COLLOIDS AND SURFACES B-BIOINTERFACES
·
2026
·
IF 5.9
Nanke Ma,Anqi Wei,Huiling Peng,Lixia Xie,Yuan Jin,Guangli Li
Cu-MOF-derived Cu/Cu 2 O-embedded carbon integrated with MWCNTs-COOH. • Synergistic hetero-interface with Cu⁺ Lewis acid sites and conductive network. • Sensitive L -DOPA detection with 0.007 μM LOD and broad linear range. • Effective anti-interference against uric acid in biological matrices. • Validated applicability in human serum and urine samples (94.8–105.2%). Reliable monitoring of levodopa ( L -DOPA) is clinically crucial for optimizing Parkinson’s disease therapy and minimizing side effects. Herein, a sensitive electrochemical sensor was constructed using a composite of Cu-MOF-derived Cu/Cu 2 O-embedded carbon integrated with carboxylated multi-walled carbon nanotubes (C-Cu-MOF/MWCNTs-COOH). The key innovation of this work lies in designing a synergistic hetero-interface where carbonization yields Cu and Cu 2 O species within a carbon framework, while the incorporated MWCNTs-COOH establish a conductive network that facilitates electron transfer. The enhanced electrochemical response arises from the synergistic interaction between the mixed-valence copper species and the carbon framework. Specifically, Cu + serves as Lewis acid sites for L -DOPA enrichment while the carbon scaffold together with Cu 0 promotes interfacial electron transfer. Kinetic analysis reveals an adsorption-controlled process involving two-electron and two-proton transfer. Under optimized conditions, the sensor delivers a broad linear response (0.01–15 μM) with a low detection limit of 0.007 μM, alongside satisfactory repeatability, reproducibility, and long-term stability (94.3% retention after 21 days). Notably, uric acid (UA), a major coexisting interferent in physiological fluids with overlapping oxidation potential, is well resolved from L -DOPA at the modified electrode, causing negligible interference in coexistent measurements. Practical applicability is further validated by recoveries of 94.8–105.2% in human serum and urine samples. These results demonstrate that C-Cu-MOF/MWCNTs-COOH is a highly effective sensing platform for L -DOPA, combining excellent sensitivity, selectivity, and practical utility for clinical monitoring.
✓ 已验证
DOI
高影响因子
Journal of CO2 Utilization
·
2023
·
IF 7.7
Yanyan Gong,Yuankun Wang,Peng Li,Ye Yuan,Fangong Kong
Carbamates and related derivatives are crucial skeletons for pesticide design and pharmaceutical chemistry. Recently, a synthetic route for the production of carbamates has drawn great attention, which assembles the economical, renewable and non-toxic CO 2 with propargyl alcohols and amines. This route is 100% atom-economical and free of traditional carbon sources (CO, phosgene, etc .), thus attracting scientists to develop numerous catalytic methods for its effective applications. However, the carbamates produced in these methods generally contained residual catalysts, solvents or byproducts. Consequently, column chromatography purification is inevitably required for all the reports up to now. This limitation has fundamentally hindered the practical application of this route. Herein, a chromatography-free method was proposed for the first time. With the catalysis of a green and economical Cu 2 O/biobased ionic liquid system, the carbamates could be obtained in good to excellent yields and purity. Additionally, the catalytic metal loading reached the lowest level reported by far under 1 bar of CO 2 . Furthermore, this catalytic system could be recycled and reused for at least 5 times.
