APPLIED SURFACE SCIENCE
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2019
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IF 5.155
Donghui Xu,Wenyan Chen,Yilin Luo,Hongshan Wei,Chujun Yang,Xin Cai,Yueping Fang,Xiaoyuan Yu
SiO x (0 < x < 2) based materials are attractive for developing high-capacity and durable anodes toward superior lithium storage. Herein, low cost and tailorable core-shell SiO@TiO 2 nanocomposites have been synthesized via simple ball milling and sol-gel process. The designed nanocomposite is composed of nano-sized SiO as the inner core and amorphous TiO 2 layer as the shell. Remarkably, when used as anode material for lithium-ion batteries, the SiO@TiO 2 exhibits greatly enhanced capacity performance and cycling stability due to its rational core-shell structure. The optimal nanocomposite delivers a high initial specific capacity of 1920 mA h g −1 with high initial coulombic efficiency of 79.4%, along with a stable reversible capacity of 901 mA h g −1 after 200 cycles at 200 mA g −1 and impressive high-rate capacity of 272 mA h g −1 at 3000 mA g −1 . The excellent electrochemical performance of the nanocomposite is contributed by the synergetic core-shell structure, in which the amorphous TiO 2 shell can not only act as protective/elastic buffer layer to accommodate the volume change of the SiO nanoparticles upon cycling, but also largely favor the Li + diffusion in the nanocomposite toward highly reversible lithium storage. In virtue of the simple, green and scalable fabrication process, these robust and efficient nanocomposites are promising to realize inexpensive and high-performance lithium ion batteries anodes and related energy storage applications .
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ACS Applied Materials & Interfaces
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2021
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IF 9.229
Hongshun Zhao,Yanli Qi,Kang Liang,Jianbin Li,Liangyan Zhou,Jinyuan Chen,Xiaobing Huang,Yurong Ren
Cobalt diselenide (CoSe2) has drawn great concern as an anode material for sodium-ion batteries due to its considerable theoretical capacity. Nevertheless, the poor cycling stability and rate performance still impede its practical implantation. Here, CoSe2/nitrogen-doped carbon-skeleton hybrid microcubes with a TiO2 layer (denoted as TNC-CoSe2) are favorably prepared via a facile template-engaged strategy, in which a TiO2-coated Prussian blue analogue of Co3[Co(CN)6]2 is used as a new precursor accompanied with a selenization procedure. Such structures can concurrently boost ion and electron diffusion kinetics and inhibit the structural degradation during cycling through the close contact between the TiO2 layer and NC-CoSe2. Besides, this hybrid structure promotes the superior Na-ion intercalation pseudocapacitance due to the well-designed interfaces. The as-prepared TNC-CoSe2 microcubes exhibit a superior cycling capability (511 mA h g–1 at 0.2 A g–1 after 200 cycles) and long cycling life (456 mA h g–1 at 6.4 A g–1 for 6000 cycles with a retention of 92.7%). Coupled with a sodium vanadium fluorophosphate (Na3V2(PO4)2F3)@C cathode, this assembled full cell displays a specific capacity of 281 mA h g–1 at 0.2 A g–1 for 100 cycles. This work can be potentially used to improve other metal selenide-based anodes for rechargeable batteries.
