TALANTA
·
2019
·
IF 4.916
Zhenwei Yuan,Mingjun Xu,Tianze Wu,Xinyi Zhang,Yuanzhi Shen,Umeorah Ernest,Lijuan Gui,Fei Wang,Qing He,Haiyan Chen
As an over-expressed flavoprotein in several kinds of tumor cells, NAD(P)H: quinone oxidoreductase-1 (NQO1) is considered as a potent biomarker in early-stage cancer diagnosis. Developing a fast, selective and sensitive method of monitoring NQO1 on cellular level will greatly promote cancer diagnosis in clinical practice. In this paper, a fast NQO1 responsive fluorescence probe SYZ-30 containing quinone acid and 7-nitro-2,1,3-benzoxadiazole (NBD) fluorophore is constructed. The probe could selectively respond to NQO1 and rapidly emit strong fluorescence in vitro within only 5 min. Notably, the peak fluorescent intensities at 550 nm showed a linear relationship with NQO1 concentrations in the range of 3–30 ng/ml and limit of detection (LOD) was 0.0667 ng/ml. Furthermore, it was validated that the probe has good biocompatibility and could be applied for bio-imaging in NQO1 over-expressed cancer cells, together with its mitochondria targeting ability. Importantly, confocal fluorescence imaging confirmed the NQO1 detection ability on cellular level, which can be used for real-time detection of several cancer subtypes like adenocarcinoma. To conclude, the probe is rapidly responsive, highly sensitive and selective which will potentially become a practical tool for early cancer detection and diagnosis.
研究领域:
癌症生物学
·
生物化学
·
分子生物学
·
生物医学工程
✓ 已验证
DOI
PubMed
高影响因子
CERAMICS INTERNATIONAL
·
2022
·
IF 5.532
Xianzhe Zhang,Pengpeng Dai,Dawei Wen
Portable near-infrared (NIR) lighting source stimulates great efforts to exploit NIR phosphor-converted LEDs (pc-LEDs) that push the rapid development of broadband NIR-emitting phosphors. Although Cr 3+ -activated NIR phosphors designed by multisites occupation strategy show significant potential in emission bandwidth, poor spectral stability caused by different thermal quenching behaviors is a brake on practical application due to different local structure around Cr centers. One-site-based NIR phosphors seem to be an effective method to solve aforementioned problem. Herein, we report a type of new ultra-broadband one-site-based NIR-emitting phosphors NaSc 1-x P 2 O 7 :xCr 3+ (NSP:xCr 3+ ) with emission at 910 nm and full width at half maximum (FWHM) of up to ∼200 nm. Their FWHM value exceeds all one-site-based Cr 3+ -activated phosphors and some multiple-sites ones. Structural analysis and low-temperature spectra demonstrate that such impressive broadband NIR emission originates from Cr 3+ occupying at single octahedral Sc site. At 425 K, integrated emission intensity of NSP:0.04Cr 3+ phosphor maintains 53.8% of room temperature. A NIR pc-LED prototype is fabricated by using NSP:0.04Cr 3+ phosphor with a blue LED chip, and its multipurpose applications in non-destructive detection, night vision and analysis of foodstuff are demonstrated. These findings indicate that broadband NSP:0.04Cr 3+ NIR phosphor enabled by one-site occupation strategy has potential prospect for multipurpose NIR pc-LEDs applications.
研究领域:
材料科学
·
光电技术
·
光子学
·
固体物理
·
照明技术
✓ 已验证
DOI
高影响因子
Science China-Chemistry
·
2022
·Vol. 65
·期 3
·521-531
·
IF 10.138
Chen Zhida,Chen Wenda,Zheng Lirong,Huang Tao,Hu Jing,Lei Yaqi,Yuan Qi,Ren Xiangzhong,Li Yongliang,Zhang Lei,Huang Shaoluan,Ye Shenghua,Zhang Qianling,Ouyang Xiaoping,Sun Xueliang,Liu Jianhong
In this study, the morphological distribution of Ru on nitrogen-doped graphene (NG) could be rationally regulated via modulating the combination mode between Ru precursor and the zeolite imidazolate framework-8 (ZIF-8). The cation exchange and host-guest strategies respectively resulted in two different combination modes between Ru precursor and ZIF-8 anchored on graphene. Following pyrolysis of the above precursors, Ru single-atom sites (SASs) with and without Ru nanoparticles (NPs) were formed selectively on NG (denoted as Ru SASs+NPs/NG and Ru SASs/NG, respectively). Ru SASs+NPs/NG exhibited excellent hydrogen evolution reaction (HER) performance in alkaline solutions ( η 10 =12 mV, 12.57 A mg −1 Ru at 100 mV), which is much better than Ru SASs/NG. The experimental and theoretical study revealed that Ru SASs could adsorb hydrogen with optimal adsorption strength, while Ru NPs could lower the barrier of water molecule dissociation, and thus Ru SASs and Ru NPs could synergistically promote the catalytic performance of HER in alkaline solutions.
