samples, yielding favorable recovery rates.
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JOURNAL OF HAZARDOUS MATERIALS
·
2020
·
IF 9.038
Elvis Ikechukwu Nosike,Zhenqi Jiang,Lijing Miao,Ozioma Udochukwu Akakuru,Bo Yuan,Shasha Wu,Yuenan Zhang,Yujie Zhang,Aiguo Wu
This research reports a new mercury adsorbent in which Fe 3 O 4 as a core was embedded into the shell of ZIF-90 in a one-pot synthesis and the subsequent post synthesis modification (PSM) of its surface with cysteine covalently, via a Schiff’s base reaction. Poly acrylic acid (PAA) was capped on the surface of nanoparticles to prevent agglomeration of the nanoparticles. In addition, −COOH groups of PAA coordinated with Zn 2+ of ZIF-90 and this provided the platform for ZIF-90 to grow on the nanoparticles forming the core-shell structure. Based on the strong interactions between the thiol groups on the adsorbent and mercury ions as elucidated by the XPS analysis, the as-synthesized adsorbent showed selectivity for Hg 2+ . The sorbent exhibited high adsorption capacity of 900 mg g −1 towards Hg 2+ as calculated at pH 4 and the adsorption kinetics followed pseudo-second-order kinetics model better. The Hg 2+ loaded adsorbent was easily regenerated and it maintained about 70 % efficiency after the third use. Low-cost, readily available and green materials, facile preparation, efficient removal and the breakthrough in three times recyclability give the novel ZIF-90 based hybrid nanoadsorbent wide prospects in the field of environmental remediation as a good adsorbent for Hg 2+ removal in wastewater.
研究领域:
环境科学
·
材料科学
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JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY
·
2017
·Vol. 55
·期 6
·1067-1076
·
IF 2.952
Dalong Zhai,Wei Shi,Yonghai Hui,Zhengfeng Xie
High-efficiency, mild-conditioned tandem Knoevenagel–Michael reaction was utilized to post-modify aldehyde-containing, triphenylamine-based precursor conjugated polymer ( CP1 ) to afford dimedone-decorated aimed polymer ( CP2) . The chemical structure of CP2 was verified by FTIR and 1 H NMR analyses. With the introduction of aqueous Hg 2+ , fluorescence of CP2 in THF-water mixture ( V THF / V water = 1/100) (buffered with 5 mM sodium dihydrogen phosphate-disodium hydrogen phosphate (PB), pH = 7.4) altered significantly, with the emission changed from blue to orange. Besides this, CP2 also displayed specific optical response to ClO − in another probing medium ( V THF / V water = 1/100, buffered with 50 mM PBS (with NaCl in PB, pH = 7.4). The detailed probing process and the plausible detection mechanism of CP2 to Hg 2+ and ClO − were systematically investigated here. © 2017 Wiley Periodicals, Inc. J. Polym. Sci., Part A: Polym. Chem. 2017 , 55 , 1067–1076
研究领域:
高分子化学
·
材料科学
·
分析化学
·
环境监测
·
光学传感
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TALANTA
·
2026
·
IF 6.7
Tao Li,Weitao Wang,Boyang Dou,Shudie Shen,Wenli Zhao,Yanfei Wang,Xiaoyu Zhao,Botao Teng,Liang Zhu
The development of portable, sensitive, and interference-resistant platforms for on-site Hg 2+ detection in aquatic food samples remains highly desirable for food safety monitoring. Herein, a smartphone-assisted fluorescence/colorimetric dual-mode sensing platform was constructed based on N-doped carbonized polymer dots (N-CPDs). The N-CPDs were prepared from ethylenediaminetetraacetic acid and m -phenylenediamine via one-step crosslinking polymerization. By regulating surface O/N active sites and local conjugated structures, the N-CPDs exhibited fluorescence quenching and colorimetric responses toward Hg 2+ without additional responsive reagents. The limits of detection were 40.91 and 38.97 nM for the fluorescence and colorimetric modes, respectively. Structural characterization and quantum chemical calculations indicated that the matching between key oxygen-containing recognition sites and local conjugated structures is critical to the sensing performance. Mechanistic analysis further revealed Hg 2+ -induced static fluorescence quenching and a coordination-driven colorimetric response. Coupled with smartphone-based RGB analysis, the platform enabled portable quantitative detection of Hg 2+ in aquatic food samples, including fish, shrimp, crab, and seaweed. The recoveries were 90.11–108.88%, with RSDs below 4.98%, and the results agreed well with ICP-OES measurements. This work provides an effective strategy for constructing high-performance CPD-based dual-mode sensing platforms and offers a promising tool for portable and reliable Hg 2+ monitoring in real food samples.
