MATERIALS LETTERS
·
2012
·
IF 2.307
Hanning Duan,Xianfeng Zheng,Songliu Yuan,Yu Li,Zhaoming Tian,Zhao Deng,Baolian Su
Organic solution-phase reaction under oxygen atmosphere for synthesis of single crystalline and uniform sub-3 nm NiO nanoparticles has been developed. Larger NiO nanoparticles with diameter about 26 nm can be also prepared by seed-mediated growth method. Optical property of the NiO nanoparticles was conducted by means of UV–vis spectrum, exhibiting obviously blue shift compared with the bulk counterpart due to the quantum confinement effect . The photocatalytic activity in degradation of rhodamine B was also investigated. The results showed that the sub-3 nm NiO nanoparticles exhibit much higher activity for UV-photodegradation than the as-synthesized larger NiO particles and commercial 30 nm nanopowder .
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高影响因子
ACS Applied Materials & Interfaces
·
2023
·
IF 9.5
Xiaoyi Li,Yongjian Zhou,Jiawen Tang,Siliang Zhao,Jingyong Zhang,Xiao Huang,Bingbing Tian
NASICON-type Li1.3Al0.3Ti1.7(PO4)3 (LATP) has attracted a lot of attention because of its high ionic conductivity and stability to air and moisture. However, the size effect of LATP primary particles on ionic conductivity is ignored. In this study, different sizes of LATP particles are prepared to investigate the morphology, relative density, and ionic conductivity of the LATP solid electrolyte. The influences of particle size and sintering temperature on the microstructure, phase composition, and electrical properties of LATP ceramics were systematically studied. The medium-sized LATP particle (2 μm) presents a great microstructure with a high relative density of over 97%, the highest ionic conductivity of 6.7 × 10–4 S cm–1, and an activation energy of 0.418 eV. The Li–Li symmetric cells and Li–LFP batteries delivering good electrochemical performance were fabricated with highly conductive LATP ceramics. These results make significant strides in elucidating the relationship between the particle sizes of LATP and its electrochemical performance.
研究领域:
材料科学
·
固体离子学
·
储能
·
陶瓷材料
·
电化学
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ACTA MATERIALIA
·
2024
·
IF 8.3
Qingjie Wang,Yongqiang Qiao,Kaiyue Zhao,Peixian Zhang,Huan Zhao,Juan Guo,Xinwei Shi,Erjun Liang,Qilong Gao
Zero thermal expansion (ZTE) materials can solve problems such as device failure and cracking caused by mismatched coefficient of thermal expansion . However, ZTE material is rare in nature. NaZr 2 (PO 4 ) 3 is a framework compound with near-zero thermal expansion due to coupled rotations of rigid ZrO 6 and PO 4 polyhedra in the structure, and several studies have been devoted to obtaining more ZTE compounds by chemical substitution of Na or Zr. Inspired by the AAV concept we proposed, in this work, the PO 4 tetrahedra with a small volume has been replaced by the large volume MoO 4 tetrahedra in K x Mn x In 2- x (MoO 4 ) 3 ( x = 0.4, 0.6, 0.8, and 1.0) compounds to provide more space for the coupling rotation of the polyhedron, and reduce the coefficient of thermal expansion. On the other hand, the flexibility of the framework structure has been modulated by the content of K + to achieve new ZTE materials, and the effects of K + content on crystal structure and thermal expansion have been analyzed in detail by combining variable temperature XRD and Raman. These findings not only provide more ZTE materials, but also suggest a promising design method for ZTE materials.
