JOURNAL OF RAMAN SPECTROSCOPY
·
2013
·Vol. 44
·期 8
·1136-1143
·
IF 2.679
Chenglong Hu,Shaoyun Chen,Weihong Zhang,Fangyan Xie,Jian Chen,Xudong Chen
The surface chain geometry of atactic poly (methyl methacrylate) (a-PMMA) film and nanosphere (NS) was revealed by surface-enhanced Raman scattering (SERS) spectra. The Ag nanoparticles and nanoplates were prepared by electrochemical deposition and chemical synthesis for SERS substrates. The experimental results suggested that the molecular chain axis of a-PMMA film adopted a trans-conformation on bonding to Ag surface ascribed to the short-range chemical (CHEM) effect according to the SERS selection rules. However, for the well-coated monolayer of a-PMMA NSs, the α-CH 3 in polymer chains stood vertically to the Ag surface due to the giant local electromagnetic effect, then the chain conformation presented in the interface between a-PMMA NSs and Ag metal was adopted the opposite orientation compared with a-PMMA film. The Raman enhancement of the Ag nanoparticles was more prominent than that of the Ag nanoplates due to the free energies of face-centered cubic crystal faces in nanoparticles, but the single crystals with (111) plane of Ag nanoplates could improve the stability of SERS signals when the annealed temperature was above T g of a-PMMA NSs. The present work can provide some useful information of surface chain geometry and conformation of NSs for designing various materials with well-defined structure via a-PMMA NSs template. Copyright © 2013 John Wiley & Sons, Ltd.
研究领域:
材料科学
·
光谱学
✓ 已验证
DOI
高影响因子
RSC Advances
·
2015
·Vol. 5
·期 50
·39697-39704
·
IF 3.84
Ya-Guang He,Sheng-Yu Shi,Na Liu,Yuan-Yuan Zhu,Yun-Sheng Ding,Jun Yin,Zong-Quan Wu
We report a new type of functional composite films by taking advantage of the interface-directed assembly between thiol groups functionalized poly(4-isocyano benzoic acid⋯pyridine-4-thiol)-b-poly(3-hexylthiophene) (PPI(–SH)-b-P3HT) conjugated copolymers and gold nanoparticles (Au NPs) at the chloroform/water interface. The PPI(–SH)-b-P3HT copolymers were synthesized through hydrogen bonding induced micellization and subsequent thiol–disulfide exchange reaction. Transmission electron microscopic (TEM) and atomic force microscopy (AFM) observations showed the film was uniform on a large scale and the integrity of surface morphology was not affected by the Au NPs concentration. Interestingly, the film substrate not only exhibited a strongly Au NPs concentration dependent surface-enhanced Raman scattering (SERS) activity but also allowed detection of model molecule, IR-792 perchlorate (IR-792), in the SERS measurement. This proof-of-concept suggests the interfacial assembly route is effective in integrating the properties of organic polymers and inorganic nanoparticles, and for further application.
研究领域:
材料科学
·
纳米技术
·
光谱学
✓ 已验证
DOI
高影响因子
ANALYST
·
2019
·Vol. 144
·期 22
·6698-6705
·
IF 4.019
Xuegang Gong,Xiaoyong Liao,You Li,Hongying Cao,Yishu Zhao,Haonan Li,Daniel P. Cassidy
A simple surface-enhanced Raman spectroscopy (SERS) sensor based on an undecorated gold-colloid substrate was developed for the rapid and effective detection of polycyclic aromatic hydrocarbons (PAH). The SERS enhancement of the bare Au nanoparticles for PAH was achieved by adjusting chemical reduction conditions and Cl− content. The strongest SERS response of this system was achieved with 2.0 mL of trisodium citrate (1%) and 80 μL of NaCl (1 M). With this simple SERS sensor, qualitative and quantitative determination of trace-level naphthalene (NaP), phenanthrene (PHE) and pyrene (PYR) were achieved using a portable Raman spectrometer at detection limits of 1.38 μg L−1, 0.23 μg L−1, and 0.45 μg L−1, respectively. Plots of SERS intensity vs. PAH concentrations were linear, with correlation coefficients (R2) ranging from 0.8729 to 0.9994. More importantly, the SERS sensor was able to accurately identify each PAH in complex mixtures. This SERS technique shows great promise for the rapid and direct detection of aromatic hydrocarbons organic pollutants in field.
