Foods
·
2023
·Vol. 12
·期 24
·4425
·
IF 5.2
Xiaosan Zhang,Guangrong Huang,Hua Liu,Wenwei Chen,Jing Zhao,Zhenbao Jia,Fei Tao
Inhibiting α-amylase can lower postprandial blood glucose levels and delay glucose absorption, offering an effective approach for the development of antidiabetic diets. In this study, an active constituent with inhibitory activity against α-amylase was isolated and purified by bioassay-guided fractionation fromCarya cathayensisSarg. peel (CCSP). The active constituent was identified by NMR and Q-Exactive Orbitrap Mass Spectrometry as 5-O-p-coumaroylquinic acid (5-CQA). 5-CQA possessed strong inhibitory activity against α-amylase, with an IC50 value of 69.39 µM. In addition, the results of the kinetic study indicated that 5-CQA was a potent, reversible, noncompetitive inhibitor against α-amylase. The findings indicate that 5-CQA derived from CCSP has potential as a novel inhibitor against α-amylase, which can help mitigate postprandial blood sugar spikes, making it suitable for inclusion in antidiabetic diets.Keywords:Carya cathayensisSarg. Peel;postprandial hyperglycemia;5-O-p-coumaroylquinic acid;α-amylase inhibitor
研究领域:
植物化学
·
代谢病学
·
食品科学
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DOI
PubMed
高影响因子
E-POLYMERS
·
2022
·Vol. 22
·期 1
·973-985
·
IF 3.074
Hong Yin,Yao Shen,Zhirong Chen,Shenfeng Yuan,Xiaofeng Chen,Shihui Wang,Yanyu Jia,Jie Jiang,Jinbo Jia,Hangjun Deng
The substitutions of the chlorine atoms in p -dichlorobenzene (DCB) or the chlorine end-groups of polyphenylene sulfide (PPS) by sodium N -methyl-4-aminobutyrate (SMAB) are important reactions in the polymerization of PPS. The reaction process of DCB with SMAB was studied under conditions similar to the polymerization of PPS. The molecular structures of the products were analyzed through high-performance liquid chromatography, liquid chromatography-mass spectroscopy, gas chromatography-mass spectrometry, and other methods. Several pairs of para - and meta -isomer products were found, which indicates the coexistence of both nucleophilic addition–elimination (S N2 Ar) mechanism and aryne intermediate mechanism. Based on mechanism analysis, the networks of reactions of DCB with SMAB were proposed and the effects of the ratio of SMAB to DCB, water content, and temperature on the reaction process were studied.
研究领域:
材料科学
·
化学工程
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DOI
高影响因子
ACS Applied Materials & Interfaces
·
2021
·
IF 9.229
Lihui Liu,Ruimin Dong,Danqing Ye,Yao Lu,Pengfei Xia,Lingling Deng,Yu Duan,Kun Cao,Shufen Chen
Graphene is a promising flexible transparent electrode, and significant progress in graphene-based optoelectronic devices has been accomplished by reducing the sheet resistance and tuning the work function. Herein, phosphomolybdic acid (PMA) is proposed as a novel p-type chemical dopant for graphene, and the optical and electrical properties of graphene are investigated systematically. As a result, the monolayer graphene electrode with lower sheet resistance and work function are obtained while maintaining a high transmittance. The Raman spectrum proves the p-type doping effect of PMA on graphene, and the X-ray photoelectron spectroscopy results reveal the mechanism, which is that the electrons transfer from graphene to PMA through the Mo–O–C bond. Furthermore, using the PMA-doped graphene anode, organic and perovskite light-emitting diodes obtained the maximum efficiencies of 129.3 and 15.6 cd/A with an increase of 50.8 and 36.8% compared with the pristine counterparts, respectively. This work confirms that PMA is a potential p-type chemical dopant to achieve an ideal graphene electrode and demonstrates the feasibility of PMA-doped graphene in the practical application of next-generation displays and solid-state lighting.
