Materials Today Communications
·
2024
·
IF 3.7
Hao Peng,Xiaolan Song,Yi Wang,Zhipeng Cheng,Chongwei An
The nano-boron powder (n-B) exhibits remarkable efficacy as a combustion catalyst, making it a prime candidate for use in solid propellant metal burners. Nevertheless, throughout the storage phase, the surface of n-B powder is prone to oxidation and substantial agglomeration, resulting in challenges with ignition and incomplete energy dissipation when utilizing boron powder. In this study, we utilized the coaxial electrospinning technique to produce nanofibers comprised of nano-boron /nitrocellulose/ammonium perchlorate@fluororubber (n-B/NC/AP@F 2602 ), with the nano boron uniformly distributed within the core-shell fibers. In the course of combustion, the fibrous composite of n-B/NC/AP@F 2602 undergoes an escalation in the rates of energy output and energy release, owing to the constraints imposed by external F 2602 ((C₂H₂F₂) n and (C₃F₆) n ). The n-B/NC/AP@F 2602 demonstrates a 1.4-fold increase in peak pressure and a 3.6-fold increase in maximum boost rate when compared to the n-B/NC/AP. The energy performance evaluation results reveal that the mean molecular weight (MC) of combusted products from n-B/NC/AP@F 2602 is 29.2 g·mol −1 , representing a substantial increase compared to that of n-B/NC/AP. The aforementioned findings exemplify that coaxial electrospinning is an exceedingly efficacious technique for enhancing nanostructures, thereby amplifying the reactivity of energetic particles and offering novel insights into their application in energetic materials.
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Journal of Materials Chemistry B
·
2025
·
IF 5.7
Wei Wang,Ensi Liu,Jinxia Wang,Jianfeng Li,Sen Lin,Xifan Mei
Spinal cord injury (SCI) encompasses a series of pathophysiological processes, including inflammation, apoptosis, autophagy, and pyroptosis, leading to an imbalance in the microenvironment. The microenvironment following injury inhibits axonal regeneration, ultimately resulting in the loss of neurological function. Among these pathological processes, inflammation plays a critical role in the recovery from SCI. The inflammatory cascade triggered by SCI leads to cell apoptosis, cell death, and impaired angiogenesis, which collectively hinder axonal regeneration. In recent years, nano-enzymes exhibiting Prussian blue enzyme-like peroxidase activity have garnered significant attention as alternatives to natural enzymes in therapeutic applications, biosensing, and environmental remediation. Schisandra, a traditional Chinese medicine, contains schisantherin B as its principal component, which has been reported to possess neuroprotective effects in various neurological diseases. In this study, we designed a Prussian blue nanozyme drug delivery system, a schisantherin B-loaded Prussian blue nanozyme (SchB@PBzyme), for the treatment of SCI. Our findings indicate that the SchB@PBzyme significantly suppresses the inflammatory response and promotes neural remodeling, thereby offering a novel treatment strategy for SCI.
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PubMed
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Targeted Oncology
·
2020
·Vol. 15
·期 3
·365-375
·
IF 4.036
Ding Shengnan,Mao Xia,Cao Yang,Wang Na,Xu Hao,Zhou Jianfeng
Background Although chimeric antigen receptor (CAR) T-cell therapy targeting antigens expressed in refractory and relapsed non-Hodgkin B-cell lymphoma, such as CD19 and CD22, has achieved encouraging clinical effects, some patients fail to attain remission, or relapse after CAR T-cell therapy, which has been ascribed to the loss of the target antigens. Objective To evaluate CD79b as an alternative target for CAR T-cell B-cell lymphoma therapy. Patient and methods The expression of CD79b in different B-cell lymphomas was determined. Anti-CD79b CAR T-cells expressing one of two different CARs were generated, and a series of in vitro and in vivo experiments were conducted to assess the CAR T-cell function. Results We found that CD79b was extensively expressed on the tumor cells of patients with various types of lymphoma regardless of stage, subtype, and cytogenetic and molecular features. Anti-CD79b CAR T-cells were highly specific and effective for the treatment of B-cell lymphomas. Conclusions Our data indicate that CD79b could be used as a target for CAR T-cell therapy of B-cell lymphomas, and further clinical development is warranted.
