INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2023
·
IF 8.2
Qin Geng,David Julian McClements,Zhihua Wu,Ti Li,Xuemei He,Xixiang Shuai,Chengmei Liu,Taotao Dai
Procyanidins are bioactive polyphenols that have a strong affinity to proteins. Beta-lactoglobulin (BLG) is widely used as an emulsifier in the food and other industries. This study evaluated the interaction between BLG and A-type procyanidin dimer (PA2) using the spectroscopic, thermodynamic, and molecular simulation. PA2 decreased the transmissivity and quenched the intrinsic fluorescence of BLG, suggesting that the two molecules formed a complex. The binding of PA2 reduced the surface hydrophobicity and altered the conformation of BLG with increasing the random coil regions. Thermodynamic and isothermal titration calorimetry analyses suggested that the main driving force of PA2-BLG interaction was hydrophobic attraction. Molecular docking simulations were used to identify the main interaction sites and forces in the BLG-PA2 complexes, which again indicated that hydrophobic interactions dominated. In addition, the influence of PA2 on the ability of BLG to form and stabilize O/W emulsions was analyzed. Emulsions formulated using BLG-PA2 complexes contained relatively small droplets (D 4,3 ≈ 0.7 μm) and high surface potentials (absolute value >50 mV). Compared to BLG alone, BLG-PA2 complexes improved the storage stability of the emulsions. This study provides valuable new insights into the formation, properties, and application of protein-polyphenol complexes as functional ingredients in foods.
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高影响因子
Nanomaterials
·
2023
·Vol. 13
·期 7
·1188
·
IF 5.3
Lina Sun,Liping Sun,Lihua Huo,Hui Zhao
H2O2generation via an electrochemical two-electron oxygen reduction (2e−ORR) is a potential candidate to replace the industrial anthraquinone process. In this study, porous carbon catalysts co-doped by nitrogen and oxygen are successfully synthesized by the pyrolysis and oxidation of a ZIF-67 precursor. The catalyst exhibits a selectivity of ~83.1% for 2e−ORR, with the electron-transferring number approaching 2.33, and generation rate of 2909.79 mmol g−1h−1at 0.36 V (vs. RHE) in KOH solution (0.1 M). The results prove that graphitic N and –COOH functional groups act as the catalytic centers for this reaction, and the two functional groups work together to greatly enhance the performance of 2e−ORR. In addition, the introduction of the –COOH functional group increases the hydrophilicity and the zeta potential of the carbon materials, which also promotes the 2e−ORR. The study provides a new understanding of the production of H2O2by electrocatalytic oxygen reduction with MOF-derived carbon catalysts.Keywords:porous carbon;two-electron reduction of oxygen;hydrogen peroxide;electrocatalyst
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高影响因子
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
·
2023
·Vol. 415
·期 8
·1545-1557
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IF 4.3
Ding Minling,Niu Huizhe,Guan Ping,Hu Xiaoling
A sensitive and selective molecularly imprinted polymer (MIP) sensor was developed for the determination of amyloid-β (1–42) (Aβ 42 ). The glassy carbon electrode (GCE) was successively modified with electrochemical reduction graphene oxide (ERG) and poly(thionine-methylene blue) (PTH-MB). The MIPs were synthesized by electropolymerization with Aβ 42 as a template and o-phenylenediamine (o–PD) and hydroquinone (HQ) as functional monomers. Cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS), chronoamperometry (CC), and differential pulse voltammetry (DPV) were used to study the preparation process of the MIP sensor. The preparation conditions of the sensor were investigated in detail. In optimal experimental conditions, the response current of the sensor was linear in the range of 0.12–10 μg mL −1 with a detection limit of 0.018 ng mL −1 . The MIP-based sensor successfully detected Aβ 42 in commercial fetal bovine serum (cFBS) and artificial cerebrospinal fluid (aCSF).