研究领域:
材料科学
·
催化化学
✓ 已验证
DOI
高影响因子
JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY
·
2023
·Vol. 332
·期 9
·3787-3798
·
IF 1.6
Liu Nana,Fang Ziyi,Xu Yunan,Xue Miao,Zhan Liyuan,Wang Binliang,Yuan Yijun
In response to the depletion of global uranium reserves and the radioactive contamination of wastewater, there is an urgent need to develop efficient, sustainable, and cost-effective uranium biosorbents. Herein, a green macroalga Rhizoclonium riparium was prepared for uranium (U(VI)) removal. The results showed that the maximum adsorption capacity of U(VI) was 80.96 mg g −1 (pH = 5, 298 K and 0.1 M NaNO 3 ). The kinetics, isotherms and thermodynamics analysis revealed that the adsorption process was chemisorption, homogeneous monolayer adsorption, endothermic and spontaneous. Through the mechanism characterization, it was proved the adsorbed of uranium on R. riparium was mainly controlled by the complexation between U(VI) and –OH, –COOH, –NH 2 . Besides, the R. riparium possess high selectivity towards uranium and good recycling performance. This work highlights new opportunities for biosorbents to be obtained directly from nature and used to remove radioactive contamination.
研究领域:
环境科学
·
生物技术
✓ 已验证
DOI
高影响因子
Nano Research
·
2021
·Vol. 15
·期 4
·3195-3203
·
IF 8.897
Wang Yan,Gao Hexiang,Wu Wenjia,Zhou Zhuofan,Yang Zhiwei,Wang Jingtao,Zou Yecheng
Porous laminar membranes hold great promise to realize ultrafast ion transfer if efficient and stable transfer channels are constructed in vertical direction. Here, metal-organic framework (MOF) nanosheets bearing imidazole molecules in the pores were designed as building blocks to assemble free-standing MOF laminar membrane. Then, Nafion chains were threaded into the pores induced by electrostatic attraction from imidazole molecules by slowly filtering dilute Nafion solution. We demonstrate that the threaded Nafion chains lock adjacent MOF nanosheets, affording highly enhanced structural stability to the resultant laminar membrane with almost no water swelling. Significantly, abundant acid-base pairs are formed in the pores along Nafion chains, working as efficient, continuous conduction pathways in vertical direction. Proton conductivities as high as 110 and 46 mS·cm −1 are obtained by this membrane under 100% and 40% relative humidity (RH), respectively, which are two orders of magnitude higher than that of pristine MOF membrane. The conductivity under low humidity (40% RH) is even over 2 times higher than that of commercial Nafion membrane, generating the maximum power density of 1,100 mW·cm −2 in hydrogen fuel cell (vs. 291 mW·cm −2 of Nafion membrane). Besides, the influence of water state on proton transfer in confined space is investigated in detail.
研究领域:
材料科学
·
能源科学
✓ 已验证
DOI
高影响因子
ANNALS OF BIOMEDICAL ENGINEERING
·
2020
·Vol. 48
·期 5
·1511-1523
·
IF 3.324
Ding Yilei,Zhao An-sha,Liu Tianmei,Wang Ya-nan,Gao Yuan,Li Jing-an,Yang Ping
In this contribution, an injectable hydrogel was developed with chitosan, gelatin, β-glycerphosphate and Arg-Gly-Asp (RGD) peptide: this hydrogel is liquid in room temperature and rapidly gels at 37 °C; RGD peptide promises better growth microenvironment for various cells, especially endothelial cells (EC), smooth muscle cells (SMC) and mesenchymal stem cells (MSC). Both stromal cell-derived factor-1 (SDF-1) nanoparticle and vascular endothelial growth factor (VEGF) nanoparticles were loaded in the injectable hydrogel to simulate the natural nanoparticles in the extracellular matrix (ECM) to promote angiogenesis. In vitro EC/SMC and MSC/SMC co-culture experiment indicated that the nanocomposite hydrogel accelerated constructing embryonic form of blood vessels, and chick embryo chorioallantoic membrane model demonstrated its ability of improving cells migration and blood vessel regeneration. We injected this nanocomposite hydrogel into rat myocardial infarction (MI) model and the results indicated that the rats heart function recovered better compared control group. We hope this injectable nanocomposite hydrogel may possess wider application in tissue engineering.