研究领域:
材料科学
·
固体化学
·
热功能材料
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Materials Reports: Energy
·
2022
·
IF 0
Zhanyou Xu,Yi Xie,Ying Wang
Electrochemical CO 2 reduction reaction (CO 2 RR) exhibits remarkable potential in producing valuable chemicals with renewable energy. Operating CO 2 RR in acidic media is beneficial to solve the issue of low carbon utilization brought by (bi)carbonate formation at the cathode. Suppressing the competing hydrogen evolution reaction and achieving stable CO 2 RR performance remains challenging. Herein, we constructed a 3-dimensional Cu (3D-Cu) gas diffusion electrode (GDE) to achieve efficient C 2 H 4 production with a partial current density ( j C2H4 ) of over 470 mA cm −2 and a Faradaic efficiency (FE C2H4 ) of 40%. With pause electrolysis, the decay rate of the j C2H4 is only half that of the traditional constant electrolysis. The GDE after constant electrolysis was found to suffer from severe salt formation, leading to the decreased activity and poor stability.
研究领域:
电化学
·
材料科学
·
能源化学
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DOI
Chem & Bio Engineering
·
2026
·
IF 8.4
He Qin,Cheng Shuai,Yue Jianqing,Zong Shu,Li Congyu,Qi Xuerong,Liu Lipei,Zhang Zhidan,Sun Jun,Cheng Jian,Lu Xiaoyun,Jiang Huifeng
3 ′ -O-amino-deoxyribonucleoside
triphosphates (3 ′ -ONH 2 -dNTPs) are crucial reversible
terminators for template-independent
DNA synthesis. Owing to the structural complexity of purine bases,
here we propose a chemo-enzymatic process for the synthesis of purine-type
3 ′ -ONH 2 -dNTPs. First, the aminoalkoxyl group was
introduced into commercially available dA and dG via a chemical catalytic
process, affording yields of 24.9% and 27.3%, respectively. Subsequently,
to establish a green and scalable enzymatic cascade for phosphorylation
of the substrates, we engineered two key phosphorylation enzymes (Dm-dNK
and MrPPK2), improving the rate-limiting monophosphorylation of 3 ′ -ONH 2 -dG from 26% to 97.8% and achieving 59.9% conversion to the
corresponding triphosphate. Lastly, the produced nucleotides exhibit
performance equivalent to commercial counterparts in terminal deoxynucleotidyl
transferase (TdT)-mediated DNA synthesis, supporting the construction
of 120-nt strands with ∼99.7% stepwise accuracy. This work
establishes an efficient and generalizable catalytic platform for
producing modified dNTPs, advancing the practical application of enzymatic
DNA synthesis technologies.
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Nature Communications
·
2026
·
IF 18.1
Zhao Zihan,He Zhen,Gu Hongming,Zhou Andong,Wang Yibing,Liang Zhaoyi,Geng Jie,Xu Xuejiao,Wang Menghui,Li Chunyao,Fan Yuying,Cheng Hairong,Sun Lin,Mayo Kevin H.,Raz Avraham,Tai Guihua,Zhou Yifa
The mechanism of unconventional protein secretion remains an unresolved issue. Here, we describe an unconventional protein secretion pathway for galectin-3 that is mediated by phase separation and condensation. Using four lysosomal damage models, we observed a rapid, pronounced release of galectin-3 in large, non-exosomal particles. This secretion is driven by glycoprotein-induced galectin-3 phase separation and is independent of pyroptosis and secretory autophagy. During phase separation, the S-face of galectin-3 carbohydrate recognition domain binds glycoproteins that triggers galectin-3 N-terminal tail release and condensation. These condensates then recruit ALG-2 via the exposed N-terminal tail. ALG-2 directs the condensates to the endoplasmic reticulum–late endosome interface. After translocation into late endosomes, galectin-3 condensates are secreted into the extracellular milieu by SNARE-dependent vesicular transport. This mechanism of exporting phase-separated protein condensates may serve as a clean-up response to membrane damage.