✓ 已验证
产品关联
DOI
高影响因子
Journal of Materials Chemistry C
·
2023
·Vol. 11
·期 38
·12999-13009
·
IF 6.4
Jinjuan Li,Jing Hu,Nan Li,Miao Cheng,Tao Wei,Qianqian Liu,Ruirui Wang,Wanfei Li,Yun Ling,Yafei Zhang,Bo Liu
Conventional metal oxide semiconductor gas sensors often suffer from high operating temperatures, low selectivity, and complex synthesis processes for NO2 detection. In this work, reduced graphene oxide (rGO) nanosheets are coated on NaOH-etched Cu2O/CuO urchin-like spheres to form Cu2O/CuO@rGO composites via a one-step green synthesis method at room temperature (RT). The gas sensor based on this material has been utilized for detecting NO2 at RT (25 °C), and the effects of Cu2O addition and reaction time on the morphology as well as gas-sensing properties of the as-prepared sensor are investigated. Of interest, the sensor based on the 550Cu2O/CuO@rGO-5 composite has an ultra-high response (S = 871) to 5 ppm NO2 gas at RT with a response/recovery time of 32/73 s, and the detection limit is as low as 90.6 ppt. In addition, the gas sensor shows excellent selectivity and repeatability. The excellent sensing performance of the as-prepared 550Cu2O/CuO@rGO sensor is attributed to the framework structure of Cu2O/CuO@rGO, the urchin-like hierarchical structure of the Cu2O/CuO and the synergistic effect of the p–p (Cu2O–CuO) heterojunction. This exploration of the present work offers a good reference for mass, green, and low-power sensing material preparation.
✓ 已验证
产品关联
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2023
·
IF 15.1
Rui Zhang,Feifei Chen,Haokun Jin,Yong Zhang,Xiaoya Hao,Yingda Liu,Tianming Feng,Xinghua Zhang,Zunming Lu,Weihua Wang,Feng Lu,Hong Dong,Hui Liu,Hui Liu,Yahui Cheng
In Cu-based electrocatalysts, appropriate amount of Cu 0 and high concentration of Cu + are essential for the efficient conversion of CO 2 into C 2+ products. An obstacle of CO 2 electroreduction is the inevitable reduction of Cu + to Cu 0 at cathodic potential. Intermediates confinement is a promising solution to delay Cu + deterioration, in which it is crucial to maintain an appropriate amount of Cu 0 and Cu + species to produce sufficient intermediates to protect most Cu + species. Herein, based on the influence of Cu + /Cu 0 ratio on the reaction process and its feedback, a series of hollow Cu 2 O nanoreactors with different cavity sizes were synthesized to modulate the concentration of intermediates and the coverage degree of Cu + , so as to realize a constant high Cu + /Cu 0 ratio. The optimized hollow Cu 2 O nanoreactors achieved a C 2+ Faradaic efficiency of 70.1 ± 0.2 % at a partial current density of −9.3 ± 0.1 mA cm −2 over 30 h and a large C 2+ -to-C 1 ratio of 9.73. Operando Raman spectra and quasi in - situ Auger electron spectra confirmed that the moderate cavity Cu 2 O nanoreactors led to a full coverage of Cu + and an optimal Cu + /Cu 0 ratio of 8.12:1, which brought the stability of Cu + species and cavity structure, as well as the enhanced C C dimerization.
✓ 已验证
产品关联
DOI
高影响因子
Surfaces and Interfaces
·
2023
·
IF 6.2
Jie Jiang,Yuqiang Ding
As a widely used semiconductor photocatalyst , TiO 2 has been explored in organic compounds hydrogenation. In this study, the hydrogenation of C=N bonds on the surface of TiO 2 was accomplished for the first time utilizing Cu 2 O/TiO 2 type-II (p-n) heterojunction . The probe reactions, hydrogenation of N -benzylphenylamine with benzyl alcohol, and N -methylation of amines with methanol exhibited that the hydrogenation of C=N bonds on TiO 2 surface can be achieved through borrowing hydrogen reaction (BH, alcohols as hydrogen source). Additionally, the BH reaction rate could be improved by adding external H + to the reaction system. The catalytic activity of Cu 2 O/TiO 2 was discovered to remain at an efficient level even after six reaction cycles.