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高影响因子
INORGANIC CHEMISTRY COMMUNICATIONS
·
2023
·
IF 3.8
Xin Yan,Chaoli Wang,Tao Ai,Zhuo Li,Yanhui Niu
The porous (Co 0.2 Cu 0.2 Mg 0.2 Ni 0.2 Zn 0.2 )O high entropy oxide was synthesized by a facile solution combustion method. The X-ray diffraction (XRD) patterns showed that a rock-salt phase (Co 0.2 Cu 0.2 Mg 0.2 Ni 0.2 Zn 0.2 )O nanocrystalline was successfully constructed after heat treatment above 800 °C. A porous microstructure with high specific surface area was determined by scanning electron microscope (SEM) and N 2 adsorption analysis, respectively. The (Co 0.2 Cu 0.2 Mg 0.2 Ni 0.2 Zn 0.2 )O high entropy oxide displayed excellent peroxymonosulfate (PMS) activation which could fully degrade the tetracycline (TC) within 24 min. Moreover, the effect of PMS concentration, the high entropy oxide dosage, pH value, temperature and coexisting anions on the degradation efficiency of TC was systematically studied. According to free radical quenching experiments and electron paramagnetic resonance studies, the possible mechanism of TC degradation over the (Co 0.2 Cu 0.2 Mg 0.2 Ni 0.2 Zn 0.2 )O/PMS system was proposed. This work provided a research basis for the use of high entropy oxide for PMS activation in environmental treatment.
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JOURNAL OF APPLIED POLYMER SCIENCE
·
2023
·Vol. 140
·期 10
·e53590
·
IF 3
Sisi Yuan,Yongjun Wang,Xiujun Wang,Donghua Liao,Ming Duan,Shenwen Fang
The block polyether demulsifier prepared by ring-opening polymerization of ethylene oxide and propylene oxide under high temperature and high pressure is the most widely used demulsifier for water in crude oil emulsion. It has the high synthesis risk and cost. Therefore, the development of non-block polyether demulsifier has attracted more and more attention. In this article, a new type of demulsifier was sythesized by radical polymerization of acrylate and cationic monomer. It was found that the copolymer PMA-co-PDBC of methyl acrylate (MA) and benzyldimethyl [2-[(1-oxoallyl)oxy] ethyl] ammonium chloride (DBC) synthesized in the mixed solvent of dipropylene glycol methyl ether and water had a good performance. When dosage of PMA-co-PDBC was 200 mg/L, the dehydration rate of water in crude oil emulsion with 50% water content can reach 80% at 80°C within 4 h. Structural and interface properties analysis presented that PMA-co-PDBC had a microblock structure similar with block polyether and it can effectively reduce the strength of W/O interfacial film to realize the demulsification. Although the demulsification performance of PMA-co-PDBC was not better than block polyether, its preparation safety and cost are much better. The results of this article can provide a new option for the development of crude oil demulsifier.
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高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
·
2023
·Vol. 140
·期 10
·e53594
·
IF 3
Zejun Zhang,Fan Ye,Guosheng Ai,Huanyu Liu,Guanxin Zeng,Liwei Shen,Ying Yang,Huaikui Yuan,Xuening Feng,Yuanzhu Mi
A highly branched PNDC demulsifier with 2,6-naphthalenedicarboxylate as centronucleus was prepared by an efficient “one-pot” strategy. The product was characterized by FT-IR, 1 H-NMR, and TGA. The bottle test was performed to explore the effect of temperature, settling time, pH value, and concentration on the demulsification efficiency (DE). The DE reached an optimal value of 94.63% when the concentration of PNDC, settling time and operated temperature were 100 mg/L, 60 min and 70°C, respectively. Also, the DE could reach 91.58% when the concentration was only 20 mg/L at the same conditions. It showed that PNDC had an excellent performance in W/O emulsions with an extremely low concentration. Especially, PNDC could be used over a wide pH range (4–12) and high salinities, indicating that it had a good salt, acid and alkaline tolerance. In addition, the interfacial tension (IFT), surface tension (SFT), elastic modulus and micrograph analysis were carried out to investigate the possible mechanism. This work provides a highly branched demulsifier with high DE for the demulsification of stable W/O emulsions.
