INORGANIC CHEMISTRY
·
2026
·Vol. 65
·期 34
·19902-19910
·
IF 4.6
Feng Xinlian,Zhu Ting,Wu YuChi,Ji Shumin,Ji Yadong,Yu Zhongwei,Zhang Nan,Yin Shuhu,Xu Jun
Developing efficient and durable electrocatalysts toward
the acidic
oxygen evolution reaction is crucial for the advancement of renewable
hydrogen energy technologies. Ruthenium dioxide stands out as one
of the most promising acidic OER catalysts. However, the unsatisfactory
stability of RuO 2 and the sluggish proton-coupled electron
transfer kinetics of OER hinder its practical application. Herein,
we introduce Se doping to form a Se–Ru–O asymmetric
configuration into RuO 2 to tailor electron redistribution
and achieve both high activity and stability. The obtained Se-RuO 2 shows superior electrocatalytic activity with a small overpotential
of 212 mV at 10 mA cm –2 and a long durability of
230 h. Electrochemical tests and density functional theory calculations
demonstrate that Se-RuO 2 exhibits enhanced deprotonation
kinetics and optimized adsorption energy of reaction intermediates,
thereby boosting OER activity. Morever, the electronic interactions
mediated by the asymmetric Se–Ru–O bond diminish the
covalency of Ru–O bonds and thus boost the stability of RuO 2 . This work offers a facile strategy for the development of
high-performance catalysts incorporated with nonmetallic elements.
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高影响因子
ACS Applied Materials & Interfaces
·
2025
·
IF 8.2
Zhe Li,Zeyang Li,Hao Lu,Boyu Song,Xiya Zhao,Hanyang Zhou,Lei Wang,Qingli Zou,Yusen Yang,Min Wei
Tin oxide is widely recognized as a promising candidate for the electrochemical synthesis of formate from CO2. However, challenges such as suboptimal performance and a limited understanding of the reaction mechanisms persist. In this study, we developed an integrated electrode by optimizing a hierarchical metal–metal oxide nanoarray via a combination of hydrothermal synthesis and electrodeposition. This design enables direct growth of the catalyst on the current collector, eliminating the need for polymer binders. The constructed metal–loading structure effectively regulates the electronic structure of Sn and facilitates the formation of Snδ+ species, which thereby enhances the adsorption strength of *OCHO intermediate, significantly enhancing formate production. The resulting electrocatalyst, Bi–Sn(In)O, demonstrates a Faradaic efficiency (FE) of 83.66% for the reduction of CO2 to formate, with a maximum production rate of 768.12 μmol·h–1·cm–2 and a current density of 54.45 mA·cm–2. In situ infrared characterization and theoretical calculations reveal that local charge redistribution and the presence of high-valence Snδ+ improve the adsorption and stabilization of the crucial *OCHO intermediate, thereby lowering the energy barrier for HCOOH formation. Additionally, the integrated electrode design enables the exposure of more active sites, substantially increasing the electrochemical surface area and catalytic activity. This study offers valuable insights into the catalyst design for high-valence Snδ+ in CO2 reduction.
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ACS Synthetic Biology
·
2025
·
IF 3.9
Zhen Zong,Lianghua Xie,Jiaqi Fu,Zhongyang Liu,Wen-Wen Zhou,Wei Chen
Cyanidin-3-O-galactoside (C3Ga), a natural pigment, has various beneficial biological activities and is widely used as a food colorant. However, traditional plant extraction methods are time-consuming and unsustainable. Rapid and sustainable synthesis of C3Ga by engineered microorganisms offers a promising alternative to traditional plant-based methods and deserves to be explored. In this study, the bioproduction of C3Ga by Escherichia coli was achieved for the first time. The biosynthetic pathway of C3Ga from (+)-catechin was constructed by introducing anthocyanidin synthase (ANS) and UDP-galactose:cyanidin galactosyltransferase. Some strategies, including enhancement of the UDP-galactose biosynthesis pathway, identification of efficient ANS, overexpression of the C3Ga transporter, and modulation of multigene expression, were subsequently used to drive the metabolic flux toward C3Ga production. Next, the two-stage process for C3Ga production was optimized to mitigate limitations for further metabolic engineering. Combined with the knockout of β-phosphoglucomutase (ycjU), a newly identified competitive pathway for UDP-galactose, the production of C3Ga finally reached 217.9 mg/L. The strategies used in this study could be applied to the biosynthesis of other anthocyanins and galactosylated natural products.
