JOURNAL OF MOLECULAR STRUCTURE
·
2026
·
IF 4.9
Qiang Zhao,Zhi Shen,Lin-Xi Qin,Meng-Ting Fan,Pei-Xuan Zhang,Xin-Yue Zhang
Complex 1 and 2 exhibit excellent red and green fluorescence, respectively. • Complexes 1 and 2 exhibit excellent selectivity towards Fe 3+ . • Complex 1 and 2 have good recognition of I - and F - in anions, respectively. • Complex 2 can achieve naked eye recognition of F - . To further advance research on rare earth complexes as Luminescent probes, this work investigates the cation and anion recognition capabilities of europium and terbium carboxylate complexes, Eu(ocpia) ( 1 ) and Tb(ocpia) ( 2 ), in dispersed systems. Cation recognition experiments were performed using DMF as the dispersion medium, with the complex concentration fixed at 0.2 mg/mL. Results demonstrate that both complexes 1 and 2 exhibit excellent selectivity for Fe³⁺, with detection limits as low as 0.076 μM and 0.069 μM, respectively. These findings indicate that complexes 1 and 2 hold great potential as fluorescent probes for Fe³⁺ detection. Anion recognition experiments were conducted in acetonitrile dispersion (0.2 mg/mL complex concentration). Complex 1 shows high selectivity for I⁻, achieving a detection limit of 0.052 μM. In contrast, complex 2 displays strong affinity for F⁻, with a detection limit of 0.087 μM. Notably, F⁻ can coordinate with complex 2 to form a soluble adduct, enabling visual, naked-eye recognition of F⁻. Collectively, these results highlight the promising application of complexes 1 and 2 as selective fluorescent probes for I⁻ and F⁻, respectively. Eu and Tb complexes exhibit excellent red and green fluorescence, respectively, and both have excellent recognition for Fe 3+ . Tb complex can experimentally recognize F - with naked eyes Download: Download high-res image (228KB) Download: Download full-size image
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高影响因子
Nanomaterials
·
2023
·Vol. 13
·期 6
·994
·
IF 5.3
Wei Dong,Qin Zhou,Wangqiang Shen,Le Yang,Peng Jin,Xing Lu,Yongfu Lian
Soot-containing terbium (Tb)-embedded fullerenes were prepared by evaporation of Tb4O7-doped graphite rods in an electric arc discharge chamber. After 1,2,4-trichlorobenzene extraction of the soot and rotary evaporation of the extract, a solid product was obtained and then dissolved into toluene by ultrasonication. Through a three-stage high-pressure liquid chromatographic (HPLC) process, Tb@C82(I, II) isomers were isolated from the toluene solution of fullerenes and metallofullerenes. With the success of the growth of cocrystals of Tb@C82(I, II) with Ni(OEP), the molecular structures of Tb@C82(I) and Tb@C82(II) were confirmed to be Tb@C2v(9)-C82and Tb@Cs(6)-C82, respectively, based on crystallographic data from X-ray single-crystal diffraction. Moreover, it was found that Tb@C82(I, II) isomers demonstrated different packing behaviors in their cocrystals with Ni(OEP). Tb@C2v(9)-C82forms a 1:1 cocrystal with Ni(OEP), in which Tb@C2v(9)-C82is aligned diagonally between the Ni(OEP) bilayers to form zigzag chains. In sharp contrast, Tb@Cs(6)-C82forms a 2:2 cocrystal with Ni(OEP), in which Tb@Cs(6)-C82forms a centrosymmetric dimer that is aligned linearly with Ni(OEP) pairs to form one-dimensional structures in the a–c lattice plane. In addition, the distance of a Ni atom in Ni(OEP) to the Cs(6)-C82cage is much shorter than that to the C2v(9)-C82one, indicative of a stronger π-π interaction between Ni(OEP) and the C82carbon cage in the cocrystal of Tb@CS(6)-C82and Ni(OEP). Density functional theory calculations reveal that the regionally selective dimerization of Tb@CS(6)-C82is the result of a dominant unpaired spin existing on a particular C atom of the CS(6)-C82cage.Keywords:metallofullerene;terbium;cocrystals;centrosymmetric dimer;unpaired spin