✓ 已验证
产品关联
DOI
高影响因子
NANOTECHNOLOGY
·
2019
·Vol. 30
·期 48
·485706
·
IF 3.399
Feng Long,Wei Li,Wanling Chen,Danni Liu,Yue Chen,Rui Zhou,Penghui Li
In this work, a novel label-free electrochemical biosensor is developed for the detection of galectin-1 (Gal-1) based on gold nanoparticle (AuNP) loaded octahedral Cu2O (Cu2O@Au) nanocomposites. The AuNPs on the surface of the Cu2O nanocrystals not only enhance the electrochemical performance, but also serve as the binding sites for the lactose ligand which can specifically bind with Gal-1. The Cu2O@Au nanocomposites provide the synergic effect of electrochemical signal amplification and lactose–galectin reaction as the recognition strategy. Under optimal conditions, the proposed biosensor exhibits a variation of electrochemical responses to different concentrations of Gal-1 ranging from 0.1 pg ml−1 to 10 ng ml−1. This work presents an alternative electrochemical biosensor for the detection of tumor biomarkers based on a simple and economical lactose ligand incorporated Cu2O@Au biosensor platform.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY
·
2017
·
IF 4.421
Qiuling Ma,Huixuan Zhang,Yuqi Cui,Xiaoyong Deng,Ruonan Guo,Xiuwen Cheng,Mingzheng Xie,Qingfeng Cheng
Cu 2 O decorated TiO 2 nano-tube arrays (Cu 2 O/TiO 2 NTAs) photoelectrode was fabricated through electrodeposition strategy. Meanwhile, physicochemical properties of the resulting photoelectrode were systematically studied by series of measurements. Results indicated that Cu 2 O/TiO 2 NTAs photoelectrode performed a significantly enhanced light absorbance in the visible region between 400 and 800 nm, transient photocurrent density of 0.162 mA Cm −2 , photogenerated charge separation efficiency and 99.9% of photoelectrocatalytic efficiency for decomposition of 2,4,6-trichlorophenol within 120 min Xenon illumination with the help of +1.0 V (vs. SCE) potential. Furthermore, the enhanced visible light responsible photoelectrocatalytic mechanism was proposed and discussed.
✓ 已验证
产品关联
DOI
高影响因子
RSC Advances
·
2017
·Vol. 7
·期 86
·54861-54865
·
IF 3.108
Kun Liu,Houkun Long,Guangyi Wang,Yongbin Sun,Chao Hou,Jian Dong,Xiaoqun Cao
The catalyst Cu3Pt1–Cu2O/SiC was facilely prepared via the in situ reaction of the corresponding compounds supported on SiC in the reaction stream. Cu3Pt1–Cu2O/SiC exhibits excellent catalytic activity for the oxidation of alcohols (conversion of benzyl alcohol and selectivity of benzyl aldehyde are 93% and 98% respectively). The reduction of active Cu2O to inactive Cu0 is the cause behind the deactivation of Cu/SiC. For Cu3Pt1–Cu2O-7/SiC, a Cu2O–Cu3Pt1 alloy formed under the reaction conditions plays an important role in the reaction. Active 5 nm Cu2O nanoparticles are stabilized by the inactive Cu3Pt1 alloy, which was confirmed by control experiments, characterization results and a three-step experiment.
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF MOLECULAR LIQUIDS
·
2024
·
IF 5.3
Huan Cheng,Kuang Luo,Xiaojun Wen,Lijun You,Ning Cai,Jumei Li
In this work, we proposed a straightforward self-assembly and in-situ deposition protocol to construct Cu 2 O/g-C 3 N 4 /Ag composites, which demonstrated peroxidase-like attribute and exceptional SERS activity. These composites proved to be an effective SERS analysis tool for detecting organic fungicides like malachite green (MG) and crystal violet (CV). Remarkably, they achieved detection limits as low as 10 −9 M in DI water as well as fish pond water, and exhibited a strong linear correlation between logarithmic concentrations and SERS intensities (R 2 ≥ 0.97). Beyond that, with the aid of hydrogen peroxide (H 2 O 2 ), the peroxidase-like Cu 2 O/g-C 3 N 4 /Ag composites rapidly degraded MG and CV molecules within just 5 min. Furthermore, their practical reusability based on the peroxidase-like reaction was proved by high SERS performance across 5 detection cycles. These results emphasize the immense potential of Cu 2 O/g-C 3 N 4 /Ag in SERS-based trace fungicide detection and suggest future applications in ecological restoration through peroxidase-like reactions.