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Journal of Environmental Chemical Engineering
·
2025
·
IF 7.2
Qiming Li,Hongli Wang,Boran Yang,Yunwei Zhang,Yan Liu,Jinhan Xie,Chengxu Wang,Lixin Chen,Gaofeng Han
With the growing emphasis on sustainable energy and carbon-neutral strategies, the efficient utilization of alcohol has attracted increasing attention. Direct ethanol fuel cells (DEFCs), which convert ethanol into electricity, offer a nontoxic, environmentally friendly, and efficient pathway for green alcohol valorization. The commercialization of DEFCs critically depends on the development of highly active and durable electrocatalysts for the ethanol oxidation reaction (EOR). In this work, we report a green and facile self-reduction method to synthesize surface-clean AuPd alloy nanoparticles (NPs) uniformly anchored on nitrogen and oxygen co-doped porous carbon sheets (AuPd/NOPCS), without the use of external reductants, surfactants, or organic solvents. The high porosity and low reduction potential of NOPCS facilitate the formation of well-dispersed NPs on NOPCS. The resulting AuPd/NOPCS exhibits a significantly enhanced EOR mass activity of 12.68 A mg Pd −1 , surpassing that of commercial Pd/C (1.96 A mg Pd −1 ), AuPd/OPCS (1.81 A mg Pd −1 , OPCS defined as oxygen doped porous carbon sheets), and Pd/NOPCS (4.16 A mg Pd −1 ). Density functional theory (DFT) calculations further reveal that the superior EOR performance of AuPd/NOPCS due to optimized electronic interactions and reduced intermediate adsorption. This work not only advances the rational design of efficient EOR electrocatalysts but also contributes to the broader goal of clean energy production from alcohols.
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Advanced Science
·
2025
·
IF 14.1
Lili Liu,Chen Wang,Luxin Zhao,Yayun Xiao,Weiwei Fang,Lanling Zhao,Faxing Wang,Yuping Wu
The practical development of Li-O 2 batteries (LOBs) urgently needs to explore robust cathode catalysts to boost the sluggish Li 2 O 2 reaction kinetics and parasitic reactions despite their theoretically high specific energy. Profound understanding of the cathode properties and the battery performance is rather critical in developing rational-designed electrocatalysts. In this study, a Co-N x /Co (111) decorated N-doped hierarchical carbon framework (Co-N x /Co@NHCF) is proposed as an efficient cathode in LOBs. Spectroscopic analysis coupled with experimental results suggests that the Co-N x /Co (111) catalytic center can significantly reduce the battery overpotential, and meanwhile, the hierarchical carbon framework ensures rapid mass transportation and provides sufficient space to accommodate Li 2 O 2 deposition. Density functional theory calculations reveal that the incorporated Co (111) facet can effectively regulate the electronic distribution of N-carbon, optimize the adsorption of desirable intermediates, and eventually facilitate oxygen reduction reaction/oxygen evolution reaction kinetics. As expected, the Co-N x /Co@NHCF catalyzed LOBs deliver a high discharge/charge capacity of 6.15/ 6.22 mAh cm −2 with a columbic efficiency of 98.9%, along with a high rate cycling of 700 h at 0.3 mA cm −2 . This work provides valuable instruction for the rational design of efficient catalysts for high-performance LOBs via optimization of the crystal structure and the adsorption of intermediates.
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CORROSION SCIENCE
·
2019
·
IF 6.355
Mingjun Cui,Siming Ren,Jibin Pu,Yonggang Wang,Haichao Zhao,Liping Wang
In this research, soluble poly(o-phenylenediamine) nanoparticles were synthesized to noncovalently functionalize the graphene nanosheets via π-π interactions, and the corresponding protective performance of epoxy composite coatings was also investigated. Results showed that the impedance modulus of the composite coatings incorporated with 0.5–1.0% G-Popd was about 10 10 Ω cm 2 after 60 days of immersion. Furthermore, the corrosion of substrate was still retarded even if there is an artificial scratch to the composite coatings. The superior protective performance of the composite coating derived from the synergistic action in the barrier property of graphene nanosheets and metal surface passivation by Popd nanoparticles.