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JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
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2026
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IF 16.8
Fei Sun,Xuan Li,Kaining Zhang,Guozheng Yang,Zaitian Wang,Huawan Chen,Fei Long,Tong Zhou,Lie Liu
Photocatalytic TiO 2 granular networks provide copper anchoring sites. • PSZ coordinates surface roughness and bond strength. • Si 3 N 4 -based CCLs exhibit a bond strength of 2.35 MPa at a Sa value of 0.44 μm. • Signal attenuation reduced from 6.446 to 5.963 dB/m. Developing high-frequency ceramic-based copper clad laminates (CCLs) is constrained by the roughness-adhesion trade-off: Pursuing ultralow interfacial roughness for signal integrity compromises essential bond strength. Conventional active metal brazing enables robust bonding but often degrades signal integrity through process-generated interfacial voids and surface roughening. Herein, a solution-processed photocatalytic titanium dioxide (TiO 2 )/polysilazane (PSZ) hybrid interlayer was developed to bridge copper with silicon nitride (Si 3 N 4 ) substrates. In this biphasic system, TiO 2 nanoparticles assemble into a granular network, providing photocatalytic sites for copper deposition and mechanical interlocking. Meanwhile, PSZ strengthens interlayer cohesion and establishes interlayer-substrate adhesion, synergistically addressing the roughness-adhesion trade-off with the TiO 2 network. Optimizing the TiO 2 /PSZ ratio yielded Si 3 N 4 -based CCLs with a bond strength of 2.35 MPa at a low roughness (Sa) of 0.422 µm. The signal attenuation was reduced from 6.446 to 5.963 dB/m. This architecture provides a cost-efficient and scalable route for ceramic-based high-frequency and high-speed signal interconnects with controlled interfacial roughness. Download: Download high-res image (232KB) Download: Download full-size image
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JOURNAL OF NANOBIOTECHNOLOGY
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2026
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IF 15
Liang Lei,Aixiang Wang,Liping Dong,Tao Wu,Wenjuan He,Yonghui Yang,Jing Li,Xiaobin Bi,Yuan Cai,Xinlei Guan,Xiaoqiang Zhu
The use of titanium dioxide (TiO 2 ) as a food additive has persistently elicited concerns about its potential toxicity, primarily attributed to the significant presence of nanoparticles. Studies have recently demonstrated that nano- or micro-sized food-grade TiO 2 (fg-TiO 2 ) particles can disrupt gut microbial balance and weaken the intestinal barrier; however, the underlying mechanisms remain poorly understood. Furthermore, research on dietary interventions for repairing fg-TiO 2 -induced intestinal injury is limited. This study delved into the role of the interactions among gut microbes, indole-3-lactic acid (ILA) and mucin sulfation in fg-TiO 2 -induced intestinal mucosal barrier damage through multi-omics analysis, and revealed the protective effects of quercetin. Prolonged oral administration of fg-TiO 2 at doses pertinent to human exposure resulted in notable intestinal inflammation and mucosal barrier damage through diminishing mucin sulfation. Further analysis demonstrated that fg-TiO 2 caused significant gut microbiota dysbiosis and metabolite changes. It was found that Lactobacillus and its metabolite ILA, an aryl hydrocarbon receptor (AHR) agonist, was significantly downregulated following oral ingestion of fg-TiO 2 , which decreased the activation of AHR and ultimately led to a loss in mucin sulfation in colon tissues. Notably, experiments involving fecal microbiota transplantation (FMT) and ILA supplementation indicated gut microbial shifts and the consequent decrease in colonic ILA levels were accountable for the detrimental effects of fg-TiO 2 on mucin sulfation and intestinal barrier integrity. Moreover, this study found that dietary intervention with quercetin could effectively reverse the damage to the intestinal mucosal barrier induced by fg-TiO 2 through targeting gut microbiota-ILA-mucin sulfation axis. This research uncovered the adverse impacts of fg-TiO 2 on gut homeostasis and indicates the potential of quercetin to combat the intestinal toxicity of fg-TiO 2 . These findings enhanced our comprehension of the safety profile of fg-TiO 2 and proposed a nutritional approach to mitigate the health risks associated with fg-TiO 2 exposure.
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PubMed
高影响因子
BMEMat
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2026
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IF 17.2
Kairui Liu,Bo Zhang,Yue Wan,Zhiru Yang,Abdusami Abdurahman,Mengxin He,Shengtao Hu,Yi Zhang,Xiaoke Li,Jin Chang,Jun Kang,Liren Liu,Wanghua Liu,Shao Li
Hepatocellular carcinoma (HCC), ranking as the third leading cause of cancer-related mortality globally, continues to pose significant therapeutic challenges. Here, we developed an innovative nanosystem, Phl@PT, based on Pt-TiO 2 nanoparticles for the co-delivery of Phlorezin, presenting a novel approach for HCC treatment through sonodynamic therapy (SDT). Phl@PT demonstrated remarkable efficacy in inducing mitochondrial membrane potential collapse and cristae damage in vitro. Transcriptomic sequencing analysis revealed that Phl@PT treatment led to the downregulation of key genes: CLDN6 , involved in the cell adhesion molecules pathway, and BCKDHB and SUCLG2 , associated with propanoate metabolism. Through a comprehensive target fishing strategy combined with Bio-Layer Interferometry analysis, we identified DDX5, a DEAD-box RNA helicase, as a novel target protein of Phlorezin, which plays a crucial role in tumor progression and prognosis. In vivo studies demonstrated that US-activated Phl@PT not only effectively inhibited HCC growth in murine models but also activated CD8 + /CD4 + T cells, promoted dendritic cell maturation, and enhanced the expression of key immune cytokines including TNF-α, IL-12, and IFN-γ, thereby establishing a robust immunotherapeutic response. Collectively, our findings demonstrate that the Pt-TiO 2 mesoporous nanoagent co-delivering phlorezin represents a promising therapeutic platform for HCC treatment through synergistic sonodynamic-chemo-immunotherapy.