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2024
·
IF 9.4
Xiong Yan,Shuo Wang,Ziliang Chen,Yunjie Zhou,Hui Huang,Jie Wu,Tiwei He,Hongyuan Yang,Likai Yan,Kaili Bao,Prashanth W. Menezes,Zhenhui Kang
Developing an efficient electrocatalyst that enables the efficient electrochemical conversion from CO 2 to CH 4 across a wide potential range remains a formidable challenge. Herein, we introduce a precatalyst strategy that realizes the in situ electrochemical reconstruction of ultrafine Cu 2 O nanodomains, intricately coupled on the CeO 2 surface (Cu 2 O/CeO 2 ), originating from the heterointerface comprised of ultrafine CuO nanodomains on the CeO 2 surface (CuO/CeO 2 ). When served as the electrocatalyst for the electrochemical CO 2 reduction reaction, Cu 2 O/CeO 2 delivers a selectivity higher than 49 % towards CH 4 over a broad potential range from −1.2 V to −1.7 V vs . RHE, maintaining negligible activity decay for 20 h. Notably, the highest selectivity for CH 4 reaches an impressive 70 % at −1.5 V vs . RHE. Through the combination of comprehensive analysis including synchrotron X-ray absorption spectroscopy, spherical aberration-corrected high-angle annular dark field scanning transmission electron microscope as well as the density functional theoretical calculation, the efficient production of CH 4 is attributed to the coherent interface between Cu 2 O and CeO 2 , which could converted from the original CuO and CeO 2 interface, ensuring abundant active sites and enhanced intrinsic activity and selectivity towards CH 4 .
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2016
·
IF 5.31
Xiaoli Li,Yun Zhang,Lingyun Jing,Xinghua He
A newly designed N-doped CNTs stabilized Cu 2 O nanoparticles (PVP@CNTs-Cu 2 O) were fabricated and used to remove organic pollutants such as Malachite Green (MG) dye and tetrabromobisphenol A (TBBPA). The introduction of PVP here not only could stabilize Cu 2 O nanoparticles, but also act as active sites for adsorption of organic pollutants. The hybrid mesoporous adsorbent exhibited excellent adsorption performances for MG and TBBPA, which were mainly because of the synergistic effects of inorganic species and polymer. The maximum adsorption capacities of MG and TBBPA by PVP@CNTs-Cu 2 O were 1495.46 and 116.72 mg/g, respectively, significantly higher than pristine CNTs (417.58 and 68.03 mg/g, respectively). The adsorption of MG was independent of ionic strength. In contrast, the increase in ionic strength significantly inhibited the adsorption of TBBPA. Freundlich isotherm model fitted well with the experimental data of both MG and TBBPA adsorption, indicating the heterogeneous surface of PVP@CNTs-Cu 2 O. PVP@CNTs-Cu 2 O demonstrated rapid adsorption rates for both MG and TBBPA, and their adsorption kinetics were analyzed by the pseudo-first-order, pseudo-second-order and Elovich kinetic models. The possible mechanisms of MG and TBBPA adsorption was further explored by means of FTIR and XPS. High adsorption capacity, rapid kinetics, good reusability as well as simple preparation were important advantages for the practical application in MG and TBBPA removal by PVP@CNTs-Cu 2 O.
✓ 已验证
产品关联
DOI
高影响因子
APPLIED CATALYSIS A-GENERAL
·
2013
·
IF 3.41
Wei Zhai,Fengqiang Sun,Wei Chen,Zizhao Pan,Lihe Zhang,Shaohua Li,Shuilan Feng,Yiyi Liao,Weishan Li
Octahedral Cu 2 O particles were prepared on an indium-tin oxide glass via electrodeposition and were employed in the catalytic degradation of p -nitrophenol in the presence of H 2 O 2 . Under irradiation of a warm visible-light source, tungsten halogen lamp, Cu 2 O particles not only acted as a photocatalyst, but might also act as a thermal-catalyst to induce the decomposition of H 2 O 2 and produce O 2 at higher temperatures. The photogenerated electrons and holes could react with H 2 O 2 , O 2 , and H 2 O to produce abundant OH radicals, resulting in the effective oxidation of p -nitrophenol. High-performance liquid chromatography measurements of degradation intermediates showed that p -nitrophenol was first decomposed into hydroquinone and benzoquinone and then mineralized. The degradation efficiency was dependent on electrodeposition time, light intensity, H 2 O 2 amount, and solution temperature. This catalyst could be easily recycled and used in the efficient degradation of other phenolic compounds.
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）