研究领域:
生物材料学
·
再生医学
·
心血管研究
·
组织工程
✓ 已验证
DOI
PubMed
高影响因子
Journal of Applied Spectroscopy
·
2022
·Vol. 89
·期 5
·992-1001
·
IF 0.816
Chen Y.,Cao J.,Wie H.,Wu Zh.,Wei Y.
Flexible surface-enhanced Raman spectroscopy (SERS) substrates were produced by in situ chemical reduction of Ag + on poly(vinyl alcohol)/chitosan (PVA/CS) nanofibers. PVA/CS nanofibers (which have a large number of amino and hydroxyl functional groups) were prepared by electrospinning, which can provide more sites for adsorbing Ag + than pure PVA. The Ag nanoparticles were evenly distributed on the PVA/CS nanofibers. The SERS substrate also exhibited excellent water stability, sensitivity, and uniformity. The detection limit of probe molecule rhodamine 6G was 10 −7 M and the relative standard deviation was 5%. In addition, the Ag–PVA/CS nanofibers substrate was effective for recognition and detection of norfloxacin, a well-known antibiotic that is pertinent to food safety and animal/human health.
研究领域:
材料科学
·
分析化学
✓ 已验证
DOI
高影响因子
Friction
·
2022
·Vol. 11
·期 4
·513-523
·
IF 4.924
Gao Tianyang,Li Jinjin,Wang Weiqi,Luo Jianbin
An extremely low friction state was observed on the gold surface induced by applying a specific negative potential in cationic surfactant solution. The friction force showed a remarkable reduction from 8.3 to 3.5 × 10 −2 nN (reduced by 99.6%) with increasing the period of negative applied potential, and the final friction coefficient could reduce down to 3 × 10 −4 . The extremely low friction state was robust, and it also exhibited an excellent load bearing capacity, which cannot be damaged by a high load. Moreover, the extremely low friction state achieved under negative applied potential could keep stable even after the removal of potential, but failed in a short time, once a specific positive potential was applied. It was demonstrated that there was a stable electro-adsorption of surfactant molecules on the gold surface induced by applying a negative potential, leading to the formation of a bilayer structure on the gold surface. The hydration layers of the bilayer on the gold surface and micelles on the silica probe provided a shear plane with an extremely low shear strength, leading to the extremely low friction state on the gold surface. This study provides a method to achieve extremely low friction state by applied potential.
研究领域:
材料科学
·
界面化学
✓ 已验证
DOI
高影响因子
JOURNAL OF APPLIED ELECTROCHEMISTRY
·
2020
·Vol. 50
·期 5
·621-630
·
IF 2.384
Wang Yuyang,Zheng Hongtao,Lin Cunguo,Zheng Jiyong,Chen Ye,Wen Qing,Wang Shuang,Xu Haitao,Qi Lijuan
The structure and biocompatibility of anode materials significantly affect the performance of microbial fuel cells (MFCs). A biocompatible polyaniline–sodium alginate (PANI–SA) composite was prepared in situ oxidation polymerization on the 3D porous nitrogen-doped carbon nanotube/sponge (NCNT/S) to construct a high-performance microbial fuel cell in this investigation. The SEM showed that PANI–SA composite anode had a three-dimensional macroporous structure, and nitrogen-doped nanotubes were wound around the sponge skeleton, which had a large specific surface area, provided more places for the attachment and growth of microorganisms. A dual-chamber MFC equipped with a PANI–SA/NCNT/S bioanode to achieve a power density of 4380 mW m −3 , which was much greater than the other MFCs. During the charge–discharge time of 60–90 min, the PANI–SA/NCNT/S bioanode had the highest total charge value of 26,617.86 C m −2 , which was 3.23 times higher than that of NCNT/S (8231.87 C m −2 ). High-throughput sequencing results showed that the PANI–SA/NCNT/S bioanode exhibited high community diversity and selective enrichment of electrogenic bacteria. The excellent performance of the MFC equipped with PANI–SA/NCNT/S anode was attributed to the composite materials, which could be attributed to the large-pore network structure, better biocompatibility, large capacitance and high specific surface area. Graphic abstract
Illustration of the process for the preparation of PANI–SA
研究领域:
材料科学
·
环境工程
·
微生物学
✓ 已验证
DOI
高影响因子
CHINESE JOURNAL OF POLYMER SCIENCE
·