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MICROCHEMICAL JOURNAL
·
2026
·
IF 5.2
Kai Hu,Wuliji Hasi,Guoqiang Fang,Siqingaowa Han
Cinnabar, with low water solubility and poor oral absorption, poses challenges in toxicity assessment. Relying solely on total mercury leads to overestimation, making detection of soluble Hg 2+ essential. This study presents a surface-enhanced Raman scattering (SERS) strategy using Au concave nanocubes (Au CNC) modified with 3-mercaptopropionic acid (3-MPA) and 4-mercaptopyridine (4-MPY), combined with a data-augmented convolutional neural network-partial least squares regression (CNN-PLS) model, for quantifying soluble Hg 2+ in cinnabar and its preparations. 3-MPA binds Hg 2+ , inducing Au CNC aggregation and enhances the SERS signal, while 4-MPY improves sensitivity. To overcome insufficient data in practical, data augmentation was used to expand the SERS dataset, and the performance of CNN, PLS, and CNN-PLS models was compared before and after augmentation. The results indicate that the data-augmented CNN-PLS model performed best, with a coefficient of determination (R 2 ) of 0.999 in the range of 0.001–1 μg/mL and a Mean Squared Error of Prediction (MSEP) of 0.0001. This method was applied to quantify Hg 2+ leaching from cinnabar and four cinnabar-containing preparations after 12 h of immersion in artificial gastric juice. The mean Hg 2+ concentrations from three cinnabar batches were 0.691, 0.557, and 0.546 μg/mL, while for the preparations, the concentrations were 0.085, 0.047, 0.038, and 0.023 μg/mL. These results showed excellent agreement with atomic fluorescence spectrometry (AFS), confirming the method's reliability and accuracy. This simple, accurate, and safe approach offers a novel solution for mercury safety assessment in cinnabar and its preparations, with significant potential for traditional Chinese medicine safety evaluation and environmental monitoring.
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SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2025
·
IF 4.6
Zhuoying Li,Linan Zhou,Fang Zhang,Huiyi Yang,Lihua Guo,Fang Chai
Heavy metals adversely affect the environment, ecosystems, and human health. The effective detection and treatment of heavy metals has become a major global concern. Herein, calcium and nitrogen co-doped carbon dots (E-CDs) were developed using cheap kitchen waste eggshells as precursors, and utilized as dual-mode fluorimetric/colorimetric sensor for the multivariate detection of Hg 2+ and Ag + . The E-CDs exhibited yellow emission at 420 nm excited at 567 nm, with a quantum yield of 15.49% and lifetime of 12.92 μs. The multivariate detection of Hg 2+ and Ag + can be achieved selectively by distinguishing via dual-mode respectively. The limit of detection (LOD) for Hg 2+ reached 11.28 nM, while the Ag + can be determined by fluorimetric/colorimetric dual-mode with LODs of 128.23 nM and 1.02 μM, respectively. Remarkably, the E-CDs integrated with a smartphone-based paper sensor supported by RGB analysis achieved the detection of Hg 2+ and Ag + with LODs of 56.2 nM and 90.96 nM, respectively. Notably, the recoveries in real samples attained 96.3–105.7% with excellent environmental tolerance. Furthermore, a logic gate circuit was developed to support the potential practical intelligent application. This work highlighted a cost-effective, multi-functional sensing strategy with significant potential for monitoring heavy metal contaminants in environmental and food safety applications.
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SENSORS AND ACTUATORS B-CHEMICAL
·
2020
·
IF 7.1
Hui Liu,Jinshui Wang,Huali Jin,Min Wei,Wenjie Ren,Yurong Zhang,Ligen Wu,Baoshan He
A sensitive electrochemical biosensor was constructed for Hg 2+ detection based on peonylike Cu-MOFs in situ growth of PtPd NPs bimetallic label S 1 and Mg 2+ -dependent DNAzyme-driven DNA Walker dual amplification signal strategy. The hairpin DNA (HP) and signal label [email protected] NPs/S 1 were first used to self-assemble on the gold nanorods/poly (diallyldimethylammonium chloride) functionalized graphene (AuNRs/PDDA-Gr) modified electrode, at this time, Cu ions can undergo a valence change to produce a larger initial signal. Here, we designed S 2 that can perform dual functions and contains two sequences, on was a substrate sequence of the Mg 2+ -dependent DNAzyme and the other was a sequence complementary to HP. In the presence of target Hg 2+ , HP was opened and hybridized with enzymatically sequenced DNA Walker (S 2 ) to preferentially form thymine-Hg 2+ -thymine (T-Hg 2+ -T). Then, DNA Walker exhibited catalytic activity of DNAzyme in the presence of Mg 2+ to continuously cleave [email protected] NPs/S 1 , resulting in a decrease of electrochemical signal. Under optimal conditions, the change of current was linearly related to the negative logarithm of the Hg 2+ concentration in the detection range of 0.001–100 nM with a low detection limit of 0.52 pM. Moreover, the proposed aptasensor was successfully applied in detection of milk powder samples.
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