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TALANTA
·
2023
·
IF 6.1
Guibin Peng,Bixia Lin,Manli Guo,Yujuan Cao,Ying Yu,Yumin Wang
Deoxyribonuclease I (DNase I) is a typical nuclease that plays key roles in many physiological processes and the development of a novel biosensing strategy for DNase I detection is of fundamental significance. In this study, a fluorescence biosensing nanoplatform based on a two-dimensional (2D) titanium carbide (Ti 3 C 2 ) nanosheet for sensitive and specific detection of DNase I was reported. Fluorophore-labeled single-stranded DNA (ssDNA) can be spontaneously and selectively adsorbed on Ti 3 C 2 nanosheet through the hydrogen bond and metal chelate interaction between phosphate groups of ssDNA and titanium of Ti 3 C 2 nanosheet, resulting in effective quenching of the fluorescence emitted by fluorophore. Notably, it was found the enzyme activity of DNase I will be terminated by the Ti 3 C 2 nanosheet. Therefore, the fluorophore-labeled ssDNA was firstly digested by DNase I and the “post-mixing” strategy of Ti 3 C 2 nanosheet was chosen to evaluate the enzyme activity of DNase I, which provided the possibility of improving the accuracy of the biosensing method. Experimental results demonstrated that this method can be utilized for quantitative analysis of DNase I activity and exhibited a low detection limit of 0.16 U/ml. Additionally, the evaluation of DNase I activity in human serum samples and the screening of inhibitors with this developed biosensing strategy were successfully realized, implying that it has high potential as a promising nanoplatform for nuclease analysis in bioanalytical and biomedical fields.
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Journal of Cleaner Production
·
2023
·
IF 11.1
Jiayi Li,Weixing Han,Heyao Liu,Minhua Su,Diyun Chen,Gang Song
The development and use of clean energy produced by nuclear power plants is becoming a major international trend, but it will inevitably lead to the problem of radionuclide pollution. Radioactive nuclear wastewater containing Cs and U and produced as a byproduct of coastal nuclear power production can cause substantial environmental pollution . In order to simultaneously remove radioactive cesium and uranium, polydopamine (PDA) inlaid ammonium phosphomolybdate (AMP) has established a hydrophilic functional structural film on the surface of Fe 3 O 4 , forming AMP@PDA@Fe 3 O 4 (APF) which is used to simultaneous remove Cs(I) and U(VI). Using the pH sensitive range of APF adsorption in the process of adsorbing Cs(I) and U(VI), synergistic adsorption can be achieved under the condition of weak acidity to neutral. The effects of temperature, and common cations on Cs(I) and U(VI) adsorption by APF were investigated, the adsorption was found to be sensitive to the presence of K + . The efficiency of Cs(I) and U(VI) adsorption by APF was 99.88% and 98.39%, respectively. The Cs(I) adsorption process was primarily ion exchange with NH 4 + within APF composite, whereas that for U(VI) was primarily C-O complexation. Both the Cs(I) and U(VI) adsorption reactions were consistent with second-order kinetic and Langmuir isothermal adsorption models. After five cycles of experiments the removal efficiency of Cs(I) and U(VI) can reach 64.88% and 79.81%, respectively. APF was also found to have high selectivity for Cs and U in seawater with high salt content at pH 6.0–7.0. In mimic contaminated seawater, the efficiency of Cs(I) and U(VI) removal was 97.65% and 84.63%, respectively. These findings provide references for the remove of Cs(I) and U(VI) from radioactive wastewater , making the process of energy production safer.
