FLAVOUR AND FRAGRANCE JOURNAL
·
2017
·Vol. 33
·期 2
·160-165
·
IF 1.644
Jia Song,Hongling Chen
The formation of apple aroma microcapsules was achieved by sodium alginate (SA) and tetradecylallydimethylammonium bromide (TADAB) as shells based on complex coacervation-emulsion polymerization. Alkyl alcohol polyoxyethylene ether was employed as emulsifier. Pentaerythritol tetraacrylate (PETRA) was used as a crosslinking agent and methyl methacrylate (MMA) was applied as comonomer to copolymerize with TADAB. The aroma microcapsules were characterized by scanning electron microscopy (SEM). Results showed that the aroma microcapsules prepared under optimal conditions were core-shell structure. The aroma microcapsules were sphere-like shape with particle size between 20 to 50 μm. FT-IR analysis results showed that the electrostatic interactions and polymerization occurred assuredly. TG-DTA study indicated that the thermal stability of the aroma microcapsules crosslinked with MMA shell was improved, and the thermal resistant temperature was up to 110°C. Moreover, the encapsulation efficiency of aroma microcapsules was measured by ultraviolet–visible near-infrared spectrophotometer. In the surfactant solution, the release of aroma was quick during the first 8 hours, losing ca . 10.8% aroma encapsulated, however, there was no more else aroma dissolving out from the 9 th hour. In open conditions, the encapsulation efficiency of the aroma microcapsules kept 66.57% after 48 hours, compared with the encapsulation efficiency going down alone if the microcapsules were milled.
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JOURNAL OF THE ELECTROCHEMICAL SOCIETY
·
2015
·Vol. 162
·期 7
·H486
·
IF 3.266
Liping Bao,Jiangying Dai,Lin Yang,Jianfeng Ma,Yongxin Tao,Linhong Deng,Yong Kong
Enantiorecognition of tyrosine (Tyr) enantiomers is realized via chiral ligand exchange technology combined with electrochemistry. A natural polymer, sodium alginate (SA), is electrodeposited on a glassy carbon electrode (GCE) and adopted as the chiral selector to form a diastereoisomeric ternary complex of [(SA)Zn(II)(L-Tyr)] or [(SA)Zn(II)(D-Tyr)] in the presence of Zn(II). Due to the difference in steric hindrance during the formation of these two complexes, the chiral selector preferentially recognizes D-Tyr. The electrochemical enantiorecognition of Tyr enantiomers is characterized by cyclic voltammetry and electrochemical impedance spectroscopy (EIS), and the parameters affecting the recognition efficiency are also investigated.
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JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
·
2013
·
IF 2.906
Kai Liu,Xinxing Lin,Lihui Chen,Liulian Huang,Shilin Cao,Huangwei Wang
The nonantibacterial and low strength properties of sodium alginate films negatively impact their application for food packaging. In order to improve these properties, a novel chitosan–benzalkonium chloride (C–BC) complex was prepared by ionic gelation using tripolyphosphate (TPP) as a coagulant, and a biocomposite obtained through the adsorption of C–BC complex on microfibrillated cellulose, MFC/C–BC, was then incorporated into a sodium alginate film. The TEM image showed that the C–BC nanoparticles were spherical in shape with a diameter of about 30 nm, and the adsorption equilibrium time of these nanoparticles on the surface of MFC was estimated to be 6 min under the driving forces of hydrogen bonds and electrostatic interactions. According to the disc diffusion method, the MFC/C–BC biocomposite-incorporated sodium alginate film exhibited remarkable antibacterial activity against Staphylococcus aureus and certain antibacterial activity against Escherichia coli. The strength tests indicated that the tensile strength of the composite sodium alginate film increased about 225% when the loading of MFC/C–BC biocomposite was 10 wt %. These results suggested that the MFC/C–BC biocomposite-incorporated sodium alginate film with excellent antibacterial and strength properties would be a promising material for food packaging, and the MFC/C–BC may also be a potential multifunctional biocomposite for other biodegradable materials.