研究领域:
材料科学
·
电子工程
·
光学
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DOI
高影响因子
MATERIALS SCIENCE IN SEMICONDUCTOR PROCESSING
·
2019
·
IF 2.722
Zhuangzhi Wu,Min Ouyang,Dezhi Wang
As a typical n-type semiconductor, MoSe 2 is limited in the application of photoelectrocatalytic hydrogen evolution due to the rapid recombination of photo-generated electron-hole pairs. To solve this problem, in this work, a p-type WS 2 is selected to design a WS 2 /MoSe 2 hybrid semiconductor catalyst with a p-n heterojunction . The obtained samples were characterized by XRD , Raman, SEM, TEM, UV and XPS . Besides, the photoelectrocatalytic performances for hydrogen production were also evaluated. It was found that the WS 2 /MoSe 2 hybrid catalyst with a loading of 20% WS 2 (20W-M) showed the best photocatalytic performance with a photocurrent density of 35 μA cm -2 at -0.6 V (vs SCE), much larger than those of single MoSe 2 (20 μA cm -2 ) and WS 2 (3.5 μA cm -2 ). And the improved performances should be ascribed to the construction of p-n heterojunction , which leads to the change of photoelectron-hole transport mode, accelerates the separation speed of carriers and prolongs the carrier lifetime. This work demonstrates the promoting effect of WS 2 as a cocatalyst and this strategy can be extended to other semiconductors.
研究领域:
材料科学
·
能源科学
·
催化化学
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DOI
高影响因子
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
·
2016
·
IF 2.822
Lingling Xi,Danwei Zhang,Fengli Wang,Zhongping Huang,Ting Ni
An excellent p -aminobenzene sulfonic acid ( p -ABSA) monolayer film was fabricated on glassy carbon electrode (GCE) by situ electrochemical oxidation . Then a novel kind of homogeneous quaternary amine-functionalized carbon nanotube (q-CNT) film was adsorbed onto p -ABSA/GCE through electrostatic interaction to produce q-CNT/ p -ABSA/GCE. Finally an electropolymerized poly( p -ABSA) film was formed on q-CNT/ p -ABSA/GCE. The electrostatic layer-by-layer assembly process of the modified electrode poly( p -ABSA)/q-CNT/ p -ABSA/GCE was well characterized by scanning electron microscopy (SEM), cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS) techniques. The modified electrode exhibited excellent electrocatalytic activity toward ascorbic acid (AA) oxidation at a low potential of + 0.02 V in pH 7.0 PBS. Amperometric experiments were performed for the sensitive determination of AA. Linear responses in two concentration ranges of 0.002–0.06 and 0.1–3.20 mM were obtained with the detection limit of 0.5 μM (S/N = 3). The electrostatic interaction of the positively charged q-CNTs with the monolayer p -ABSA film and the poly( p -ABSA) film promoted to form a stable poly( p -ABSA)/q-CNT/ p -ABSA composite film on GCE. So the poly( p -ABSA)/q-CNT/ p -ABSA/GCE showed good reproducibility and stability, and was successfully employed for the determination of AA in vitamin C tablet and human urine real samples with satisfactory results.
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产品关联
DOI
高影响因子
CHINESE JOURNAL OF CHEMICAL PHYSICS
·
2020
·Vol. 33
·期 4
·477-484
·
IF 1.067
Qi Ling-li,Zhong Chun-yan,Deng Zan-hong,Dai Tian-tian,Chang Jun-qing,Wang Shi-mao,Fang Xiao-dong,Meng Gang
In this work, p-type Co 3 O 4 decorated n-type ZnO (Co 3 O 4 /ZnO) nanocomposite was designed with the assistance of bacterial cellulose template. Phase composition, morphology and element distribution were investigated by XRD, SEM, HRTEM, EDS mapping and XPS. Volatile organic compounds (VOCs) sensing measurements indicated a noticeable improvement of response and decrease of working temperature for Co 3 O 4 /ZnO sensor, in comparison with pure ZnO, i.e ., the response towards 100 ppm acetone was 63.7 (at a low working temperature of 180 °C), which was 26 times higher than pure ZnO (response of 2.3 at 240 °C). Excellent VOCs response characteristics could be ascribed to increased surface oxygen vacancy concentration (revealed by defect characterizations), catalytic activity of Co 3 O 4 and the special p-n heterojunction structure, and bacterial cellulose provides a facile template for designing diverse functional heterojunctions for VOCs detection and other applications.
研究领域:
材料科学
·
环境科学
·
传感器技术
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DOI
高影响因子
Russian Journal of Physical Chemistry A
·
2022
·Vol. 96
·期 11
·2490-2496
·
IF 0.791
Khan Misbah Ullah,Ullah Hayat,Honey Shehla,Gul Zarif,Ullah Shaheed,Ullah Bakhtar,Manan Abdul,Ullah Munzer,Ali Shad
Abstract Noble metal bimetallic nanostructures, such as Ag and Au, are used in a variety of fields including nanoscience, catalysis, electronics and nanotechnology because of high stability and adsorption rate etc. However controlled synthesis of bimetallic nanostructures is challenging. Therefore, the current study emphasizes on two step controlled synthesis of Au/Ag nanostructures with tunable sizes for catalytic purposes. Using electrochemical deposition (EC) technique, the fabrication of Au/Ag nanostructures were achieved in two stages, through galvanic reaction. The catalytic capabilities of an Au/Ag nanostructure and Ag flower-like structure were examined through reduction of p -nitrophenol in the presence of sodium borohydride (NaBH 4 ). The catalytic investigation was measured in temperatures rage of 25 to 45°C at constant time. The study shows that catalytic activity of Au/Ag nanostructure is higher than that of Ag flower-like structure in the reduction of p -nitrophenol.
