Frontiers in Chemistry
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2019
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IF 3.782
Li Zhanyi,Liu Guoguang,Su Qing,Lv Chunyan,Jin Xiaoyu,Wen Xiaoqing
Naproxen (NPX) is one of the most common pharmaceutical and personal care products found in surface water, which is recalcitrant to degradation by biological treatment or complete removal via traditional sewage treatment processes. In this study, nanoscale γ-FeOOH was synthesized and characterized by X-ray diffraction, scanning electron microscopy, surface analysis, and analysis of the forbidden bandwidth. Under UV irradiation, γ-FeOOH had the capacity to rapidly photodegrade NPX. The photodegradation rate of NPX was dependent on the concentration of γ-FeOOH in solution, initial NPX concentration, and pH. By increasing the concentration of γ-FeOOH, the NPX photodegradation rate was increased and then remained stable. Furthermore, the highest photodegradation rate for NPX was observed under acidic conditions. Through the analysis of the active substances (such as h+, e−, OH, 1O2, and O2·-) by electron spin resonance, the photocatalytic mechanism of NPX degradation on γ-FeOOH was determined to be semiconductor photocatalysis.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2019
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IF 4.784
Rong Yang,Xiaoxue Wang,Shuai Liu,Wenjie Zhang,Penghui Wang,Xin Liu,Yanhan Ren,Xiaoyan Tan,Bo Chi
While peptide-directed scaffolds now serve as well-established platforms for biomimetic three-dimensional (3D) extracellular matrices (ECM), challenges still remain for chondrogenesis through direct mediation of stem cells. Here, biocompatible poly (γ-glutamic acid) (γ-PGA) hydrogels with robust mechanical properties were developed based on methacrylate-γ-PGA (γ-PGA-GMA) and cysteamine functionalized γ-PGA (γ-PGA-SH) for cartilage regeneration. The γ-PGA hydrogels demonstrated good self-crosslinking property as well as tunability through conjugation between active thiol groups of γ-PGA-SH and methacrylate moieties of γ-PGA-GMA. The mechanical property, porous structure, swelling, and degradation process of the hydrogels could be controlled by adjusting modified γ-PGA polymers component. The rheological behavior and compression test of γ-PGA hydrogels illustrated a wide processing range in addition to superb mechanical properties. These γ-PGA hydrogels showed excellent elasticity as well as toughness, withstanding more than 70% of mechanical strain. Meanwhile, the stress modulus of γ-PGA hydrogels could be up to 749 kPa. We also studied γ-PGA hydrogels as scaffolds for the 3D culture and chondrogenesis differentiation of rabbit bone marrow-derived mesenchymal stem cells (BMSCs) in vitro . In a rabbit auricular cartilage defect model, BMSCs-laden hydrogel effectively promoted chondrogenesis. Based on these findings, biomimetic γ-PGA-based hydrogels hold promising application as favorable scaffold biomaterials for cartilage tissue regeneration.
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JOURNAL OF RARE EARTHS
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2022
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IF 4.632
Junlian Wang,Wen Xu,Jianguo Cui,Guodong Xu,Yufu Chen,Peilong Wang,Ziyong Chang
Heavy rare earth element (HREE) separation has always been a great challenge. The kind of dialkylphosphinic acids is recognized as the third generation of organophosphorous acid extractants. However, detailed relationship between β -substituent (especially when it changes from H to methyl, and further to ethyl) and their extraction behaviors and selectivity for HREEs have rarely been reported. Besides, there are also few reports on effect of γ , δ -substituent on HREE extraction and separation. In this paper, we synthesized five and collected two dialkylphosphinic acids with different β , γ , δ -substituents (from H to ethyl). These extractants were divided into two groups to discuss their extraction behaviors and selectivity for HREEs: β -substituent group (P208, INET-1, P218, USTB-1 and P227) and γ , δ -substituent group (P218, P2132 and Cyanex 272). To evaluate and compare their extractabilities, P507 was used as a reference and Tm, Yb, Lu were extracted with 0.01 mol/L of these extractants from single Tm, Yb and Lu solutions (∼4 × 10 −4 mol/L) at different initial pH. Besides, pH 0.5 Tm , pH 0.5 Yb and pH 0.5 Lu values and their differences (ΔpH 0.5 Tm–Yb , ΔpH 0.5 Yb–Lu , ΔpH 0.5 Tm–Lu ) for each extractant were given to roughly evaluate their separation performance for Tm, Yb and Lu. To further investigate the selectivity of these extractants for HREEs, Tb, Dy, Ho, Er, Tm, Yb and Lu were extracted from their mixed solution with initial pH of 4.00 at phase ratio A/O of 2:1, 1:1 or 1:2. Their HREE separation performance is mainly discussed based on the adjacent HREE separation factors ( β N+1/N ) and their average value ( β T b − L u ¯ ).