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高影响因子
INTEGRATED FERROELECTRICS
·
2019
·
IF 0.486
Liping Zhou,Hao Hu,Yi-Xin Zhang,Qing-Ye Meng,Bing Yu,You-Qing Shen,Hai-Lin Cong
Dendrimers have become effective drug carriers and gene transfection vectors for medical biomaterials. In this experiment, UCNPs (NaGdF4:Tm, Yb@NaGdF4) and three-generation PAMAM dendrimers were prepared firstly; then NaGdF4:Tm, Yb@NaGdF4 was modified by Polyacrylic acid(PAA); PAMAM were grafted to the surface of the modified UCNPs by the reaction between amino groups and carboxyl groups; finally, O-nitrobenzaldehyde was grafted to the surface by Schiff base reaction.The synthesized upconversion materials were coated with PAA and PAMAM, then loaded with O-nitrobenzaldehyde to form spherical nanoparticles. The particle size of prepared nanoparticles is 75 ∼ 80 nm. The dendrimer complex can emit ultraviolet light to regulate the pH gradient of aqueous solution under the excitation of near-infrared light (980 nm), and can be used to kill cancer cells by changing the acidity of tissue cells; secondly, the cavity between dendrimers and dendrimers on the surface of the complex can be used in many fields such as drug delivery and gene transfection; the nanoparticles provide a new method for cancer treatment.
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ACS Applied Bio Materials
·
2019
·
IF 0
Yanping Tong,Zhaochuang Wang,Yan Xiao,Wei Liu,Jinghao Pan,Yan Zhou,Meidong Lang
The emerging tide of hydrogels in biomedical fields drives them to possess good biocompatibility, tunable mechanical properties, and fast gelation process. Herein, a composite hydrogel containing copolypept(o)ides and functional polysaccharides was constructed through dynamic acylhydrazone linkages. First, a series of peptide–peptoid copolymers were synthesized by ring-opening polymerization of sarcosine (Sar) and l-glutamic acid γ-benzyl ester (BLG) N-carboxyanhydrides (NCAs). The benzyl groups of BLG units were substituted with hydrazide groups through ester–amide exchange aminolysis reaction. The statistical copolymer of poly(sarcosine-co-glutamate-hydrazide) (P(Sar-co-GH)) was chosen as an optimized precursor due to its excellent water solubility and gel-forming ability with aldehyde-modified sodium alginate (OSA). Moreover, cellulose nanocrystals (CNCs) were prepared as nanofillers to reinforce the P(Sar-co-GH)-OSA hydrogel. We demonstrated that the copolymer sequences and composition contents made a difference to the properties of the formed hydrogels by variation of the cross-linking density. The dynamic acylhydrazone bonds endowed hydrogels with pH responsiveness and reversible networks. The NIH/3T3 cells encapsulated in the hydrogels maintained high viability and proliferation abilities, indicating that the nanocomposite hydrogels could be explored to fabricate a customized responsive drug delivery system or cell scaffolds for tissue engineering.
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ACS Applied Bio Materials
·
2018
·
IF 0
Xingzhong Zhang,Yixiang Wang,Xiaogang Luo,Ang Lu,Yan Li,Bin Li,Shilin Liu
The increased quantities of fat in plants could allow the cells to inhibit the growth of ice and thus prevent the damages of their tissue structure in winter. In view of the structural buildup of freezing tolerance mechanism, here we presented a facile way of employing O/W Pickering emulsion as a template to produce the freestanding organo-hydrogels with increased mechanical stability and energy storage capacity. The oil droplets stabilized by cellulose nanofibrils were dispersed in the alginate polymer network that cross-linked with Ca2+, which resulted in homogeneous and closely packed microstructures. The prepared organo-hydrogels could maintain original gel structure under frozen conditions and had extraordinary mechanical performance. It could endure compressive stress up to 35 KPa (at 50% strain) and the elastic modulus was around 72 KPa, while the solid content of polysaccharides was only about 0.75%. By using our comprehensive strategy, organo-hydrogels with higher volumes of oil phase exhibited an enhanced cold storage capacity. For alginate hydrogel, it took 8 min when the temperature rose from 0 to 5 °C, while for the organo-hydrogel with oil volume of 30%, it took about 24 min. After 34 min, the inner temperature of alginate hydrogel was close to 25 °C, and about 70 min were needed for the temperature of organo-hydrogel to reach 25 °C. This kind of gel materials with complementary heteronetworks not only will have potential applications in cold chain logistics, but also can be applied in other fields with unusual functions.