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JOURNAL OF ALLOYS AND COMPOUNDS
·
2025
·
IF 6.3
Yaqi He,Xinhua Li,Zhu Qian,ZuPeng Yan,Guizhen Shi,Xia Sun,Zongqing Ma
In this paper, we innovatively introduced Sn and B into the Nb-Al system at the same time and successfully prepared high-performance Nb 3 Al bulks through mechanical alloying and subsequent low-temperature sintering processes. The influence of different doping amounts of B in the Sn-B co-doping on the superconducting properties of Nb 3 Al superconductors was also investigated. It was found that Sn-B co-doping greatly improves the superconducting properties of Nb 3 Al, especially the J c properties, compared with the undoped sample. The optimal doping amount of Sn-B co-doping is finally determined to be 4 at% Sn-2.6 at% B. At this time, the superconducting transition temperature of Nb 3 Al is up to 16.2 K, and the critical current density reaches up to 1.3 × 10 5 A⋅cm −2 (4.2 K, 5 T), which is almost twice higher than that of Sn-doped Nb 3 Al, and one order of magnitude higher than that of general undoped Nb 3 Al. Combined with the phase composition analysis and microstructure observation, we find that with the co-doping of Sn and B, the grain size of Nb 3 Al is refined, and the diffusely distributed Nb 2 Al nanoparticles are introduced, which greatly enhance the magnetic flux pinning effect of Nb 3 Al. Secondly, the intergranular connectivity of Nb 3 Al is significantly improved. The Sn-B co-doped Nb 3 Al superconductors combine the advantages of Sn doping to enhance flux pinning and B doping to improve intergranular connectivity, which synergistically promotes the dramatic improvement of Nb 3 Al superconductivity Nb 3 Al.
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JOURNAL OF SOLID STATE CHEMISTRY
·
2025
·
IF 3.5
Xuezhen Zhai,Xiaohong Chen,Yongqi Wu,Xuzhe Wang,Cui Shang,Lamei Zhang,Chengzhou Zhao,Huawei Zhang,Jimin Shang,Dewei Liu
The VO 2 (B) cathode materials maintain high stability during the zinc ion embedding/removal process, making it a research hotspot in positive electrode materials for water-based zinc ion batteries . However, its poor ion diffusion kinetics and intrinsic semiconductor properties have become the main reasons limiting the enhancement of the specific capacity and rate performance. Herein, the function of Co-doping on the microstructure, morphological characteristics, transport characteristics and electrochemical performances of the Co x V 1- x O 2 (B) nanorods were comparatively investigated. The Co 0.05 V 0.95 O 2 (B) cathode has the highest specific capacity and unmatched cycle stability. The optimized electrochemical performance was mainly due to the synergistic optimization of grain distortion, grain size and oxygen vacancy inside the lattice. The electrochemical kinetics results show that the Co 0.05 V 0.95 O 2 (B) cathodes were capacitor and battery hybrid characteristics. The above conclusions provide a good idea and experimental verification for applying VO 2 (B) cathode in the water-based zinc ion batteries market.
