JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
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2022
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IF 5.756
Jinhua Zhu,Danyang Zhou,Dandan Wu,Wei Liu,Xiuhua Liu
In this work, a highly effective separation approach mediated by 5-Lipoxygenase (5-LOX) was established for screening and isolation of anti-inflammatory ingredients from leaves of Lonicera japonica Thunb. (LLJT). Using 5-LOX immobilised on TiO2 nanotubes as a microreactor, the targeted screening was exploited by combining with HPLC-MS system. Four compounds confirmed as luteolin, luteoside, lonicerin, and isochlorogenic acid C and a fraction (M1) were screened out to be potent inhibitors of 5-LOX. Their anti-inflammatory activities were further investigated and confirmed by RAW 264.7 cells inflammation model and rat foot swelling model. Furthermore, M1 was prepared by MCI GEL CHP20P column chromatography, and further separated by Pre-HPLC. One new compound confirmed to be 5,7,3′,4′-tetrahydroxyflavone-7-O-sambubioside was first isolated from LLJT. The results provide a new method for the effective separation of active components derived from natural products.HighlightsA 5-LOX mediated separation method was established for isolation of anti-inflammatory compounds.An anti-inflammatory ingredient was separated by MCI GEL CHP20P column chromatography.One new compound was first isolated from leaves of Lonicera japonica Thunb.5-LOX was immobilised on TiO2 nanotubes and exploited by combining with HPLC-MS system.The anti-inflammatory activity of screened components was evaluated.
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CHEMICAL ENGINEERING JOURNAL
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2022
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IF 16.744
Shilan Zhang,Songsong Zhi,Hongju Wang,Jing Guo,Weihao Sun,Lu Zhang,Yi Jiang,Xiaguang Zhang,Kai Jiang,Dapeng Wu
A solid-state laser scanning treatment (SLST) was adopted to synthesize anatase/rutile TiO 2 heterojunction with effective charge carrier separation and high surface adsorption performances for the photodegradation of sulfamethoxazole (SMX). The 1064 nm pulsed fiber laser could in-situ generate rutile zones on the pristine sheet-like anatase crystal enclosed by (0 0 1) facets, which could form the well-defined anatase/rutile interface to promote the formation of dominating active species ( h + and ∙OH) on the anatase zones. X-ray absorption fine structure (XAFS) measurements, low temperature electron paramagnetic resonance (LT-EPR) as well as the density functional theory (DFT) simulation proved that the oxygen vacancies (V O ) could both introduce defective energy states to promote the light absorption and enhance the SMX adsorption on anatase zones. Based on the delicately designed micro-zones, the photodegradation efficiency of the optimized catalyst could reach 99.3 %, which demonstrated ∼7 times higher performance than that of pristine TiO 2 and exhibited robust stability under environmental conditions. Gaussian and Vienna Ab Initio Package (VASP) programs were used to provide detailed degradation pathways and mechanism for SMX. This SLST could be potentially employed to create function-specified zones on various catalysts for different applicational aims.
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JOURNAL OF HAZARDOUS MATERIALS
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2022
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IF 14.224
Jiabao Wu,Ying Tao,Chi Zhang,Qiong Zhu,Dieqing Zhang,Guisheng Li
Photoelectrochemical (PEC) activation of chloride ions (Cl - ) to degrade persistent organic pollutants (POPs) is a promising strategy for the treatment of industrial saline organic wastewater. However, the wide application of this technology is greatly restricted due to the general photoanode activation of Cl - with poor capability, the propensity to produce toxic by-products chlorates, and the narrow pH range. Herein, oxygen vacancies-enriched titanium dioxide (O v -TiO 2 ) photoanode is explored to strongly activate Cl - to drive the deep mineralization of POPs wastewater in a wide pH range (2−12) with simultaneous production of H 2 . More importantly, nearly no toxic by-product of chlorates was produced during such PEC-Cl system. The degradation efficiency of 4-CP and H 2 generation rate by O v -TiO 2 were 99.9% within 60 min and 198.2 μmol h −1 cm −2 , respectively, which are far superior to that on the TiO 2 (33.1% within 60 min, 27.5 μmol h −1 cm −2 ) working electrode. DFT calculation and capture experiments revealed that O v -TiO 2 with abundant oxygen vacancies is conducive to the activation of Cl - to produce more reactive chlorine species, evidenced by its high production of free chlorine (48.7 mg L −1 vs 7.5 mg L −1 of TiO 2 ). The as-designed PEC-Cl system in this work is expected to realize the purification of industrial saline organic wastewater coupling with green energy H 2 evolution.