研究领域:
纳米科学
·
催化化学
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DOI
高影响因子
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
·
2021
·
IF 5.279
Jia-Xu Nan,Jing-Fang Yang,Hong-Yan Lin,Yao-Chao Yan,Shao-Meng Zhou,Xue-Fang Wei,Qiong Chen,Wen-Chao Yang,Ren-Yu Qu,Guang-Fu Yang
Exploring novel p-hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27, HPPD) inhibitors has become one of the most promising research directions in herbicide innovation. On the basis of our tremendous interest in exploiting more powerful HPPD inhibitors, we designed a family of benzyl-containing triketone-aminopyridines via a structure-based drug design (SBDD) strategy and then synthesized them. Among these prepared derivatives, the best active 3-hydroxy-2-(3,5,6-trichloro-4-((4-isopropylbenzyl)amino)picolinoyl)cyclohex-2-en-1-one (23, IC50 = 0.047 μM) exhibited a 5.8-fold enhancement in inhibiting Arabidopsis thaliana (At) HPPD activity over that of commercial mesotrione (IC50 = 0.273 μM). The predicted docking models and calculated energy contributions of the key residues for small molecules suggested that an additional π–π stacking interaction with Phe-392 and hydrophobic contacts with Met-335 and Pro-384 were detected in AtHPPD upon the binding of the best active compound 23 compared with that of the reference mesotrione. Such a molecular mechanism and the resulting binding affinities coincide with the proposed design scheme and experimental values. It is noteworthy that inhibitors 16 (3-hydroxy-2-(3,5,6-trichloro-4-((4-chlorobenzyl)amino)picolinoyl)cyclohex-2-en-1-one), 22 (3-hydroxy-2-(3,5,6-trichloro-4-((4-methylbenzyl)amino)picolinoyl)cyclohex-2-en-1-one), and 23 displayed excellent greenhouse herbicidal effects at 150 g of active ingredient (ai)/ha after postemergence treatment. Furthermore, compound 16 showed superior weed-controlling efficacy against Setaria viridis (S. viridis) versus that of the positive control mesotrione at multiple test dosages (120, 60, and 30 g ai/ha). These findings imply that compound 16, as a novel lead of HPPD inhibitors, possesses great potential for application in specifically combating the malignant weed S. viridis.
研究领域:
植物学
·
药理学
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DOI
PubMed
高影响因子
Nano Energy
·
2017
·
IF 12.343
Xiaolin Lv,Kaiqi Nie,Huiwen Lan,Xin Li,Youyong Li,Xuhui Sun,Jun Zhong,Shuit-Tong Lee
Hematite is a promising photocatalyst for solar water splitting while its performance has been severely limited by various factors. Recently surface Fe 2 TiO 5 layer was widely reported to enhance the performance of hematite with a favorable band position to facilitate hole transport. Here we further show that the Fe 2 TiO 5 -incorporation in bulk hematite can also improve the performance with faster charge separation. Moreover, it can be well coupled with surface P-modification to simultaneously improve charge separation and hole transfer with a synergetic effect. The Ti and P co-modified hematite shows a significantly enhanced photocurrent of 2.37 mA/cm 2 at 1.23 V vs. RHE when compared to the pristine value of 0.85 mA/cm 2 . After coupling with Co-Pi catalysts, the hematite sample can even achieve a stable, high photocurrent of 2.90 mA/cm 2 at 1.23 V vs. RHE. The design of Ti and P co-modified hematite hollow nanostructures can be used as a promising candidate for solar water splitting applications. The discrete Fe 2 TiO 5 -incorporation also provides a good insight on the mechanism to understand other Ti-based treatments of hematite.
