Journal of Biomedical Nanotechnology
·
2022
·Vol. 18
·期 8
·1897-1912
·
IF 3.641
Xu Yingtian,Zhang Zhaokun,Zhang Ying,Yang Dicheng,Liang Yuan,Xu Yan
Endocrine therapy is often used for advanced prostate cancer. However, with cancer progress, prostate cancer gradually resistant to hormone which lead to serious threatens to life of patients. Herein, a multifunctional synergistic core–shell nanoplatform is reported for improving
the therapeutic effect of chemotherapy for advanced or metastatic prostate cancer, and reducing the risk of leakage of chemotherapy drugs. Particularly, Zeolitic imidazolate framework-8 (ZIF-8) is chosen as inner core to load doxorubicin, and the of liposomes which are embedded with IR780
iodide are used as outer shell, and further modified with target ligand that binds to luteinizing hormone releasing hormone receptor. The prepared nanocarrier exhibit satisfactory photothermal effect under near infrared laser irradiation, and the temperature increases to 60.8 °C within
6 min. Meanwhile, the elevated temperature accelerates the degradation of lipid shell, releasing ZIF-8 core to acidic microenvironment of tumor, and resulting in the release of doxorubicin. Moreover, in vivo and in vitro studies have shown the ZIF-D@ALIP core–shell nanoparticles
can achieve targeted drug delivery, pH and NIR dual stimuli-responsive drug release, as well as chemotherapy and photothermal therapy synergistically on the tumor site. In addition, the problem of premature leakage and changes in the physicochemical properties of anticancer drugs are avoided
under the protection of the outer shell structure. Therefore, the core–shell nanostructure proposes a new lipid membrane coating strategy to promote the effective targeting of prostate cancer cells or tissues and provides some insights in clinical treatment for advanced prostate cancer.
研究领域:
肿瘤学
·
药剂学
·
生物医学工程
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DOI
高影响因子
NEW JOURNAL OF CHEMISTRY
·
2016
·Vol. 40
·期 6
·5170-5176
·
IF 3.277
Bibimaryam Mousavi,Somboon Chaemchuen,Behrooz Moosavi,Zhixiong Luo,Nadia Gholampour,Francis Verpoort
Zeolitic imidazole framework (ZIF)-67 is an efficient heterogeneous catalyst for the cycloaddition of carbon dioxide to epoxides to afford cyclic carbonates. In this work, ZIF-67 was synthesized by a simple and straightforward method at room temperature. The coupling reaction in the presence of ZIF-67 without any co-catalyst or solvent was studied under different conditions. The reaction conversion was more than 99% and the selectivity toward chloropropene carbonate was considerably higher (>99%) than the previously reported ZIF-8. Moreover, the ZIF-67 catalyst could be recycled at least four times without noticeable loss of catalytic activity.
研究领域:
化学
·
材料科学
·
环境科学
✓ 已验证
DOI
高影响因子
PLASMA CHEMISTRY AND PLASMA PROCESSING
·
2023
·Vol. 43
·期 6
·2079-2091
·
IF 3.6
Li Yingwen,Gao Fei,Li Yang,Shen Chenyang,Liu Chang-jun
There exist always some H 2 S in natural gas. The industrialized process for H 2 S removal is an energy intense process and must be applied in a large scale. An alternative process is needed. Herein, we report a removal of H 2 S from a model natural gas mixture with methane, ethane and propane by dielectric barrier discharge (DBD), with which the dielectric (quartz) is frosted and coated with a layer of zeolite imidazole framework-67 (ZIF-67) nanoparticles. Compared to the DBD without coating, the average electric field as well as the mean electron energy of the DBD with ZIF-67 coating are higher at the same specific energy input (SEI), leading to a high H 2 S conversion of 75.4% with the limited conversion of methane (less than 2%). No conversions of other low alkanes can be detected. This provides a potential way for the H 2 S removal from the natural gas sources in the remote or isolated region. Graphical abstract
研究领域:
化学工程
·
环境科学
✓ 已验证
DOI
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2025
·
IF 5.4
Qianyu Wang,Changchang Ma,Dandan Liu,Shushan Song,Ziheng Song,Weijie Zhang,Huarui Han,Jiasheng Zhu,Kai Wei,Sheng Feng
Confining nano zero-valent iron (nZVI) into porous materials could prevent its aggregation and passivation. In this study, we confined nZVI into the cavity of zeolitic imidazolate framework-8 (ZIF-8) via sequential pre-adsorption ferric ion (Fe(III)) and NaBH 4 reduction processes. The optimized Cr(VI) removal rate of ZIF-8 confined nZVI (nZVI@ZIF-8) reached 1.2 × 10 −1 min −1 , 9.2- and 37.5-fold that of nZVI and ZIF-8, respectively. Interestingly, the removal rate constants of nZVI@ZIF-8 toward Cr(VI) still reached 9.6 × 10 −2 min −1 and 6.7 × 10 −2 min −1 with initial pH of 7.0 and 9.0, respectively, 13.0 (7.4 ×10 −4 min −1 ) and 23.9 times that of nZVI. More importantly, channels confinement significantly improved the reactive lifetime of nZVI for Cr(VI) removal. The electro-donating -NH 2 provided positive charge sites for CrO 4 2- or HCrO 4 - adsorption. Subsequently, the difference of Fermi level between nZVI and ZIF-8 drove electrons transfer from nZVI to ZIF-8 for surface Cr(VI) reduction. This study provides an avenue to enhance the performance of nZVI toward heavy metal ions removal by coupling surface adsorption and nano confinement.