研究领域:
环境科学
·
分析化学
✓ 已验证
DOI
高影响因子
TALANTA
·
2026
·
IF 6.7
Heshuang Dong,Junhao Li,Xiaorui Jiang,Xiang Li,Haipeng Liu,Cunliang Yang,Zhiheng Yu,Yufeng Ma,Ke Wang,Jingjing Wang,Zhi Jiang,Jijun Feng
Surface-Enhanced Raman Scattering (SERS) has emerged as a powerful analytical technique due to its exceptional molecular specificity and ultra-high sensitivity. However, conventional SERS substrates are challenged by spatial inhomogeneity of hotspots and low light-collection efficiency. A highly sensitive tapered Fiber SERS probe is thus developed, which can enable remote and in-situ detection with an improved reproducibility. Tapered fibers with precisely controllable cone angles were fabricated by chemical etching. Monodisperse silver nanocubes (Ag NCs) were then decorated onto their silanized surfaces through electrostatic assembly. Ag NC generates approximately threefold stronger local electric fields compared to conventional nanospheres under 532-nm laser excitation as revealed by finite-difference time-domain simulations, and there are more obvious electromagnetic hotspots at the particle gaps of the Ag NCs (112 V/m). Experimentally, the probe can achieve a limit of detection of 10 −9 M for crystal violet with an enhancement factor of 3.91 × 10 6 , and exhibits excellent spectral reproducibility and temporal stability. Ultrasensitive detection of levofloxacin residues in milk can be further realized with the presented silver nanocubes-enhanced tapered fiber SERS probe, which can provide a highly sensitive in-situ SERS platform for environmental monitoring, biomedical diagnostics, food-safety, and so on.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ACS Omega
·
2026
·
IF 4.3
Yuxuan Chen,Ruipeng Chen,Hui Wang,Dongxia Pan,Mengting Zhou,Liang Yang,Zhen Ma,Fan Zhang,Jiawen Zhao,Xiangfang Tang,Benhai Xiong
Aflatoxin B1 (AFB1), a highly carcinogenic mycotoxin, poses significant threats to feed safety and human health, even at trace levels. To address the demand for trace detection of AFB1, we proposed a surface-enhanced Raman scattering (SERS) sensor based on photonic crystal microspheres (PCMs) for a wide-range and ultrasensitive quantitative detection of AFB1. This sensor employed SERS nanotags of gold–silver core–shell nanostars embedded with Raman reporter molecules as the enhancement substrate. Its surface protrusions can generate strong plasmon resonance, which further forms extremely intense “hot spots”─a structural feature that renders it significantly superior to spherical nanoparticles in trace detection. Experimental results demonstrate that the developed sensor exhibits an excellent detection performance. Furthermore, benefiting from the unique structural color of PCMs, the sensor is capable of detecting trace amounts of AFB1 in complex matrices. The limit of detection (LOD) reached 0.988 pg/mL, and the linear dynamic range (LDR) was from 1 pg/mL to 100 ng/mL. Additionally, the sensor exhibits excellent specificity, reproducibility, and stability. After 14 days of storage, the sample retained 89.2% of its initial performance. In practical applications, it showed good consistency with commercial enzyme-linked immunosorbent assay (ELISA) kits. All of these results demonstrate that the proposed method has great potential for trace detection and is expected to provide a novel integrated analytical platform with low background, high sensitivity, and a wide detection range for feed safety monitoring.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ANALYST
·
2015
·Vol. 140
·期 23
·7934-7938
·
IF 4.107
Hai-Xin Gu,Da-Wei Li,Lin Xue,Yong-Feng Zhang,Yi-Tao Long
We presented a facile method for the preparation of a portable detection column integrated with silver nanoparticle (Ag NP) functionalized glass fibers for surface-enhanced Raman scattering (SERS). Ag NPs were immobilized onto the surface of fibers through a two-step self-assembly process, and the cycling of the assembly process was repeated to optimize the SERS activity. The optimized fibers coated with homogeneous and dense Ag NPs were combined with a glass column, displaying good reproducibility. This combination could construct more “hot spots” and the spatial intra-channel structure for high mass transfer, and provide more sufficient interactions between the probing laser and metallic nanoparticles. The capability of the prepared column to have high sensitivity to dyes was demonstrated by the measurements of rhodamine 6G, alizarin red and methyl orange, with low concentrations of 28 pM, 64 pM and 0.36 nM, respectively. The SERS-active column fabricated by a facile, low-cost and high-yield approach is expected to be an effective and practical means for on-site application when rapid separation and detection of analytes in the liquid sample is needed.