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Journal of Materials Chemistry B
·
2013
·Vol. 1
·期 43
·5933-5941
·
IF 0
Hua Guo,Chengling Yang,Zhenpeng Hu,Wei Wang,Yukun Wu,Quanyong Lai,Zhi Yuan
The high viscosity of sodium alginate (ALG) causes its insufficient drug loading and limits its application as a drug carrier. In the present work, we synthesized poly(ethylene glycol) oligomer (mOEG)-modified sodium alginate (ALG–mOEG) and characterized its properties as a drug delivery system. Our results showed that ALG–mOEG displayed a greatly reduced viscosity (0.024 Pa s at 2.0 wt%) with a significantly improved drug loading capacity (18.0% (w/w)) compared with unmodified ALG (6.9% (w/w)). In addition, DOX–ALG–mOEG nanoparticles (DOX–ALG–mOEG NPs) with high drug loading were more cytotoxic for HepG2 cells in vitro and showed a higher antitumor activity in vivo compared with the control group (DOX–ALG NPs) at the same dose of DOX. DOX–ALG–mOEG NPs inhibited HepG2 proliferation in vitro with an IC50 value of 220.0 ng mL−1 and reduced tumor growth in vivo by 75.6%, while DOX–ALG NPs showed activities of 443.9 ng mL−1 and 62.7%, respectively. Meanwhile, we did not observe the “accelerated blood clearance (ABC)” phenomenon in these mOEG-modified ALG nanoparticles. In view of most biologic and chemical molecules used for the biological function being hydrophobic, we thought the ALG–mOEG scaffold also might serve as an efficient long-duration carrier for other hydrophobic molecules with minimal immunogenicity.
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Journal of Materials Chemistry B
·
2017
·Vol. 5
·期 12
·2337-2346
·
IF 4.543
Cheng Gao,Fan Tang,Jianxiang Zhang,Simon M. Y. Lee,Ruibing Wang
To enhance selective drug release and overcome undesired side effects, novel disulfide crosslinked sodium alginate nanoparticles were designed for achieving glutahione triggered drug release in tumor cells. The doxorubicin loaded crosslinked nanoparticles (DOX-NPs) demonstrated selective drug release in 10 mM glutathione and the further study of their cellular uptake and intracellular release confirmed that the crosslinked nanoparticles could be easily taken up and they only released the encapsulated therapeutic payload in cancer cells. The in vitro cytotoxicity of crosslinked DOX-NPs showed a selective and remarkable cytotoxic effect on Hep-G2 and HeLa cells, instead of on healthy human liver L-O2 cells. More interestingly, the otherwise cardiotoxic DOX showed no cardiotoxicity when formulated as crosslinked DOX-NPs, in an in vivo zebrafish model. This study has demonstrated that the disulfide crosslinked nanoparticle system may provide a promising drug delivery platform for selective drug release in cancer cells with a much improved safety profile.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2024
·
IF 7.7
Jie Song,Lijun Chen,Yingnan Zhou,Zhiwen Yuan,Yuhua Niu,Zhiqiang Wei
With the rapid development of industrialization, the removal of heavy metal ions and small organic molecules from wastewater has triggered a hot debate. ZIF-8 was grown on a sodium alginate backbone using an in situ growth technique, the core-shell P-SMG@ZIF-8 was synthesized. It was also characterized by FTIR, XRD, SEM, UV–Vis and XPS, and the optimal conditions and mechanism of adsorption were explored. At pH 2.0, a contact time of 200 min, and 298 K, removal of Cu(II) and Ph up to 80.2 %, 65.6 % by P-SMG@ZIF-8, adsorption behavior consistent with Langmuir model for pseudo-secondary rates, the saturated adsorption of Cu(II) and Ph could reach up to 83.5812 mg/g and 78.1779 mg/g, respectively. And the adsorbed P-SMG@ZIF-8 is easy to separate and reusable, which is a cost-effective and efficient natural product-based adsorption material.