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FASEB JOURNAL
·
2022
·Vol. 36
·期 9
·e22468
·
IF 5.834
Chujie Ding,Yu Hong,Yuan Che,Tianyu He,Yun Wang,Shule Zhang,Jiawei Wu,Wanfeng Xu,Jingyi Hou,Haiping Hao,Lijuan Cao
Cholestasis is a common complication of hepatitis B virus (HBV) infection, characterized by increased intrahepatic and plasma bile acid levels. Cholestasis was found negatively associated with hepatitis outcome, however, the exact mechanism by which cholestasis impacts anti-viral immunity and impedes HBV clearance remains elusive. Here, we found that cholestatic mice are featured with dysfunctional T cells response, as indicated by decreased sub-population of CD25 + /CD69 + CD4 + and CD8 + cells, while CTLA-4 + CD4 + and CD8 + subsets were increased. Mechanistically, bile acids disrupt intracellular calcium homeostasis via inhibiting mitochondria calcium uptake and elevating cytoplasmic Ca 2+ concentration, leading to STIM1 and ORAI1 decoupling and impaired store-operated Ca 2+ entry which is essential for NFAT signaling and T cells activation. Moreover, in a transgenic mouse model of HBV infection, we confirmed that cholestasis compromised both CD4 + and CD8 + T cells activation resulting in poor viral clearance. Collectively, our results suggest that bile acids play pivotal roles in anti-HBV infection via controlling T cells activation and metabolism and that targeting the regulation of bile acids may be a therapeutic strategy for host-virus defense.
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SURFACE & COATINGS TECHNOLOGY
·
2021
·
IF 4.158
Yihan Zhang,Shihong Zhang,Yi He,Hongjie Li,Teng He,Yi Fan,Huili Zhang
Ni-B/B 4 C composite coatings on N80 steel were achieved by pulsed electrodeposition (PED). The optimal condition for obtaining composite coating is investigated via studying the effects of different content B 4 C on the performance of Ni-B/B 4 C coatings, including the surface morphology , microstructure, hardness and electrochemical properties . Scanning electron microscopy (SEM), X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS) and energy dispersive spectrometer (EDS) were used to analyze the surface morphology, crystal morphology and element type and content of the composite coatings. The hardness of coatings was investigated by micro-hardness test. The electrochemical properties of coatings were demonstrated by electrochemical impedance spectroscopy (EIS) and scanning electrochemical microscope (SECM). Results show that the grain was uniformly deposited on the surface of N80 steel, and no pinholes and microcracks were captured. Besides, the average Vickers hardness of the Ni-B/B 4 C was the highest (1030.61 HV), and the average coefficient of friction (COF) is 0.22 (the average COF of Ni-B is 0.49). In 3.5 w % NaCl solution, Ni-B/B 4 C (2 g L −1 ) exhibits good corrosion resistance , with a corrosion voltage of − 0.30 − 0.010 + 0.010 V, and a corrosion current of − 1.15 − 0.220 + 0.219 μA.
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ADVANCED POWDER TECHNOLOGY
·
2019
·
IF 3.25
Cuiling Ai,Sikai Yang,Fan Zhang,Xiangwen Shao,Junge Xu
Ag/AgCl-GO composite was fabricated by deposition–precipitation method and photoplasmic reduction method at room temperature. The resulting products were characterized by XRD, XPS, SEM, TEM, Zeta potential and UV–Vis DRS. The results indicated that the samples were composed of Ag, AgCl and graphene oxide (GO). During the photoreduction, the crystallinity of Ag 0 particles gradually increased with prolonging the time of UV irradiation, then remained stable after 90 min. The addition of GO had little effect on the crystal structure of Ag/AgCl, however, this reduced the particle size and enhances the dispersibility of the composite. After 100 min of visible light irradiation, the degradation efficiency of rhodamine B (RhB) reached 98.43%. Therefore, the Ag/AgCl-GO photocatalyst exhibited significant photocatalytic activity during the degradation of RhB under visible light.
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Russian Journal of Physical Chemistry A
·
2014
·Vol. 89
·期 2
·291-296
·
IF 0.488
Sun C. H.,Wang M. L.,Feng Q.,Liu W.,Xu C. X.
The SERS signals of Rhodamine B (RhB) adsorbed on Ag, ZnO, and Ag-capped ZnO (ZnO/Ag) substrates were studied. Comparative analysis indicated no significant difference in the positions of the peaks, but the intensities of SERS signals are different. However, abnormal Raman spectrum of RhB (10 −4 M) adsorbed on ZnO was observed, which was different from the normal Raman spectrum distinctly. By assignment of the vibrational bands of abnormal Raman spectrum, it is suggested that the nitrogen atom is primarily adsorbed on the ZnO substrate instead of the xanthene ring.