研究领域:
分析化学
·
纳米生物技术
·
生物传感器
·
环境监测
·
分子诊断
✓ 已验证
DOI
高影响因子
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
·
2023
·Vol. 415
·期 9
·1699-1707
·
IF 4.3
Peng Shirun,Lu Dechan,Zhang Bohan,You Ruiyun,Chen Jingbo,Xu Huiyao,Lu Yudong
Liquid biopsies have significance for early colon cancer screening and improving patient survival. Recently, several researchers have applied surface-enhanced Raman spectroscopy (SERS) for the label-free and non-invasive detection of serum. Most of these studies performed the assay using a mixture of noble metal nanoparticles (NMNPs) with serum. However, SERS analysis of serum remains a challenge in terms of reproducibility and stability, as NMNPs tend to aggregate when mixed with serum, resulting in a non-uniform distribution of hot spots. Here, we report on the non-invasive identification of colon cancer (CC) using an internal standard (IS)–calibrated label-free serum SERS assay in combination with machine learning. Serum SERS spectra of 50 CC patients and 50 health volunteers have been obtained using silver nanoparticle (Ag NP) colloid and mercaptopropionic acid–modified Ag NPs (Ag NPs–MPA) as the SERS substrates. Decision tree (DT), random forest (RF), and principal component and linear discriminant analysis (PCA–LDA) algorithms were utilized to establish the diagnosis model for SERS spectra data classifying. The results show that the RF model provides a high diagnostic accuracy compared to PCA–LDA. Following calibration with IS molecules, high diagnostic accuracy of over 90% and 100% specificity can be achieved with DT, RF, and PCA–LDA algorithms to differentiate between cancer and normal groups. The results from this exploratory work demonstrate that serum SERS detection combined with multivariate statistical methods and IS calibration has great potential for the non-invasive and label-free detection of CC.
研究领域:
生物医学工程
·
分析化学
·
机器学习
·
癌症诊断
·
纳米技术
✓ 已验证
DOI
高影响因子
ACTA PHYSICO-CHIMICA SINICA
·
2013
·Vol. 29
·期 12
·2599-2607
·
IF 0.869
LIU Wen-Han,YUAN Rong-Hui,TENG Yuan-Jie,MA Chun-An
Amonolayer film of thiosalicylic acid (TSA) adsorbed on activated gold electrodes was investigated by using in situ electrochemical surface-enhanced Raman scattering (EC-SERS). In the SERS spectra of selfassembled monolayers in solutions with different pH values, two peaks with
Raman intensities that decreased with increasing pH were observed. The optimum EC-SERS signals were obtained at 0.7 V and 70 s, and it was found that the intensities became weaker, and the peaks eventually disappeared, when the potential was negatively shifted. This showed that the alignments
of TSA assembled on the gold surface changed in response to changes in the external conditions. The absorption mechanism of the TSA monolayer was investigated by calculating the distribution fraction of TSA at different pH values and the enhancement factor (EF) at different potentials, using
a combination of SERS and EC-SERS. As a result of different electrochemical absorption orientations of TSA and its reduction/desorption behavior at high negative potentials, the Raman enhanced effect of TSA on gold was significantly reduced and the SERS activity was irreversibly lost.
研究领域:
分析化学
·
电化学
·
表面科学
·
光谱学
·
纳米材料
✓ 已验证
DOI
高影响因子
NANO
·
2013
·
IF 1.167
JING XIONG,QUNJI XUE,XUEDONG WU
Water-soluble and stable dispersions of silver nanoparticles (Ag NPs) were obtained using a straightforward one-step synthesis method. Polyacrylamide (PAM), a kind of water-soluble polymer with polar amide group, is used as stabilizing agent to prevent the aggregation of Ag NPs in aqueous medium. The successful formation of PAM-stabilized Ag NPs was demonstrated by ultraviolet-visible spectroscopy (UV-Vis), transmission electron microscopy (TEM), X-ray photoelectron spectroscopy (XPS) and Fourier-transform infrared spectroscopy (FTIR). In addition, the SERS-active substrate made of Ag NPs was fabricated to enhance the Raman signal of R6G and graphene. The significant SERS effective makes the as-synthesized substrate to be widely used in practical applications for routine SERS analysis and water environment biological monitoring.