研究领域:
材料科学
·
光催化
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DOI
高影响因子
CHEMISTRY-A EUROPEAN JOURNAL
·
2020
·Vol. 26
·期 17
·3870-3876
·
IF 4.857
Xiaoshan Wang,Yao Liu,Jie Dai,Qian Chen,Xiao Huang,Wei Huang
Graphical By taking advantage of the crystal phase dependent electronic property of SnSe x based materials, SnSe( x %)/SnSe 2 (100− x %) p–n heterostructures were synthesized via a facile one-step colloidal method, and the SnSe(50 %)/SnSe 2 (50 %) based sensor exhibited much improved sensing performance due to the formation of p–n hetero-junctions. The formation of semiconductor heterostructures is an effective approach to achieve high performance in electrical gas sensing. However, such heterostructures are usually prepared via multi-step procedures. In this contribution, by taking advantage of the crystal phase-dependent electronic property of SnSe x based materials, we report a one-step colloid method for the preparation of SnSe( x %)/SnSe 2 (100− x %) p–n heterostructures, with x ≈30, 50, and 70. The obtained materials with solution processability were successfully fabricated into NO 2 sensors. Among them, the SnSe(50 %)/SnSe 2 (50 %) based sensor with an active layer thickness of 2 μm exhibited the highest sensitivity to NO 2 (30 % at 0.1 ppm) with a limit of detection (LOD) down to 69 ppb at room temperature (25 °C). This was mainly attributed to the formation of p–n junctions that allowed for gas-induced modification of the junction barriers. Under 405 nm laser illumination, the sensor performance was further enhanced, exhibiting a 3.5 times increased response toward 0.1 ppm NO 2 , along with a recovery time of 4.6 min.
研究领域:
材料科学
·
化学传感器
·
纳米技术
✓ 已验证
DOI
高影响因子
RUSSIAN JOURNAL OF GENERAL CHEMISTRY
·
2023
·Vol. 93
·期 9
·2371-2377
·
IF 0.9
Wen Min,Fu Xue,Li Ting,Ouyang Fenfen,Zha Guodong,Zhu Liqing
Abstract The misuse of antibiotics drives clinical antimicrobial resistance, with detrimental impacts for human health. Therefore, some new antibacterial materials should be developed to address the overuse of clinical antimicrobials. As a new nanomaterial with good biocompatibility and low toxicity, carbon quantum dots (CQDs) are excellent candidates as novel antimicrobial agents. In this study, we prepared blue-emitting phosphorus-doped carbon quantum dots (P-CQDs) with an optimal excitation wavelength of 370 nm and an optimal emission wavelength of 445 nm by a simple and environmentally-friendly one-step hydrothermal method using keratin as the carbon source. We found that P-CQDs exhibited inhibitory effects on microorganisms, with the minimal inhibitory concentration (MIC) values of 0.19 mg/mL against Gram-positive bacteria ( S. aureus ) and 0.31 mg/mL against Gram-negative bacteria ( E. coli ). The experimental results implied these stable fluorescence properties of P-CQDs possess good antibacterial activity. Thus, these findings indicate the P-CQDs based on biosynthesized keratin could potentially be used as an excellent antibacterial agent.
研究领域:
材料科学
·
纳米技术
·
生物医学工程
·
微生物学
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DOI
高影响因子
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
·
2016
·Vol. 23
·期 8
·7627-7638
·
IF 2.76
Zhu Nengwu,Cao Yanlan,Shi Chaohong,Wu Pingxiao,Ma Haiqin
Recovery of gold from aqueous solution using simple and economical methodologies is highly desirable. In this work, recovery of gold as gold nanoparticles (AuNPs) by Shewanella haliotis with sodium lactate as electron donor was explored. The results showed that the process was affected by the concentration of biomass, sodium lactate, and initial gold ions as well as pH value. Specifically, the presence of sodium lactate determines the formation of nanoparticles, biomass, and AuCl 4
− concentration mainly affected the size and dispersity of the products, reaction pH greatly affected the recovery efficiency, and morphology of the products in the recovery process. Under appropriate conditions (5.25 g/L biomass, 40 mM sodium lactate, 0.5 mM AuCl 4
− , and pH of 5), the recovery efficiency was almost 99 %, and the recovered AuNPs were mainly spherical with size range of 10–30 nm (~85 %). Meanwhile, Fourier transforms infrared spectroscopy and X-ray photoelectron spectroscopy demonstrated that carboxyl and amine groups might play an important role in the process. In addition, the catalytic activity of the AuNPs recovered under various conditions was testified by analyzing the reduction rate of p -nitrophenol by borohydride. The biorecovered AuNPs exhibited interesting size and shape-dependent catalytic activity, of which the spherical particle with smaller size showed the highest catalytic reduction activity with rate constant of 0.665 min −1 .
研究领域:
环境科学
·
纳米技术
·
生物冶金
·
微生物生物技术
·
催化
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DOI
高影响因子
危险品化学品经营许可证（带存储）