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ELECTROCHIMICA ACTA
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2026
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IF 5.8
Bowen Li,Liyang Qin,Weihua Ma,Binbin Yao,Jiahao Wang,Ye Song,Qianqiao Chen,Chengyuan Li,Xufei Zhu
The recombination of photogenerated carriers limits the photoelectrochemical (PEC) efficiency of titanium dioxide (TiO 2 ) nanotubes. To address this, we constructed a type Ⅱ ZnO/TiO 2 heterostructure via in situ hydrothermal loading of ZnO nanoparticles onto highly ordered anodic TiO 2 nanotube arrays. A critical interplay between precursor soaking duration (1 day vs. 5 days) and hydrothermal temperature (120 °C vs. 150 °C) was uncovered, that is, prolonged soaking and lower hydrothermal temperatures were beneficial for enhancing photocurrent. A two-step annealing process utilized in this work can enhance precursor infiltration into the nanotube channels, promoting uniform ZnO nucleation and robust interfacial adhesion. The optimized heterostructure electrode achieved a nearly twofold increase in carrier concentration (from 5.56 × 10 18 to 1.14 × 10 19 cm -3 ) along with reduced charge-transfer resistance and enhanced charge separation efficiency compared to unmodified TiO 2 . Electrochemical impedance spectroscopy study revealed that the modified heterostructure electrode exhibits lower surface charge-transfer resistance and higher bottom barrier-layer resistance than the unmodified electrode, thereby facilitating efficient interfacial charge transfer and suppressing dark current. Using glucose as a probe, the modified electrode delivered a higher photocurrent density and a faster response than the unmodified one. This work provides an alternative approach to optimizing semiconductor heterojunctions, and the improved process demonstrates promising potential for glucose sensing applications.
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Catalysts
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2026
·Vol. 16
·期 6
·494
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IF 4.5
Zijie Chen,Jinyang Chen
A series of Mg-Al LDH-based photocatalysts were synthesized via a one-pot steam-assisted method, including pure Mg-Al LDH (MA), Zn-In ion-exchange-modified Mg-Al LDH (MAZ), BiOCl-loaded pristine Mg-Al LDH (MAB), and Zn-In-modified Mg-Al LDH co-loaded with TiO2and BiOCl (MA/Zn-In/TiO2/BiOCl, MAZB). The one-pot synthesis facilitated the in situ intercalation and uniform loading of BiOCl/TiO2/Zn-In, while Zn2+/In3+modified the MA layers via ion exchange, leading to an expansion of the interlayer spacing. The innovation of this work is reflected in two aspects: first, all raw materials are added via a one-pot strategy to achieve in situ preparation of modified hydrotalcite; second, this synthetic route features simple post-treatment without complicated washing, pressure filtration, and other tedious operations. The samples were characterized by X-ray diffraction (XRD), Fourier transform infrared (FTIR) spectroscopy, scanning electron microscopy (SEM), transmission electron microscopy (TEM), X-ray photoelectron spectroscopy (XPS), and N2adsorption–desorption isotherms. The bismuth chloride oxide/TiO2/LDHs exhibited a layered structure, with the active components uniformly distributed between the layers and on the MA surface. Under simulated sunlight irradiation, MAZB achieved 97.5% degradation of 20 mg/L MB within 120 min, with an apparent rate constant of 0.0297 min−1, which is 7.2 times, 2.4 times, and 2.9 times that of MA, MAZ, and MAB, respectively. The degradation rate of MAZB still remained at 89.5% after five cycles, demonstrating excellent stability and reusability. Compared with traditional hydrothermal methods, this steam-assisted system features mild reaction conditions (180 °C, atmospheric pressure), sodium-free raw materials, no washing requirement, and zero waste discharge, showing prominent green advantages.