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Journal of Materials Chemistry A
·
2023
·Vol. 11
·期 12
·6168-6180
·
IF 11.9
Yifan Chen,Jinze Wang,Youran Hong,Yusi Yang,Lulu Tan,Nan Li,Can Ma,Jiangwei Wang,Xiulin Fan,Yujie Zhu
Recently, to enhance the low-temperature performance of lithium-ion batteries (LIBs), significant efforts have been devoted to developing novel electrolytes with low viscosities, high conductivities, and facile Li-ion desolvation, while much less attention is paid to exploring optimum electrode materials for low-temperature LIBs. In this contribution, we discover that commercial microsized Cu2S exhibits a remarkably high performance toward lithium storage under ultra-low temperatures. Under room temperature, it delivers a reversible specific capacity of 318.8 mA h g−1 with very flat lithiation–delithiation plateaus around 1.75 V in Li metal cells. At −60 °C and a galvanostatic charge–discharge rate of 0.3C, it could still provide a reversible specific capacity of 168.8 mA h g−1 with stable cycling performance, promising its application in ultra-low-temperature Li-based batteries. Through a combination of microscopic, spectroscopic, and electrochemical characterization bolstered by theoretical calculations, the detailed reaction mechanisms and mechanistic understanding of the excellent low-temperature performances are proposed. This work points out the great opportunities to enhance the low-temperature performance of LIBs by discovering suitable electrode materials.
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Biosensors-Basel
·
2022
·Vol. 12
·期 12
·1108
·
IF 5.743
Ding Wang,Yiru Zhao,Shen Zhang,Liping Bao,Huijun Li,Jingcheng Xu,Bin He,Xumin Hou
Rapid and accurate detection of acute myocardial infarction can improve patients’ chances of survival. Cardiac troponin I (cTn I) is an important diagnostic biomarker for acute myocardial infarction. However, current immunoassays are insufficient to accurately measure cTn I, as they have limited detection sensitivity and are time-consuming. Surface-enhanced Raman scattering (SERS) is a brilliant fingerprints diagnostic technique characterised by ultrasensitivity, fast response, and qualitative and quantitative analysis capabilities. In this study, reporter molecules (4-Mercaptobenzoic acid, 4-MBA) embedded[email protected]core-shell nanospheres as SERS nanotags were prepared for the detection of cTn I. As the Raman reporters were embedded between the core and the shell, they could be protected from the external environment and nanoparticle aggregation. Excellent SERS performances were obtained due to the enhanced local electromagnetic field in the gap of core and shell metals. In a standard phosphate buffered saline (PBS) environment, the limit of detection for cTn I was 0.0086 ng mL−1(8.6 ppt) with a good linear relationship. The excellent Raman detection performance was attributed to the localized surface plasmon resonance effect and strong electromagnetic field enhancement effect produced by the gap between the Au core and the Ag shell. The SERS nanotags we prepared were facile to synthesize, and the analysis procedure could be completed quickly (15 min), which made the detection of cTn I faster. Therefore, the proposed SERS nanotags have significant potential to be a faster and more accurate tool for acute myocardial infarction diagnostics.Keywords:[email protected]nanospheres;GERTs;SERS;cTn I detection;AMI
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BMC CANCER
·
2022
·Vol. 22
·期 1
·1-12
·
IF 4.638
Chen Xueqin,Wang Yan,Liu Hancong,Zhang Jingjing,Wang Jie,Jin Xiaobao,Ma Yan
Background In our previous study, N end of the Circumsporozoite protein (CSP I-plus) modified recombinant human Endostatin (rEndostatin, endostar) (rES-CSP) was constructed, which had antiangiogenic capability and bound to hepatocellular carcinoma in vivo and in vitro. In this study, the inhibition of rES-CSP on hepatocellular carcinoma metastasis was verified in vivo and in vitro, and its possible mechanism was explored. Methods Firstly, the impact of rES-CSP on the migration, adhesion of hepatoma cell HCCLM3 was identified by wound healing, transwell, and on metastasis of orthotopic xenograft model was identified in nude mouse. Then the expression of metastasis-associated molecules (MMP2, E-cadherin, integrinβ1) and angiogenesis-related factors (VEGFA) in vitro and in vivo were detected by real-time PCR, western blotting, immunohistochemistry. Results Finally, we found that rES-CSP could inhibit the migration and invasion of HCCLM3, and decrease tumor metastasis and growth in nude mouse orthotopic xenograft models. The tumor inhibiting rates of rES-CSP and Endostar were 42.46 ± 5.39% and 11.1 ± 1.88%. The lung metastasis rates of the control, Endostar and rES-CSP were 71, 50, and 42.8%, respectively. Compared with Endostar, rES-CSP significantly down-regulated the expression of VEGFA and integrinβ1. Heparin, a competitive inhibitor of CSP I-plus, which can be bind to the highly-sulfated heparan sulfate proteoglycans (HSPGs) over-expressed in liver and hepatocellular carcinoma, alleviated the down-regulation of VEGFA and integrinβ1. Conclusions These indicate that rES-CSP may play a role in inhibiting tumor growth and metastasis by down-regulating the angiogenic factor VEGF and the metastasis-related molecules or by interfering with HSPGs-mediated tumor metastasis.