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产品关联
DOI
PubMed
高影响因子
Science China-Chemistry
·
2026
·
IF 9.8
Dai Huan,Yang Mingyu,Yang Hongkun,Liu Haiquan,Ke Zunjian,He Dong,Xiao Xiangheng
Electrochemical nitrate reduction (NO 3 RR) represents an environmentally sound pathway for converting nitrate ions (NO
− 3
) to ammonia in wastewater. However, the mechanism governing NO
− 3
hydrogenation under altered liquid-phase conditions remains poorly understood. This study enhances the reactivity of CeO 2 toward nitrate hydrogenation by loading it with transition metals and further modifying the composition of alkali metal cations in the electrolyte. This approach regulates the continuity of both interfacial water and hydrogen-bond networks, facilitating NO
− 3
-proton coupling and thereby boosting NO 3 RR reactivity. Furthermore, the incorporation of diverse surfactants into the electrolyte confirms that alterations in the liquid-phase environment influence interfacial water distribution, ultimately improving NO 3 RR reactivity. This study deepens our understanding of interfacial water’s role in NO 3 RR, providing a theoretical basis for developing more efficient electrocatalysts.
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CELLULAR SIGNALLING
·
2026
·
IF 4.7
Guangyuan Li,Mingyu Peng,Mengxue Li,Ruoyu Hu,Chunxiao Gao,Yamin Xing,Ting Zhang,Jixuan Xu,Miaoran Fu,Wulong Liang,Pengya Feng,Hongqiao Zhang,Zisen Zhang,Pengyuan Zheng,Xiufeng Chu
Pyroptosis is a form of programmed cell death mediated by gasdermin proteins, with GSDMD and GSDME being the most extensively studied. Inflammatory caspases-1 or caspases-4/5/11 cleave GSDMD and release its pore-forming fragment GSDMD-NT, whereas the apoptotic caspase-3, cleaves GSDME and releases its pore-forming fragment GSDME-NT. In this study, we observed that caspase-3 is activated during GSDMD-mediated pyroptosis. Interestingly, downregulation of caspase-3 activity either through RNAi or caspase-3 inhibitor significantly increased cell death. Furthermore, we found that caspase-3 physically interacts with GSDMD-NT and cleaves it at a site distinct from those targeted by caspase-1 or caspases-4/5/11. This alternative cleavage generates a non-functional fragment of GSDMD-NT, thereby disrupting its integrity. Consequently, we demonstrate that caspase-3 activation serves as a negative feedback mechanism to regulate the intensity of GSDMD-NT-mediated pyroptosis.
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产品关联
DOI
PubMed
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2015
·
IF 2.999
Jian Liu,Xiulan Duan,Yang Zhang,Ziqing Li,Fapeng Yu,Huaidong Jiang
Rb 2 Ti 1.95 Yb 0.05 (PO 4 ) 3 crystals with langbeinite-type structure were grown by high-temperature solution method. The chemical composition and electronic structure were analyzed using inductive coupled plasma atomic emission spectroscopy (ICP-AES) and X-ray photoelectron spectroscopy (XPS). The deconvolution of Ti 2p 3/2 photoemission line reveals two peaks at 459.3 eV and 458.1 eV, indicating titanium existence in two valence states: Ti 4+ (459.3 eV) and Ti 3+ (458.1 eV). The reduced BE difference ΔBE (O 1s-Ti 2p 3/2 ) shows stronger ionicity of Ti–O bonds in Rb 2 Ti 1.95 Yb 0.05 (PO 4 ) 3 compared with RbTiOPO 4 . Additionally, UV absorption, specific heat, and second harmonic generation (SHG) efficiency were studied. The UV absorption edge of the Rb 2 Ti 1.95 Yb 0.05 (PO 4 ) 3 crystal was observed at 368 nm. The SHG intensity of Rb 2 Ti 1.95 Yb 0.05 (PO 4 ) 3 is 5–6 times greater than that of KDP crystal when the particle size is between 38 and 74 μm.