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
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2022
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IF 9.965
Yuzhen Jiao,Yajie Chen,Wei Han,Shumei Liang,Wei Li,Guohui Tian
Metal-organic frameworks-based hybrids with desirable components, structures, and properties have been proven to be promising functional materials for photocatalysis and energy conversion applications. Herein, we proposed and prepared ZnSe sensitized hierarchical TiO 2 nanosheets encapsulated MIL-125(Ti) hollow nanodisks with sandwich-like structure (MIL-125(Ti)@TiO 2 \ZnSe HNDs) through a successive solvothermal and selenylation reaction route using the as-prepared MIL-125(Ti) nanodisks as precursor. In the ternary MIL-125(Ti)@TiO 2 \ZnSe HNDs hybrid, TiO 2 nanosheets were transformed from MIL-125(Ti) and in situ grown on both sides of the MIL-125(Ti) shell, forming sandwich-like hollow nanodisks, and the ratio of MIL-125(Ti)/TiO 2 can be tuned by changing the solvothermal time. The ternary hybrids possess the advantages of enhanced incident light utilization and abundant accessible active sites originating from bimodal pore-size distribution and hollow sandwich-like heterostructure, which can effectively promote CO 2 photoreduction reaction. Especially, the formed multi-channel charge transfer routes in the ternary heterojunctions contribute to the charge transfer/separation and extend the lifespan of charge-separated state, thus boosting CO 2 photoreduction performance. The CO (513.1 μmol g −1 h −1 ) and CH 4 (45.1 μmol g −1 h −1 ) evolution rates over the optimized ternary hybrid were greatly enhanced compared with the single-component and binary hybrid photocatalysts.
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ACS Applied Bio Materials
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2022
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IF 0
Jinglin Zhang,Huakai Chen,Tongyao Lin,Fengjuan Yang,Jingxian Zhang,Xiang Cai,Yunhua Yang,Peng Zhang,Shaozao Tan
Titanium (Ti) is an excellent medical metal material, but the absence of good antibacterial property restricts its widespread application. To overcome this, we thus conducted a series of modifications for Ti. First, a titanium dioxide (TiO2) nanorod array was generated on the Ti surface by hydrothermal treatment (TiO2/Ti). With the polymer-mediated self-assembly method, a continuous copper (Cu) shell structure on the surface of the nanorod was then generated to form a TiO2@Cu core–shell nanorod array as coating for Ti (TiO2@Cu/Ti). Using pure Ti as the control group, the antibacterial properties of TiO2/Ti and TiO2@Cu/Ti were appraised. The results manifested that the mechanical and chemical dual function of the released Cu2+ and TiO2 nanorod array could effectively kill bacteria on the surface of Ti. Besides, the obtained coating exhibited no cytotoxicity and favorable biocompatibility. In this work, we found an antibacterial strategy based on multiple sterilization pathways, which made Ti have good antibacterial property and further improved its biocompatibility.