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RESEARCH ON CHEMICAL INTERMEDIATES
·
2022
·Vol. 48
·期 3
·1181-1198
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IF 3.134
Zhang Zhongze,Liu Zonghui,Gu Zhiyuan,Wen Zhe,Xue Bing
The catalytic transfer hydrogenation (CTH) reaction of ethyl levulinate (EL) with alcohol to γ-valerolactone (GVL) has been investigated over a series of Zr-based catalysts, including ZrO 2 , ZrP, Zrβ, ZrP/Hβ and ZrO 2 /HZSM-5. It is found that the simplest ZrO 2 was the most efficient for GVL production, giving an EL conversion as high as 97% and GVL selectivity of 91% after 7 h at 170 °C using 2-propanol as the hydrogen donor and solvent. The effects of reaction temperature, time and solvent on catalytic performance were investigated. Moreover, the kinetic behavior of CTH reaction of EL was also studied over ZrO 2 catalyst. The as-prepared ZrO 2 gives an Ea value of 32.9 kJ/mol, which is much lower than other catalysts in the literatures. Furthermore, those catalysts have been, respectively, characterized by XRD, IR, BET and NH 3 -TPD techniques to reveal the physical properties and structures of these materials. Correlating the catalyst performance with its physical and chemical properties uncovers that the higher pore diameter, lower total acidity and higher Lewis acid sites of catalyst surface would be the key to the catalyst performance. Graphical abstract
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CHINESE JOURNAL OF CHEMICAL ENGINEERING
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2022
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IF 3.898
Xinyu Yang,Zezhi Chen,Huijuan Gong
Catalytic oxidation of CH 4 has been proved to be an attractive option for landfill gas (LFG) upgrading. However, coking of catalysts in catalytic LFG deoxygen has been clearly observed in industrial applications. In this regard, it is necessary to investigate whether coke deposition originates from CH 4 or volatile organic compounds present in LFG, and the influence of coke deposition on catalytic performance. Herein, we evaluate the LFG deoxygen on Pt/γ-Al 2 O 3 catalyst in simulated LFG (CH 4 , CO 2 , O 2 , N 2 ) and its co-feed with representative volatile organic compounds, ethylbenzene , toluene, benzene and cyclohexane . The results show that the coking of the catalyst is originated from volatile organic compounds rather than CH 4 . The Pt/γ-Al 2 O 3 catalyst does not deactivate during LFG deoxygen process, even significant amount of coke deposited, up to 18.15% (mass). Characterization analyses reveal that although coke deposition overall covers the catalyst surface, resulting in mesopores blockage and a reduced number of accessible Pt sites, however, the coke formed, H-rich carbonaceous components, behaves as counterpart for O 2 elimination. Besides, the coke deposited is mainly filamentous. Thus, coke formation has little negative effect on the overall catalytic performance of Pt/γ-Al 2 O 3 catalyst ultimately. The results obtained in this work are helpful for the rational design of robust Pt based catalysts for LFG deoxygen without undue attention to their coking properties, and also favor the innovation of more attractive purification scheme configurations.