研究领域:
环境科学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
INORGANIC CHEMISTRY COMMUNICATIONS
·
2025
·
IF 5.4
Qifan Yang,Haodong Xie,Xiang Ni,Li Liu,Yuan Xue,Yan Liu,Lei Wang,Hongjun Zhu
Adsorptive separation of C 2 H 2 from C 2 H 4 , which could deal with multi-steps for their similar kinetic diameter and physical properties, still poses a significant challenge. In this work, we prepared two metal cations (Co 2+ , Zn 2+ )-exchanged aluminosilicate FAU zeolites as an inorganic porous matrix, and grafted an organic zeolitic imidazole framework crystal layer to construct the inorganic–organic composites for gas separation process of C 2 H 4 among the mixed gas components. Such inorganic–organic porous composites can adsorb C 2 H 2 and hinder the large-sized C 2 H 4 . The Co-FAU@ZIF-8 composite was verified through breakthrough experiments and demonstrated a promising adsorptive volume of 1.46 mmol g −1 with an IAST selectivity of C 2 H 2 /C 2 H 4 of 5.6 at 298 K, respectively. Via powder X-ray diffraction crystallography and combined spectroscopy, we found that the exchanged metallic cation located at the accessible s 6 r , and served as the anchor point for the epitaxy of different crystals. Such tunable features ( i.e. , metallic centers and pore diameter) provide a potential pathway for the sub-sequential development of highly efficient adsorptive materials.
研究领域:
材料科学
·
化学工程
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF HAZARDOUS MATERIALS
·
2025
·
IF 11.3
Haoran Zheng,Jiayu Guo,Han Wang,Yurou Wang,Wenxiang Zhou,Ke Liu,Qiang Ma,Yanfei Qi
Bacteria are prevalent environmental pollutants. Live bacteria can proliferate and spread under appropriate conditions, presenting higher risks compared to non-viable counterparts. However, detecting live bacteria remains a challenge. Adenosine triphosphate (ATP), an energy currency in organisms, offers a reliable biomarker for the live bacteria sensing. Herein, we developed a zeolitic imidazolate framework-90 (ZIF-90) enhanced ATP sensing platform to detect live bacteria. The nanosystem which based on ZIF-90, encapsulating the DNA decorated magnetic beads (MB@S1) through self-assembly. When the S. aureus aptamers on ZIF-90 bonded to bacteria, the skeleton structure of ZIF-90 was disrupted by ATP leakage from live bacteria, leading to the release of MB@S1. Then, the MB@S1 initiated the hybridization chain reaction (HCR) and they were transduced by CRISPR-Cas12a to amplify the signal twice. The proposed ZIF-90 blocking sensing strategy (ZIF-90 strategy) exhibited remarkable sensitivity with the limit of detection (LOD) down to 0.223 pM for ATP detection, about 500 folds lower than the traditional ATP aptamer blocking sensing strategy (aptamer strategy). Furthermore, we used a smartphone for on-site analysis, realizing the quantification of live S. aureus with the LOD of 2.0 CFU/mL. Therefore, the approach possessed great application potential for public health, environment monitoring, bioanalysis and food safety.