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ENVIRONMENTAL SCIENCE & TECHNOLOGY
·
2023
·
IF 11.4
Xiangrui Wang,Wen-Xiong Wang
Cu-based nanoparticles (NPs) have been increasingly fabricated, and different Cu species (i.e., Cu+ and Cu2+) of these NPs are tuned to achieve differential physicochemical properties. Although ion release is one of the major toxic mechanisms of Cu-based NPs, differences in cytotoxicity between released Cu(I) and Cu(II) ions are largely unknown. In this study, the A549 cells exhibited a lower tolerance to Cu(I) compared with Cu(II) accumulation. Bioimaging of labile Cu(I) indicated that the change of the Cu(I) level upon CuO and Cu2O exposure displayed different trends. We then developed a novel method to selectively release Cu(I) and Cu(II) ions within the cells by designing CuxS shells for Cu2O and CuO NPs, respectively. This method confirmed that Cu(I) and Cu(II) exhibited different cytotoxicity mechanisms. Specifically, excess Cu(I) induced cell death through mitochondrial fragmentation, which further led to apoptosis, whereas Cu(II) resulted in cell cycle arrest at the S phase and induced reactive oxygen species generation. Cu(II) also led to mitochondrial fusion, which was likely due to the influence of the cell cycle. Our study first uncovered the difference between the cytotoxicity mechanisms of Cu(I) and Cu(II), which could be greatly beneficial for the green fabrication of engineered Cu-based NPs.
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高影响因子
Nature Communications
·
2022
·Vol. 13
·期 1
·1-16
·
IF 17.694
Li Mingyang,Jin Xinyang,Liu Tao,Fan Feng,Gao Feng,Chai Shuang,Yang Lihua
Nanoparticle elasticity is crucial in nanoparticles’ physiological fate, but how this occurs is largely unknown. Using core-shell nanoparticles with a same PEGylated lipid bilayer shell yet cores differing in elasticity (45 kPa – 760 MPa) as models, we isolate the effects of nanoparticle elasticity from those of other physiochemical parameters and, using mouse models, observe a non-monotonic relationship of systemic circulation lifetime versus nanoparticle elasticity. Incubating our nanoparticles in mouse plasma provides protein coronas varying non-monotonically in composition depending on nanoparticle elasticity. Particularly, apolipoprotein A-I (ApoA1) is the only protein whose relative abundance in corona strongly correlates with our nanoparticles’ blood clearance lifetime. Notably, similar results are observed when above nanoparticles’ PEGylated lipid bilayer shell is changed to be non-PEGylated. This work unveils the mechanisms by which nanoparticle elasticity affects nanoparticles’ physiological fate and suggests nanoparticle elasticity as a readily tunable parameter in future rational exploiting of protein corona.