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CHEMICAL ENGINEERING JOURNAL
·
2024
·
IF 13.3
Po-Hsiang Chang,Yating Yang,Yaqi Wen,M.M.M. Ahmed,Jou-Chieh Chang,Ting-Yu Chang,Yu-Min Tzou,Zhaohui Li,Ahmed I. Osman
This study explores the efficacy of sodium alginate/graphene oxide (SA/GO) composite beads for ethidium bromide (EtBr) removal from aqueous solutions. GO was synthesized and crosslinked with SA to design composite beads, which were evaluated under various physicochemical conditions. Characterization techniques, including FESEM, TGA, XRD, and FTIR, were employed to analyze the beads before and after EtBr adsorption. Results demonstrated rapid EtBr adsorption onto SA/GO, following the Freundlich isotherm model with a maximum adsorption capacity of 2.97 mmol g −1 (1171.05 mg g −1 ). The influence of solution pH and the negligible role of Br − ions suggested that electrostatic interaction was the primary mechanism for EtBr adsorption on SA/GO. XRD and FTIR analyses revealed that EtBr adsorption also occurred in the interlayer space of SA/GO beads, with the ethidium cations (Et + ) entering this space in a horizontal or oblique (≥45°) orientation. The accumulation of Et + within the interlayer space was estimated to form 1–6 basic inclined layers. SA/GO beads demonstrated promising characteristics for EtBr pollutant treatment, including low environmental impact, cost-effectiveness, rapid adsorption kinetics, and high removal efficiency. This study provides valuable insights into the adsorption mechanisms and performance of SA/GO beads, highlighting their potential for future field applications in the environmental remediation of EtBr contamination.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2024
·
IF 7.7
Hui Wang,Kun Dai,Houle Xiang,Jingwei Kou,Han Guo,Hanjie Ying,Jinglan Wu
Dyes are indispensable for the rapid development of society, but untreated dye wastewater can threaten human health. In this study, an adsorbent (SA/SL/CCS/PEI@MNPs) was synthesized by one-pot method using magnetic nanoparticles (MNPs), sodium alginate (SA), sodium lignosulfonate (SL), carboxylated chitosan (CCS) and polyethyleneimine (PEI). The adsorbent was mesoporous micrometer-sized particles with pore size of 34.92 nm, which was favorable for dynamic column experiments. SA/SL/CCS/PEI@MNPs possessed pH-responsive performance. Under acidic condition, the maximum adsorption capacities for anionic dyes (tartrazine, reactive black-5, indigo carmine) reached >550 mg/g. Under alkaline condition, those for cationic dyes (methylene blue, methyl violet, neutral red) exceeded 1900 mg/g. The function of the various modifiers was investigated. The results indicated that the incorporation of SL, CCS and PEI was able to provide plenty of sulfonate, carboxylate and amino/imine reactive groups so that adsorption capacities of dyes were improved. The adsorption mechanism was explored by FTIR and XPS. At the same time, the adsorption mechanism was more deeply analyzed using molecular dynamics simulations and radial distribution function. It was demonstrated that the dyes adsorption on the SA/SL/CCS/PEI@MNPs was mainly due to electrostatic attraction and π-π interaction. In addition, the adsorbent had good reusability, and the removal still reached over 90 % after five cycles. In conclusion, the adsorbent displayed a broad prospect for the adsorption of organic dyes.
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COMPOSITES SCIENCE AND TECHNOLOGY
·
2025
·
IF 9.8
Zheng Jiang,Zhaosen Yuan,Yiming Zhao,Chengshu Xu,Qian Wang
As electronic devices advance towards higher performance and miniaturization, the demand for flexible thermal interface materials has significantly increased. Liquid metal (LM) is considered an ideal conductive filler of polymer materials due to its superior thermal properties and fluidity. However, LM’s electrical conductivity makes achieving insulation in LM-polymer composites with high LM content challenging. This study introduces a novel method for preparing uniform dispersion, high thermal conductivity yet non-conductive LM composite films. This method involves pre-coating LM microspheres using sodium alginate microcapsule before incorporating them into a polyurethane matrix. This approach effectively overcomes the inherent challenges associated with the uniform distribution of LM in polymers, such as leakage and uneven dispersion, thereby significantly enhancing the stability and filler loading of LM. Even when stretched, the LM microcapsules will not be broken. Through this technique, we successfully increased the LM loading to 80 wt%, while preserving the mechanical integrity and electrical insulation properties of the composite. The thermal conductivity of the composite increased from 0.17 W/mK to 1.59 W/mK, significantly surpassing that of unmodified polyurethane. The electrical resistivity was measured as 1.1 GΩ·m under normal conditions and remains high even under 300% elongation. Furthermore, the surface properties of the composite have been investigated, revealing that its hydrophobicity decreased as the microcapsule content increased. This study adeptly achieves a synergistic balance between high filler loading and the enhancement of thermal, electrical, and mechanical properties, making it ideal for the demanding specifications of high-performance electronics and advanced energy systems.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2024