研究领域:
材料科学
·
腐蚀与防护
·
纳米技术
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JOURNAL OF ANALYTICAL AND APPLIED PYROLYSIS
·
2024
·
IF 5.8
Xian Huang,Shangshu Peng,Shengshang Lu,Xinhai Wang,Yang Wu,Linxi Dai,Bo Chen,Quan Xie,Yunjun Ruan
Considerable attention has been devoted to creating porous carbons with exceptional surface area and porosity from biomass waste for energy storage devices. Herein, we employed a straightforward high-temperature carbonization and KOH activation method to synthesize nitrogen (N) and oxygen (O) co-doped porous activated carbons derived from luffa vines (LVACs). The impact of varying KOH concentrations on the morphology, structure, and electrochemical properties of LVACs was thoroughly investigated. The optimal mass ratio of KOH to LVACs at 1:6 achieved the maximum specific surface area of 3369 m 2 g −1 . At a current density of 1 A g −1 , the LASC-6 electrode exhibits an impressive specific capacitance of 348.5 F g −1 . It also demonstrates exceptional rate performance, retaining 70.6 % of its capacitance at a current density of 20 A g −1 . The electrode possesses robust cycling stability, retaining 90 % of the initial capacitance after 5000 cycles. We assessed the practicality of LVAC-6 by constructing symmetric supercapacitors (SSCs) using KOH and [BMIM]BF 4 electrolytes. The KOH and [BMIM]BF 4 SSCs achieved specific capacitances of 86.75 and 50.31 F g −1 , respectively, at a current density of 0.25 A g −1 . Moreover, the [BMIM]BF 4 SSC exhibited an impressive energy density of 51.05 Wh kg −1 at a power density of 346.15 W kg −1 . Therefore, we propose a simple and cost-effective strategy to produce porous carbon materials with excellent electrochemical performance from discarded biomass waste, facilitating the preparation of environmentally friendly electrode materials for high-performance supercapacitors.
研究领域:
材料科学
·
能源存储
·
环境科学
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FEBS LETTERS
·
2016
·Vol. 590
·期 16
·2619-2628
·
IF 3.519
Yu-Ying Zhang,Rui-Xue Xu,Shuai Gao,Ai-Xia Cheng
Oroxylin A and hispidulin, compounds which are abundant in both Scutellaria and liverwort species, are important lead compounds for the treatment of ischemic cerebrovascular disease. Their enzymatic synthesis requires an O -methyltransferase able to interact with the related flavonoid's 6-OH group, but such an enzyme has yet to be identified in plants. Here, the gene encoding an O -methyltransferase (designated PaF6OMT) was isolated from the liverwort species Plagiochasma appendiculatum . A test of alternative substrates revealed that its strongest preferences were baicalein and scutellarein, which were converted into, respectively, oroxylin A and hispidulin. Allowed a sufficient reaction time, the conversion rate of these two substrates was, respectively, 90% and 100%. PaF6OMT offers an enzymatic route to the synthesis of oroxylin A and hispidulin.
研究领域:
植物学
·
生物化学
·
药理学
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RSC Advances
·
2021
·Vol. 11
·期 49
·30725-30733
·
IF 3.361
Sen-Ju Ma,Hai-Bo Li,Ting Li,Zhen-Zhen Su,Zhen-Zhong Wang,Xin-Sheng Yao,Wei Xiao,Yang Yu
Phytochemical investigations on the dry leaves of Illicium dunnianum have led to the isolation of 24 lignans. Illiciumlignans G–K (1–5) were five undescribed benzofuran lignans, illiciumlignan L (6) was one undescribed ditetrahydrofuran lignan, illiciumlignans M–O (7–9) were three new sesquilignans, and compounds 10, 12, 13, 15, and 18–21 were firstly isolated from the genus Illicium. Their structures were elucidated by detailed spectroscopic analyses (UV, IR, HR-ESI-MS, and NMR) and CD experiments. All isolates were evaluated by measuring their inhibitory effects on PGE2, and NO production in LPS-stimulated RAW 264.7 macrophages.