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SEPARATION AND PURIFICATION TECHNOLOGY
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2025
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IF 9
Yonghui Yang,Wanzhang Yang,Hengwei Yan,Zhanwei Liu,Shenghui Guo,Wenhui Ma,Mingyi Hu,Rui Xia,Jiahao Zheng,Wenrong Wang
Electrochemical reduction of TiO 2 in NaF–K 2 TiF 6 -based molten salts offers a low-energy pathway for titanium production but generates fluoride-rich by-products (e.g., NaF, K 2 NaTiF 6 ), leading to contamination of titanium powder with hazardous species (F − , Na + , K + ). In this work, an aluminum salt-assisted selective leaching and co-precipitation method was developed to remove these impurities and recover valuable components. Key process parameters—including leaching temperature, leaching time, acid concentration, Al 3+ dosage, and liquid–solid ratio—were systematically optimized, achieving fluoride, sodium, and potassium removal efficiencies exceeding 95 %. The purified titanium exhibited significantly reduced fluoride residues. Meanwhile, the leachate was converted into high-purity anatase TiO 2 via hydrolysis and calcination, providing a potential feedstock for subsequent electrolysis. By-products such as Al 2 O 3 –AlF 3 mixtures, cryolite (Na 3 AlF 6 ), and Na 2 SO 4 were recovered from the filtrates. The residual leaching solution was recycled to establish a closed-loop process. This integrated separation and purification approach enables efficient decontamination, resource recovery, and sustainable management of fluoride-rich molten salt systems.
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Acta Biomaterialia
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2025
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IF 9.6
Shengming Wu,Chenlong He,Huawei Liu,Han Zhou,Jingwen Qin,Ming Yin,Muqing Yang,Wenjie Tang,Yilong Wang
Tumor catalytic therapy is challenged by uncontrolled reaction sites and limited radical diffusion, leading to both safety concerns and insufficient therapeutic depth. Here, we develop an injectable UCNPs@TiO 2 –nitrate hydrogel system that enables intratumoral, in situ generation of long-lived nitrate radicals (•NO 3 , t 1/2 ≈ 60 μs) with superior diffusion capability under near-infrared (NIR) irradiation. In this system, upconversion nanoparticles convert 980 nm NIR light into ultraviolet (UV) emission, which activates TiO 2 to generate oxidative holes that catalyze NO 3 - into •NO 3 . The hydrogel matrix spatially confines radical generation within the tumor site, achieving controlled and sustained release. Compared to conventional short-lived •OH systems, •NO 3 exhibits enhanced penetration and prolonged reactivity, and its combination with •OH provides synergistic oxidative damage. In vitro and in vivo results demonstrate that the dual-radical system significantly improves tumor suppression while maintaining favorable biocompatibility. This work offers a robust strategy to overcome the diffusion and safety limitations of conventional catalytic therapy by achieving spatiotemporally confined and synergistic radical generation within tumors. Statement of Significance This study introduces a hydrogel platform that converts near-infrared light into UV to activate TiO 2 and generate long-lived nitrate radicals (•NO 3 ) in vivo . These radicals offer extended lifetime and reactivity, allowing deeper tumor penetration compared to traditional short-lived species like •OH. The system achieves spatiotemporally controlled radical release at tumor sites, enhancing catalytic therapy precision. A dual-radical strategy combining •NO 3 and •OH further boosts therapeutic efficacy. Importantly, this approach shows minimal systemic toxicity and strong translational potential. These findings expand the reactive species toolbox and offer a promising direction for radical-based cancer therapy.