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CHEMISTRY OF MATERIALS
·
2019
·
IF 10.159
Ziyan Wu,Qiqi Zhang,Binghan Li,Zhifang Shi,Kaimin Xu,Yi Chen,Zhijun Ning,Qixi Mi
All-inorganic metal halide perovskites are noted for their excellent optoelectronic properties and good chemical stability but also a propensity to transform into nonperovskite phases. A case in point is lead-free CsSnCl3, whose perovskite Phase I is metastable at room temperature and could not be stabilized by partial substitution of Cs+ or Cl–. Judging from the radii of the constituent ions of CsSnCl3, we paid attention to octahedral cations smaller than Sn2+ and selected Mn2+ and In3+ for substitution at the B-site. A quantitative structural indicator, volume per formula unit (V/Z), guided the syntheses of CsSn0.9Mn0.1Cl3 (CTMC) and CsSn0.9In0.067Cl3 (CTIC), which are shown by single-crystal X-ray diffraction and differential scanning calorimetry to be homogeneous, stable perovskite phases at room temperature. CTMC turns into a disordered perovskite structure at 193 K, lower than the corresponding transition temperature of CsSnCl3 by nearly 100 K. Vacancies in CTIC result in a more flexible crystal structure than CTMC and CsSnCl3. CTMC and CTIC appear bright yellow with a steep absorption edge at ∼450 nm, and their photoluminescence peaks are located at 645 and 484 nm, respectively, with intensities significantly enhanced from CsSnCl3. Energy transfer processes are proposed to account for the Stokes shifts in the photoluminescence of CTMC and CTIC. Thin films of CTMC glow red under ultraviolet excitation and hold promise for electroluminescence devices. This study gives insights into the structural and electronic effects of ionic substitution in CsSnCl3 and can be extended to other metastable perovskite phases.
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Waste and Biomass Valorization
·
2016
·Vol. 8
·期 4
·1371-1378
·
IF 0.915
Zhao Wenfeng,Yang Tingting,Li Hu,Lu Yemin,He Jian,Liu Yanxiu,Yang Song
A series of hydroxylated mesoporous aluminum–boron catalysts with different Al/B molar ratios were synthesized through a sol–gel method, and were characterized by XRD, FT-IR, NH 3 -TPD, SEM and N 2 adsorption–desorption techniques. It was demonstrated that hydroxylated Al 2 B 3 containing more Lewis acidity showed superior activity to the other Al – B catalysts in dehydration of glucose to 5-hydroxymethylfurfural (HMF) with a high yield of up to 39.9 % and glucose conversion of 92.1 % at 140 °C for 2 h. The synergistic effect of Lewis and Bronsted acid sites in Al 2 B 3 catalyst was demonstrated to be crucial for efficient conversion of glucose to HMF.
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JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
·
2020
·
IF 4.192
Yun Ma,Zhi Ma,Xiyue Huo,Meiyu Gu,Sainan Ma,Yu Jing,Yixiao Wang,Ying Yue,Zhibiao Feng,Bo Tian
The estimation of yeast viability with B- and N-doped carbon dots (BN-CDs) was investigated in this paper. BN-CDs with a fluorescent quantum yield of 65.47% were prepared by a one-step hydrothermal method. The size distribution of BN-CDs was relatively narrow, with the majority falling within 7.5–8.5 nm, and they were mainly composed of carbon, oxygen, nitrogen, and boron. BN-CDs were shown to have strong and stable fluorescence. They exhibited excitation-independent photoluminescence property, which could avoid the autofluorescence and limitation of the excitation source. Dead and live yeast cells were distinguished well by BN-CD staining in a short time, and there was no strict requirement for light protection. The application of BN-CDs in beer brewing can solve the problem of estimation of yeast viability.
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