研究领域:
植物化学
·
药理学
·
药物化学
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JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
·
2019
·
IF 3.571
Linhui Qin,Jianping Wang,RongRong Zhao,Xiao Zhang,Yingwu Mei
Ginsenoside-Rb1 (Rb1), a major active component of ginseng, has many benefits for cardiovascular disease and diabetes mellitus (DM), but the effect and mechanism on diabetic cardiomyopathy are not clear. In the present study, we found that Rb1-feeding significantly improved cardiac dysfunction and abnormal cardiomyocytes calcium signaling caused by diabetes. This improved calcium signaling was because Rb1 reduced Ca2+ leakage caused by overactivated ryanodine receptor 2 (RyR2) and increased Ca2+ uptake by sarcoplasmic reticulum Ca2+-ATPase 2a (SERCA 2a). Furthermore, we found that Rb1 not only enhanced energy metabolism like metformin and eliminated O-GlcNAcylation of calcium handling proteins to regulate calcium signaling but also directly inhibited RyR2 activity to regulate calcium signaling. The present study indicated that as a health supplement or drug, Rb1 was a relatively effective auxiliary therapeutic substance for diabetic cardiomyopathy.
研究领域:
药理学
·
心脏病学
·
糖尿病
·
分子生物学
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BIORESOURCE TECHNOLOGY
·
2026
·
IF 8.2
Weiwei Meng,Mengjian Gao,Lulu Li,Liming Liu,Xiaomin Li,Wanqing Wei,Jing Wu
Osteoarthritis remains a global health problem and chondroitin sulfate C (CSC) is effective to treat arthritis. The biosynthesis of CSC offers a sustainable and promising alternative to conventional extraction from animal tissues. However, the scarcity of chondroitin-6-O-sulfotransferases and their low catalytic performance have severely hindered the large-scale biosynthesis of CSC. To overcome these limitations, a novel chondroitin-6-O-sulfotransferase from Rattus norvegicus ( Rn CHST3) was identified via gene fishing, which demonstrates regioselectivity in transferring a sulfate group from 3′-phosphoadenosine-5′-phosphosulfate (PAPS) to the 6-position of chondroitin. Subsequent optimization of expression conditions and truncation of the N -terminal region enhanced the sulfation rate from 4.6% to 11.5%. For the first time, the regioselective mechanism of Rn CHST3 was elucidated through molecular dynamics (MD) simulations and site-directed mutagenesis. A mechanism-guided rational design led to the development of mutant M5, which increased the sulfation rate to 46.2%. Furthermore, a novel “physical sieve”-guided PROSS design was developed to improve kinetic thermostability, resulting in mutant M7. This variant exhibited an extended half-life from 9.4 h to 12.3 h and achieved a sulfation rate to 74.5%. Finally, a whole-cell catalytic system was constructed for CSC production, reaching a sulfation rate of 86.4% and a titer of 12.9 g·L −1 -the highest level reported to date. This study lays a solid foundation for the industrial biosynthesis of CSC.
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ELECTROCHIMICA ACTA
·
2012
·
IF 3.832
Shaohua Zheng,Ying Huang,Guonan Chen
In this paper, a sensitive graphite/poly(methyl methacrylate) (PMMA) composite electrode was firstly applied to the determination of o-sec -butylphenol ( os BP). This polymer carbon paste electrode (CPE) effectively improved the soft surface of traditional CPE, and enhanced the sensitivity and reproducibility. Factors influencing detection processes were optimized and kinetic parameters were calculated. Under the optimal conditions, the amperometric current density was linear with the concentration of os BP in the range from 2.50 × 10 −7 to 3.55 × 10 −5 mol L −1 and the detection limit was 3.48 × 10 −8 mol L −1 . The proposed method was successfully used to determine os BP in greengrocery samples and satisfactory results were obtained.
研究领域:
电化学
·
分析化学
·
环境监测
·
材料科学
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