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PubMed
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
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2025
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IF 5.4
Qiuyang Zhang,Ruirui Ma,Kunpeng Jia,Shunhang Dong,Jie Chen,Changjiang Pan
Titanium and its alloys, as the most prevalent materials for orthopedic implants, face two critical challenges in clinical practice: inadequate osseointegration and susceptibility to bacterial infection. To resolve these issues, a multifunctional coating (TNT+XGPP) was developed on Ti implants via three steps: electrochemical anodization to construct TiO 2 nanotube (TNT), hydrothermal loading of bone-affinity Ga 3+ ions (TNT+XG) at different concentrations, and carbodiimide-mediated grafting of γ-polyglutamic acid (γ-PGA) via a polydopamine intermediate layer. The morphology, composition, surface wettability, and ion release behavior of the prepared coatings were thoroughly characterized. The coatings were assessed for early-stage osteoblast growth behavior, Ca-P apatite formation capacity, and antibacterial activity. The characterization results confirmed that Ga 3+ ions and γ-PGA were successfully incorporated into TiO 2 nanotubes, significantly enhancing hydrophilicity. The TNT+XGPP coating, in conjunction with the nanotubes, Ga 3+ ions at appropriate concentrations (5, 20, and 50 mM), and γ-PGA, not only facilitated osteoblast adhesion and proliferation, but also upregulated the expression of osteogenic functional factors (e.g., alkaline phosphatase, osteocalcin, and runt-related transcription factor-2). In contrast, an elevated concentration of Ga 3+ ions (100 mM) in the coating exerted a certain inhibitory effect against osteoblast growth. The TNT+XGPP coating accelerated the in-situ deposition of bone-like Ca-P apatite, attributing to the synergy of γ-PGA and Ga 3+ ions. The released Ga 3+ ions exerted remarkable antibacterial effects against E. coli and S. aureus , with their concentration positively associated with antibacterial activity. This work offers a novel strategy for enhancing the bone affinity and antibacterial properties of Ti-based orthopedic implants.
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Catalysis Science & Technology
·
2026
·
IF 4.2
Tao Liu,Zhenjie Xu,Guangming Zhou,Simiao Yu,Jie Liu,Jian Ke,Gang Lu
Chemical excess sludge, containing viruses, heavy metals, polycyclic aromatic hydrocarbons, and other components, exhibits high toxicity, making its safe disposal an urgent issue. In this work, MIL-100 (Materials of Institut Lavoisier – 100(iron)) was synthesized using 1,3,5-benzenetricarboxylic acid and iron extracted from excess sludge. Additionally, titanium dioxide was loaded onto MIL-100 via an impregnation–calcination method to form T@MIL-100, and their visible-light-driven photocatalytic activities for methylene blue (MB) degradation were evaluated. The results showed that the synthesized MIL-100 exhibited excellent photocatalytic performance for MB degradation, with a degradation efficiency of 92.44% and a corresponding kinetic constant (kobs) of 0.97612 h−1. The degradation efficiency of MB over 1%T@MIL-100 was enhanced to 98.42%, and the kobs value increased to 1.39943 h−1. Quenching experiments further revealed the catalytic mechanism: h+ was the dominant active species in the MIL-100 system, while ·O2− and h+ primarily contributed to MB degradation in the T@MIL-100 system. This study provides a low-cost, efficient, and sustainable approach to convert excess sludge into functional metal–organic frameworks (MOFs) and further load TiO2. This strategy not only promotes the recycling of residual iron in excess sludge to significantly reduce catalyst costs, but also enhances photocatalytic degradation performance, offering an excellent functional material for MB removal.
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JOURNAL OF PHYSICS AND CHEMISTRY OF SOLIDS
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2020
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IF 3.442
Song Chen,Juan Du,Lulu Shen,Weiyi Chen
Hierarchical materials are of great interest toward the development of catalysts because of their unique structures and large specific surface area. In this study, Ag-decorated TiO 2 (TiO 2 @Ag) nanowire nanofibers (NW NFs) were synthesized via the in situ decoration of Ag nanoparticles (NPs) on hierarchical TiO 2 NW NFs and their microstructure and catalytic activity for the removal of 4-nitrophenol were evaluated. TiO 2 NW NFs were first synthesized via the hydrothermal reaction of the electrospun TiO 2 NFs in a concentrated NaOH solution and then hydrothermally treated in a AgNO 3 solution to form the TiO 2 @Ag NW NFs. SEM observations showed that the TiO 2 @Ag NW NFs were assembled from numerous TiO 2 NWs subunits and exhibited a hierarchical and fibrous morphology with diameters in the range of 1–2 μm and lengths of tens of micrometers. TEM observations showed that many Ag NPs with diameters in the range of 4–10 nm were well grown on each TiO 2 NW with diameters of 20–40 nm. It was found that the TiO 2 @Ag NW NFs showed catalytic activity for the removal of 4-nitrophenol (4-NP), a representative contaminant. The catalytic removal efficiency of 4-NP by the TiO 2 @Ag NW NFs in the presence of visible light irradiation (0.639 min −1 ) was 3.2-fold higher than that in the absence of light irradiation (0.199 min −1 ), indicating that the TiO 2 @Ag NW NFs exhibit visible light-enhanced catalytic activity.
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