2013
·Vol. 31
·期 2
·201-210
·
IF 1.27
Zhang Shusheng,Chen Chongyi,Li Zhibo
We investigated the ring opening polymerization (ROP) of di- and tri-ethylene glycol monomethyl ether functionalized L-glutamate N -carboxyanhydrides (NCAs) using hexamethyldisilazane (HMDS) as primary initiator and 1,5,7-triazabicyclo-[4.4.0]dec-5-ene (TBD) as co-initiator. The binary initiator system afforded a living ROP for these pegylated NCAs, and a series of homopolypeptides with controlled molecular weight (MW) and low polydispersity were obtained. We then systematically studied the helical content and clouding point (CP) dependence on polypeptide MW using circular dichroism (CD) spectroscopy and turbidity measurements, respectively. We found that the helical content of both homopolypeptides increased with MW, but the triethylene glycol functionalized poly-L-glutamate (poly-L-EG 3 Glu) intended to form more stable α -helical structure than diethylene glycol functionalized counterpart (poly-L-EG 2 Glu) at similar MW. Accordingly, the CP of poly-L-EG 2 Glu with known end group has strong dependence on its helical content, which is essentially determined by MW. Our results suggested that the thermal responsive properties of these unique pegylated poly-L-glutamates not only rely on their chemical structure but also on their secondary structures, which is different from conventional thermal responsive polymers.
研究领域:
高分子化学
·
生物材料学
✓ 已验证
DOI
高影响因子
Nanoscale Research Letters
·
2012
·Vol. 7
·期 1
·1-7
·
IF 2.726
Zhang Jun,Zhao Su-Qing,Zhang Kun,Zhou Jian-Qing,Cai Yan-Fei
In the present work, ZnO quantum dots (QDs) have been prepared by the sol–gel method, and the performance of the QDs has been improved. The effect of Cd concentration on the structural and luminescent properties of the QDs, as well as the effect of the mass ratio of trioctylphosphine oxide (TOPO)/octadecylamine (ODA), has been investigated. The ZnO and Cd-doped ZnO QDs have hexagonal wurtzite structures and are 3 to 6 nm in diameter. When the Cd content was increased, the QD particle size was reduced; this effect was confirmed in the corresponding ultraviolet–visible spectra. The fluorescence intensity was simultaneously enhanced significantly. Both the UV and fluorescence spectra were blue-shifted. The luminous intensity was further enhanced when the QDs were modified with TOPO/ODA. Fourier transform infrared and X-ray diffraction techniques proved that the polymer successfully coated the surfaces of the QDs. A TOPO/ODA mass ratio of 1:2 was determined to result in the best optical performance among the different ratios examined. The results showed that the described synthetic method is appropriate for the preparation of doped QDs with high-fluorescence quantum efficiency.
✓ 已验证
DOI
高影响因子
MICROCHIMICA ACTA
·
2019
·Vol. 186
·期 2
·1-10
·
IF 5.479
Zhao Yanan,Zhou Juan,Jia Zimu,Huo Danqun,Liu Qingyan,Zhong Dengqin,Hu Yu,Yang Mei,Bian Minghong,Hou Changjun
A glassy carbon electrode was modified with a 3D-networked nanostructure composed of MoS 2 , reduced graphene oxide and gold nanoparticles (3D-MoS 2 /rGO/Au). The composites were prepared through in-situ growth of gold nanoparticles on 3D-MoS 2 /rGO nanosheets via a hydrothermal method. The morphology and electrochemical features of the composite were investigated. The 3D-MoS 2 /rGO/Au sensor exhibits excellent electrocatalytic activity for simultaneous detection of ascorbic acid (AA), dopamine (DA) and uric acid (UA). The oxidation potentials are well separated at around −0.05 V for AA, 0.06 V for DA and 0.2 V for UA, respectively. The detection limits for individual detection and simultaneous detection (S/ N = 3) are 0.93 μM and 1.46 μM for AA, 0.11 μM and 0.15 μM for DA, and 0.74 μM and 0.29 μM for UA. The method was applied to the quantitative analysis of AA, DA, and UA in spiked serum samples with satisfying results.
In-situ growth of gold nanoparticles on 3D-networked MoS 2 /rGO nanocomposite for individual and simultaneous determination of ascorbic acid, dopamine and uric acid.
研究领域:
材料科学
·
分析化学
·
生物医学
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）