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MICROCHIMICA ACTA
·
2023
·Vol. 191
·期 1
·1-9
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IF 5.7
Xia Jianan,Bo Bing,Yang Shuang,Cao Yue,Cao Ya,Cui Haiyan
A new aptamer-based method has been developed for interferon-γ (IFN-γ) detection by utilizing interface reactivity-modulated fluorescent metal–organic frameworks (MOFs). Specifically, the binding of IFN-γ to its aptamer decreases the interface reactivity between the biotin-labeled aptamer and the streptavidin-functionalized magnetic beads by generating significant steric effects. As a result, several biotin-labeled aptamers escape from the enrichment of magnetic beads and remain in the supernatant, which subsequently undergo the terminal deoxynucleotidyl transferase-catalyzed polymerization elongation. Along with the elongation, pyrophosphate is continuously produced as the by-product, triggering the decomposition of fluorescent MOFs to generate a remarkable fluorescent response with the excitation/emission wavelength of 610 nm/685 nm. Experimental results show that the method enables the detection of IFN-γ in the range 0.06 fM to 6 pM with a detection limit of 0.057 fM. The method also displays high specificity and repeatability with an average relative standard deviation of 2.04%. Moreover, the method demonstrates satisfactory recoveries from 96.3 to 105.5% in serum samples and excellent utility in clinical blood samples. Therefore, this work may provide a valuable tool for IFN-γ detection and is expected to be of high potential in tuberculosis diagnosis in the future. Graphical Abstract
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Food and Bioprocess Technology
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2023
·
IF 5.6
Liu Yikun,Liao Li,McClements David Julian,Chen Xing,Cao Mengmeng,Liang Ruihong,Zou Liqiang,Liu Wei
Vanilla is one of the most widely used flavors in the food and beverage industry; however, it is thermally unstable and volatile. In this study, microparticles consisting of ternary complexes of vanillin/γ-cyclodextrin/dextran (V/C/D) were prepared, in which vanillin served as a crosslink between the γ-cyclodextrin and dextran. One end of vanillin was inserted into the interior of γ-cyclodextrin through hydrophobic interactions and hydrogen bonding, while the other end was bound to dextran through hydrogen bonding. The encapsulation efficiency of vanillin in the microparticles increased from around 59 to 92% when the mass ratio of dextran in the complexes increased (V/C/D ratio ranging from 1:9:0 to 1:5:4). Moreover, the crystallization peak of vanillin disappeared in complexes with higher dextran contents. The dispersibility of vanillin in cold water (4 ℃) increased as the dextran content in the complexes increased, with the highest value being 15 mg/mL. Encapsulation of vanillin within the microparticles protected it from volatilization during storage, with more than 90% being retained after holding at 60 ℃ for a month, as well as increasing its resistance thermal processing. The release of vanillin during baking (200 ℃, 30 min) could be controlled by altering the composition of the microparticles. Our findings provide a novel strategy for improving the stability and controlling the release of aromas. Graphical Abstract
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JOURNAL OF DISPERSION SCIENCE AND TECHNOLOGY
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2023
·
IF 2.2
Nana Sun,Jianbo Hu,Lisha Shen,Huina Sun,Ding Wang
The effects of modified γ-Fe2O3 magnetic nanoparticles having various sizes at different mass fractions on the stability of heavy oil-in-water emulsions were compared. The zeta potential, wettability, oil-water interfacial tension, apparent viscosity, and oil droplet distribution of the emulsions were measured. The optimal size of the γ-Fe2O3(-COOH) magnetic nanoparticles was 2–3 μm, and this resulted in the lowest water-separation rate (23.72% at 4 hours), greatest electrostatic repulsion, weakest hydrophilic effect, lowest interfacial tension, greatest migration resistance, and smallest and most uniform oil droplet distribution. In addition, the stability of the emulsions increased and then decreased as the mass fraction of γ-Fe2O3 (-COOH) magnetic nanoparticles increased because of the increased electrostatic repulsion and decreased migration resistance. This in-depth analysis of the effect of modified magnetic nanoparticle size on the stability of oil-in-water emulsions provides comprehensive theoretical support for achieving viscosity and resistance reduction in an environmentally friendly manner.
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FUEL
·
2023
·
IF 7.4
Biao Yang,Ke Fan,Shanshan Yu,Rongguang Yang,Linfeng Zhang,Fuqing Zhang,Weijie Chi,Huadong Wu,Jia Guo
Deep eutectic solvents (DESs) are widely used in oxidative desulfurization (ODS) to produce clean fuel. However, some DESs with good ODS efficiencies are generally consisted of harmful components, and the ODS efficiencies of most DESs with green components need to be further improved. Herein, a DES with two natural compounds of γ-valerolactone (γ-Val) and formic acid (FA) was prepared and used in ODS. The hydrogen bond interaction of DES was characterized by FT-IR, 1 H NMR, DSC, and calculated by density functional theory (DFT) computation. The radical quenching experiments, EPR, and kinetic study were carried out to investigate the active radical and apparent activation energy of ODS process. The desulfurization efficiencies of γ-Val and FA (molar ratio 1: 4) DES was capable of reaching 100% of dibenzothiophene (DBT) removal within 100 min at an energy saving way of room temperature (25 °C) with a low O/S molar ratio of 2. When the temperature was raised to 70 °C and the O/S molar ratio was raised to 5, 100% sulfur removal of dibenzothiophene, 4,6-dimethyldibenzothiophene (4,6-DMDBT), and benzothiophene (BT) could be achieved in 4 min, 6 min, and 10 min respectively. DFT calculations revealed that the introduction of γ-Val could reduce the transition state energy barrier of ODS compared with a single FA ODS process. This work provides a novel high ODS efficiency DES with natural compounds, indicating the potential application of green DESs in ODS catalysts.