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INTERNATIONAL JOURNAL OF ENERGY RESEARCH
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2022
·Vol. 46
·期 13
·19221-19232
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IF 4.672
Vi Thuy Thi Phan,Toan Minh Pham,Hau Quoc Pham,Tai Thien Huynh,Thi Hong Tham Nguyen,Van Thi Thanh Ho
Summary Highly stable and cost-effective electrocatalysts are of importance in regulating energy conversion efficiency and commercial feasibility of direct methanol fuel cells (DMFCs). So far, integrating transition metals into Pt-based catalysts to enhance their catalytic performances for methanol electro-oxidation reaction (MOR) at the anode of DMFCs has received significant interest. This study witnessed the first time of depositing Pt 3 Co 1 alloy nanoparticles (NPs) on robust Ti 0.9 Ir 0.1 O 2 supports utilizing a modified reduction method that used NaBH 4 as a reducing agent in the absence of surfactants or stabilizers. This novel combination not only reduces the usage of costly and easily-deactivated Pt but also significantly improves catalytic activity and poisoning tolerance for MOR. Regarding electrocatalytic performance, the onset potential and the mass activity of the Pt 3 Co 1 /Ti 0.9 Ir 0.1 O 2 catalyst are ~0.1 V vs NHE and 316.16 mA/mg Pt , respectively, which are 4.5-fold lower and 1.5-fold higher than the corresponding figures for the commercial Pt/C (E-TEK) catalyst, ~0.45 vs NHE and 206.83 mA/mg Pt , indicating superior catalytic activity and CO-tolerance of the former over the latter. Furthermore, the superior anti-poisoning ability and stability of the Pt 3 Co 1 /Ti 0.9 Ir 0.1 O 2 catalyst are demonstrated by its 2.2-fold higher I f /I b ratio in MOR and lower degradation rate in the 60-min chronoamperometry (CA) and 3000-cycle scanning tests than the Pt/C counterpart. These enhancements could be abscribed to synergistic influence between the Pt-Co alloy NPs and the robust Ti 0.9 Ir 0.1 O 2 support. The addition of Co into the catalyst to promote removal of Pt-poisoning species as well as the use of highly corrosion-resistant Ir-doped TiO 2 as a catalyst support play a decisive role in boosting electrochemical behaviors of the Pt 3 Co 1 / Ti 0.9 Ir 0.1 O 2 catalyst. Generally, the success of this work in synthesizing high-performance Pt 3 Co 1 /Ti 0.9 Ir 0.1 O 2 catalyst could serve as groundwork for further development of TiO 2 -based material supported bimetallic catalysts for applications in the electrochemical catalysis field.
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MICROCHEMICAL JOURNAL
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2022
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IF 5.304
Huiqin Chang,Meng Jiang,Qiying Zhu,Anqi Liu,Yuyin Wu,Canguo Li,Xiangyue Ji,Li Gong,Shanshan Li,Zhiwei Chen,Ling Kong,Lei Han
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-COV-2) is a cluster of β coronaviruses. The 2019 coronavirus disease (COVID-19) caused by SARS-COV-2 is emerging as a global pandemic. Thus, early diagnosis of SARS-COV-2 is essential to prevent severe outbreaks of the disease. In this experiment, a novel label-free photoelectrochemical (PEC) immunosensor was obtained based on silver sulfide (Ag 2 S) sensitized titanium dioxide@bismuth tungstate (TiO 2 @Bi 2 WO 6 ) nanocomposite for quantitative detection of SARS-COV-2 nucleocapsid protein. The constructed TiO 2 @Bi 2 WO 6 hollow microspheres had large specific surface area and could produce high photocurrent intensity under visible light illumination. Ag 2 S was in-situ grown on the surface of thioglycolic acid (TGA) modified TiO 2 @Bi 2 WO 6 . In particular, TiO 2 @Bi 2 WO 6 and Ag 2 S formed a good energy level match, which could effectively enhance the photocurrent conversion efficiency and strength the photocurrent response. Ascorbic acid (AA) acted as an effective electron donor to effectively eliminate photogenerated holes. Under optimal experimental conditions, the constructed immunosensor presented a supersensitive response to SARS-COV-2 nucleocapsid protein, with a desirable linear relationship ranged from 0.001 to 50 ng/mL for nucleocapsid protein and a lower detection limit of 0.38 pg/mL. The fabricated sensor exhibited a wide linear range, excellent selectivity, specificity and stability, which provided a valuable referential idea for the detection of SARS-COV-2.