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FOOD HYDROCOLLOIDS
·
2019
·
IF 5.839
Qi Li,Bing Xie,Yixiang Wang,Yanting Wang,Liangcai Peng,Yan Li,Bin Li,Shilin Liu
For high value utilization of energy crops, in this work, a high stable O/W Pickering emulsion had been prepared successfully by using cellulose nanofibrils (CNFs) obtained from Miscanthus floridulus straw (MFS). The effect of high pressure homogenization time on the physicochemical properties of the resulted CNFs had been investigated. The obtained CNFs had high surface activity and could spontaneously diffuse to the interface of the O/W phase. The particle adsorption kinetics of CNFs was characteristic of soft particles or Pickering emulsifiers, and the adsorption was irreversible. Therefore, stable oil-in-water Pickering emulsion was obtained by using the CNFs as particle emulsifiers, and the emulsion stabilized by CNFs with only 0.15 wt% exhibited outstanding stability. Moreover, the environmental factors, such as pH values, ionic strength, and temperature had little influence on the stability of the emulsion. All the results indicated that CNFs exhibited promising interfacial activity and powerful emulsifying ability. Owing to the flexible shape of the CNFs, it was concluded that MFS as a kind of energy crop was a promising source to obtain the CNFs for the fabrication of novel food-grade Pickering emulsions.
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RSC Advances
·
2019
·Vol. 9
·期 24
·13458-13464
·
IF 3.049
Hao Guo,Mingyue Wang,Rui Xue,Jing Yao,Xuejiao Wang,Longwen Zhang,Jianfeng Liu,Wu Yang
A new COF (NWNU-COF-4) linked by an aryl ether bond (Ar–O–Ar) was synthesized by the condensation reaction of 2,4,6-trihydroxypyrimidine and trinitrophenol under simple and easy reaction conditions. Fourier transform infrared spectroscopy (FT-IR), X-ray photoelectron spectroscopy (XPS), N2 adsorption–desorption, thermogravimetric analysis (TGA), powder X-ray diffraction (XRD) and scanning electron microscopy (SEM) were utilized to characterize the product. The BET specific surface area of NWNU-COF-4 was 21.33 m2 g−1, and its pore size was about 1.351 nm. Additionally, this method of preparation was simple and cheap. The electrochemical measurements showed that the synthesized NWNU-COF-4 had excellent pseudocapacitive performance with maximum specific capacitance of 133.44 F g−1 at 0.3 A g−1 in 6 mol L−1 KOH electrolyte. When the current density increased by 10 times (3.0 A g−1), the specific capacitance was 114.12 F g−1, and the retention rate was 82%. After 10 000 GCD cycles, the capacitance still kept 94% of its initial capacitance.
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ACS Applied Materials & Interfaces
·
2019
·
IF 8.456
Hejia Sun,Hui Zheng,Qiming Tang,Yuman Dong,Fengmei Qu,Yaolei Wang,Guang Yang,Tao Meng
A simple process is developed for the one-step preparation of dual-compartment alginate microcapsules with controlled size and structure from microfluid-generated water-in-water-in-oil (W/W/O) emulsion droplet. Unlike other methods that rely on transient W/W/O emulsion droplet, we introduce an aqueous two-phase system (ATPS) to form a stable W/W/O emulsion droplet as a template for preparing dual-compartment alginate microcapsules. Two different bioactive molecules are able to be spatially confined encapsulated in the shell and core of alginate microcapsules due to the partitioning effect of ATPS and the high viscosity of alginate solution. Moreover, an enzyme cascade reaction with a spatial confined glucose oxidase and horseradish peroxidase in the shell and core of alginate microcapsules confirms its excellent biocompatibility and high activity. This method provides a green platform for enzyme-catalyzed tandem reactions and controlled sequential release of multiple drugs based on alginate microcapsules.
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高影响因子
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