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VACUUM
·
2023
·
IF 4
Zihan Wang,Xiaoqing Ma,Qiaodan Li,Xinyao Tian,Jilei Si,Mauricio A. Melo
Photoelectrochemical (PEC) water splitting is a viable method for converting renewable solar energy into storable chemical energy. Herein, the newly emerged two-dimensional sp- and sp 2 -carbon hybridized graphyne sheets were successfully coupled with thin film-like arrays of titanium dioxide nanorods , forming an efficient 2D-1D heterojunction . The microstructure and composition of obtained γ-graphyne/TiO 2 films were well characterized. And enhanced photoelectrochemical properties were demonstrated. The γ-graphyne/TiO 2 photoelectrode achieves a photocurrent density of 1.31 mA/cm 2 at 1.23 V ( vs. RHE), which is 1.7 times over that of pristine titanium dioxide. An improvement of photoconversion efficiency by 2.2 folds was observed. The high PEC activity of γ-graphyne/TiO 2 originates from band alignment and interfacial junction between π-conjugated graphyne sheets and TiO 2 nanostructure , greatly promoting charge transfer and diminishing defective excitation and recombination. By virtue of the γ-graphyne nanosheets , largely increased number of useful photons and catalytic active sites are triggered. This work provides a reference for the photoelectrochemical application of semiconductive γ-graphyne and a specific and proven method for the utilization of solar energy.
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BIOMEDICINE & PHARMACOTHERAPY
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2023
·
IF 7.5
Zhangnian Liu,Shiquan Gan,Lingyun Fu,Yini Xu,Shengquan Wang,Guangqiong Zhang,Di Pan,Ling Tao,Xiangchun Shen
1,8-Cineole, the main component of volatile oil in aromatic plants, has diverse pharmacological properties, including antioxidant, anti-inflammatory, and anti-cancer properties. Diabetic retinopathy (DR) is a common microvascular complication of diabetes mellitus (DM). Here, we investigated the protective effect of 1,8-cineole on DR and found that 1,8-cineole treatment could alter the expression of several genes in both high glucose (HG)-induced ARPE-19 cells and retinal tissues of DM mice, as well as inhibit ferroptosis. Subsequent investigations into the molecular mechanisms underlying this inhibition revealed that expression of thioredoxin-interacting protein (TXNIP) was significantly upregulated while that of peroxisome proliferator-activated receptor γ (PPAR-γ) was significantly downregulated in HG-induced ARPE-19 cells, and treatment with 1,8-cineole could effectively reverse these changes. Treatment with a PPAR-γ pharmacological agonist (rosiglitazone), alone or combined with 1,8-cineole, significantly inhibited the transcription of TXNIP and ferroptosis in HG-induced ARPE-19 cells. Conversely, pretreatment with GW9662, a PPAR-γ inhibitor, upregulated the transcription and expression of TXNIP in HG-induced ARPE-19 cells; 1,8-cineole failed to reverse this upregulated expression. To explore these relationships, we constructed a PPAR-γ adenovirus shRNA to elucidate the effect of 1,8-cineole on the negative regulation of TXNIP by PPAR-γ. Taken together, the present findings indicate that HG-induced ferroptosis in retinal tissue plays an essential role in the pathogenesis of DR, which can be ameliorated by 1,8-cineole.
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FOOD CHEMISTRY
·
2023
·
IF 8.8
Zonghan Wang,Dayong Zhou,Donghong Liu,Beiwei Zhu
Here, an ethanol-mediated method was introduced to fabricate γ-cyclodextrin-based metal–organic frameworks (γ-CD-MOFs) as microcarriers for epigallocatechin-3-gallate (EGCG). Through adjusting ethanol gas diffusion temperature and ethanol liquid feed speed, we achieved control of crystallization efficiency and crystals size without extra surfactants. Under the sequential regulatory by ethanol in two phases, the obtained γ-CD-MOFs with cubic shape exhibited excellent crystallinity, high surface area, and uniform size distribution. Through the interplay of hydrogen bonding, hydrophobic interactions and π stacking, EGCG molecules could be stored efficiently within cavities and tunnels of the γ-CD-MOFs with high load capability of 334 mg g −1 . More importantly, the incorporation of EGCG within frameworks wouldn’t disintegrate the unique body-centered cubic structure of γ-CD-MOFs, in turn, would improve the thermostability and antioxidative activity of EGCG. Significantly, all food-grade materials ensured the γ-CD-MOFs high acceptance and applicability for food and biomedical applications.
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