·
IF 7.7
Ayman K. El-Sawaf,Abdelrahman M. Abdelgawad,Amal A. Nassar,Dalia A. Elsherbiny
The increasing threat of spoilage bacterial infections, driven by the resistance of bacteria to many antimicrobial treatments, is a significant worldwide public health problem, especially concerning food preservation. To tackle these difficulties, this research investigates the possibility of using packaging sheets that include antimicrobial agents and increasing the prolonged storage time by preventing the bioburden of foodborne pathogens . This approach uses metal nanoparticles' ability to prevent harmful bacteria that cause food spoiling. Gallium nanoparticles (GaNPs) were created using a water-based extract from Andrographis paniculata leaves as a bioreducing agent. The GaNPs were added to a film made of sodium alginate (SA) and polyvinylpyrrolidone (PVP). The study showed that incorporating GaNPs into polymer films resulted in films with a desirable contact angle and decreased water vapor permeability. Significantly, the developed films demonstrated increased efficiency against E.coli O157 compared to other species. Also, it exhibited increased vulnerability to bacterial strains at the biofilm stage, surpassing PVP-SA/GaNPs-0. Remarkably, the toxicity tests showed that the films exhibited no cytotoxicity. Overall, the films indicated their potential for avoiding bacterial bioburden, prolonging the shelf life of perishable products , and contributing to diverse antimicrobial applications in the food industry.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2025
·
IF 8.5
Simin Wang,Bei He,Siyang Li,Zihuan Hou,Xiaolin Shang,Daodao Hu,Jing Wang,Yujia Luo,Xiaolian Chao,Yuhu Li,Junli Ren,Huiping Xing
The long-term fixation of mineral pigments in ancient paintings has always been a challenge. Gelatin alum solution (GAW), as a traditional pigment fixative, presents good pigment fixation in the early stage of use, but its poor durability is well known. In this work, a microgel (SH 1:1 ) prepared from sodium alginate and hydroxyethyl cellulose was proposed to replace GAW for the pigment fixation due to its micro scale, strong adhesion, and good chemical stability. The evaluation results indicate that SH 1:1 microgel can endow the treated unstable pigment samples with better fixation effect and durability. Especially after 10 days of temperature humidity alternating aging, the SH 1:1 treated samples show smaller morphological changes and higher retention rates of tensile strength and folding endurance (98.5 % and 79.2 %) than those of GAW treatment (96.5 % and 46.5 %). The excellent fixation effect is attributed to SH 1:1 microgel's strong bonding strength to mineral pigments and paper fibers. Moreover, the outstanding durability is due to the good aging resistance, water retention and mild alkalinity (pH = 7.0–7.5) conferred by SH 1:1 treatment, preventing rapid failure of fixative, as well as preventing paper acidification and degradation. Therefore, SH 1:1 microgel has great application potential in restoring antique paintings.
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LWT-FOOD SCIENCE AND TECHNOLOGY
·
2025
·
IF 6.6
Xiaohan Wang,Shujin Chen,Xirui Zhang,Bin Liang,Xiulian Li,Yan Li,Chanchan Sun
Lactobacillus plantarum ( L. plantarum ) was embedded in pea protein isolation (PPI)/sodium alginate (SA) composite microgels prepared by double crosslinking with transglutaminase (TGase) concentration of 10.0 U/g PTN and calcium chloride (CaCl 2 ) concentrations of 0, 0.05, 0.10, 0.15, 0.20, and 0.25 g/L, respectively. The influence of the CaCl 2 concentration on the structure, physicochemical properties, and functional properties of the composite microgels was investigated to reveal the conformational relationship between the structure and the delivery effect of encapsulated probiotics. The results showed that higher concentrations of CaCl 2 favoured the unfolding and aggregation of proteins through hydrophobic interactions and Ca 2+ bridges, thus increasing gel strength and mechanical properties, as well as enhancing thermal stability. When CaCl 2 was added up to a concentration of 0.20 g/L, the encapsulation efficiency (EE) of microgels reached a maximum of 92.62 ± 1.90%. During in vitro digestion, the resistance of the composite microgels to simulated gastric fluid (SGF) increased with rising CaCl 2 concentration, whereas the number of viable bacteria released in simulated intestinal fluid (SIF) decreased. After 120 minutes of immersion in the intestinal fluid, PS-Ca 2+ 2.0% released the least number of viable bacteria at 4.10×10 8 CFU/g than other double-crosslinked microgels, which can avoid the premature release of probiotics in the small intestine, and was conducive to realize the colon-targeted delivery of probiotics. Overall, the structural and functional enhancements achieved by CaCl 2 addition highlight the potential of PPI-SA composite microgels for probiotic protection and delivery.
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