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ENVIRONMENTAL RESEARCH
·
2022
·
IF 8.431
Fa Fang,Nuo Li,Xian Zhang,Juan Liu,Jingzi Beiyuan,Jielong Cao,Jin Wang,Yanyi Liu,Gang Song,Tangfu Xiao
Due to extreme toxicity of the element of thallium (Tl), increasing aqueous Tl pollution incidents have aroused growing concerns. As the prevalent and stable form, i.e. , monovalent Tl, the highly efficient removal methodologies of Tl(I) from (waste)water remains limited and challenging. In this study, an advanced oxidation method, the feasibility of using zero valent iron (Fe 0 ) coupled with persulfate (PS) to treat Tl(I)-containing synthetic wastewater was investigated. Its influence parameters, including reaction time, initial Tl concentration, dosages of PS and Fe 0 , initial and coagulation pH, temperature, coexisting ions and organic matter (NO 3 − , SO 4 2− , Cl − and HA) were examined. The results revealed that the system can be applied to a wide range of pH and temperature and the reaction equilibrium can be reached in about 30 min. Favorable Tl(I) removal rate (>98%) was observed in the synthetic wastewater with medium and relatively high Tl(I) concentration (≤0.250 mM). The analyses of characterization results including electron spin resonance spectrometer and X-ray photoelectron spectroscopy indicated that ·OH played a vital role in the removal of Tl(I), which was oxidized and removed by co-precipitation. Fe 0 can be served as a stable source of Fe 2+ to efficiently catalyze PS. The remaining Fe 0 can be easily separated because of its magnetism, assuring the promising reusability of the reactant. The study aims to provide references for treatment of real Tl polluted wastewater.
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PROGRESS IN ORGANIC COATINGS
·
2022
·
IF 6.206
YinPing Wu,Rui Li,Chenguang Huang,Jiu Wu,Xian Sun,Yue Situ,Hong Huang
Two low migration acylphosphine oxide photoinitiators (APO and DAPO) containing unsaturated C C double bonds have been designed and synthesized for free radical polymerization . The properties and performances of APO and DAPO in the free radical polymerization of trimethylolpropane triacrylate (TMPTA) were evaluated and compared with the commercial photoinitiator 2,4,6-trimethyl(phenyl) diphenyl oxide (TPO). The results show that DAPO exhibited the best double bond conversion (DC) of TMPTA in the photoinitiators tested under the same reaction conditions. The migration ratio of APO and DAPO was 2/3 and 1/3 of that of TPO respectively indicating lower migration than the conventional photoinitiator, and the solubility of DAPO in monomers was close to that of TPO, which provided the possibility for the industrial application of DAPO.
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ChemSusChem
·
2022
·Vol. 15
·期 14
·e202200337
·
IF 9.14
Li-Qi Qiu,Zhi-Wen Yang,Xiangyang Yao,Xiao-Yang Li,Liang-Nian He
Graphical CO 2 photoreduction : Toward building robust artificial photosynthetic systems, a series of single-active-site rhenium bipyridyl complexes with dipyrromethene-BF 2 units exhibit outstanding catalytic efficiency for visible light-driven-CO 2 reduction. New rhenium bipyridyl complexes with dipyrromethene-BF 2 chromophores (A-ReBDP-CZ, A-ReBDP 2 , ReBDP-CZ, and ReBDP 2 ) were developed for highly efficient photocatalytic carbon dioxide (CO 2 ) reduction to carbon monoxide (CO). These catalysts consisted of two moderate electron-deficient groups (dipyrromethene-BF 2 , BDP) as the visible-light-harvesting antenna as well as both electron donor ( N -phenylcarbazole, CZ) and acceptor (BDP) on Re bipyridyl framework. Among ReBDP-CZ and ReBDP 2 complexes, the ReBDP 2 incorporating two electron-deficient BDP chromophores had a longer-lived photoexcited state (182.4 μs) and a twofold enhanced molar absorption coefficient ( ϵ =157000 m −1 cm −1 ) compared with ReBDP-CZ. Thus, ReBDP 2 achieved the superior photocatalytic reactivity and stability with a CO turnover number (TON CO ) value as high as 1323 and quantum yield ( Φ CO ) up to 55 %, which was the most excellent photocatalysis efficiency among the single-active-site Re catalysts without additional photosensitizer. Furthermore, the acetylene-bridged linker was detrimental to the photoactivity and durability of the catalyst. In brief, two BDP-based Re bipyridyl systems with outstanding catalytic performance and significant visible-light-harvesting capabilities in the solar spectrum offer a promising strategy for solar-to-fuel conversion schemes.
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危险品化学品经营许可证（带存储）