研究领域:
生物化学
·
分子生物学
·
纳米医学
·
环境科学
·
食品安全
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF HAZARDOUS MATERIALS
·
2019
·
IF 7.65
Hanxiao Duan,Xiang Hu,Zhirong Sun
Zeolitic imidazolate framework-8 (ZIF-8) was synthesized by solvothermal method and the adsorption pore size was adjusted by changing the amount of template agent. The ZIF-8@SiO 2 @Fe 3 O 4 derived from self-assembly of ZIF-8 and SiO 2 @Fe 3 O 4 were then synthesized and used for ceftazidime (CAZ) removal. ZIF-8 was a regular dodecahedral particle with uniform particle size. The pore diameter was 6.47 nm and the specific surface area was 1182.5 m²·g −1 in ZIF-8@SiO 2 @Fe 3 O 4 . The adsorption of CAZ on ZIF-8@SiO 2 @Fe 3 O 4 as a function of adsorption temperature, contact time, ionic strength solution pH, and humic acid concentration were investigated. The error of equilibrium adsorption capacity between model fitting and actual experiments is only 1.19%. Kinetics for CAZ removal on ZIF-8@SiO 2 @Fe 3 O 4 was found to follow pseudo-second-order kinetics. Langmuir, Freundlich and Sips isotherm fitted the adsorption data well and gave similar correlation coefficients, suggesting a single layer adsorption of CAZ on ZIF-8@SiO 2 @Fe 3 O 4 . The ZIF-8@SiO 2 @Fe 3 O 4 showed no apparent loss in CAZ adsorption after five cycles. These features indicate that the ZIF-8@SiO 2 @Fe 3 O 4 may be a promising adsorbent for CAZ removal from aqueous solution.
研究领域:
环境科学
·
材料科学
✓ 已验证
DOI
高影响因子
ENERGY & FUELS
·
2022
·
IF 4.654
Yuman Zhang,Xiaolin Zhu,Suya Sun,Qirui Guo,Meigui Xu,Guan Wu
The advanced design of heterostructured fibers with ordered transport channels and porous frameworks for high-speed ions/electrons kinetics is principally fundamental for high-performance fiber-based supercapacitors (FSCs). However, typically low energy-storage performances restrict their substantive applications due to a fibrous restacking phenomenon and poor interfacial charge transfer. Here, we develop an ordered core–shell fiber, wherein the porous zeolitic imidazolate framework-67 (ZIF-67) polyhedron shell is uniformly loaded on a highly conductive Ti3C2Tx core via a versatile microfluidic method. Due to the improved porous generation, ordered porous pathways, large exposed surface, and in situ interfacial electron transfer, the ZIF-67@Ti3C2Tx fiber displays excellent volumetric capacitance (972 F cm–3) and long-term cycling stability (90.8% capacitive retention after 20 000 cycles) in 1 M KOH electrolytes. Meanwhile, the flexible solid-state ZIF-67@Ti3C2Tx FSCs maintain a good capacitance, large bending/wearable stabilities, and steady temperature-dependent capability. Based on those significant electrochemical performances, the supercapacitors can impressively power various electrical devices [e.g., light-emitting diodes (LEDs), displays, electric fans, pinwheels, and rolling bells], which will guide the practical progress of miniaturized energy technologies and smart electronics.
研究领域:
材料科学
·
能源存储技术
·
纳米技术
✓ 已验证
DOI
高影响因子
DYES AND PIGMENTS
·
2022
·
IF 5.122
Qing Sun,Jingfeng Zhao,Zhibo Hu,Jian Zhang,Jun Yan,Jiawei Sheng
In this work, we successfully report the design and synthesis of rod-like CoAl 2 O 4 /halloysite hybrid pigment from zeolitic imidazolate framework-67 (ZIF-67, a Co-based MOF) and tubular halloysite via a facile two-step route for the first time. The as-prepared nanostructures were thoroughly characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM), Fourier transform infrared reflection (FTIR Spectroscopy), thermogravimetric and differential scanning calorimetry (TG-DSC), X-ray photoelectron spectrometer (XPS), ultraviolet–visible spectrometry (UV–vis) and CIE L* a* b* colorimetric method . XRD patterns indicated that the presence of CoAl 2 O 4 spinel was observed at various temperatures ranging from 800 to 1100 °C. The SEM and TEM images showed that the nano-pigment has a rod-like hybrid structure composed of nano CoAl 2 O 4 particles and SiO 2 . The color performance of the fabricated pigments was evaluated and given suitable color coordinates (L* = 44.72, a* = −14.40, b* = −37.83) and (L* = 42.57, a* = −7.68, b* = −41.14) at the calcination temperature of 1100 °C for 2 h and 3 h, respectively. The mechanism study indicated that these composites were formed by Co 3 O 4 derived of ZIF-67 as highly active cobalt source and Al 2 O 3 decomposed from halloysite substrate as aluminum source. In addition, the corrosion resistance test showed that the CoAl 2 O 4 composites retain crystalline stability, almost no color deviation in CIE chromatic system even after 1 M HCl leaching. Furthermore, the CoAl 2 O 4 /halloysite exhibited excellent thermal and suspension stability, which indicated it could be a promising candidate for ceramic glazes and water-borne coatings. These findings provide insight into a new strategy for the synthesis of clay mineral-based ceramic pigment .