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SEPARATION AND PURIFICATION TECHNOLOGY
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2022
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IF 9.136
Ming Xiao,Ruixue Li,Xinyu Hu,Wenke Zhu,Zhuo Yu,Hongbo Xiao,Wenlei Wang,Ting Yang
This paper is focused on the functional photocatalyst of in-situ carbon-doped TiO 2 decorated Fe 3 O 4 heterojunctions (C/TiO 2 @Fe 3 O 4 ) for the efficient photocatalytic oxidation of As(III). Series of characterizations show that the photocatalytic activity of TiO 2 changes from a single UV wavelength to visible light excitation when carbon atoms are successfully doped in the TiO 2 lattice, expanding the utilization rate of light energy. DFT calculation further confirmed that the C–O–Ti bonds can diminish the theoretical band-gap of TiO 2 . Furthermore, the successful construction of C–O–Ti and Ti–O–Fe interface bonds provide pathways for fast electron transfermation, which can effectively prompt the separation of photo-generated carriers and enhance the photocatalytic oxidation efficiency of As(III). The application results showed that the synthesized C/TiO 2 @Fe 3 O 4 photocatalyst by introducing Fe 3 O 4 with a mass fraction of 1% can complete the transformation of As(III) (10,000 μg/L, 40 mL) to As(Ⅴ) within 12 min under visible light irradiation. In addition, C/TiO 2 @Fe 3 O 4 exhibits excellent reusability, which remains 100% photooxidation efficiency of As(III) without changing crystal structure after 6 cycles and can also be recovered completely with magnet. The remarkable photocatalytic oxidation performances of C/TiO 2 @Fe 3 O 4 can be ascribed to the synergistic effects of OH, O 2 − and h + in the photocatalytic oxidation process and the constructed C–O–Ti and Ti–O–Fe interface bonds.
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Biomedical Materials
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2022
·Vol. 17
·期 4
·045025
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IF 4.103
Mingchao Jin,Juli Zhu,Zhipeng Meng,Xuesheng Jiang,Zhuo Chen,Juntao Xu,Hongliang Gao,Junkun Zhu,Fengfeng Wu
Titanium dioxide (TiO2), as one of the titanium (Ti)-based implants, holds a promise for a variety of anti-bacterial application in medical research. In the current study, a functional molybdenum disulfide (MoS2)/polydopamine (PDA)-LL-37 coating on titanium dioxide (TiO2) implant was prepared. Anodic oxidation and hydrothermal treatment was given to prepare TiO2 nanotubes-MoS2/PDA-LL-37 (T-M/P-L). The in vitro osteogenic effect of T-M/P-L was evaluated by measuring mesenchymal stem cell (MSC) adhesion, proliferation, alkaline phosphatase (ALP) activity, extracellular matrix (ECM) mineralization, collagen secretion and osteoblast-specific messenger RNAs (mRNAs) expression. The determination on the anti-bacterial ability of T-M/P-L was followed. Furthermore, the ability of T-M/P-L to promote bone formation in vivo was evaluated. Near-infrared (NIR) laser irradiation exposure enabled the T-M/P-L coating-endowed Ti substrates to hold effective anti-bacterial ability. T-M/P-L promoted the adhesion and proliferation of MSCs. In addition, an increase was witnessed regarding the ALP activity, collagen secretion and ECM mineralization, along with the expression of runt-related transcription factor 2, ALP and osteocalcin in the presence of T-M/P-L. Additionally, T-M/P-L could stimulate endothelial cells to secrete vascular endothelial growth factor (VEGF) and promote capillary-like tubule formation. Upon NIR laser irradiation exposure, T-M/P-L not only exhibited efficient in vivo anti-bacterial activity but also facilitated new bone formation. Collectively, T-M/P-L had enhanced anti-bacterial and osteogenic activity under NIR laser irradiation.