研究领域:
纳米材料
·
分析化学
·
光谱学
·
环境监测
·
纳米技术
✓ 已验证
DOI
高影响因子
ACS Applied Materials & Interfaces
·
2022
·
IF 10.383
Yunjia Wei,Qi Hao,Xingce Fan,Mingze Li,Lei Yao,Guoqun Li,Xing Zhao,Hao Huang,Teng Qiu
The implementation of plasmonic materials in heterogeneous catalysis was limited due to the lack of experimental access in managing the plasmonic hot carriers. Herein, we propose a liquid-state surface-enhanced Raman scattering (SERS) technique to manipulate and visualize heterogeneous photocatalysis with transparent plasmonic chips. The liquid-state measurement conquers the difficulties that arise from the plasmon-induced thermal effects, and thus the plasmon based strategies can be extended to investigate a wider range of catalytic reactions. We demonstrated the selection of reaction products by modulating the plasmonic hot carriers and explored the mechanisms in several typical C–C coupling reactions with 4-bromothiophenol (4-BTP) as reactants. The real-time experimental results suggest brand new mechanisms of the formation of C–C bonds on plasmonic metal nanoparticles (NPs): the residue of 4-BTP, but not thiophenol (TP), is responsible for the C–C coupling. Furthermore, this technique was extended to study the evolution of the Suzuki–Miyaura reaction on nonplasmonic palladium metals by establishing the charge transfer channels between palladium and Au NPs. The cleavage and formation of chemical bonds in each individual reaction step were discerned, and the corresponding working mechanisms were clarified.
研究领域:
催化化学
·
材料科学
·
光化学
✓ 已验证
DOI
高影响因子
Optical Materials Express
·
2022
·Vol. 12
·期 7
·2835-2843
·
IF 3.074
Zhinan Yu,Zhengkun Wang,Jie Zhang
A cavity coupled optical fiber decorated by Ag nanoparticles (AgNPs) as the surface-enhanced Raman scattering (SERS) substrate is discussed, and the localized surface plasmon resonance (LSPR) of AgNPs and a cavity enhancement of a silver capillary simultaneously contribute to Raman enhancement. AgNPs were coated on the tapered fiber surface using multiple cycle light induced deposition technology. During the process, two key parameters including the evaporation time and the deposition recycling times were optimized to find an effective coverage of AgNPs. In addition, the forming mechanism based on different distributions of the temperature field and velocity field was discussed. The effect of the cavity length was analyzed. Experiments with R6G (rhodamine 6G) as analyte show that the limit of detection can be down to 10−11 mol/L, with a total enhancement factor (EF) of ∼109, while an additional cavity coupled EF could be ∼7.
研究领域:
光学
·
纳米技术
·
分析化学
✓ 已验证
DOI
高影响因子
JOURNAL OF HAZARDOUS MATERIALS
·
2020
·
IF 9.038
Hao Liu,Yue Guo,Yunxin Wang,Huidan Zhang,Xiaowei Ma,Sisi Wen,Jing Jin,Wei Song,Bing Zhao,Yukihiro Ozaki
Total removal of organic mercury in industrial wastewater is a crucially important task facing environmental pollution in the current world. Herein, we demonstrate the fabrication of Au-NiFe layered double hydroxide (LDH)/rGO nanocomposite as not only an efficient nanozyme with oxidase-like activity but also an efficient surface-enhanced Raman spectroscopy (SERS) substrate to determine organic mercury, with the minimum detection concentration as low as 1 × 10 −8 M. According to the binding energy of X-Ray photoelectron spectrometer (XPS) and the free radicals of electron paramagnetic resonance (EPR) spectra, the mechanism of catalytic enhanced degradation is the production of Au-amalgam on Au surface, accelerating the electron transfer and the generation of O 2 •– radicals from oxygen molecules and •CH 3 radicals from the methyl group in MeHg to participate the oxidase-like reaction. Furthermore, the Au-NiFe LDH/rGO nanocomposite is able to degrade and remove 99.9% of organic mercury in two hours without the secondary pollution by Hg 2+ . In addition, the material can be used for the multiple degradation-regeneration cycles in actual applications, which is significant in terms of the environmental and economic point of view. This work may open a new horizon for both highly sensitive detection and thorough degradation of organic mercury in environmental science and technology .
研究领域:
环境科学与技术
·
纳米生物学
·
分析化学
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）