研究领域:
材料科学
·
物理学
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DOI
高影响因子
Materials Futures
·
2022
·Vol. 1
·期 4
·045201
·
IF 0
Kangqiao Cheng,Wei Xie,Shuo Zou,Huanpeng Bu,Jin-Ke Bao,Zengwei Zhu,Hanjie Guo,Chao Cao,Yongkang Luo
Rhodium-containing compounds offer a fertile playground to explore novel materials with superconductivity (SC) and other fantastic electronic correlation effects. A new ternary rhodium-antimonide La2Rh_{3+\delta}Sb4 (\delta\approx 1/8) has been synthesized by a Bi-flux method. It crystallizes in the orthorhombic Pr2Ir3Sb4-like structure, with the space group Pnma (No. 62). The crystalline structure appears as stacking the two-dimensional RhSb4- and RhSb5-polyhedra networks along b axis, and the La atoms embed in the cavities of these networks. Band structure calculations confirm it as a multi-band metal with a van-Hove singularity like feature at the Fermi level, whose density of states are mainly of Rh-4d and Sb-5p characters. The calculations also imply that the redundant Rh acts as charge dopant. SC is observed in this material with onset transition at T_c^\mathrm{on}\approx 0.8 K. Ultra-low temperature magnetic susceptibility and specific heat measurements suggest that it is an s-wave type-II superconductor. Our work may also imply that the broad Ln_2Tm_{3+\delta}Sb4 (Ln = rare earth, Tm = Rh, Ir) family may host new material bases where new superconductors, quantum magnetism and other electronic correlation effects could be found.
研究领域:
凝聚态物理学
·
材料科学
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DOI
JOURNAL OF ORGANIC CHEMISTRY
·
2017
·
IF 4.849
Jian Cheng,Jun Sun,Jiekuan Yan,Song Yang,Pengcheng Zheng,Zhichao Jin,Yonggui Robin Chi
The metal-free catalytic functionalization of aromatic sp2-carbons and benzylic sp3-carbons remains challenging. Here we report a carbene-catalyzed functionalization of the 3-methyl sp3-carbon attached to 2-formyl-indoles. The reaction proceeds through an NHC-bound o-quinodimethane as the key intermediate generated from 2-formyl-3-methylindoles under oxidative conditions. Reactive ketones are found to be effective substrates to produce substituted hydropyrano[3,4-b]indoles in good to excellent yields.
研究领域:
有机化学
·
合成化学
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DOI
高影响因子
Acta Pharmaceutica Sinica B
·
2020
·
IF 7.097
Meng Yuan,Xiaobing Chen,Yitang Sun,Li Jiang,Zhongni Xia,Kaixiong Ye,Hong Jiang,Bo Yang,Meidan Ying,Ji Cao,Qiaojun He
The membrane protein claudin-3 (CLDN3) is critical for the formation and maintenance of tight junction and its high expression has been implicated in dictating malignant progression in various cancers. However, the post-translational modification of CLDN3 and its biological function remains poorly understood. Here, we report that CLDN3 is positively correlated with ovarian cancer progression both in vitro and in vivo. Of interest, CLDN3 undergoes S -palmitoylation on three juxtamembrane cysteine residues, which contribute to the accurate plasma membrane localization and protein stability of CLDN3 . Moreover, the deprivation of S -palmitoylation in CLDN3 significantly abolishes its tumorigenic promotion effect in ovarian cancer cells. By utilizing the co-immunoprecipitation assay, we further identify ZDHHC12 as a CLDN3-targating palmitoyltransferase from 23 ZDHHC family proteins. Furthermore, the knockdown of ZDHHC12 also significantly inhibits CLDN3 accurate membrane localization, protein stability and ovarian cancer cells tumorigenesis . Thus, our work reveals S -palmitoylation as a novel regulatory mechanism that modulates CLDN3 function, which implies that targeting ZDHHC12-mediated CLDN3 S -palmitoylation might be a potential strategy for ovarian cancer therapy.
研究领域:
癌症生物学
·
细胞生物学
·
分子生物学
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DOI
PubMed
高影响因子
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