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COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
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2022
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IF 5.518
Min Zhang,Muhammad Arif,Yunyuan Dong,Xiaobin Chen,Xiaoheng Liu
In photocatalysis as a “green chemistry” technology, the development of efficient strategies to fabricate high-performance micro-nano photocatalysts with robust solar light utilization to deal with persistent pharmaceutical products in the wastewater system is crucially important. In order to improve the photoelectric activity, interfacial charge transfer, and reduce the recombination rate of photo-generated electron-hole pair, a Z-scheme TiO 2−x @ZnIn 2 S 4 heterojunction was prepared by hydrothermal method . The morphological structure and optical properties of the prepared catalysts were extensively characterized. Experimental results show that the rich of oxygen vacancies in TiO 2−x benefits the formation of local defect energy levels at the bottom of the CB , which can be advantageous to broaden the light absorption range. Likewise, the TiO 2−x @ZnIn 2 S 4 showed 12.4-fold and 7.70-fold higher photocatalytic performance pristine TiO 2−x and ZnIn 2 S 4 towards the degradation of tetracycline hydrochloride (TCH) and nitrofurantoin (NFT) in real water matrix and solution water. Furthermore, the photo-decomposition pathway of NFT was proposed by HPLC-MS, and the Z-scheme electron transfer mechanism in TiO 2−x @ZnIn 2 S 4 heterojunction was proposed and discussed in detail. This work emphasizes a facile method for designing high-efficiency oxygen vacancy mediated titanium-based photocatalysts with excellent photoactivity in environmental remediation.
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MATERIALS RESEARCH INNOVATIONS
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2022
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IF 0
Shridevi Salagare,Prashanth Shivappa Adarakatti,Suma B P,Yarradoddappa Venkataramanappa
A nitrite sensing platform has been constructed using a TiO2-reduced graphene oxide (RGO) nanocomposite incorporated into a glassy carbon electrode. Reduced graphene oxide is integrated in a simple technique for the manufacture of titanium dioxide (TiO2). Spectroscopic and electrochemical techniques have all been used to characterise the TiO2- RGO nanocomposite. In 3 mM and pH 6.0 phosphate buffer solutions, the TiO2-reduced graphene oxide nanocomposites tailored glassy carbon electrode demonstrated outstanding electro-catalytic nitrite oxidation activity. The square root of scan rate is also proportional to the oxidation peak current, showing that the nitrite redox reaction involves a diffusion-controlled mechanism. Using linear sweep voltammetry, the sensitivity and detection limit for nitrite at the modified electrode were determined to be 4.853 μA/μM cm2 and 0.006 µM respectively, over a concentration range of 10 - 2000 µM. Further, the nanocomposite is used to measure NO2- in water and buttermilk samples quantitatively.
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LANGMUIR
·
2022
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IF 4.331
Zhiwei He,Hanqing Wu,Zhen Shi,Xianming Gao,Yuping Sun,Xianguo Liu
Oceanic oil spill and the discharge of industrial oily wastewaters can cause significant threats to the ecological environment and human health. Herein, we design a durable TiO2/PDA-based superhydrophobic paper for efficient oil/water separation. Bioinspired from mussel adhesive proteins, the mechanical durability of the as-prepared superhydrophobic paper is enhanced by the deposition of polydopamine (PDA) onto cellulosic fibers via self-polymerization of dopamine. The TiO2/PDA-based superhydrophobic paper shows a high water contact angle of 168.2° and an oil contact angle of ∼0°, exhibiting excellent superhydrophobicity and superoleophilicity. Furthermore, the as-prepared superhydrophobic paper possesses excellent chemical stability, thermal stability, and mechanical durability in terms of being immersed in corrosive solutions and solvents and boiling water and being subjected to the sandpaper abrasion test, respectively. More importantly, the separation efficiency of the TiO2/PDA-based superhydrophobic paper for an oil/water mixture is 97.2%, and it maintains a separation efficiency above 94.3% even after 15 cyclic separation processes. Furthermore, the separation efficiency for water-in-oil emulsions is higher than 93.7% after 15 cyclic separation tests, showing its excellent recyclable stability for water-in-oil emulsions. Therefore, the rationally designed TiO2/PDA-based superhydrophobic paper shows great potential in the practical applications of self-cleaning, antifouling, and oil/water separation.
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