研究领域:
材料科学
·
无机化学
✓ 已验证
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2021
·
IF 13.273
Rui Ding,Yan Dai,Wenji Zheng,Xiangcun Li,Xiaoming Yan,Yi Liu,Xuehua Ruan,Shaojie Li,Xiaochen Yang,Kai Yang,Gaohong He
The trade-off between gas permeability and selectivity represents a huge challenge for membrane separation. In this work, we design unique polystyrene-acrylate (PSA) modified hollow ZIF-8 (PHZ) nanospheres via a facile hard template-incomplete etching strategy as fillers for mixed matrix membranes (MMMs). In the vesicles shaped PHZ, the hollow core builds a low-resistance CO 2 transport freeway, leading to improved CO 2 permeability. Meanwhile, the outside PSA layer intensifies the interface affinity between ZIF-8 and Pebax through molecular chains entanglements and hydrogen bonding, enhancing membrane selectivity. Through controlling the PSA etching process, both the hollow core with tunable size and the outside PSA layer with adjustable thickness are achieved. The 10 wt% PHZ-2/Pebax MMMs present the best performance with a CO 2 permeability of 172.4 Barrer and CO 2 /N 2 selectivity of 87.9. The higher CO 2 /N 2 selectivity proves that the PSA layer on the PHZ has better compatibility with Pebax. The higher CO 2 permeability is attributed to the low-resistance hollow core. The gas separation performance of PHZ-based MMMs not only well exceeded the 2008 Robeson upper-bond line but also was superior to those of other published MOF-based MMMs. The concept of vesicle-shaped PHZ paves a way to concurrently enhance both the gas permeability and selectivity of MMMs.
研究领域:
材料科学
·
化学工程
✓ 已验证
DOI
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2019
·
IF 4.175
Yanfei Li,Yuanyuan Fu,Wenbin Liu,Yonghai Song,Li Wang
A novel hollow Co-Co 3 O 4 coated with carbon nanotubes (CNTs) nanostructure was designed. Here, zeolite imidazolate framework-67 cubes were used as sacrificial template and carbonized under H 2 /Ar atmosphere along with in-situ growth of CNTs to form Co nanostructures@CNTs. Then the Co nanostructures@CNTs was treated by thermal-oxidation under air to further construct hollow Co-Co 3 O 4 @CNTs. The obtained hollow Co-Co 3 O 4 @CNTs was characterized by scanning electron microscopy, transmission electron microscopy , N 2 adsorption/desorption isotherms, X-ray powder diffraction, X-ray photoelectron spectroscopy and electrochemical techniques . It was found that the hollow Co-Co 3 O 4 @CNTs cubes were wrapped by lots of CNTs. As it was used as anode materials for lithium ion batteries (LIBs), after cycling 200 cycles at 0.2 A g −1 , the reversible capacity was still kept at 806.7 mA h g −1 . Excellent cycle stability and Li + storage capacity originated from the hollow nanostructures and the encapsulation of CNTs around hollow Co-Co 3 O 4 cubes to buffer the volume change of Co 3 O 4 and improve the electrical conductivity . Meanwhile, the increased specific surface area could effectively improve the storage of Li + . Therefore, the hollow Co-Co 3 O 4 @CNTs might have potential application in LIBs.
研究领域:
材料科学
·
电化学
✓ 已验证
DOI
高影响因子
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
·
2022
·Vol. 23
·期 10
·5629
·
IF 6.208
Yunbo Zhao,Hongshui Wang,Xianrui Zou,Donghui Wang,Ying Fan,Xiaoyan Zhao,Mingjun Li,Lei Yang,Chunyong Liang
Bone substitutes with strong antibacterial properties and bone regeneration effects have an inherent potential in the treatment of severe bone tissue infections, such as osteomyelitis. In this study, vancomycin (Van) was loaded into zeolitic imidazolate framework-8 (ZIF-8) to prepare composite particles, which is abbreviated as[email protected]As a pH-responsive particle, ZIF-8 can be cleaved in the weak acid environment caused by bacterial infection to realize the effective release of drugs. Then,[email protected]was loaded into polyvinyl alcohol (PVA) fiber by electrospinning to prepare PVA/[email protected]composite bone filler. The drug-loading rate of[email protected]was about 6.735%. The membranes exhibited super hydrophilicity, water absorption and pH-controlled Van release behavior. The properties of antiE. coliandS. aureuswere studied under the pH conditions of normal physiological tissues and infected tissues (pH 7.4 and pH 6.5, respectively). It was found that the material had good surface antibacterial adhesion and antibacterial property. The PVA/[email protected]membrane had the more prominent bacteria-killing effect compared with the same amount of single antibacterial agent containing membrane such as ZIF-8 or Van loaded PVA, and the antibacterial rate was up to 99%. The electrospun membrane had good biocompatibility and can promote MC3T3-E1 cell spreading on it.Keywords:ZIF-8;drug loading;electrospinning;antibacterial activity;cell adhesion
研究领域:
材料科学
·
生物医学工程
·
药学
·
组织工程
✓ 已验证
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）